NCT00470639

Who might be able to join this trial:

• You have been diagnosed with a major depressive episode that has lasted no more than 3 years.
• You have been diagnosed with bipolar disorder type I or type II.
• Your depression has been measured as moderately severe or worse using a standard rating scale (a score of 20 or more on the Montgomery-Asberg Depression Rating Scale).
• You are 18 years of age or older.
• You may or may not currently be taking antidepressant medication.

Who may not be able to join:

• You are unable to give informed consent to participate in the trial.
• You have already tried ECT (electroconvulsive therapy) during your current episode of depression and it did not work.
• You have another significant mental health diagnosis, such as schizophrenia.
• You are considered to be in immediate danger, either physically or mentally, or need very urgent medical treatment due to severe symptoms, psychosis, or a high risk of suicide.
• You currently have, or are dependent on, alcohol or other substances.
• You have a history of a neurological condition (such as epilepsy) or have previously had brain surgery.
• You have any metal in your head, or a pacemaker, cochlear implant, medication pump, or other electronic device in your body.
• You are a woman of childbearing age where pregnancy cannot be ruled out.
• You have a history of your mood suddenly shifting to the opposite extreme (such as from depression to mania) in response to treatments.

⚠️ Important: Always verify eligibility with the trial site directly before applying.