NCT00182806

Who might be able to join this trial:

• You have been diagnosed with non-small cell lung cancer (NSCLC), confirmed by a tissue or cell sample test.
• Your cancer is either stage IIIA or IIIB and has gotten worse/progressed, OR it is stage IV and you have already tried one chemotherapy treatment that included a platinum-based drug (including treatments given after surgery).
• Your cancer can be seen and measured (or at least detected) on a scan.
• If your cancer has spread to the brain, you have already received treatment for it, you have no brain-related symptoms, and the cancer has also spread somewhere else outside the brain.
• You are 18 years of age or older.
• You are generally well enough to carry out daily activities with little or no limitation (confirm with trial site).
• Your doctors expect you to live for more than 12 weeks.
• Your blood cell counts (white blood cells, neutrophils, and platelets) are at healthy enough levels (confirm with trial site).
• Your liver is working well enough, based on blood test results (confirm with trial site).
• Your kidneys are working well enough, based on blood test results (confirm with trial site).
• If you are able to have children, you must be willing to use effective barrier contraception (such as condoms) during treatment and for 3 months after finishing.

Who may not be able to join:

• You are pregnant or breastfeeding, or your pregnancy test comes back positive.
• You have unstable chest pain (unstable angina), heart failure, or had a heart attack within the last 3 months.
• You have a serious, life-threatening heart rhythm problem that requires ongoing treatment.
• You have a seizure disorder that is not well controlled.
• You have diabetes that is not well controlled.
• You have an active infection that requires treatment with medication taken throughout your body (such as IV or oral antibiotics).
• You have had another type of cancer in the past 5 years, except for certain skin cancers or a very early-stage cervical condition.
• You have received chemotherapy within the last 3 weeks, or radiotherapy within the last 4 weeks.
• You have previously been treated with a chemotherapy drug called gemcitabine.
• You have had more than one chemotherapy treatment for your lung cancer (not counting a drug called gefitinib).
• You are currently receiving any other chemotherapy or radiation therapy.
• You took part in another clinical trial using an experimental treatment within the last month.
• You are currently taking any other experimental treatments.
• You have any other serious or unstable medical condition.

Important: Always verify eligibility with the trial site directly before applying.