NCT00436020

Who might be able to join this trial:

• You have been diagnosed with bipolar disorder (type I or II) and are currently going through a major depressive episode.
• You are between 18 and 70 years old.
• Your depressive symptoms have lasted for at least one month and are serious enough to be considered a major depressive episode.
• Your depression has been measured as moderate to severe using a standard rating scale (a score above 20 on the Hamilton Depression Rating Scale).
• You have not started any new antidepressant or other mental health medications, and have not had your current medications increased, in the 4 weeks before joining the study.

Who may not be able to join:

• You have an unstable medical condition, a neurological disorder, any history of seizures, or you are currently pregnant or breastfeeding.
• In the doctor's judgement, your risk of suicide is serious enough that you need immediate electroconvulsive therapy (ECT).
• You currently have a diagnosis of substance abuse or addiction, a personality disorder, or another major mental health condition alongside your bipolar disorder.

Important: Always verify eligibility with the trial site directly before applying.