COPD

**Who might be able to join this trial:** - You have been diagnosed with COPD (chronic obstructive pulmonary disease) and have had at least one flare-up (worsening of symptoms) in the past year - Your breathing test results show a specific pattern of airflow limitation, with a ratio of two measurements (FEV1/FVC) at 70...

Who might be able to join this trial: - You are a man or woman aged 40 or older who is willing to sign a consent form before any study activities begin - You have been diagnosed with moderate to severe chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes it hard to breathe - You have a sm...

Who might be able to join this trial: - You are 40 years of age or older - You have been diagnosed with moderate to severe chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes it hard to breathe - You have a smoking history of at least 10 "pack years" (for example, smoking one pack per da...

Who might be able to join this trial: - You have agreed to take part by signing a consent form before the study begins. - You have been diagnosed with chronic obstructive pulmonary disease (COPD) and your breathing test results meet certain specific measurements (confirm with trial site). - You are between 40 and 75 ye...

**Who might be able to join this trial:** - You have been diagnosed with moderate to severe COPD (classified as Stage II or Stage III under standard medical guidelines) - You are a current smoker or ex-smoker with a smoking history of at least 10 "pack years" (for example, smoking one pack a day for 10 years, or two pa...

**Who might be able to join this trial:** - You have been diagnosed with moderate to very severe COPD (a lung condition that makes it hard to breathe), based on recognised international guidelines. - Breathing tests done after using a bronchodilator (an inhaler that opens the airways) show your lung function is below c...

**Who might be able to join this trial:** - You are between 40 and 80 years old - You have been diagnosed with COPD (a long-term lung condition) based on recognised medical guidelines - You are a current or former smoker with at least a 10 pack-year smoking history (for example, smoking one pack a day for 10 years, or...

**Who might be able to join this trial:** - You are a current or past smoker (with a significant smoking history of more than 10 "pack years") or have had long-term exposure to smoke from burning wood, coal, or other solid fuels - You are between 40 and 80 years old - You have been diagnosed with COPD (a chronic lung...

**Who might be able to join this trial:** - Women who cannot become pregnant, are at least 2 years past menopause, or who test negative for pregnancy at the first visit and agree to use reliable birth control throughout the study. - People who have been formally diagnosed with COPD (a chronic lung condition) based on r...

**Who might be able to join this trial:** - People aged 2 years or older at the time of signing the consent form. - People who have received an allogeneic stem cell transplant (a transplant using stem cells from a donor) and have active chronic graft-versus-host disease (cGVHD) — a condition where the donor cells atta...

**Who might be able to join this trial:** - People who have completed the full 52-week treatment period in one of the two related earlier studies (called GB43311 or GB44332) **Who may not be able to join:** - People who withdrew their consent or left the earlier study early before finishing it - People whose study med...

**Who might be able to join this trial:** - People who are between 40 and 75 years of age - People who have been diagnosed with COPD for at least 12 months before the screening visit, and who have elevated levels of a certain type of white blood cell (eosinophils) in their blood at screening - People whose breathing t...

Who might be able to join this trial: - People who are 12 years of age or older at the time of giving consent to participate. - People who have been newly diagnosed with moderate or severe chronic graft-versus-host disease (cGVHD) — a condition that can occur after a stem cell transplant — that requires treatment throu...

**Who might be able to join this trial:** - People aged 40 to 80 years old - People who have been diagnosed with COPD for at least 1 year - People whose lung function test results fall within a specific range, showing moderate-to-severe airflow limitation (confirm exact values with trial site) - People who have been t...

**Who might be able to join this trial:** - People aged between 40 and 80 years old at the time of signing the consent form - People with a higher-than-normal level of a type of white blood cell called eosinophils in their blood - People with a confirmed diagnosis of COPD (a chronic lung condition) for at least 1 year...

**Who might be able to join this trial:** - People aged 39 to 69 years old (inclusive) - Women who are not pregnant or breastfeeding, and who are either unable to have children, or who are willing to use an acceptable form of contraception from the screening stage until 30 days after the last dose of the study treatme...

Who might be able to join this trial: - People who are 40 years of age or older at the time of signing the consent form. - People who have had a confirmed diagnosis of COPD (chronic obstructive pulmonary disease) for at least 12 months before joining. - People whose lung function test results meet specific measurements...

**Who might be able to join this trial:** - You are 18 years old or older (male or female) - You have been diagnosed with asthma - You have been diagnosed with chronic rhinosinusitis with nasal polyps (a condition where growths develop inside the nose and sinuses) - Your asthma and/or sinus condition is not well contro...

**Who might be able to join this trial:** *As a patient:* - People aged 2 years or older who have no active infections may be seen in person at the clinic; however, samples sent in for diagnostic purposes may be accepted at any age. - People who have signs of immune system problems, such as frequent or unusual infecti...

"Who might be able to join this trial: - People who have been diagnosed with COPD (Chronic Obstructive Pulmonary Disease), confirmed through at least one of the following: a doctor's clinical assessment, breathing/lung function test results, or chest imaging results (such as an X-ray or CT scan). Who may not be able t...

Who might be able to join this trial: - People who are currently non-smokers and have smoked less than 10 pack-years in total throughout their lifetime - People who have asthma that is stable and being treated with medication - People between the ages of 12 and 95 years old - People whose lung function test results, ta...

Who might be able to join this trial: - You developed COPD at a younger age, specifically before age 53 - Your breathing test results show severe COPD, meaning your lungs are working at less than 40% of the expected level for someone your age and size - A doctor has officially diagnosed you with COPD Who may not be ab...

Who might be able to join this trial: - People who are currently non-smokers with a limited smoking history (fewer than 10 pack-years total) - People who have asthma that is stable and being treated with medication - People between 10 and 80 years of age - People whose lung function test results, taken after using a st...

Who might be able to join this trial: - People who are 12 years of age or older. - People who have been diagnosed with a long-term and complex condition, such as Spina Bifida, Spinal Cord Injury, Cerebral Palsy, Traumatic Brain Injury, or a similar condition. - People who live independently in the community, rather tha...

Who might be able to join this trial: - People whose lung function test results show a specific pattern of reduced airflow (a ratio of two breathing measurements — FEV1 and FVC — that is less than 0.70), which can indicate a breathing condition such as COPD (confirm with trial site) - People who are willing and able to...

Who might be able to join this trial: - People who have smoked more than 20 pack-years (a measure of long-term smoking history) and have a breathing test result showing reduced airflow, but not severely reduced (this is called early-stage COPD, classified as GOLD 1 or 2). - Smokers with normal breathing test results ma...

**Who might be able to join this trial:** - People who have experienced lung-related symptoms such as cough, tiredness, general feeling of being unwell, fever, unexplained weight loss, shortness of breath, coughing up blood, or chest discomfort. - People who have had an abnormal chest X-ray or CT scan within the past...

"Who might be able to join this trial: - People aged 18 years or older who have been diagnosed with COPD (a lung disease) - People aged 18 years or older who currently smoke or have smoked in the past - People aged 18 years or older who have a family member with a respiratory (breathing-related) disease - People aged 1...

Who might be able to join this trial: - People who are scheduled to have a bronchoscopic lung volume reduction procedure using one-way valves (a procedure where small valves are placed in the airways through a flexible camera scope to reduce the size of damaged areas of the lung). Who may not be able to join: - There...

**Who might be able to join this trial:** *For people with stable COPD:* - Men or women between 18 and 85 years old - People with a confirmed COPD diagnosis, shown either by a specific breathing test result (FEV1/FVC below 70%) or by an existing COPD diagnosis - People who have given written consent to participate fre...

Who might be able to join this trial: - People who have a flare-up of COPD (chronic obstructive pulmonary disease) causing a buildup of carbon dioxide in the blood, shown by specific blood gas test results (confirm with trial site) - People whose breathing rate is 20 breaths per minute or more during the flare-up - Peo...

**Who might be able to join this trial:** - Adults between 18 and 65 years old who have been diagnosed with cough-variant asthma (CVA), meaning they have had a persistent cough for 8 weeks or more as their main symptom, tested positive on a specific breathing test called a methacholine challenge, and have a history of...

Who might be able to join this trial: - People who have been diagnosed with both asthma and COPD (a condition sometimes called "asthma-COPD overlap") - People who have emphysema (a type of lung damage) and a smoking history of more than 15 pack years (a measure of how much someone has smoked over their lifetime) - Peop...

**Who might be able to join this trial:** - People who have a type of emphysema called "heterogeneous emphysema," confirmed by a detailed CT scan showing that the disease is unevenly distributed across at least one area of the lung that would be treated. - People who are 18 years of age or older. - People who are will...

**Who might be able to join this trial:** - You must have been diagnosed with COPD (a lung condition that makes it hard to breathe). - You must be at your usual, stable level of health on the day of the scan — not in the middle of a flare-up or worsening of symptoms. - You must be classified into a COPD category accord...

Who might be able to join this trial: - People who have been clinically diagnosed with Chronic Obstructive Pulmonary Disease (COPD), a long-term lung condition that makes it hard to breathe. - People who are 40 years of age or older. Who may not be able to join: - People who are unable to complete a breathing test cal...

Who might be able to join this trial: - People with a COPD diagnosis that meets standard medical guidelines, where specific breathing test results show the airways are significantly narrowed (confirm with trial site) - People whose COPD is currently stable and not in an active flare-up Who may not be able to join: - P...

**For COPD Patients:** Who might be able to join this trial: - You have been diagnosed with moderate to very severe COPD (known as GOLD stage II, III, or IV) - Your condition is currently stable and not in a period of sudden worsening Who may not be able to join: - You are under 18 years old - You have an allergy or...

Who might be able to join this trial: - People who are over 18 years of age - People who have had ongoing, function-limiting knee pain from osteoarthritis for at least three months, with a pain score above 6 out of 10 on a specific pain scale, whether or not they have had previous knee surgeries - People who have been...

**Who might be able to join this trial:** - People who have been diagnosed with COPD at a severe stage (classified as GOLD C or D) with lung function below a certain level (FEV1 less than 65%) - People who have recently had an episode of serious breathing difficulties with too much carbon dioxide in the blood (a condi...

Who might be able to join this trial: - People diagnosed with severe emphysema where the damage is unevenly spread across the lungs, affecting at least 10% of the total lung tissue or 25% of the target area - People where the difference in lung damage between the treated area and the rest of the lung on the same side i...

**For People with Obstructive Lung Disease:** Who might be able to join this trial: - People who have been diagnosed with an obstructive lung disease - People who have not had a sudden worsening of symptoms or an infection in the past week - People who are between 18 and 65 years old - People who are willing to take p...

Who might be able to join this trial: - People who have been diagnosed with Alpha-1 Antitrypsin Deficiency (a genetic condition that can affect the lungs and liver), including specific genetic types such as PiZZ, PiZNull, and PiSZ, among others. - People who carry the gene associated with Alpha-1 Antitrypsin Deficiency...

**Who might be able to join this trial:** - People who have been diagnosed with moderate-to-severe obstructive sleep apnea (a condition where breathing repeatedly stops during sleep), confirmed by an overnight sleep study showing 20 or more breathing interruptions per hour - People who also have moderate-to-severe COP...

**Who might be able to join this trial:** - People between the ages of 40 and 85 years old - People who have smoked at least 10 pack-years (roughly the equivalent of one pack per day for 10 years) in their lifetime - People who currently smoke or who used to smoke - People who have been diagnosed with COPD based on a s...

**Who might be able to join this trial:** - Adults aged 18 or older who have been admitted to a medical intensive care unit - People with a Glasgow score of 15 (meaning they are fully alert and responsive) - People experiencing sudden breathing difficulties related to COPD (a lung condition) and/or who have obesity, de...

**Who might be able to join this trial:** **Initial screening phase (Phase I):** - People who are over 35 years old - People who have smoked more than 20 pack-years (a measure of long-term smoking history — confirm with trial site if unsure how this is calculated) - People who are currently smoking, or who stopped smo...

**Who might be able to join this trial:** - Adults aged 18 or older - People who currently smoke or used to smoke, with a smoking history of at least 10 pack-years (a measure of how much someone has smoked over their lifetime) - People who have been diagnosed with COPD (a lung condition) based on recognised medical gu...

**Who might be able to join this trial:** - People between 40 and 75 years old. - People who have a smoking history of at least 20 pack-years (a measure of how much a person has smoked over their lifetime — confirm with trial site if unsure how this applies). - People who have not been diagnosed with COPD or asthma. -...

Who might be able to join this trial: - People who are at least 18 years old - People who have access to the internet - People who are fluent in English or French - People who have had low back pain in the past 4 weeks that was bad enough to limit their usual activities or change their daily routine for more than one d...

Who might be able to join this trial: - People between 40 and 75 years of age. - People whose condition is stable and who are taking less than 10mg of prednisone (or a similar steroid medication) per day. - People who have not smoked for at least 4 months before the screening visit and who are willing to remain non-smo...

Who might be able to join this trial: - People who are 18 years of age or older - People who are able and willing to give their consent to take part in the study Who may not be able to join: - People who have atrial fibrillation (an irregular heartbeat condition) - People whose heart rate is fully controlled by a pace...

**Who might be able to join this trial:** - People aged 40 years or older, of any gender - People who are current smokers or ex-smokers with a significant smoking history (at least 10 "pack-years," which is roughly the equivalent of smoking one pack a day for 10 years) - People who have previously been admitted to hosp...

Who might be able to join this trial: - People who have had 2 or more flare-ups of their chronic obstructive pulmonary disease (COPD) in the past 12 months, have a certain breathing test result or emphysema visible on a scan, and have a smoking history of at least 10 pack-years (a measure that combines how much and how...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with COPD (a lung condition) by a doctor, either based on their medical history or a breathing test result - People who are currently in hospital with a suspected flare-up (sudden worsening) of their COPD - People...

**Who might be able to join this trial:** - **Healthy control group (40 people):** People aged 30–55 with no history of smoking, vaping, or cannabis use (fewer than 100 cigarettes in their lifetime), and whose breathing test results are within the normal range, and who score below 10 on a standard airway symptom quest...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with COPD (a lung condition that makes it hard to breathe) - You have never taken part in a pulmonary rehabilitation programme before (a programme designed to help people with lung conditions through exercise and education)...

Who might be able to join this trial: **For people with COPD:** - A person must have a COPD diagnosis confirmed by a breathing test showing a specific airflow ratio (FEV1/FVC) below the normal lower limit after using a bronchodilator - A person's lung function (FEV1) must be above 30% of what is expected for someone o...

**Who might be able to join this trial:** - People who have been diagnosed with a lung disease - People who are willing and able to understand and sign a written consent form **Who may not be able to join:** - People who currently have an active infection - People who currently have active cancer - People whose multip...

**For Healthy Participants** Who might be able to join this trial: - People who are 18 years of age or older - People who are in generally good health Who may not be able to join: - People with a physical or intellectual condition that would make it difficult to understand the study or follow its procedures - People...

**Who might be able to join this trial:** - You have been diagnosed with COPD (a lung condition), as defined by recognized medical guidelines - You have been admitted to hospital due to a flare-up (worsening) of your COPD - You have severe breathing problems, meaning your blood oxygen levels are very low — either alre...

**Who might be able to join this trial:** - People who are willing and able to sign and date a consent form agreeing to take part - People who are willing to follow all study procedures and are available for the full duration of the study - People aged 30 years or older (any gender) - People with breathing test result...

Who might be able to join this trial: - You must be 18 years of age or older - You are scheduled to have surgery to remove part or all of a lung (such as a lobe, segment, or the whole lung) because of cancer or suspected cancer - You are willing to take part in the study and give your agreement to participate - You are...

Who might be able to join this trial: - You are 18 years of age or older - You have recently been diagnosed with a complication called GVHD (a condition where donated cells react against the body after a transplant) and have just started taking steroid medication for it for the first time since your transplant - You re...

**Who might be able to join this trial:** - People aged between 40 and 75 years old - People whose condition is stable and who are taking less than 10mg of prednisone (or a similar steroid medication) per day - People who have not smoked for at least 4 months before the screening visit and who are willing to remain smo...

**Who might be able to join this trial:** - People who are 40 years of age or older - People who used to smoke but no longer do - People who have a smoking history of at least 10 pack-years (roughly equal to smoking one pack per day for 10 years, or an equivalent amount over a different period) - People whose breathing...

**Who might be able to join this trial:** - People aged 40 to 80 years who have smoked at least 10 pack-years (for example, one pack per day for 10 years) and have been diagnosed with COPD based on established medical guidelines. - People whose breathing test results show a specific level of airflow limitation — measu...

Who might be able to join this trial: - People who are 40 years of age or older - People who have been diagnosed with COPD (a lung disease) by a doctor - People whose COPD falls into a moderate-to-very-severe range, based on specific breathing test results (a breathing test showing certain airflow and lung capacity mea...

**Who might be able to join this trial:** - The participants in this trial are **Primary Care Teams** (groups of healthcare staff who work together to care for a group of patients), not individual patients. - The Primary Care Team must be able to operate as a single, separate unit with little risk of the study's metho...

Who might be able to join this trial: - Women who are planning to have IVF or ICSI fertility treatment at Brussels IVF (UZ Brussel) - Women who are scheduled to have a diagnostic hysteroscopy (a camera examination of the inside of the womb) as part of preparing for their fertility treatment Who may not be able to join...

**Who might be able to join this trial:** - People aged 40 years or older - People who have recently received treatment for a COPD flare-up (worsening of symptoms), either in a hospital or through outpatient care - People who have been referred to a pulmonary rehabilitation (lung exercise and education) program - Peopl...

Who might be able to join this trial: **For people with COPD (a long-term lung condition):** - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) - People aged 18 or older **For people without COPD:** - People who have not been diagnosed with COPD - People aged between 18 and 30, or betw...

Who might be able to join this trial: - People who are willing to sign and date a consent form agreeing to take part in the study - People who are willing to take part in the COPD Wellness program - People between 40 and 90 years old - People who speak English or Spanish - People who have been diagnosed with COPD by a...

**Who might be able to join this trial:** - People who have been officially diagnosed with COPD (a long-term lung condition) - People who have had one or more flare-ups (worsening of symptoms requiring extra treatment) in the past year - People who are 18 years of age or older - People who are willing to use health mon...

Who might be able to join this trial: - Adults aged 18 years or older - People who can speak and understand Danish or English well enough to give informed consent Who may not be able to join: - People who do not have a Danish civil registration number, as without this number the trial site cannot arrange free access t...

**Who might be able to join this trial:** - You are in hospital mainly because of a serious sudden worsening of COPD (Chronic Obstructive Pulmonary Disease). - You have been diagnosed with COPD according to recognised medical guidelines (GOLD 2018 definition). - A breathing test done within the last 5 years showed that...

**Who might be able to join this trial:** - People over 18 years old who have a wound with an unpleasant smell that causes noticeable discomfort (rated more than 4 out of 10 by the patient) - People whose wound is expected to take more than 14 days to heal, based on a doctor's assessment - People who are covered by the...

**Who might be able to join this trial:** - People aged 40 or older, of any gender - People who have been diagnosed with COPD, defined as having smoked more than 10 pack-years and either having reduced lung function on breathing tests or showing signs of emphysema on a chest CT scan (confirm with trial site for virtua...

Who might be able to join this trial: - People who are over 40 years of age - People where an EMT or Paramedic suspects they are having a flare-up of COPD (a lung condition) - People where COPD has been confirmed as a suspected diagnosis Who may not be able to join: - People whose breathing difficulties are caused by...

**Who might be able to join this trial:** - People diagnosed with moderate-to-severe COPD (classified as GOLD class 2 or 3) - People whose lung function test results (specifically how much air can be forcefully exhaled in one second) fall between 30% and 70% of what would normally be expected for someone of their age a...

Who might be able to join this trial: - People aged between 40 and 75 years old - People who have given written consent to take part - People diagnosed with severe emphysema that mainly affects the upper parts of both lungs, at an advanced stage (classified as GOLD stage 3 or 4) - People whose lung scans (taken within...

Who might be able to join this trial: - People who have been diagnosed with COPD (a long-term lung condition), confirmed by a specific breathing test showing reduced airflow that does not improve with an inhaler - People who have ongoing breathing difficulties due to low oxygen levels in the blood, even when resting an...

**Who might be able to join this trial:** *All participants must meet these general criteria:* - You must be able to understand what the study involves and what it is trying to achieve - You must be able to lie still inside an MRI scanner on your back for the full length of the scans - You must be able to give written...

**Who might be able to join this trial:** - People who have been diagnosed with stage 4 (the most severe stage, also called Group D) COPD, based on GOLD guidelines - People who are 18 years of age or older - People who have access to a computer, tablet, or phone with video capability - People who have an internet conne...

**Who might be able to join this trial:** *For people with COPD:* - People with COPD between the ages of 18 and 77, with a mild to moderate-severe disease stage (GOLD Stage 1, 2, or 3), who are already having a bronchoscopy (a camera procedure into the airways) for a medical reason - People with COPD between the ages...

**Who might be able to join this trial:** - People who are able and willing to give their consent to take part in the trial. - People who have been diagnosed with COPD and have been taking azithromycin (an antibiotic) regularly for at least 3 months to help prevent COPD flare-ups. - People who have a self-reported smo...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who can speak, read, and write Dutch or English - People with normal lung function test results — specifically, a FEV1/FVC ratio above 0.70 and FEV1 at or above 80% of the expected value (for certain parts of the trial only — confirm wi...

**Who might be able to join this trial:** - People aged between 40 and 75 years old - People who have been diagnosed with COPD, with breathing test results showing a specific level of airflow limitation and reduced lung function (confirm specific test values with the trial site) - People whose COPD symptoms score at a...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who currently have breathing symptoms such as shortness of breath, cough, or mucus/phlegm production - People who have had breathing tests (spirometry) showing a type of airflow blockage that does not fully reverse with an inhaler, and/o...

Who might be able to join this trial: - People experiencing a sudden worsening of their COPD symptoms that goes beyond their normal day-to-day changes, and that has required a change in their medication. - People whose blood tests show a mild-to-moderate build-up of carbon dioxide in the blood, with specific measuremen...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who received a stem cell transplant from a donor between 90 and 180 days before enrolling in the trial - People who are able to understand and are willing to give their informed consent to pa...

Who might be able to join this trial: - You are 18 years old or older and have been diagnosed with COPD (a lung condition) for at least 1 year - Your COPD has been stable, meaning you have not had a sudden worsening of symptoms in the last 30 days and have not been hospitalised for any reason in the last 3 months - You...

**Who might be able to join this trial:** **Cohort A** (diagnosed with Bronchiolitis Obliterans Syndrome, or BOS, after a stem cell/bone marrow transplant): - A person must have a confirmed diagnosis of BOS after a blood stem cell transplant, based on specific breathing test results that meet either the standard or "...

**Who might be able to join this trial:** - People who are 40 years of age or older - People who have read, understood, and signed a consent form agreeing to take part - People diagnosed with moderate-to-very-severe COPD (a specific lung function measurement below 60% of what is expected, and a symptom score of 10 or m...

Who might be able to join this trial: - You have been diagnosed with moderate to very severe COPD (a serious lung condition), based on specific international guidelines from 2020 - Your COPD has been stable, meaning you have not had a flare-up or worsening of symptoms for at least 30 days - You are male - You are not o...

**Who might be able to join this trial:** - Adults aged between 18 and 55 years old - People who have documented brain or nervous system damage caused by a closed head injury (a head injury that did not break the skull), where current standard treatments are unlikely to help further - People whose level of recovery fal...

**Who might be able to join this trial:** - You are a non-smoker - You are over 40 years old - You have been diagnosed with moderate-to-severe COPD that has been stable (no flare-ups) for more than 6 weeks, confirmed by specific breathing test results (confirm with trial site) **Who may not be able to join:** - You ar...

Who might be able to join this trial: - People who have previously been diagnosed with an airways disease, according to European Respiratory Society guidelines. - People who have never smoked, or who used to smoke but no longer do. - People aged between 18 and 65 years old, male or female. - People who are able to give...

**Who might be able to join this trial:** - People who have been clinically diagnosed with chronic graft-versus-host disease (cGVHD) — a condition that can occur after a stem cell or bone marrow transplant — with at least one recognised sign or symptom of the condition (a formal NIH classification is not required) - I...

**Who might be able to join this trial:** - People who are over 18 years old - People who received a double lung transplant at least 12 months before joining the study - People who have been diagnosed with a specific type of chronic lung transplant complication called CLAD-BOS, where breathing test results (measuring...

Who might be able to join this trial: - People who are 60 years of age or older - People who are able to carry out everyday tasks on their own (such as dressing, eating, and moving around) - People with COPD who have noticeable symptoms (measured by specific breathing questionnaires) or who have not been regularly acti...

Who might be able to join this trial: - People who are 40 years of age or older. - People who have smoked at least 10 pack-years (for example, one pack per day for 10 years, or two packs per day for 5 years). - People who have been recently diagnosed with chronic obstructive pulmonary disease (COPD), a lung condition t...

**Who might be able to join this trial:** - People who have been diagnosed with chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes breathing difficult - People who are currently experiencing a sudden worsening of their COPD where carbon dioxide has built up in the blood and the blood ha...

**Who might be able to join this trial:** - People aged 40 to 75 years old at the time of joining the trial - People who have a confirmed diagnosis of COPD, with breathing test results showing a specific level of airflow limitation and reduced lung function (confirm with trial site for exact test values) - People with...

**Who might be able to join this trial:** - You are an adult who has been admitted to the emergency department with a flare-up of COPD (a lung condition that makes breathing difficult) - You are able to understand the study information and agree to take part - You are covered by social security (health insurance/social...

**Who might be able to join this trial:** - People who have a documented diagnosis of a complicated-mild, moderate, or severe traumatic brain injury (TBI), confirmed through records such as emergency services reports, hospital records, or doctor's notes, and who required a stay in an inpatient rehabilitation unit - Peo...

**Who might be able to join this trial:** - People aged 18 or older - People diagnosed with severe emphysema who have a certain number of treatable airway areas in one lung, as measured by a specialised CT scan - People who have not smoked for at least 2 months before joining, and who are willing to remain smoke-free...

Who might be able to join this trial: - People who have been chosen by their doctor to receive a treatment involving small one-way valves placed inside the airways (called endobronchial valves) - People who have signed a consent form agreeing to take part in the trial Who may not be able to join: - People who have a n...

Who might be able to join this trial: **General asthma group:** - Adults aged 18 to 80 who have been diagnosed with asthma (with or without nasal polyps) of any severity level, based on standard diagnostic guidelines. - People who are already being followed up as part of the existing MEGA asthma study cohort. - People...

**Who might be able to join this trial:** - Men and women (who are not pregnant) between 20 and 65 years old who have had ongoing low back pain for at least one year - People who have already tried non-surgical treatments following standard guidelines — including self-management, exercise, and physical therapy — witho...

**Who might be able to join this trial:** - People who are able to give their informed consent and take part in the study - People aged between 35 and 80 years old at the time of signing the consent form - People who have emphysema (either evenly spread or unevenly spread across the lungs) confirmed on a CT scan taken...

Who might be able to join this trial: - People who have been admitted to hospital with a flare-up of COPD (a lung condition often caused by smoking) as their main diagnosis - People who have a smoking history of at least 10 pack years (this is a measure of how much someone has smoked over time — confirm with trial site...

**Who might be able to join this trial:** - People who have been diagnosed with moderate-to-severe COPD (a serious lung condition), confirmed by specific breathing test results meeting GOLD Grade III or IV standards - People who are older than 40 years of age - People whose COPD has been stable for more than 4 weeks -...

Who might be able to join this trial: - People aged between 18 and 75 years old - People who have been diagnosed with COPD (a long-term lung condition) based on recognised international medical guidelines - People who experience breathlessness during physical activity - People whose condition has been stable, with no i...

**Who might be able to join this trial:** **For people with COPD:** - People who have been diagnosed with Group C or D COPD based on the GOLD staging system (a standard system doctors use to classify how severe COPD is) - People who have been taking the same COPD medications without any changes for at least the past 4...

**Who might be able to join this trial:** **For people with COPD:** - People who have been diagnosed with Stage 2 or Stage 3 COPD, based on guidelines set by the American Thoracic Society and European Respiratory Society - People who have been taking the same medications without any changes for at least the past 4 wee...

**Who might be able to join this trial:** - People who are willing and able to sign a written consent form before any study-related screening takes place - People who are 18 years of age or older at the time of signing consent - People who have previously received a stem cell transplant (using bone marrow, blood stem...

Who might be able to join this trial: - Adults aged 18 years or older - People admitted to hospital for a worsening of COPD (Chronic Obstructive Pulmonary Disease) who already have a confirmed COPD diagnosis - People who live in Aalborg Municipality - People who are able to give their informed consent to participate -...

Who might be able to join this trial: - You were recently discharged from UHN hospital after a flare-up of COPD (a sudden worsening of symptoms), and have been referred to either a Virtual Pulmonary Rehabilitation program or Remote Clinical Monitoring at Toronto Grace Health Centre Who may not be able to join: - Your...

Who might be able to join this trial: - People who have been diagnosed with asthma by a doctor and are currently taking regular asthma medication to manage it - People whose asthma is not well-controlled, meaning their asthma control test (ACT) score is below 20, or they have had at least one asthma flare-up in the pas...

Who might be able to join this trial: - People who are under 55 years old, of any gender - People who have COPD (a lung condition that makes it hard to breathe) and are already scheduled to have a bronchoscopic biopsy (a procedure where a small sample of lung tissue is taken using a thin, flexible tube passed through t...

**Who might be able to join this trial:** - People who have been diagnosed with COPD, classified in groups A, B, or E according to a standard medical assessment system called GOLD - People who are able to walk and move around on their own - People who do not have any health reasons that would prevent them from doing ex...

Who might be able to join this trial: - People who have been diagnosed with COPD (a lung condition) for at least 1 year - People who have been hospitalised for at least 3 days - People who are willing to take part voluntarily Who may not be able to join: - People who are under 18 years old - People who are over 85 yea...

**Who might be able to join this trial:** - Your doctor has decided you are a suitable candidate for a lung procedure using a device called the Zephyr Valve, following Japanese medical guidelines - You have completed a breathing/lung exercise rehabilitation programme within the last 6 months - You have not smoked for...

**Who might be able to join this trial:** - People aged 40 or older (men and women) - People who have a history of smoking at least 10 pack-years (a measure of lifetime smoking amount — confirm with trial site if unsure) - People who stopped smoking at least 6 months ago - People whose breathing test results show a spe...

Who might be able to join this trial: - People whose lung function test (a breathing test called FEV1) shows a result between 30% and 85% of the expected normal value, measured after using a reliever inhaler - People who are already receiving the best available standard treatment for their lung condition, following rec...

Who might be able to join this trial: - People who are 40 years of age or older - People who have been admitted to hospital for a flare-up of their COPD (chronic obstructive pulmonary disease) and have recently been discharged from hospital care, including from virtual ward support (the hospital stay must have lasted a...

Who might be able to join this trial: - You have been diagnosed with chronic obstructive pulmonary disease (COPD) using standard diagnostic guidelines - You are between 40 and 85 years old (inclusive) - Your body mass index (BMI) is 35 or below - Your lung function test results fall within a specific range showing mode...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes breathing difficult - People who are enrolled in a breathing and physical rehabilitation program at the Clinique de la Mitterie...

**Who might be able to join this trial:** - People who are 40 years of age or older - People who have been told by a doctor that they have COPD (a lung condition that makes it hard to breathe) - People whose breathing test results confirm a specific type of airway blockage, measured using a lung function test called sp...

**Who might be able to join this trial:** - People who have been diagnosed with stable COPD, based on the GOLD 2023 guidelines - People aged 40 years or older - People whose breathing test results show a specific pattern of airflow limitation (a post-bronchodilator FEV1/FVC ratio below 70% or below the lower limit of n...

Who might be able to join this trial: - People who are 18 years old or older - People who are currently experiencing breathing or respiratory symptoms - People who complete a questionnaire called the UCAP-Q and receive a score showing at least a 6% chance of having asthma or COPD - People who have signed a written cons...

Who might be able to join this trial: - People who have been diagnosed with COPD (a lung condition) and are living at home - People whose lung function test results (a specific breathing measurement taken after using a puffer) fall below the normal range for their age and body size Who may not be able to join: - Peopl...

**Who might be able to join this trial:** - People aged 40 or older. - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) — a long-term lung condition that makes it hard to breathe — based on internationally recognised guidelines. - People whose COPD is classified as more severe (based on...

**Who might be able to join this trial:** - People who have severe or very severe COPD (classified as GOLD stage 3 or 4) - People who still experience significant breathlessness even after receiving the best available standard treatment - People whose breathlessness is rated at level 3 or higher on a standard scale cal...

Who might be able to join this trial: - People who have been diagnosed with a specific stage of COPD (called GOLD B), meaning they have had no more than one flare-up (worsening of symptoms) in the year before joining the study - People with this stage of COPD who have previously been treated with one or more types of i...

**Who might be able to join this trial:** - You are a woman who has not yet reached menopause, aged between 18 and 50 years - You have a current vaginal yeast infection caused by Candida (confirmed by a lab test within 24–48 hours of your symptoms starting, and before any treatment was started) - You have had at least...

**Who might be able to join this trial:** - People aged 40 to 80 years old, of any sex or race - People who have been diagnosed with COPD according to established international guidelines - People whose breathing test results show a specific pattern of airflow limitation after using a bronchodilator (a lung-opening me...

**Who might be able to join this trial:** *For people with COPD:* - You are over 40 years old - You have been diagnosed with COPD and your condition is currently stable - You are able to follow instructions and participate in the tests required by the study - You do not have any heart, bone/joint, or nerve-related con...

Who might be able to join this trial: - People who have been diagnosed with COPD (a lung condition), confirmed by a breathing test called spirometry - People who are adults (18 years or older) - People who speak Italian - People who are able to complete the required tests involved in the study - People who have given t...

Who might be able to join this trial: - You are between 40 and 70 years old and have been diagnosed with COPD (a long-term lung condition that makes it hard to breathe) based on recognised 2024 guidelines Who may not be able to join: - You have a known allergy condition or allergic disease - You have another long-term...

Who might be able to join this trial: - People who are at least 20 years old - People who have been diagnosed with COPD and have not had an infection or sudden worsening of symptoms in the past four weeks - People who are able to participate in and complete the tests and measurements required by the study Who may not...

**Who might be able to join this trial:** - People over 18 years of age who have been diagnosed with COPD (a long-term lung condition) according to established medical guidelines, and whose lung function has been measured within the last 12 months while their condition was stable - People who have been admitted to hosp...

**Who might be able to join this trial:** - You are a male aged between 55 and 60 years old with a diagnosis of mild to moderate COPD (Grade I or Grade II) - You are in a stable condition, both physically and medically, at the time of joining the study - Your body weight is in a healthy range, with a Body Mass Index (B...

**Who might be able to join this trial:** - You are being seen regularly as an outpatient for a long-term lung condition called COPD (chronic obstructive pulmonary disease), your condition is currently stable, and a CT scan has shown a specific type of lung damage called emphysema (air sac destruction in certain patter...

Who might be able to join this trial: - People aged 40 to 79 years (both men and women) - People who have been diagnosed with COPD at a mild to moderately severe level (known as GOLD stage I to III) - People with a breathlessness score ranging from none to quite severe on a standard scale (mMRC score of 0 to 3) - Peopl...

Who might be able to join this trial: - People who are able to give their informed consent to participate - People aged 18 years or older - People who have been diagnosed with COPD (chronic obstructive pulmonary disease) - People who are able to walk around without help from another person or a mobility aid - People wh...

**Who might be able to join this trial:** - People who have been diagnosed with COPD (Chronic Obstructive Pulmonary Disease) and are willing to take part in the study **Who may not be able to join:** - People who have not been diagnosed with COPD - People who are not willing to take part in the study **Important: Alw...

**Who might be able to join this trial:** - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) and also have at least one heart or blood vessel condition, such as heart failure, a buildup of fatty deposits in the arteries, an irregular heartbeat (atrial fibrillation), or a serious heart va...

Who might be able to join this trial: - Adults aged 18 or older who have been admitted to a hospital ward for a flare-up (sudden worsening) of COPD (chronic obstructive pulmonary disease) - People enrolled in the trial within 72 hours of being admitted to hospital - People who are able to give written consent to partic...

Who might be able to join this trial: **Patients:** - People who are 18 years of age or older - People who have a confirmed COPD diagnosis, supported by breathing tests or imaging scans showing lung changes - People who score 8 or higher on a standard depression symptom questionnaire (called the PHQ-8) at the start of...

**Who might be able to join this trial:** - People aged 40 years or older - People who currently smoke or used to smoke, with a history of at least 10 pack-years of cigarette smoking (this is a measure of how much a person has smoked over time — confirm with trial site if unsure how this applies) - People who have been...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of joining the trial. - People who are planning to receive a stem cell transplant from a donor (called an allogeneic transplant) for one of the following blood cancers: certain types of acute or chronic leukemia with very f...

Who might be able to join this trial: - People who have received a stem cell transplant from a donor and developed moderate to severe chronic graft-versus-host disease (cGVHD) — a condition where the donor cells attack the recipient's body — that requires treatment with immune-suppressing medicines. - People who have b...

**Who might be able to join this trial:** - People who are willing and able to give their informed consent to take part in the study - People who have been referred for pulmonary rehabilitation (a structured breathing and exercise programme) at University Hospital Limerick (UHL) - People who have a confirmed diagnosis...

Who might be able to join this trial: - People aged 40 years or older - People who have been diagnosed with COPD, recorded in their medical file, and whose condition falls into GOLD category B or E — these categories are based on symptom scores and how often flare-ups (exacerbations) have occurred, with or without a ho...

Who might be able to join this trial: - People who have been diagnosed with COPD, classified in groups A, B, or E according to the GOLD assessment system - People who are able to walk and move around on their own - People who have no medical reasons preventing them from doing exercise Who may not be able to join: - Pe...

Who might be able to join this trial: - People who have been diagnosed with a serious, advanced illness such as late-stage cancer or severe chronic lung disease - People whose illness is at an advanced stage and whose life expectancy is estimated to be around 12 months or less - People who are already receiving ongoing...

**Who might be able to join this trial:** - You must be a caregiver for a family member who has been diagnosed with COPD (a chronic lung disease). - You must be 18 years old or older. - The person you care for must currently be in a stable condition, meaning they have not had a flare-up or worsening of their COPD in th...

**Who might be able to join this trial:** **For people with COPD:** - Adults aged 30 to 80 years old who have been diagnosed with COPD according to 2023 international guidelines, confirmed by a breathing test showing reduced airflow even after using a bronchodilator (airway-opening) medication - People whose COPD rang...

**Who might be able to join this trial:** - Adults between 18 and 65 years old who are scheduled for a planned (non-emergency) gallbladder removal surgery using keyhole (laparoscopic) techniques under general anaesthesia - People who have been assessed by an anaesthesiologist as being in generally good to moderate over...

Who might be able to join this trial: - Adults aged 18 or older. - People who have a performance status score of 60% or higher on the Karnofsky scale, which means they are able to care for themselves and carry out some normal activities (confirm with trial site). - People who have been diagnosed with chronic graft-vers...

**Who might be able to join this trial:** - You have received a stem cell (bone marrow) transplant from a donor (not your own cells) - You are aged 12 or older - You have been diagnosed with chronic Graft-versus-Host Disease (cGVHD) — a condition where the donor cells attack your body — and need a new treatment after...

**Who might be able to join this trial:** - You have been diagnosed with asthma by a doctor (following standard medical guidelines) and have been receiving treatment for it for at least 3 years - You are 18 years of age or older and receive your asthma care on an outpatient basis (not in a hospital) - Your asthma is n...

**Who might be able to join this trial:** This trial has three separate groups. Criteria differ depending on which group a person may belong to: **PRISm group (a specific lung function pattern):** - People who are older than 40 years of age - People who have been diagnosed with PRISm (a specific pattern seen on breat...

Who might be able to join this trial: - People who currently smoke or used to smoke, with a significant smoking history of more than 30 pack-years (a measure of how much someone has smoked over their lifetime), including former smokers who quit more than 15 years ago - People who have been diagnosed with a lung conditi...

Who might be able to join this trial: - You are between 50 and 80 years old - You have been diagnosed with COPD (a lung condition) - You do not follow a vegetarian or vegan diet - You are willing to eat the aronia berry (also called black chokeberry) provided by the trial - You are a non-smoker - You are willing to sig...

Who might be able to join this trial: - People who are over 18 years old - People who are covered by a social security scheme - People who have been diagnosed with COPD (chronic obstructive pulmonary disease), at any stage - People who have been referred to a pulmonary rehabilitation program - People who have completed...

Who might be able to join this trial: - People who have been diagnosed with COPD (a long-term lung condition) for at least 1 year - People whose COPD has been confirmed by breathing tests as being at a severe or very severe stage (known as GOLD stage III or IV) - People who are currently in hospital due to a sudden wor...

Who might be able to join this trial: - You have moderate to severe COPD (a serious lung condition) and your doctor has recommended starting a specific triple inhaler treatment called BGF, following local prescribing guidelines - You are already taking part in a related single-arm study (a type of study where all parti...

**Who might be able to join this trial:** - Adults aged 18 years or older, of any gender - Women at any stage of menopause — pre-menopausal, peri-menopausal, or post-menopausal — are all eligible to take part - People who are willing and able to agree to take part by signing a consent form - Healthy participants who ha...

Who might be able to join this trial: - People who are willing to sign a written consent form agreeing to take part. - People who have been diagnosed with pre-COPD or COPD (any stage from I to IV) based on the 2023 GOLD guidelines. - People who have been taking part in pulmonary rehabilitation therapy (a structured bre...

Who might be able to join this trial: - People who are able to sign an informed consent form agreeing to take part in the study. - People who are able to complete a specific breathing test (measuring how much air can be forced out of the lungs in one second) that meets recognised international standards. - People who a...

**Who might be able to join this trial:** - People who are currently taking five or more medications, including prescription drugs, over-the-counter medicines, supplements, natural health products, cannabis products, or recreational drugs - People who are taking blood pressure or depression medications, even if the to...

Who might be able to join this trial: - People who are over 40 years old - People who have been diagnosed with COPD (a lung condition affecting breathing) according to standard medical guidelines, and whose condition is currently stable, meaning no flare-ups in the past month - People who are already enrolled in a pulm...

Who might be able to join this trial: - People who have had a confirmed diagnosis of COPD (a chronic lung condition) for at least 6 months - People who are admitted to the chest clinic - People who have no communication difficulties - People who have voluntarily agreed to take part in the study Who may not be able to...

Who might be able to join this trial: - People who are female or male - People who are 50 years of age or older - People with COPD who are seeking urgent medical care due to a sudden worsening of their condition, where symptoms such as shortness of breath, cough, and/or mucus have gotten worse over less than 14 days, p...

Who might be able to join this trial: - People who have been diagnosed with moderate (Grade II) or severe (Grade III) COPD (a lung condition that makes breathing difficult) for at least one year. - People whose COPD is currently stable and not in an active flare-up. Who may not be able to join: - People who have any e...

**Who might be able to join this trial:** - You must be a Veteran (people of all genders, races, and ethnicities are welcome) - You must have breathing test results that show a specific pattern of airflow limitation (a ratio called FEV1/FVC below 0.7, and a lung capacity score between 30% and 80% of what is expected fo...

**Who might be able to join this trial:** - Adults between the ages of 21 and 100, of any sex or racial/ethnic background, who are able to read and sign consent forms in English or Spanish. - People who have been diagnosed with COPD (a chronic lung condition that makes breathing difficult) according to internationally...

**Who might be able to join this trial:** - You are 18 years of age or older (male or female). - A lung specialist has determined you need a bronchoscopy (a procedure to look inside the airways) for a reason such as follow-up care, investigating a lung nodule, coughing up blood, persistent cough, mucus production, rec...

**Who might be able to join this trial:** - You have been diagnosed with COPD that has been rated as a moderate to very severe level (levels 2–4) - Your COPD has been stable, with no significant worsening, for at least the past three months - You have not taken part in any rehabilitation program in the last six months...

**Who might be able to join this trial:** - People aged 18 or older - People who have been confirmed through tissue or cell testing to have a specific type of advanced lung cancer called squamous non-small cell lung cancer, at stage IIIB or IV - People who have been diagnosed with stable moderate to severe chronic obst...

Who might be able to join this trial: - People who have been diagnosed with a chronic lung condition, such as COPD, pulmonary emphysema, pulmonary fibrosis, asthma, or another lung disease, and are being considered for a pulmonary (lung) rehabilitation program. - People who have been diagnosed with a heart condition —...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of COPD, shown through breathing tests (a specific ratio of less than 0.7 on lung function testing after using an inhaler) and a smoking history of more than 10 pack-years - People who are currently taking part in a pulmonary rehabilitat...

**Who might be able to join this trial:** - People aged 18 or older (any sex) who have a confirmed diagnosis of COPD based on 2024 GOLD guidelines, which includes a history of exposure to risk factors (such as smoking) and breathing test results showing airflow limitation, along with a symptom score of 10 or higher on...

**Who might be able to join this trial:** - Adults aged 18 or older who have a flare-up of COPD (a lung disease that makes breathing difficult) along with breathing failure, and whose heart scan (echocardiogram) shows high blood pressure in the arteries of the lungs (with a specific pressure reading above 20 mmHg) **W...

Who might be able to join this trial: - People aged 40 or older who have been diagnosed with chronic obstructive pulmonary disease (COPD), or people aged 18 or older who have been diagnosed with asthma or bronchiectasis. - People whose main reason for being admitted to hospital was a flare-up of COPD, asthma that was d...

Who might be able to join this trial: - People aged 40 or older who currently smoke or used to smoke, with a smoking history of at least 10 pack-years (roughly 10 years of smoking one pack per day, or an equivalent amount) - People who have been diagnosed with moderate, severe, or very severe COPD, based on specific br...

Who might be able to join this trial: - People who have been diagnosed with COPD (a chronic lung disease) - People whose lung function test results show a specific breathing pattern, where the ratio of two measurements (FEV1/FVC) is less than 0.80 after using a bronchodilator (a medication that opens the airways) - Peo...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are not pregnant - People who are not currently in prison or jail - People with advanced kidney disease where the kidneys are working at a reduced level, specifically with a kidney function score (eGFR) between 15 and 29 mL/min/1.73m² **W...

**Who might be able to join this trial:** - People who are over 40 years of age, of any sex - People with a body mass index (a measure of body weight relative to height) above 18.5 - People who have been diagnosed with Chronic Obstructive Pulmonary Disease (COPD) — a long-term lung condition — and whose condition is cu...

Who might be able to join this trial: - People who have been diagnosed with COPD (chronic obstructive pulmonary disease) - People aged 40 years or older, male or female - People who currently smoke or used to smoke, with a history of at least 20 pack-years (for example, one pack per day for 20 years, or two packs per d...

**Who might be able to join this trial:** - You have a traumatic spinal cord injury that is either fully affecting both movement and sensation, or affecting only movement but not sensation - Your spinal cord injury is located in a specific region of your neck or mid-back (between levels C-4 and T-10) (confirm with tri...

**Who might be able to join this trial:** - People who are at least 12 years old at the time of signing the consent form. - People who are able to understand and are willing to sign a written consent form; for those aged 12 to 17, a parent or guardian must also provide consent. - People of Chinese background who have...

Who might be able to join this trial: - People who are 40 years of age or older - People who have been diagnosed with COPD by a doctor - People who live in a rural area, as defined by Rural-Urban Commuting Area codes 4 through 10 (confirm with trial site if unsure about your area's classification) - People who have a b...

Who might be able to join this trial: - People who have been clinically diagnosed with Chronic Obstructive Pulmonary Disease (COPD), a long-term lung condition that makes breathing difficult. - People who experience mucus-related problems (such as coughing up mucus) at least 3 times per week. - People who can speak and...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People with a moderate-to-severe asthma diagnosis confirmed by a lung specialist, with objective test results supporting the diagnosis (such as breathing tests showing reversibility or airway sensitivity) - People with a moderate-to-s...

**Who might be able to join this trial:** - People who have been diagnosed with both COPD (a lung condition that blocks airflow) and ILD (a condition that causes scarring or inflammation in the lungs), confirmed by clinical assessment, imaging, or tissue testing, following recognised international guidelines - People a...

**Who might be able to join this trial:** - People aged 40 to 80 years old - People who have been diagnosed with COPD for at least 1 year - People whose lung function test results fall within a specific range at the screening visit (confirm with trial site for exact values) - People who have been taking either triple...

**Who might be able to join this trial:** - People aged 40 years or older - People who have a confirmed diagnosis of COPD (a chronic lung condition) - People who have had a COPD flare-up in the past 6 months that required a hospital stay, medical treatment, or a visit to a doctor - People who a doctor and the trial tea...

Who might be able to join this trial: - You must be willing and able to sign and date a consent form agreeing to take part in the study - You must be 18 years of age or older - You must have already been diagnosed with COPD (a long-term lung condition) - You must be able to speak and understand Dutch - You must need to...

Who might be able to join this trial: - You are 40 years old or older - You have been diagnosed with a flare-up (sudden worsening) of chronic obstructive pulmonary disease (COPD), recorded under the medical code ICDJ44 Who may not be able to join: - You have a condition that requires treatment with a specific type of...

Who might be able to join this trial: - People who are admitted to specific hospital units, including General Observation Units, Internal Medicine wards, or a Hospital at Home program - People who are 65 years of age or older - People whose hospital admission was caused by a worsening of a heart condition, a breathing...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with moderate-to-advanced chronic kidney disease (stage 3 or 4) - People whose chronic kidney disease has caused anemia, with a hemoglobin (red blood cell) level below 11.5 g/dL - People who are currently being treated with medicati...

Who might be able to join this trial: - People who are already taking part in a remote rehabilitation program designed for people with COPD (a lung condition affecting breathing) - People who have an official diagnosis of COPD recorded in their medical records - People whose doctors expect them to live for more than on...

**Who might be able to join this trial:** - People aged between 18 and 45 years old - People who are willing and able to give their informed consent to take part in the study - People who have had ongoing lower back pain (not caused by a specific known condition) for more than 3 months, in the area below the bottom of...

Who might be able to join this trial: - People who are between 50 and 80 years old - People who have been screened for early lung cancer using a low-dose CT scan Who may not be able to join: - People who are younger than 50 or older than 80 years old - People who have not had a lung cancer screening Important: Always...

Who might be able to join this trial: - You are between 19 and 75 years old at the time of signing the consent form - You are already scheduled by your doctor to take Fexuclu tablets (fexuprazan) for an approved medical reason - You have at least one symptom that your doctor has decided needs medical treatment - You ar...

Who might be able to join this trial: - Adults over 18 years of age - People who have been diagnosed with moderate to very severe COPD (classified as GOLD stage II, III, or IV) - People who have already completed a pulmonary rehabilitation program at the trial site - People whose 6-minute walk test result was less than...

**Who might be able to join this trial:** - People who have been diagnosed with COPD (a chronic lung condition) according to the 2024 GOLD guidelines. - People whose lung function test results show an FEV1/FVC ratio below 60% (a specific measurement of how well air flows out of the lungs). - People with stable COPD wh...

**Who might be able to join this trial:** - You are between 40 and 80 years old (inclusive) at the time of signing the consent form. - You have a higher-than-normal level of a type of white blood cell called eosinophils in your blood. - You have been diagnosed with moderate to severe COPD (chronic obstructive pulmonar...

Who might be able to join this trial: - People who have been diagnosed with an obstructive lung disease (such as asthma or COPD) by a lung specialist. - People who are able to use an inhaler device correctly after receiving training. - People who have had a standard breathing (lung function) test done during a regular...

Who might be able to join this trial: - People who have been diagnosed with COPD (a long-term lung condition that makes breathing difficult) - People who have had a flare-up (worsening of symptoms) of their COPD at least once in the past year - People who live in Høje Taastrup or Copenhagen - People who are cognitively...

**Who might be able to join this trial:** - You are between 50 and 80 years old - You are a current or former smoker with at least 20 "pack-years" of smoking history (for example, one pack per day for 20 years, or two packs per day for 10 years) - You are willing to take part in an observational study and be contacted...

Who might be able to join this trial: - Adults aged 18 years or older. - People who have been diagnosed with one of the specific lung conditions listed by the trial, or healthy individuals participating as a control comparison. - People who are able to give written consent to participate. Who may not be able to join:...

Who might be able to join this trial: - People who have been diagnosed with COPD (Chronic Obstructive Pulmonary Disease) - People who are over 18 years of age - People who are starting a pulmonary rehabilitation programme (a structured exercise and education programme for lung conditions) Who may not be able to join:...

Who might be able to join this trial: - People who have been diagnosed with COPD (a lung condition) for at least 6 months - Both people receiving care as hospital inpatients and those attending as outpatients may be considered - People who have given their agreement to take part in the research - People who are 18 year...

Who might be able to join this trial: - Adults between 18 and 65 years of age - People rated as physical status category II or III by an anaesthesiologist, meaning they have mild to moderate health conditions (confirm with trial site) - People who have shoulder pain following a mastectomy (breast removal surgery) - Peo...

**Who might be able to join this trial:** - You have stones in your gallbladder AND in the main bile duct (the tube that carries bile from the liver to the small intestine), confirmed by a scan. - You have been diagnosed with a gallbladder or bile duct infection, yellowing of the skin/eyes (jaundice), or test results...

**Who might be able to join this trial:** - You are 18 years of age or older - You are able to understand the study information and are willing to sign a consent form agreeing to take part - You have previously received a stem cell transplant from a donor and have been diagnosed with active chronic graft-versus-host d...

**Who might be able to join this trial:** - People aged 18 or older who have voluntarily agreed to participate by signing a consent form - People who have previously received a stem cell transplant from a donor (using bone marrow, blood stem cells, or umbilical cord blood), using any of the standard transplant prepara...

**Who might be able to join this trial:** - Male participants who agree to use contraception or abstinence, and to avoid donating semen during the study and for at least 30 days after it ends - Female participants who are not pregnant or breastfeeding, and who either are not able to become pregnant, or who agree to us...

**Who might be able to join this trial:** - You must be able to understand and agree to take part in the study on your own (have the mental capacity to give consent) - You must be willing to sign and date a consent form agreeing to take part - You must be willing to follow all of the study's procedures and requirements...

**Who might be able to join this trial:** - You are 65 years of age or older (any gender) - You have been diagnosed with either COPD (a lung condition affecting breathing) or asthma, confirmed by a doctor using standard guidelines - You are currently using a specific type of inhaler that combines three medicines in one...

Who might be able to join this trial: - You must already be a participant in the Duke-COPDGene Phase 4 study - You must be willing to give your consent to take part in this study Who may not be able to join: - If you are not already enrolled in the Duke-COPDGene Phase 4 study, you would not be eligible to join this tr...

**Who might be able to join this trial:** - Adults between 18 and 80 years of age - People who have been diagnosed with kidney failure (also called end-stage renal disease) - People who have been receiving regular dialysis treatments for more than three months - People who are willing and able to agree to take part and...

**Who might be able to join this trial:** - You are 40 years old or older and are being seen as an outpatient (not currently admitted to a hospital) - You have chronic bronchitis, meaning you have had a mucus-producing cough for more than 3 months within a 2-year period - You are a current or former smoker with at leas...

**Who might be able to join this trial:** - You are able to understand the study requirements and are willing to sign a consent form before taking part - You are between 40 and 85 years old - You are a current or former smoker with at least 10 "pack-years" of smoking history (for example, smoking one pack a day for 10...

**Who might be able to join this trial:** - People aged 18 to 80 years old, of any gender - People who weigh at least 40 kg and have a body mass index (BMI) of 18 or above - People who have been receiving kidney dialysis (either hemodialysis or peritoneal dialysis) for at least 3 months before joining - People who hav...

Who might be able to join this trial: - People who are older than 18 years of age - People who have lung nodules that have been identified on a chest CT scan, confirmed as cancerous through a tissue test, and are planned to receive a treatment that destroys the nodule from outside the body (such as radiofrequency, micr...

Who might be able to join this trial: - People who attend primary health care services in Brazil. - People who have been diagnosed with one or more existing, ongoing (non-respiratory) long-term health conditions, such as heart disease, diabetes, or high blood pressure. Who may not be able to join: - People whose healt...

**Who might be able to join this trial:** - You must be willing and able to give your agreement (consent) for your anonymised health information to be used in this study. - You must be an adult (18 years of age or older). - You have COPD that is not well controlled, even though you are already using a combination of lo...

Who might be able to join this trial: - People who are able and willing to give written consent to participate. - People who are older than 40 years of age at the time of screening. - People who have smoked cigarettes heavily enough to have accumulated more than 10 pack-years of smoking history. - People who have been...

**Who might be able to join this trial:** - You were admitted to the hospital mainly because of a COPD flare-up, or you were admitted for serious breathing problems with a COPD flare-up also present. - You had a CT scan (a type of detailed X-ray) during your hospital stay, and the scan showed that you have lower than n...

**Who might be able to join this trial:** - Adults aged 18 or older - People whose condition has been stable for more than 3 weeks, meaning no recent flare-ups or worsening episodes - People whose blood oxygen level is 88% or above while resting, but who experience a meaningful drop in oxygen levels during a standard 6...

**Who might be able to join this trial:** - People who are aged between 35 and 80 years old. - People who have chronic bronchitis, meaning they have had a mucus-producing cough for at least three months a year, for two years in a row, and other causes of that cough have been ruled out. - People whose symptom burden sc...

Who might be able to join this trial: - People who currently smoke or used to smoke, with a history of at least 10 pack-years of tobacco use (this means, for example, smoking one pack per day for 10 years, or two packs per day for 5 years). - People who have been diagnosed with COPD, confirmed by a specific breathing t...

**Who might be able to join this trial:** This trial has two phases, each open to different groups of people. **Phase 1 – Healthy adults:** - Adults aged 18 or older who are in good health, with normal lung function test (spirometry) results and no history of chronic cough or other breathing conditions. **Phase 2 –...

**Who might be able to join this trial:** - People who have signed an informed consent form agreeing to take part - People who have been diagnosed with COPD or emphysema - People who are at least 22 years old - People whose body mass index (a measure of height and weight) falls between 18 and 32 - People who can walk...

Who might be able to join this trial: - People who are over 18 years old and are currently admitted to an intensive care unit (ICU) - People who have a moderate or severe chronic lung condition (specifically classified as GOLD stage 3 or 4) - People who have a build-up of too much acid in the blood due to breathing dif...

**Who might be able to join this trial:** - Adults of any sex aged 40 years or older. - People who have read, understood, and signed the required consent form that has been approved by an ethics committee. - People with a body mass index (a measure of body weight relative to height) between 17.6 and 40.0, and a body w...

Who might be able to join this trial: **If you have COPD:** - You are a man or woman aged between 40 and 75 years old - You have been diagnosed with COPD or have a medical history of it - You have smoked at least 20 pack years (roughly 1 pack a day for 20 years, or equivalent), and use of e-cigarettes/vapes is also al...

**Who might be able to join this trial:** **For all participants:** - Consent to take part in the trial has been given - Body weight is at least 45 kg and BMI is between 18 and 33 kg/m² - Heart tracing (ECG) results are normal, or only show minor changes that are not considered medically significant - Strict contracep...

Who might be able to join this trial: - People who are 40 years of age or older when they arrive at the emergency department. - People who have been clinically diagnosed with COPD and are visiting the emergency department due to a moderate or severe COPD flare-up. - A moderate flare-up means a sudden worsening of COPD...

**Who might be able to join this trial:** - People who have been diagnosed with COPD or emphysema - People who are at least 22 years old - People with a body mass index (BMI) between 18 and 32 - People who are able to walk between 100 and 400 metres in a 6-minute walk test at the baseline exam - People whose condition...

**Who might be able to join this trial:** - People who have been diagnosed with COPD (chronic obstructive pulmonary disease) by a lung specialist, confirmed using 2025 GOLD guidelines. - People whose lung function test results show that the airways are not severely restricted (FEV1 at or above 30% of the expected value...

Who might be able to join this trial: - Adults aged 18 years or older - People who are currently receiving hemodialysis (a kidney filtering treatment) three times per week, with each session lasting at least 4 hours - People whose dialysis is working well enough, as measured by a specific test called KT/V, with a score...

Who might be able to join this trial: - Children and teenagers aged 2 years old up to (but not including) 18 years old at the time of signing the consent forms. - People who have active, moderate to severe chronic graft-versus-host disease (a condition that can occur after a stem cell transplant) that requires treatmen...

**Who might be able to join this trial:** - People who live in the continental United States - People aged 40 years or older - People who have been told by a doctor that they have COPD - People who were admitted to a hospital for a COPD-related reason at least once in the past 12 months - People who use an inhaled medi...

Who might be able to join this trial: - Adults aged 18 or older - People who are being admitted to the Chest Department at Ain-Shams University Hospitals - People who have been diagnosed with a sudden worsening of a long-term lung condition called COPD (Chronic Obstructive Pulmonary Disease), confirmed using internatio...

**Who might be able to join this trial:** - People who have been diagnosed with stable chronic obstructive pulmonary disease (a long-term lung condition, often called COPD) - People whose condition matches certain Traditional Chinese Medicine (TCM) patterns related to weakness in the lungs, lungs and spleen, or lungs a...

Who might be able to join this trial: - Adults who carry one copy of a specific genetic variant called the SERPINA1 Z allele (a gene change linked to a condition called Alpha-1 Antitrypsin Deficiency) - People who have either had no serious flare-ups of a chronic lung condition (COPD) in the past year, or who have had...

Who might be able to join this trial: - Adults between 18 and 70 years of age - People who have had a spinal cord injury (SCI) for at least 1 year, with the injury located at or below a specific level of the spine (between the third cervical and eighth thoracic vertebrae) - People with an incomplete spinal cord injury,...

**Who might be able to join this trial:** - People aged 40 to 80 years old (any gender) at the first screening visit - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) according to 2025 GOLD diagnostic standards, with symptoms consistent with COPD for at least 1 year — this includes ong...

Who might be able to join this trial: - Adults aged 18 years or older, of any sex - People who have been diagnosed with COPD (a chronic lung condition), confirmed by a specific breathing test result (post-bronchodilator FEV1/FVC below 70%) - People who are currently being followed up through the relevant outpatient cli...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with chronic obstructive pulmonary disease (COPD) based on 2025 international COPD guidelines (GOLD criteria) - People with known risk factors for COPD, such as a history of smoking, exposure to harmful substances at work, or a...

**Who might be able to join this trial:** - Men, or women who meet specific eligibility criteria set by the trial site - People who have a higher-than-normal level of a type of white blood cell called eosinophils, measured through a blood test - People who have been diagnosed with moderate to severe COPD for at least...

**Who might be able to join this trial:** **Patients:** - People aged 18 or older - People who have previously been diagnosed with asthma or chronic obstructive pulmonary disease (COPD), confirmed using recognised international diagnostic guidelines - People who are able to cooperate and participate in the trial - Peo...

Who might be able to join this trial: - People aged between 40 and 80 years - People who have been diagnosed with Asthma-COPD Overlap Syndrome (ACOS), which is a condition involving features of both asthma and chronic obstructive pulmonary disease - People who score 23 or higher on the Nijmegen Questionnaire, a tool us...

Who might be able to join this trial: - People who have been admitted to hospital and diagnosed with a lung condition called Chronic Obstructive Pulmonary Disease (COPD), confirmed using internationally recognised guidelines - People aged 40 years or older - People whose breathing test results show a specific pattern o...

Who might be able to join this trial: - People who are between 40 and 80 years old - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) by a doctor for at least 1 year - People whose breathing test results fall within a specific range that indicates moderate-to-severe COPD (confirm with tr...

**Who might be able to join this trial:** - People aged between 50 and 80 years old - Men or women are eligible - People who have completed at least a primary school level of education - People who have been diagnosed with COPD, confirmed by specific breathing test results showing reduced lung function (confirm with t...

Who might be able to join this trial: - People who have been diagnosed with long-term (chronic) pain in a specific part of the body (peripheral pain) that was caused by an injury or surgery. - People between the ages of 19 and 80 years old. - People who are currently taking medication to manage their pain. - People who...

Who might be able to join this trial: - People who are 18 years of age or older. - People who have already been diagnosed with COPD. - For the inpatient group: people who are currently in hospital and have been assessed as having a moderate or severe COPD flare-up. - For the outpatient group: people who have had at lea...

**Who might be able to join this trial:** - People who have been admitted to hospital for at least 3 days due to a sudden worsening of COPD symptoms - People who can read and speak French, Dutch, or English - People aged 35 years or older - People who are able to give their informed agreement to participate in the tri...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of screening - People whose main problem is lower back pain that appears to be coming from the small joints along the spine (called facet joints), affecting both sides of the back, based on physical examination findings - P...

Who might be able to join this trial: - You are mentally able to understand and agree to take part in the trial yourself - You are 22 years of age or older - You are currently in hospital with low oxygen levels or difficulty breathing - You have been diagnosed with COPD (a lung condition that makes it hard to breathe)...

**Who might be able to join this trial:** *For the suspected asthma group:* - People aged 18 or older (or the legal age of consent in the country where the study is taking place) who have not yet been formally diagnosed with asthma - People experiencing symptoms such as wheezing, coughing, chest tightness, or shortnes...

**Who might be able to join this trial:** This trial has three separate groups. People may be considered for one of the following groups: **COPD Group:** - People who are older than 40 years of age - People who have been diagnosed with COPD (a chronic lung condition) - People whose COPD is currently in a stable condi...

Who might be able to join this trial: - People who are currently in hospital mainly because of a severe flare-up of COPD (a serious lung condition) - People who have had a breathing test (called spirometry) within the last 5 years that showed results consistent with COPD (confirm with trial site for exact values) - Peo...

**Who might be able to join this trial:** - You are between 40 and 80 years old. - You have been diagnosed with COPD (a lung condition) confirmed by breathing tests. - You have been using a breathing support machine at home (called NIV therapy) for at least 6 months, and you use it for more than 5 hours every day. - Yo...

Who might be able to join this trial: - People who are willing to join voluntarily and sign a consent form after being fully informed about the study - Healthy adults between 18 and 55 years old (inclusive), of any gender - Men who weigh at least 50kg and women who weigh at least 45kg, with a body mass index (BMI) betw...

Who might be able to join this trial: - People between 40 and 70 years of age - People who have been diagnosed with moderate-to-severe COPD (classified as GOLD stage II or III) - People whose COPD has been stable, meaning no flare-ups or worsening of symptoms in the past 4 weeks - People with a body mass index (BMI) be...

**Who might be able to join this trial:** - People aged 18 to 65 years (for the healthy volunteer part) or 35 to 75 years (for the patient part), with a body weight no higher than 120 kg and a body mass index between 18 and 32 - Women of childbearing potential who have a negative pregnancy test result - People who do...

Who might be able to join this trial: - People who are between 40 and 75 years old (inclusive) - People who have been diagnosed with COPD by a doctor for at least 1 year before the screening visit - People who have had at least 2 moderate COPD flare-ups, or at least 1 severe COPD flare-up, in the 12 months before the s...

Who might be able to join this trial: - People who have been diagnosed with Stage 1 or Stage 2 COPD (chronic obstructive pulmonary disease) - People whose COPD is accompanied by a "forward head posture," meaning the head sits noticeably further forward than normal - People whose craniovertebral angle (a measurement of...

Who might be able to join this trial: - Adults over 18 years of age - People who are scheduled to receive their first-ever bone marrow or stem cell transplant from a donor (known as an allogeneic transplant) Who may not be able to join: - People who are experiencing respiratory failure (serious breathing problems wher...

**Who might be able to join this trial:** - People who have been diagnosed with COPD (a lung condition) confirmed by a specific breathing test result (FEV1/FVC below 70%), following recognised medical guidelines - People whose condition is currently stable, based on a blood measurement showing the body's acid-balance i...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of joining the study - People who have signed and dated a consent form agreeing to take part, in line with the study's legal and ethical requirements - People with a confirmed diagnosis of moderate-to-very severe COPD (class...

Who might be able to join this trial: - People who are 40 years of age or older. - People with a smoking history of 10 pack-years or more (this means smoking roughly one pack of cigarettes per day for 10 years, or an equivalent amount over a different time period — confirm with trial site if unsure). - People who are w...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been diagnosed with COPD (a lung condition affecting breathing) confirmed using standard medical guidelines known as GOLD criteria - People whose COPD has been stable, meaning no serious flare-ups or hospital stays in the past 4...

**Who might be able to join this trial:** - People who have freely chosen to sign a written consent form agreeing to take part - People aged between 40 and 80 years old, of any gender - People with a body mass index (a measure of body weight relative to height) of 18 or above - People who have been formally diagnosed...

Who might be able to join this trial: - Adults who have been formally diagnosed with COPD, with medical records that support this diagnosis according to standard guidelines - People whose history includes known causes of COPD, such as a history of smoking - People who are already on a stable, guideline-recommended trea...

Who might be able to join this trial: - People who are 40 years of age or older - People who have been told by a doctor that they have COPD, or who are currently being treated for COPD - People who speak English - People who have access to the internet Who may not be able to join: - People who have a history of psycho...

**Who might be able to join this trial:** - You are between 40 and 80 years old (both ages included), and any gender may apply - You have been diagnosed with COPD (a lung condition) according to the 2025 international COPD guidelines - During a screening walking test, you are able to walk at least 150 metres but less t...

**Who might be able to join this trial:** - People who have been diagnosed with chronic obstructive pulmonary disease (COPD) for at least 12 months, based on recognised international guidelines. - People whose lung function test results show a specific level of airflow limitation — moderate to moderately severe (confi...

Who might be able to join this trial: - You have been officially diagnosed with COPD (a long-term lung condition that makes it hard to breathe) - You are currently in hospital being treated for COPD - You are a citizen of the Russian Federation - You are between 50 and 70 years old - You are willing to give your consen...

Who might be able to join this trial: - People who are willing and able to give consent for their anonymised health information to be used in this study. - People who are adults (18 years of age or older). - People who have Chronic Obstructive Pulmonary Disease (COPD) — a long-term lung condition — that is not well con...

Who might be able to join this trial: - You are between 40 and 75 years old (inclusive). - You have a history of smoking totalling at least 10 "pack-years" (for example, 1 pack per day for 10 years, or similar), and you have stopped smoking for at least one month before joining the study. - You have been diagnosed with...

Who might be able to join this trial: - People who are 18 years of age or older Who may not be able to join: - People who are unable to perform a spirometry test (a breathing test that measures how much air the lungs can hold and how fast air can be breathed out) Important: Always verify eligibility with the trial si...

**Who might be able to join this trial:** - You are between 40 and 75 years old. - You have been officially diagnosed with moderate to severe chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes breathing difficult. - Your condition has been stable for at least 4 weeks since your last ser...

Who might be able to join this trial: - People who are 40 years of age or older at the time they started taking the medication BDP/FF/GB (a combination inhaler also known as Trimbow®) - People who have a documented diagnosis of severe or very severe COPD before starting BDP/FF/GB - People who had a COPD symptom score (...

Who might be able to join this trial: - People who have been diagnosed with COPD (chronic obstructive pulmonary disease) according to standard medical guidelines known as the GOLD criteria - People who have not had a sudden worsening of their COPD symptoms (called an acute exacerbation) in the past month - People who a...

Who might be able to join this trial: - People who understand the study and are willing to sign a consent form agreeing to take part. - People aged 40 to 85 years old (male or female) at the time of signing the consent form. - People who weigh at least 40 kg. - People who have been diagnosed with COPD for at least 12 m...

Who might be able to join this trial: - Adults aged 18 or older, or children and teenagers aged 7 to 17, who have received a single or double lung transplant - People who have been diagnosed with a lung transplant complication called CLAD (at any stage) and have been prescribed a treatment called ECP therapy - People w...

**Who might be able to join this trial:** - Adults between the ages of 40 and 75 years. - People who have been diagnosed with a specific severity of Chronic Obstructive Pulmonary Disease (COPD), classified as "Group E" under international guidelines from 2023. - People who have been using a combination of three inhale...

Who might be able to join this trial: - You are between 18 and 80 years old - You have been diagnosed with a long-term breathing or lung condition, such as COPD, asthma, bronchiectasis, or interstitial lung disease - You are willing to learn and follow the instructions for using a special breathing measurement device c...

Who might be able to join this trial: - People who have been diagnosed with COPD (a chronic lung condition), with this diagnosis recorded in their GP records for at least 12 months - People aged 35 years or older - People who have been prescribed prednisolone (a steroid medication) 3 or more times in the past 12 months...

Who might be able to join this trial: - People who have had surgery to remove early-stage (stage I) lung cancer using a keyhole surgical technique (called VATS), where the surgery took place between 6 and 18 months ago - People who are still experiencing symptoms after their surgery, meaning at least one symptom has be...

Who might be able to join this trial: - You must have been diagnosed with COPD (a lung condition) for at least 6 months. - You must be currently receiving treatment as an inpatient in an internal medicine or surgical ward. - You must be willing to sign a consent form agreeing to take part in the study. - You must have...

Who might be able to join this trial: - People who have been diagnosed with pre-COPD or COPD (a lung condition affecting breathing) at any stage, as defined by 2023 international lung disease guidelines - Healthy people who do not have any ongoing or serious medical conditions Who may not be able to join: - People who...

Who might be able to join this trial: - People who are able to understand the study plan and are willing to sign a written consent form agreeing to take part. - People aged between 40 and 80 years old, of any gender. - People who have been diagnosed with moderate to severe COPD (a serious lung condition affecting breat...

**For Healthy Individuals** Who might be able to join this trial: - People who have never tried whole-body vibration therapy before and have never worked in a job or played a sport that regularly exposes them to vibration. - People aged between 18 and 65 years. Who may not be able to join: - People who are pregnant....

Who might be able to join this trial: - People who are 18 years of age or older. - People who have been referred to one of two specific psychiatric outpatient clinics (called FACT or OPUS) in the Capital Region of Denmark. - People who are beginning a new course of treatment at one of these outpatient clinics. - People...

Who might be able to join this trial: - People who are between 40 and 65 years old - Both men and women are eligible - People who experience breathlessness that falls within Grade 1 to 3 on a standard breathlessness rating scale (the mMRC scale) - People who have been diagnosed with mild COPD (chronic obstructive pulmo...

Who might be able to join this trial: - People who are 60 years of age or older - People who have been diagnosed with a lung condition called COPD (Chronic Obstructive Pulmonary Disease), confirmed using standard medical guidelines known as the GOLD criteria - People whose COPD has been stable, meaning no serious flare...

Who might be able to join this trial: - Adults aged 18 or older whose kidneys have failed completely and who are receiving regular dialysis treatment (the most advanced stage of chronic kidney disease). - People who have been on a stable, unchanged dialysis routine for at least 3 months before joining the trial. - Peop...

**Who might be able to join this trial:** - People who have been diagnosed with Grade I COPD, which is the mildest stage of this lung condition, where lung function testing shows results above 80% of what is considered normal - People between the ages of 40 and 65 years - Both men and women are eligible - People who ar...

Who might be able to join this trial: - Adults aged 18 or older - People who are receiving or have received a specific type of stem cell transplant (called a T-replete allogeneic hematopoietic cell transplant) for any medical reason, including people who have had a previous transplant - People whose stem cell donor is...

Who might be able to join this trial: - You are between 12 and 25 years old - You live in the Wai'anae area with the zip code 96792 - You receive your healthcare at Waianae Coast Comprehensive Health Center (WCCHC), including any of their school-based health centers - A WCCHC healthcare provider has identified you as s...

**Who might be able to join this trial:** - People who have been diagnosed with COPD (a chronic lung condition) - People who are 50 years of age or older - People who are current smokers or have smoked in the past - People who speak and understand Danish - People who are able to give their agreement to participate afte...

Who might be able to join this trial: - People who have given their written agreement to take part in the trial - People who weigh at least 45 kg and have a body mass index (BMI) between 18 and 33 - People whose heart rhythm test (ECG) results are normal or only slightly abnormal in a way that is not medically concerni...

Who might be able to join this trial: - People aged 40 years or older who have been officially diagnosed with COPD (a lung condition) - People who are currently using at least two inhaled medications for their COPD (such as a combination inhaler, or several separate inhalers) - People who have had at least one COPD fla...

Who might be able to join this trial: - Adults who are 40 years of age or older. - People who have been diagnosed with COPD (a lung condition), confirmed by a breathing test, and who have also tested positive for a stomach bacteria called H. pylori. - People who are willing to take part and agree to any required tests...

**Who might be able to join this trial:** - You are 40 years of age or older - You have been diagnosed with chronic obstructive pulmonary disease (COPD) — a long-term lung condition that makes it hard to breathe — either confirmed by a breathing test or based on your medical history - You are currently in the intensiv...

Who might be able to join this trial: - People with COPD who are on a breathing machine (ventilator) and have been assessed by their medical team as ready to begin the process of coming off it. - People who have been on invasive mechanical ventilation for more than 24 hours before a breathing trial is attempted. - Peop...

Who might be able to join this trial: - You must be 18 years old or older - You must be getting ready to leave an inpatient rehabilitation program at the Bern Rehab Center in Heiligenschwendi or the Insel Hospital, with no more than 10 days left before discharge - You must belong to one of these groups: people who have...

Who might be able to join this trial: - People who are 19 years of age or older - People in the COPD group who have breathing test results showing a specific airflow limitation (a ratio called FEV1/FVC below 0.70, measured after using a bronchodilator inhaler) - People in the asthma group who have been formally diagnos...

Who might be able to join this trial: - People between 50 and 80 years old who have been diagnosed with moderate or severe COPD (a long-term lung condition that makes breathing difficult) - People who have not had a sudden worsening of their COPD symptoms in the last 4 weeks - People who are physically able to take par...

Who might be able to join this trial: - People who are able to understand the study and are willing to sign a written consent form - People aged between 14 and 65 years - People who have been diagnosed with a specific form of chronic graft-versus-host disease (a condition that can occur after a stem cell or bone marrow...

**Who might be able to join this trial:** - People who are willing to sign a consent form agreeing to take part in the study and allow their medical records to be shared if needed. - People aged 40 to 85 years old at the time of signing the consent form. - People who are sexually active or capable of having children (...

Who might be able to join this trial: - You must be 18 years of age or older. - Your COPD must be stable, meaning you have not had a flare-up that needed treatment in the last 4 weeks. - You must have a confirmed COPD diagnosis, shown by a specific breathing test result (confirm with trial site). Who may not be able t...

Who might be able to join this trial: - People of any gender (male or female) may be considered. - People between the ages of 40 and 60 years old. - People who have been diagnosed with COPD (a long-term lung condition that makes it hard to breathe). - People who are willing to take part in the trial. Who may not be ab...

**Who might be able to join this trial:** - Adults between the ages of 40 and 80 - People whose breathing test results (taken after using an inhaler) show a specific pattern of reduced lung function, measured within a certain range (confirm with trial site for exact values) - People who have been using a stable combin...

Who might be able to join this trial: - People aged 18 or older - People who have been diagnosed with severe or very severe COPD (classified as GOLD stage 3 or 4) - People whose lungs show signs of being over-inflated (trapping too much air), confirmed by a specific breathing test called a nitrogen wash-out test, with...

**Who might be able to join this trial:** - People who have given written agreement to take part in the study - People with a body mass index (BMI) between 18.5 and under 35, and who weigh at least 50 kg (males) or at least 45 kg (females) - People who have been diagnosed with COPD (a long-term lung condition) for at...

**Who might be able to join this trial:** - People who have previously been diagnosed with COPD or chronic interstitial lung disease - People who have been prescribed supplemental oxygen for use during physical activity for at least 1 month before joining the trial - People aged 25 years or older - People whose symptom...

**Who might be able to join this trial:** - People who have been diagnosed with COPD based on their smoking history or exposure to other risk factors, confirmed by a specific breathing test result (post-bronchodilator FEV1/FVC ratio below 0.7) - People whose blood oxygen level at rest while breathing room air is above...