NCT00189566

Who might be able to join this trial:

• You are over 18 years old
• You have been diagnosed with cancer of the ovary, fallopian tube, or peritoneum, confirmed by a laboratory test on tissue
• Your cancer has spread to the lining of the abdomen, lymph nodes, or other organs
• Your cancer has gotten worse during treatment, or came back within 6 months after your first or second chemotherapy treatment containing platinum
• It has been at least 3 weeks since your last chemotherapy session
• Your cancer can be measured on a scan or tracked using a blood marker called CA-125
• You are reasonably active and able to carry out daily activities (confirm with trial site)
• Doctors expect you to live for at least 12 weeks

Who may not be able to join:

• You have previously received a specific form of paclitaxel chemotherapy given on a weekly schedule
• You are currently taking part in another clinical trial, or have done so in the last 30 days
• You have had a bone marrow transplant using your own cells, or radiation to your abdomen, within the last 5 years
• You have previously had another type of cancer
• You have a history of heart problems, such as heart disease, heart failure, irregular heartbeat, high blood pressure, or significant heart valve problems
• You have existing nerve problems affecting movement or sensation that are more than mild in severity
• You have significant problems with your bone marrow, kidneys, or liver function
• You have a serious active infection, or a blockage in your bowel (full or partial)
• You have had brain tumours that caused symptoms
• You are a woman who could become pregnant and are not using a reliable method of contraception
• You are pregnant or currently breastfeeding
• You have had a serious allergic reaction to paclitaxel, topotecan, carboplatin, or any closely related medicines

Important: Always verify eligibility with the trial site directly before applying.