Crohn's Disease and Colitis

Clinical trials recruiting in Australia for Crohn's Disease and Colitis, as the public registries list them.

Also called: Colitis; Distal colitis; Pancolitis; Ulcerative proctitis; Colitis gravis; Idiopathic proctocolitis; Inflammatory bowel disease, ulcerative colitis type; UC; Regional enteritis; Regional ileitis; Colitis, granulomatous; Crohn disease; Crohn's enteritis; Enteritis, granulomatous; Enteritis, regional

Follow this condition

Sources: ClinicalTrials.gov, ISRCTN registry, MedlinePlus Checked: 15 October 2026 Not medical advice

At a glance

36 trials recruiting in Australia

6 states or territories with a listed site

1 started recruiting in the last 30 days

635 trials recruiting overseas

15 October 2026 date last checked

Where the trials are

Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.

5 listed sites on this page do not say which state they are in, so the counts above are lower than the real number of sites in some states. The trials themselves are all listed below.

Trials for Crohn's Disease and Colitis

36 of 36 trials shown.

This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.

voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice

Trials not shown here

Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.

Trials overseas

635 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.

These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.

Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas

About Crohn's Disease and Colitis

The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.

What is Crohn's disease? Crohn's disease is a chronic (long-lasting) disease that causes inflammation in your digestive tract. It can affect any part of your digestive tract, which runs from your mouth to your anus. But it usually affects your small intestine and the beginning of your large intestine. Crohn's disease is an inflammatory bowel disease (IBD). Ulcerative colitis and microscopic colitis are other common types of IBD. What causes Crohn's disease? The cause of Crohn's disease is unknown. Researchers think that an autoimmune reaction may be one cause. An autoimmune reaction happens when your immune system attacks healthy cells in your body. Genetics may also play a role, since Crohn's disease can run in families. Stress and eating certain foods don't cause the disease, but they can make your symptoms worse. Who is more likely to develop Crohn's disease? There are certain factors that may raise your risk of Crohn's disease: - Family history of the disease. Having a parent, child, or sibling with the disease puts you at higher risk. - Smoking. This may double your risk of developing Crohn's disease. - Certain medicines, such as antibiotics, birth-control pills, and nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen. These may slightly increase your chance of developing Crohn's. - A high-fat diet. This may also slightly increase your risk of Crohn's. What are the symptoms of Crohn's disease? The symptoms of Crohn's disease can vary, depending where and how severe your inflammation is. The most common symptoms include: - Diarrhea - Cramping and pain in your abdomen - Weight loss Some other possible symptoms are: - Anemia, a condition in which you have fewer red blood cells than normal - Eye redness or pain - Fatigue - Fever - Joint pain or soreness - Nausea or loss of appetite - Skin changes that involve red, tender bumps under the skin Stress and eating certain foods such as carbonated (fizzy) drinks and high-fiber foods may make some people's symptoms worse. What other problems can Crohn's disease cause? Crohn's disease can cause other problems, including: - Intestinal obstruction, a blockage in the intestine - Fistulas, abnormal connections between two parts inside of the body - Abscesses, pus-filled pockets of infection - Anal fissures, small tears in your anus that may cause itching, pain, or bleeding - Ulcers, open sores in your mouth, intestines, anus, or perineum - Malnutrition, when your body does not get the right amount of vitamins, minerals, and nutrients it needs - Inflammation in other areas of your body, such as your joints, eyes, and skin How is Crohn's disease diagnosed? Your health care provider may use many tools to make a diagnosis: - A medical history, which includes asking about your symptoms - A family history - A physical exam, including: - Checking for bloating in your abdomen. - Listening to sounds within your abdomen using a stethoscope. - Tapping on your abdomen to check for tenderness and pain and to see if your liver or spleen is abnormal or enlarged. - Various tests, including: - Blood and stool tests. - A colonoscopy. - An upper GI endoscopy, a procedure in which your provider uses a scope to look inside your mouth, esophagus, stomach, and small intestine. - Diagnostic imaging tests, such as a CT scan or an upper GI series. An upper GI series uses a special liquid called barium and x-rays. Drinking the barium will make your upper GI tract more visible on an x-ray. What are the treatments for Crohn's disease? There is no cure for Crohn's disease, but treatments can decrease inflammation in your intestines, relieve symptoms, and prevent complications. Treatments include medicines, bowel rest, and surgery. No single treatment works for everyone. You and your provider can work together to figure out which treatment is best for you: - Medicines for Crohn's include various medicines that decrease the inflammation. Many of these medicines do this by reducing the activity of your immune system. Certain medicines can also help with symptoms or complications, such as nonsteroidal anti-inflammatory drugs and anti-diarrheal medicines. If your Crohn's causes an infection, you may need antibiotics. - Bowel rest involves drinking only certain liquids or not eating or drinking anything. This allows your intestines to rest. You may need to do this if your Crohn's disease symptoms are severe. You get your nutrients through drinking a liquid, a feeding tube, or an intravenous (IV) tube. You may need to do bowel rest in the hospital, or you may be able to do it at home. It will last for a few days or up to several weeks. - Surgery can treat complications and reduce symptoms when other treatments are not helping enough. The surgery will involve removing a damaged part of your digestive tract to treat: - Fistulas - Bleeding that is life threatening - Intestinal obstructions - Side effects from medicines when they threaten your health - Symptoms when medicines do not improve your condition Changing your diet can help reduce symptoms. Your provider may recommend that you make changes to your diet, such as: - Avoiding carbonated drinks - Avoiding popcorn, vegetable skins, nuts, and other high-fiber foods - Drinking more liquids - Eating smaller meals more often - Keeping a food diary to help identify foods that cause problems In some cases, your provider may ask you to go on a special diet, such as a diet that is: - High calorie - Lactose free - Low fat - Low fiber - Low salt If you are not absorbing enough nutrients, you may need to take nutritional supplements and vitamins. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Ulcerative colitis (UC) is a disease that causes inflammation and sores, called ulcers, in the lining of the rectum and colon. It is one of a group of diseases called inflammatory bowel disease. UC can happen at any age, but it usually starts between the ages of 15 and 30. It tends to run in families. The most common symptoms are pain in the abdomen and blood or pus in diarrhea. Other symptoms may include: - Anemia - Severe tiredness - Weight loss - Loss of appetite - Bleeding from the rectum - Sores on the skin - Joint pain - Growth failure in children About half of people with UC have mild symptoms. Doctors use blood tests, stool tests, colonoscopy or sigmoidoscopy, and imaging tests to diagnose UC. Several types of drugs can help control it. Some people have long periods of remission, when they are free of symptoms. In severe cases, doctors must remove the colon. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

US source; availability in Australia may differ.

Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.

Sources and dates

ClinicalTrials.gov – trial records, statuses and site lists
ISRCTN registry – trial records for studies registered there
MedlinePlus – the About text above, reproduced exactly
ClinicalTrials.gov processing date: 15 October 2026.
This page last checked by Voxsanity: 15 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Questions to ask your doctor

General questions, the same on every condition page. Print this page to take them with you.

Is a clinical trial something I should consider at this point?
What would taking part involve week to week?
What are the risks, and what happens if I change my mind?
Would being in a trial change the care I get now?
Who would I see, and how far would I need to travel?
Are there costs, and is travel or time off work covered?
Can you refer me, or do I contact the trial site myself?

Is a medicine on the PBS?

Search the PBS on the Pharmaceutical Benefits Scheme's own website. Voxsanity does not publish PBS listings.

Where to get support

Crohn's and Colitis Australia is the national body for people with Crohn's disease and ulcerative colitis.

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Crohn's Disease and Colitis

At a glance

Where the trials are

Trials for Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 4 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 1 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 1 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 3 study for people with Crohn's Disease and Colitis

Phase 2 study for people with Crohn's Disease and Colitis

Phase 1 study for people with Crohn's Disease and Colitis

Trials not shown here

Trials overseas

About Crohn's Disease and Colitis

Sources and dates

Tell us which conditions matter to you

Related conditions