NCT00004795

Who might be able to join this trial:

• You have been diagnosed with systemic lupus erythematosus (lupus) based on recognised medical guidelines
• Your lupus is considered mild to moderate in severity
• You are taking prednisone (or a similar steroid medication) at a dose between 10 and 30 mg per day — not on an every-other-day schedule
• Either: you tried to reduce your steroid dose in the last 12 months but were unable to, and your dose has been stable for at least 6 weeks before joining — OR: you have not tried to reduce your dose in the last 12 months, and your dose has been stable for at least 3 months before joining

Who may not be able to join:

• You have previously taken part in a double-blind study of a supplement called DHEA at Stanford University
• You are currently taking medications that suppress the immune system
• You are currently taking part in another clinical study
• You have taken any experimental medication within the past 30 days (or longer, depending on the medication)
• You have received certain treatments — including hormones, immune system medications, or chemotherapy drugs — within the past 3 months (confirm with trial site for full list)
• Your dose of anti-inflammatory drugs or a medication called hydroxychloroquine has changed within the past month
• You have a known allergy or sensitivity to DHEA or any of its ingredients, including cornstarch, lactose, or magnesium stearate
• You have a condition that would make it difficult for you to follow the study requirements reliably
• You have a history of breast cancer or cancer of the reproductive organs
• You are pregnant (a negative pregnancy test within 2 weeks before joining is required)
• You are able to become pregnant but are not using a reliable form of contraception
• You are taking a contraceptive pill that contains oestrogen

Important: Always verify eligibility with the trial site directly before applying.