NCT01630525

Who might be able to join this trial:

• You must be older than 60 years of age
• You must have good enough vision (with glasses or contacts if needed) to see clearly with both eyes
• You must be willing and able to sign a consent form agreeing to take part
• You must be covered by French Social Security

If you have early-stage (prodromal) Alzheimer's (Group A):

• You have concerns about your memory
• Your ability to carry out daily tasks is normal or only very slightly affected
• You show a specific pattern of memory difficulties identified through testing (confirm with trial site)
• Your score on a standard memory and thinking test (CDR) is 0.5 or above
• Your memory problems have lasted more than 3 months
• Your overall thinking and reasoning is still largely intact (MMSE score of 24 or above)
• Other possible causes of your memory problems have been ruled out
• You have had a brain scan (MRI) showing little or no significant shrinkage in memory-related brain areas

If you have typical mild to moderate Alzheimer's (Group B):

• You have been formally diagnosed with Alzheimer's disease using standard medical criteria
• Your score on a standard thinking and memory test (MMSE) is 20 or above

If you are a healthy volunteer (Group C):

• You have no significant concerns about your memory or thinking
• Your score on a standard thinking and memory test (MMSE) is 24 or above

Who may not be able to join:

• Anyone with a significant vision problem that cannot be corrected with glasses
• Anyone with eye movement problems or a squint (where the eyes do not align properly)
• Anyone currently being treated for depression
• Anyone who is unable to give their own consent to participate
• Healthy volunteers who have any memory or thinking concerns
• Healthy volunteers whose thinking or memory tests at the first visit suggest any cognitive difficulties

Important: Always verify eligibility with the trial site directly before applying.