Rheumatoid Arthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older.
• People who have signed a consent form that has been approved by an ethics review board.
• People who have been identified as a candidate for a first-time or repeat total elbow replacement surgery, due to at least one of the following conditions:
  • Severe elbow joint damage that significantly affects everyday activities.
  • Injury-related damage or bone loss that makes the elbow unstable.
  • A stiff, locked elbow joint (especially when both elbows are affected, for reasons other than active infection).
  • Advanced arthritis (rheumatoid, injury-related, or wear-and-tear) causing severe, disabling pain.
  • Elbow instability or limited movement where the damage to the joint or surrounding tissue is too extensive for standard bone repair.
  • A severe, complex fracture of the elbow joint that cannot be treated with less invasive procedures, including certain fractures of the lower end of the upper arm bone.
• People who are willing and able to attend follow-up appointments as required by the study.
• (For a separate, retrospective part of the study only) People who had a total elbow replacement using the Nexel system between July 2013 and the date the study site began, and whose medical records include pre-surgery details, a physical exam record, the surgical report, and details of the devices used.

Who may not be able to join:

• People who currently have, or have had repeated, infections at or near the surgery site.
• People who currently have a serious infection elsewhere in the body.
• People who have a history of a severe, widespread infection (sepsis).
• People who have paralysis or significant nerve problems affecting the elbow joint.
• People who have significant problems with the function of the hand on the same side as the affected elbow.
• People who have heavy scarring near the surgery site that could prevent proper healing of the surrounding tissue.
• People whose daily activities place heavy stress on a joint implant, such as heavy physical labour, high twisting forces on the arm, or competitive sports.
• People who are currently imprisoned.
• People who are not able to understand what taking part in the study involves.
• People who have a known problem with alcohol or drug misuse.
• People who are not expected to be able to follow the study requirements.
• People who are known to be pregnant.

Important: Always verify eligibility with the trial site directly before applying.