NCT02883296

Who might be able to join this trial:

• You are willing and able to participate, and can give written consent
• You have been diagnosed with Crohn's disease, confirmed through medical tests such as blood work, endoscopy, imaging, or clinical assessment
• You have been receiving infliximab or adalimumab (biologics) to treat fistulas near your back passage for at least one year
• You do not currently have a draining seton (a surgical thread used to drain fistulas) in place
• You do not currently have any active symptoms or signs of perianal (near the back passage) disease at the time of joining the trial
• You are already having MRI scans to monitor your perianal Crohn's disease

Who may not be able to join:

• You are under legal guardianship or are not enrolled in a social security/health insurance scheme (confirm with trial site)
• You are unable or unwilling to give informed consent
• You are not currently monitored with MRI scans, or you cannot have an MRI — for example, if you have a pacemaker, implantable defibrillator, cochlear implant, certain surgical clips or metal objects in your body, recently placed implants or bone fixation devices, or a known allergy to gadolinium contrast dye
• You already have surgery for Crohn's disease planned at the time of joining, or you are taking part in another study looking at treatments for perianal fistulas related to Crohn's disease
• You are receiving anti-TNF medication (such as infliximab or adalimumab) specifically for Crohn's disease affecting your digestive tract rather than your perianal area
• You currently have active perianal (near the back passage) disease or lesions

Important: Always verify eligibility with the trial site directly before applying.