Osteoarthritis
Clinical trials recruiting in Australia for Osteoarthritis, as the public registries list them.
Also called: Degenerative joint disease; OA; Osteoarthrosis; Arthritis, degenerative; Arthropathy; Degenerative polyarthritis; Hypertrophic arthritis; Osteoarthritis deformans
At a glance
13 trials recruiting in Australia
4 states or territories with a listed site
0 started recruiting in the last 30 days
918 trials recruiting overseas
11 October 2026 date last checked
Where the trials are
Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.
1 listed site on this page does not say which state it is in, so the counts above are lower than the real number of sites in some states. The trials themselves are all listed below.
Trials for Osteoarthritis
13 of 13 trials shown.
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Not a phased study
Study for people with Osteoarthritis
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Sydney Shoulder & Elbow, NSW, Sydney (NSW) — Terminated
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Zimmer BiometTimelineStarted 1 June 2015 Today 16 October 2026 Estimated completion 1 December 2035NCT02469662 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Osteoarthritis
Where- Northern Hospital, Epping (VIC) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Smith & Nephew, Inc.TimelineStarted 12 February 2022 Today 16 October 2026 Estimated completion 17 April 2026Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.
NCT04848896 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Osteoarthritis
Where- University of Sydney, Sydney — Recruiting
Who can join Age 50 Years and over. Sex Female participants only. Healthy volunteers Accepted.Sponsor Wake Forest UniversityTimelineStarted 21 March 2024 Today 16 October 2026 Estimated completion 31 July 2029NCT05946044 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Osteoarthritis
Where- St John of God Subiaco Hospital, Subiaco (WA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Stryker Australia Pty Ltd.TimelineStarted 22 February 2024 Today 16 October 2026 Estimated completion 1 March 2028NCT06108934 · Checked 11 October 2026
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Not yet recruiting Phase 3
Phase 3 study for people with Osteoarthritis
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Integrant Office, Potts Point (NSW) — this site's status is not stated on the record
Who can join Age 18 Years to 70 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Integrant Pty LtdTimelineStarted 1 November 2026 Today 16 October 2026 Estimated completion 1 August 2027NCT06907121 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Osteoarthritis
Where- Mid North Coast Local Health District, Coffs Harbour (NSW) — Recruiting
- Northern NSW Local Health District, Lismore (NSW) — Recruiting
- University Centre for Rural Health, University of Sydney, Lismore (NSW) — Not yet recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor University of SydneyTimelineStarted 17 September 2025 Today 16 October 2026 Estimated completion 29 February 2028NCT07173335 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Osteoarthritis
Where- Emeritus Research Sydney, Botany (NSW) — Recruiting
- Genesis Research Services, Broadmeadow (NSW) — Recruiting
- Royal North Shore Hospital, St Leonards (NSW) — Recruiting
- University of the Sunshine Coast Clinical Trials, Birtinya, Birtinya (QLD) — Recruiting
- University of the Sunshine Coast Clinical Trials, Morayfield, Morayfield (QLD) — Recruiting
- University of the Sunshine Coast Clinical Trials, Noosa, Noosaville (QLD) — Recruiting
- Momentum Clinical Research Taringa, Taringa (QLD) — Recruiting
- Momentum Clinical Research Wellers Hill, Tarragindi (QLD) — Terminated
- Momentum Clinical Research Sunshine, St Albans (VIC) — Recruiting
Who can join Age 40 Years to 80 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Doron Therapeutics Inc.TimelineStarted 14 October 2025 Today 16 October 2026 Estimated completion 1 April 2027NCT07219771 · Checked 11 October 2026
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Recruiting Phase 1
Phase 1 study for people with Osteoarthritis
Where- Cognivus Research Group, Wahroonga (NSW) — Recruiting
Who can join Age 20 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Avidence TherapeuticsTimelineStarted 22 January 2026 Today 16 October 2026 Estimated completion 1 December 2026NCT07338266 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Osteoarthritis
Where- Emeritus Research Sydney, Botany (NSW) — Recruiting
- Momentum Clinical Research Darlinghurst, Darlinghurst (NSW) — Recruiting
- Kolling Institute, St Leonards (NSW) — Recruiting
- Heart of Australia, Chelmer (QLD) — Recruiting
- Coastal Digestive Health, Maroochydore (QLD) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Novo Nordisk A/STimelineStarted 13 April 2026 Today 16 October 2026 Estimated completion 14 August 2028NCT07481630 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Osteoarthritis
Where- Emeritus Research Sydney, Botany (NSW) — Recruiting
- Momentum Clinical Research Darlinghurst, Darlinghurst (NSW) — Recruiting
- Kolling Institute, St Leonards (NSW) — Recruiting
- Heart of Australia, Chelmer (QLD) — Recruiting
- Coastal Digestive Health, Maroochydore (QLD) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Novo Nordisk A/STimelineStarted 20 April 2026 Today 16 October 2026 Estimated completion 14 August 2028NCT07509307 · Checked 11 October 2026
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Not yet recruiting Phase 1
Phase 1 study for people with Osteoarthritis
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Sydney Pain Management Centre, Wahroonga (NSW) — this site's status is not stated on the record
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Interventional AnalgesiX Inc.TimelineStarted 1 June 2026 Today 16 October 2026 Estimated completion 31 January 2027NCT07520240 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Osteoarthritis
Where- Susan Wakil Health Building, Camperdown (NSW) — Recruiting
- The University of Queensland Therapies Building (84A), Brisbane (QLD) — Not yet recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor University of SydneyTimelineStarted 1 April 2026 Today 16 October 2026 Estimated completion 1 April 2028NCT07532070 · Checked 11 October 2026
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Not yet recruiting Not a phased study
Study for people with Osteoarthritis
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Royal North Shore Hospital, Sydney (NSW) — this site's status is not stated on the record
Who can join Age 40 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Pleryon Therapeutics (Hangzhou) LimitedTimelineStarted 1 August 2026 Today 16 October 2026 Estimated completion 1 June 2027NCT07611708 · Checked 11 October 2026
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voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice
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Trials overseas
918 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
About Osteoarthritis
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
What is osteoarthritis? Osteoarthritis, sometimes called OA, is a type of arthritis that only affects the joints, usually in the hands, knees, hips, neck, and lower back. It's the most common type of arthritis. In a healthy joint, the ends of the bones are covered with a smooth, slippery tissue called cartilage. The cartilage pads the bones and helps them glide easily when you move the joint. With osteoarthritis, the cartilage breaks down and becomes rough. Sometimes, all the cartilage wears away and the bones rub together. Bumps of extra bone called bone spurs may grow in the joint area. There is no cure for osteoarthritis. It usually gets worse slowly. But there's a lot you can do to manage the symptoms. What are the symptoms of osteoarthritis? Osteoarthritis affects people in different ways, and not everyone has pain. The most common symptoms are: - Pain when you move, which often gets better with rest - Stiffness, especially for the first 30 minutes after you get up from resting - Swollen joints, especially after using the joint a lot - Less movement in the joint than normal - A joint that feels loose or unstable What causes osteoarthritis? Researchers aren't sure what causes osteoarthritis. They think that it could be caused by a combination of factors in the body and the environment. Your chance of developing osteoarthritis increases with age. They also know that some people are more likely to develop it than others. Who is more likely to develop osteoarthritis? Things that make you more likely to develop osteoarthritis include: - Aging. Osteoarthritis can happen at any age, but the chance of getting it increases in middle-aged adults and older. After age 50, it is more common in women than in men. - Being overweight. Extra weight puts more stress on your joints. - Having a past injury or surgery on a joint. This is often the cause of osteoarthritis in younger adults. - Doing a lot of activities that overuse the joint. This includes sports with a lot of jumping, twisting, running, or throwing. - Having a joint that doesn't line up correctly. - A family history of osteoarthritis. Some people inherit genetic changes that increase their chance of developing osteoarthritis. How is osteoarthritis diagnosed? There is no specific test for osteoarthritis. To find out if you have osteoarthritis, your provider: - Will ask about your symptoms and medical history - Will do a physical exam - May use x-rays or other imaging tests to look at your joints - May order lab tests to make sure that a different problem isn't causing your symptoms What are the treatments for osteoarthritis? The goal of treating osteoarthritis is to ease your pain, help you move better, and stop it from getting worse. Treatment usually begins with: - Exercises to improve strength, flexibility and balance - Weight loss, if needed, to improve pain, especially in your hips or knees - Braces or shoe inserts (orthotics) that a health care provider fits for you You can buy some pain relievers and arthritis creams without a prescription. They can be helpful, but it's best to talk to your provider about using them. If they don't help enough, your provider may prescribe injections (shots) into the joint or prescription pain relievers. Complementary therapies may help some people. Massage can increase blood flow and bring warmth to the area. Some research shows that acupuncture may help relieve osteoarthritis pain. Simple things like heat and ice can help, too. If none of these treatments help enough, surgery may be an option. You and your provider can decide if it's right for you. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- ClinicalTrials.gov processing date: 18 September 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
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