Obesity

**Who might be able to join this trial:** - You are able to understand, follow instructions, and give your agreement to participate. - You are at least 18 years old when joining the trial. - Your BMI was between 35 and 55 before you had your gastric band device implanted. - You received a specific type of gastric band...

**Who might be able to join this trial:** - You have been diagnosed with Prader-Willi syndrome (PWS) confirmed by genetic testing - A parent or legal guardian is willing and able to sign a consent form on the participant's behalf, and the participant themselves can sign an assent form if appropriate - You are in PWS Nu...

**Who might be able to join this trial:** - You are 18 years old or older and have had pain or physical difficulty in your knee, hip, or lower back for more than three months. - Your pain over the past week has been at least a 3 out of 10 on average, or your pain has interfered at least "somewhat" with your daily life...

"Who might be able to join this trial: - People with a Body Mass Index (BMI) greater than 30 kg/m² (this is a measure of body weight relative to height, and a BMI over 30 is generally classified as obese) Who may not be able to join: - Women who are currently pregnant Important: Always verify eligibility with the tri...

**Who might be able to join this trial:** - Adults who have obesity, meaning a body mass index (BMI) of 30 or higher - People aged 18 years or older - People who have already had two specific body composition measurements taken — one using a DXA scan (a type of low-dose X-ray that measures body fat and muscle) and one...

**Who might be able to join this trial:** - Adults aged 18 to 50 years of any race or gender. - For the single-dose part of the trial (Part A): people with a body mass index (a measure of weight relative to height) between 19.0 and 40.0. - For the multiple-dose part of the trial (Part B): people with a body mass index...

Who might be able to join this trial: - People who were 18 years of age or older at the time of their stomach-stitching (ESG) procedure - People who had a body mass index (BMI) between 30 and 50 at the time of their ESG procedure, which was performed using a specific device called the Overstitch Endoscopic Suturing Sys...

**Who might be able to join this trial:** - Adults between 18 and 60 years old (at least 80% of participants must be Caucasian, as of 2 September 2025) - For the single-dose part of the trial (Part A): people with a body mass index (BMI) between 19.0 and 40.0, and a body weight between 65 kg and 130 kg - For the multi...

**Who might be able to join this trial:** - People who are 45 years of age or older at the time of screening. - People with a body mass index (BMI) of 27.0 or higher at the time of screening (this is a standard measure of body weight relative to height). - People with a documented history of cardiovascular disease cau...

**Who might be able to join this trial:** - Your sleep study (overnight breathing test) must show that you stop breathing or have disrupted breathing at least 15 times per hour. - Your Body Mass Index (BMI) — a measure of weight relative to height — must be 27 or higher at the time of your initial check-up. - You must...

**Who might be able to join this trial:** - A parent, guardian, or legal representative must agree to the child taking part by signing a consent form before any study activities begin, and the child must also give their agreement (by signing or speaking their agreement, depending on their age and local rules). - Child...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) of 30 or higher, OR a BMI of 27 or higher combined with a prior diagnosis of at least one of the following: high blood pressure, abnormal cholesterol or fat levels in the blood, obstructive sleep apnea (where breathing repeatedly stops dur...

Who might be able to join this trial: - People who have been diagnosed with type 2 diabetes. - People who have been on a stable diabetes treatment plan for at least 3 months before the screening visit — this includes diet and exercise alone, or certain diabetes medications (note: some specific diabetes drug types are n...

**Who might be able to join this trial:** - People who were male or female at birth - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with knee osteoarthritis based on recognised medical criteria, with visible changes on X-ray showing moderate-level joint...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form. - People of any sex assigned at birth. Who may not be able to join: - People whose blood sugar control levels (measured by a test called HbA1c) are at or above a certain threshold at the screening s...

**Who might be able to join this trial:** **For healthy participants (certain study groups):** - People aged 18 to under 65, or aged 65 to 80 (depending on which group of the study) - People with a body mass index (a measure of body weight relative to height) between 18.5 and 30, and a body weight of at least 50 kg fo...

Who might be able to join this trial: - People who are staying in hospital overnight - People whose diagnosis matches the specific conditions listed in the trial's cohort study protocol for cost effectiveness (confirm with trial site) Who may not be able to join: - People who were admitted to hospital through the emer...

Who might be able to join this trial: - Adults over 18 who are obese, with a BMI above 30 - Adults over 18 who are overweight, with a BMI between 25 and 30 - Adults over 18 who are a healthy weight, with a BMI between 18.5 and 25 (these participants may be matched with others based on age, sex, and years of education)...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) of 25 or higher (this means being overweight or obese by standard medical measurement) - People aged between 18 and 60 years old - People who are right-handed - People whose weight has stayed roughly the same (within 5%) over the past 3 mo...

Who might be able to join this trial: - People with a body mass index (BMI) of 30 or higher (this is a standard measure of body weight relative to height) - People who are predominantly from east China, as the trial is designed to limit differences in population background - People who are willing and able to give thei...

Who might be able to join this trial: - You are between 18 and 65 years old - You are scheduled for abdominal surgery, either open surgery (laparotomy) or keyhole surgery (laparoscopy), for weight-loss surgery, gallbladder removal, or abdominal wall repair - You have a Body Mass Index (BMI) of 35 or above AND have been...

Who might be able to join this trial: - People between the ages of 60 and 80 - People who are either very inactive (sedentary) or highly physically active and trained - People with a body mass index (a measure of body weight relative to height) between 18 and 40 - People who do not smoke - People whose blood sugar leve...

Who might be able to join this trial: - Adults between 18 and 65 years old at the time of joining the trial - People with obesity, defined as having a Body Mass Index (BMI) greater than 30 kg/m² (a standard measure of body weight relative to height) - People who have undergone an obesity treatment — either a structured...

**Who might be able to join this trial:** - People with a history of heart or blood vessel disease, or those suspected of having it based on clinical findings or imaging tests such as ultrasound or specialised scans - People who have risk factors for hardening of the arteries (atherosclerosis), such as smoking, obesit...

Who might be able to join this trial: - Children between 6 and 18 years old whose body weight falls above the 95th percentile for their age and sex on standard growth charts Who may not be able to join: - Children who have a physical or mental health condition that would make it difficult for them to take part in phys...

Who might be able to join this trial: - Children from birth up to (but not including) 6 years of age may be eligible. - A parent or guardian must be willing and able to give their consent for the child to take part. - The child must attend a doctor's practice that is part of the TARGet Kids! research network. Who may...

Who might be able to join this trial: - People who weigh between 3,000 grams (about 3 kg, or roughly 6.6 lbs) and 180 kg (about 397 lbs) - People who are having a type of surgery that is considered suitable for this trial (confirm with trial site) - People who have signed a consent form agreeing to take part — if the p...

"Who might be able to join this trial: - You must be a pregnant woman or an infant. - Your pregnancy must be less than 23 weeks along. - You must live in Colorado. Who may not be able to join: - You are expecting more than one baby (such as twins or triplets). - You had cancer before becoming pregnant. - You had a psy...

**Who might be able to join this trial:** - Girls who do not have a long-term or ongoing medical condition - Girls whose body weight falls in the normal range (BMI between the 5th and 85th percentile for their age) or who are overweight or obese (BMI above the 85th percentile for their age) - Girls between 8 and 14 yea...

**Who might be able to join this trial:** - People aged 18 to 60 years of any race or gender - People with obesity, defined as a body mass index (BMI) between 30 and 40 kg/m² - People with insulin resistance, measured by a specific blood test score (called HOMA2-IR) greater than 2.2 - People with high blood pressure, e...

Who might be able to join this trial: - People who are 20 years of age or older - People with a body mass index (BMI, a measure of body weight relative to height) of 24 or above - For participants in the normal/control group, people with a BMI below 24 Who may not be able to join: - People who have not given their inf...

Who might be able to join this trial: - Children and young people between 3 months and 18 years old who have a known or suspected hormone-related (endocrine) disorder may be eligible to participate. - Family members between 3 months and 100 years old may be enrolled if their participation would help doctors diagnose a...

Who might be able to join this trial: - People with a BMI greater than 35 kg/m² (classified as the obese group) or a BMI less than 30 kg/m² (classified as the non-obese group) - People who are scheduled to have bariatric (weight-loss) surgery (obese group) or another type of abdominal surgery (non-obese group) Who may...

**Who might be able to join this trial:** - People between the ages of 18 and 75 who are generally healthy - People who have been diagnosed with type 2 diabetes or metabolic syndrome (a group of conditions including high blood pressure, high blood sugar, and excess body fat around the waist) **Who may not be able to...

**Who might be able to join this trial:** - African American women between the ages of 21 and 75 years old - Women who are overweight or obese, meaning a Body Mass Index (BMI) of 25 or higher - Women who live in Washington, DC Wards 5, 7, or 8, or in nearby parts of Prince George's County, Maryland - Women who own a sm...

**Who might be able to join this trial:** **For the mother:** - A planned caesarean delivery at 37 weeks of pregnancy or later - Carrying a single baby, in good general health, and aged 18 or older - Tested negative for infections that can be passed through bodily fluids, as part of standard early pregnancy care - Tes...

Who might be able to join this trial: - Twin babies born at Guangzhou Women and Children's Medical Center - Families who live permanently in Guangzhou, or who plan to stay in Guangzhou with their children for at least 3 years - Families for whom pregnancy health information was recorded before the birth Who may not be...

**Who might be able to join this trial:** - People with a body mass index (BMI) between 25 and 35 (a measure of body weight relative to height that falls in the overweight to moderately obese range) - People with a larger-than-average waist size — at least 94 cm for men or at least 80 cm for women - People who also hav...

Who might be able to join this trial: - People who are planning to have gastric bypass or sleeve gastrectomy (types of weight loss surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tract (the...

Who might be able to join this trial: - People who are planning to have gastric bypass or sleeve gastrectomy (types of weight-loss stomach surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tra...

Who might be able to join this trial: - You are planning to have gastric bypass or sleeve gastrectomy (types of weight loss surgery) in Central Norway - You are a Norwegian citizen Who may not be able to join: - You have previously had surgery where part of your digestive tract (stomach or intestines) was removed Imp...

Who might be able to join this trial: - People who are planning to have gastric bypass or sleeve gastrectomy (types of weight loss surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tract (stom...

Who might be able to join this trial: - People who are planning to have gastric bypass or sleeve gastrectomy (types of weight-loss stomach surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tra...

Who might be able to join this trial: - People who are planning to have a gastric bypass or sleeve gastrectomy (weight loss surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tract (stomach or...

Who might be able to join this trial: - People who are planning to have a gastric bypass or sleeve gastrectomy (types of weight loss surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tract (th...

Who might be able to join this trial: - Pregnant women aged 18 years or older, with pregnancy confirmed by a urine or blood test, or ultrasound. - Women who identify as American Indian or Hispanic. - Women who are willing to continue taking part in the study (both themselves and their child or children) for at least 3...

Who might be able to join this trial: - People who are planning to have a gastric bypass or sleeve gastrectomy (types of weight-loss stomach surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive t...

**Who might be able to join this trial:** - People who can read, understand, and speak English - People who are between 18 and 39 years old - People who are less than 20 weeks pregnant at the time of joining - People who are carrying a single baby (not twins or more) - People who are currently smoking at least one cig...

**Who might be able to join this trial:** - Children and teenagers between 5 and 18 years old - Those who are obese, meaning their body weight measurement (BMI) is above the 97th percentile for their age and gender, based on World Health Organization growth charts - A parent or guardian has given formal written consent...

Who might be able to join this trial: - People who had bariatric (weight loss) surgery exactly 5 years ago. Who may not be able to join: - People who do not wish to take part in the study. - People who are unable to receive or understand the information needed to make an informed decision about joining (confirm with t...

Who might be able to join this trial: - You are planning to have a gastric bypass or sleeve gastrectomy (types of weight loss surgery) at a hospital in Central Norway - You are a Norwegian citizen Who may not be able to join: - You have previously had surgery where part of your digestive tract (such as your stomach or...

Who might be able to join this trial: - People who are planning to have gastric bypass or sleeve gastrectomy (weight loss surgeries) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery where part of their digestive tract (stomach or...

Who might be able to join this trial: - People who are planning to have a gastric bypass or sleeve gastrectomy (weight loss surgery) at a hospital in Central Norway - People who are Norwegian citizens Who may not be able to join: - People who have previously had surgery to remove part of their digestive tract (such as...

Who might be able to join this trial: - People who are scheduled to have a surgical procedure called endoscopic gastric tubulization (a stomach-shaping procedure) at the Nouvel Hôpital Civil hospital in Strasbourg, France Who may not be able to join: - No specific exclusion criteria were listed in the official trial i...

**Who might be able to join this trial:** - Women who are pregnant and less than 13 weeks along in their pregnancy - People who are permanent residents or whose families plan to stay in Shenyang and the surrounding areas - Women who are planning to have their pregnancy check-ups and give birth at Shengjing Hospital **...

**Who might be able to join this trial:** - People who are female - People aged between 18 and 59 years old - People with a body mass index (BMI) of 25 kg/m² or higher (this means being classified as overweight or above — confirm with trial site if unsure of your BMI) - People who are willing to read and sign a consent...

Who might be able to join this trial: - People who were born at Guangzhou Women and Children's Medical Center and whose maternal grandmother's daughter (their mother) gave birth there - People whose maternal grandmother's daughter (their mother) has pregnancy health information available from that time Who may not be...

**Who might be able to join this trial:** - People of any racial or ethnic background - People with a body mass index (a measure of height-to-weight ratio) between 20 and 34.9 - People who sleep an average of 7 hours or more per night, as measured over a 2-week screening period - People who eat something within 1 hour...

Who might be able to join this trial: - Adults aged 18 or older who are scheduled to have laparoscopic weight-loss surgery (gastric bypass or sleeve surgery) at the participating hospital. Who may not be able to join: - People whose overall health before surgery is rated as very poor (above a certain medical risk leve...

Who might be able to join this trial: - People with a Body Mass Index (BMI) between 40 and 50 kg/m² (a measure of body weight relative to height). - People without any active physical illness that would interfere with movement or weight loss following bariatric (weight loss) surgery. Who may not be able to join: - Peo...

Who might be able to join this trial: - People who are eligible to enroll in the Brenner FIT and/or By Design Essentials programs (confirm with trial site) - A caregiver who lives in the same home as the child and has a Body Mass Index (BMI) over 30 (BMI is a number calculated from height and weight) - People who have...

Who might be able to join this trial: - People between 12 and 18 years of age (male or female) - People who can speak, read, and write in English - People who have a parent or guardian who can speak, read, and write in English - People whose parent or guardian has signed a consent form, and who have themselves agreed t...

**Who might be able to join this trial:** - People of any race, sex, or socioeconomic background may be considered. - Women who have not yet reached menopause may be eligible. - Women who are currently using a combined estrogen and progestin hormonal contraceptive (such as the pill, a skin patch, or a vaginal ring) ma...

**Who might be able to join this trial:** **For people with a flare-up of a chronic lung condition (AECOPD):** - People whose blood tests during their hospital stay show that carbon dioxide levels are too high and the blood has become too acidic, whether or not they are already using a breathing support mask - People...

Who might be able to join this trial: - Couples (a woman and her partner) who are trying to conceive within 12 months of joining the trial - The woman in the couple has a body mass index (a measure of weight relative to height) of 25 or above, which is generally considered overweight or obese - The woman has access to...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) between 23 and 39.9, or a body fat percentage between 32% and 50%. - People who are willing to have blood drawn as part of the study. - People who also have at least one of the following: a fasting blood sugar level between 100 and 125 mg/...

Who might be able to join this trial: - People with a Body Mass Index (BMI) over 30 (a measure of body weight relative to height) - People who are pregnant with one baby (not twins or more) - People who are between 11 and 15 weeks pregnant at the time of joining the trial - People who are currently getting less than 15...

Who might be able to join this trial: - People who are between 18 and 50 years old - People with a body mass index (a measure of body weight relative to height) between 25 and 30, or above 40 - People whose blood lactate levels (a substance produced by the body during physical activity) fall in either the top 25% or bo...

Who might be able to join this trial: - Women who are pregnant and less than 16 weeks along in their pregnancy - People between the ages of 21 and 39 years old - People whose body weight before pregnancy fell into a specific range (a BMI between 28 and 39, which generally means overweight to moderately obese — confirm...

**Who might be able to join this trial:** - People who have had any type of stem cell transplant (HSCT) and are at least 100 days past their transplant date at the time of their first study visit - People whose body mass index (BMI) is at or above the 85th percentile for their age and gender (a measure that places the...

**Who might be able to join this trial:** - Women who are postmenopausal and between 55 and 65 years old - Women with a Body Mass Index (BMI) — a measure of body weight relative to height — between 35 and 39.9 - Women who have been postmenopausal for more than 2 years **Who may not be able to join:** - Women who are c...

"Who might be able to join this trial: - Children and young people who are seen at the obesity/weight management outpatient clinic - A signed consent form agreeing to take part in the study must be in place Who may not be able to join: - There are no listed exclusion criteria for this trial — the trial site will be be...

Who might be able to join this trial: - People who were scheduled to have their first bariatric (weight loss) surgery between September 2020 and September 2021 - People with severe obesity (a body mass index over 40) who are not suitable candidates for weight loss surgery - People who use the internet regularly - The t...

Who might be able to join this trial: - People aged 10 to 18 years, of any gender - People with obesity, meaning a BMI at or above the 95th percentile for their age and gender - People who are willing to keep their current diet and lifestyle the same for the whole time they are in the study Who may not be able to join...

**Who might be able to join this trial:** - You are a man or a woman who has not yet gone through menopause - You are between 18 and 42 years old - Your body mass index (a measure of body weight relative to height) falls roughly between 23 and 35 - You are willing to drink a special type of water (called deuterium-labe...

**Who might be able to join this trial:** - Pregnant women who had a BMI of 30 or higher before pregnancy or in early pregnancy **Who may not be able to join:** - People who are under 18 years of age - People who need an interpreter or translator due to language difficulties - People carrying more than one baby (e.g.,...

Who might be able to join this trial: - Women who are between 7 and 20 weeks pregnant at the time of joining. - Women who are 16 years of age or older and considered able to make an informed decision. - Women whose ultrasound scan has shown no abnormalities with the baby. - Women who speak fluent English, so they can f...

**Who might be able to join this trial:** - You are being seen for the first time at the Nîmes University Hospital Obesity Clinic (whether as an inpatient, outpatient, or for a consultation). - You are being treated for obesity, meaning your Body Mass Index (BMI) is 30 or above. - You are covered by a health insurance...

"Who might be able to join this trial: - People who have given their signed consent to take part in the study - People who are 18 years of age or older - People who are overweight, living with obesity, or who have previously had bariatric (weight-loss) surgery Who may not be able to join: - No specific exclusion crite...

**Who might be able to join this trial:** - Babies born at full term (not premature) - Babies who were larger than average for their stage of pregnancy at birth **Who may not be able to join:** - Babies diagnosed with a significant genetic condition - Babies born with physical abnormalities that were present from birt...

Who might be able to join this trial: - People who are 18 years of age or older. - People with a body mass index (BMI) of 30 or higher (for the main study group), or a BMI between 25 and 30 (for the comparison group), measured one month after starting dialysis treatment. - People who have agreed to allow their health d...

**Who might be able to join this trial:** This trial has two separate groups — one for children and teenagers with high blood pressure (hypertension), and one for those with normal blood pressure (the comparison group). Criteria are listed for each. --- **HYPERTENSION GROUP** Who might be able to join this trial: -...

Who might be able to join this trial: - People who identify as Native American and work as an employee at Twin Arrows Casino - People between 21 and 65 years of age - People with a self-reported Body Mass Index (BMI) — a measure of body weight relative to height — above 24 kg/m² (confirm with trial site for how this is...

**Who might be able to join this trial:** - People who are overweight (BMI of 25 or above) or obese (BMI of 30 or above) and have chronic low back pain - People who have had general, non-specific low back pain for at least 3 months - People who are currently seeing someone for their low back pain - People whose first l...

**Who might be able to join this trial:** - People who are transgender and are currently receiving cross-sex hormone therapy, or people who are acting as a comparison group (controls) - People who are able to give informed consent; if the person is under 18 years old, all legal guardians must also give consent - For o...

Who might be able to join this trial: - People who are over 18 years of age. - People who have a Body Mass Index (BMI) of 30 or higher (this is a standard measure of body weight relative to height). - People who have voluntarily signed a written consent form agreeing to take part. Who may not be able to join: - People...

**Who might be able to join this trial:** - People aged 18 to 80 years old at the time of signing the consent form, either male or female - People who are willing and able to sign and date a written consent form agreeing to take part - People who are able and willing to follow all of the trial's procedures and require...

Who might be able to join this trial: - People aged between 18 and 65 years old - People with a body mass index (BMI) of 40 or above, or a BMI of 35 or above combined with a health condition related to obesity - People who have previously had a type of weight loss surgery called Roux-en-Y gastric bypass (RYGB) but have...

**Who might be able to join this trial:** - You are a woman who has gone through menopause (no periods for 12+ months, or you've had both ovaries or your uterus removed, confirmed by hormone levels if needed) - You are 21 years of age or older - You have a body mass index (BMI) of 30 or higher (or 25 or higher if you...

**Who might be able to join this trial:** - Children and young people who are older than 4 years and younger than 17 years old at the time of joining - Those whose body weight falls within a specific obesity range (based on international guidelines, with a standardised BMI score between 30 and 40) — not severely obese...

**Who might be able to join this trial:** - People aged between 18 and 79 years old, of any gender - People with a BMI (body mass index) over 30, which is generally considered obese - People with high blood pressure, specifically a reading above 130/80 - People with elevated insulin resistance, measured by a specific b...

**Who might be able to join this trial:** - People who have been approved for bariatric (weight loss) surgery and are scheduled to have a sleeve gastrectomy (a procedure that reduces the size of the stomach) - People with a BMI of 40 or higher (classified as morbid obesity) - People aged 18 to 65 years old - People wh...

**Who might be able to join this trial:** - You are between 13 and 30 years old (inclusive) - You have had a stem cell transplant (any type) and it has been at least 100 days since your transplant at the time of your first study visit - You are male or female - Your BMI (a measure of body weight relative to height) is...

Who might be able to join this trial: - The child must be a patient at the Cherokee Health Systems clinic in Cherokee Mills. - The child must be between 4 and 10 years old. - The child must have a Body Mass Index (BMI) — a measure of body weight relative to height — above the 85th percentile for their age group (confir...

Who might be able to join this trial: - People whose HbA1c blood sugar level falls between 5.7 and 6.4 (a range sometimes called "prediabetes") - People whose body mass index (a measure of body weight relative to height) falls between 27 and 45 Who may not be able to join: - People who have diabetes - People who regul...

**Who might be able to join this trial:** - People who identify as female - People aged between 18 and 65 years old - People who speak English or Spanish - People who are physically able to do light to moderate exercise, either based on a standard readiness questionnaire or with approval from a doctor - People who cur...

Who might be able to join this trial: - People who are 18 years of age or older Who may not be able to join: - People who are under 18 years of age at the time of screening - People who work or study within the Division of Cardiovascular Disease at UAB (University of Alabama at Birmingham), as their connection to the...

**Who might be able to join this trial:** - You are between 40 and 60 years old, of any gender or race - You have a normal or near-normal memory and thinking score on a standard screening test (confirm with trial site) - You are willing and able to have MRI scans - You are willing to have PET scans that involve inject...

Who might be able to join this trial: - Women aged 20 to 35 years old who are healthy and in their first trimester of pregnancy - Women whose baby is considered at risk of developing allergic conditions (atopy) Who may not be able to join: - People who currently have an active infection - People who currently have any...

Who might be able to join this trial: - People who are between 11 and under 16 years old - People with a BMI above 30 kg/m² or at or above the 95th percentile for BMI (a measure used to assess body weight relative to height and age) - People at a mid-stage of puberty development, known as Tanner stage 2, 3, or 4 (confi...

**Who might be able to join this trial:** - People who are generally healthy, without diabetes, kidney disease, heart or blood vessel disease, or any current use of medications that affect blood pressure or circulation **Who may not be able to join:** - People who have a history of heart or lung disease, or chronic ki...

**Who might be able to join this trial:** - Your kidneys are working at a reduced but not severely low level — specifically, a kidney function score (eGFR) between 20 and less than 60 (confirm with trial site if unsure of your score) - You are physically able to do resistance/strength training exercises - You have acce...

Who might be able to join this trial: - People with a Body Mass Index (BMI) of 35 or higher (a measure of body weight relative to height) - People between the ages of 18 and 50 - People who are not pregnant - People who have diabetes, meaning those currently taking diabetes medication or who have a fasting blood sugar...

**Who might be able to join this trial:** - You have been assessed as generally healthy by a doctor, based on a full health check including physical exam, blood pressure, heart rate, heart tracing (ECG), and blood tests - You are between 18 and 65 years old (inclusive) - Your Body Mass Index (BMI) is between 30 and 40,...

**Who might be able to join this trial:** - Women between 21 and 40 years of age - People with a body mass index (BMI) between 25 and 40 (a measure of body weight relative to height) - People who plan to stay living in Singapore for the next 4 years - People who are Chinese, Malay, Indian, or any combination of these t...

**Who might be able to join this trial:** - Adults aged 18 or older (the trial aims to enrol equal numbers of men and women) - People who agree to provide a genetic material sample (such as a blood or saliva sample for DNA testing) - People who are willing to follow all the requirements of the study protocol throughout...

Who might be able to join this trial: - Adults aged 18 or older. - People who are enrolled in the bariatric (weight loss) surgery program at UCLH, Homerton, or Whittington Hospitals, with a BMI over 30 kg/m². - People whose body weight has stayed within 5% of the same level over the past 3 months (meaning their weight...

**Who might be able to join this trial:** - Women aged 18 or older - Women with a Body Mass Index (BMI) of 30 or above (this is the medical measure used to classify obesity) **Who may not be able to join:** - People who have previously had weight-loss (bariatric) surgery - People who are currently pregnant or breastfe...

Who might be able to join this trial: - People who had a sleeve gastrectomy (a type of weight-loss stomach surgery) at least 18 months ago. - People whose body weight still meets the standard guidelines for weight-loss surgery — either a BMI of 35 or above with serious weight-related health conditions, or a BMI of 40 o...

**Who might be able to join this trial:** - You have a body mass index (BMI) of 40 or higher, or a BMI of 35 or higher with other weight-related health conditions, and have been assessed as suitable for weight-loss surgery under French health guidelines - You are right-handed - You have been identified as having a food...

Who might be able to join this trial: - Children between 6 and 12 years old - Children whose BMI (a measure of body weight relative to height) falls above the 90th percentile for their age, which is considered overweight - Children (and their parent or carer) who are able to give informed consent to participate Who ma...

Who might be able to join this trial: - People with a body mass index (BMI) between 30 and 39.9, which falls in the obese range - People who were born at altitudes below 2,100 meters (about 7,000 feet) above sea level - People who currently live in Tallahassee, Florida or the surrounding area - People who have complete...

Who might be able to join this trial: - People who identify as Black or African American - People who are overweight, meaning a Body Mass Index (BMI) above 24 (a measure of body weight relative to height) - People who have been diagnosed with prediabetes, previously diagnosed with gestational diabetes (diabetes during...

Who might be able to join this trial: - The household must be a Latino family with members from at least two generations living together (for example, children under 18 and adults, or adults and older relatives aged 65+), with between 3 and 5 people living in the home - At least two adults in the household must have a...

Who might be able to join this trial: - People aged between 18 and 45 years old - People with a body mass index (BMI) of 24 or higher (a measure of body weight relative to height) - People who have given written, informed consent to participate - People who have been confirmed by tissue testing to have a condition call...

Who might be able to join this trial: - People with a body mass index (BMI) of 25 or higher, or a waist-to-hip ratio above certain measurements that indicate excess abdominal fat (confirm with trial site for exact measurements) - People who are able to safely have an MRI scan (no metal implants or other reasons that wo...

**Who might be able to join this trial:** *People who have had Roux-en-Y gastric bypass surgery:* - Adults aged 18 to 70 who have previously had a type of weight-loss surgery called Roux-en-Y gastric bypass - People who have had at least one calcium-based kidney stone after that surgery - People whose urine oxalate le...

Who might be able to join this trial: - Adults between 18 and 65 years old, of any gender - People who have been diagnosed with asthma according to recognised international guidelines - People whose asthma is not well controlled (based on a specific asthma control score) even while using inhaled steroid medicines, with...

**Who might be able to join this trial:** - People who identify as female and are between 18 and 40 years old - People who have received full information about the trial's aims, methods, expected benefits, possible risks, and any discomforts involved, and have signed a consent form - People in the depression group: th...

Who might be able to join this trial: - Children who are between 9 and 12 years old - Children whose BMI (a measure of body weight relative to height) is at or above the 75th percentile for their age and sex - Children who live in the Greater Boston area Who may not be able to join: - Children who dislike or refuse to...

**Who might be able to join this trial:** - People who have had a traumatic spinal cord injury - People who are at least 1 year past the date of their injury - People who are 20 years of age or older - People with a BMI greater than 22 kg/m² at the time of enrollment - People who speak and understand English or Spanis...

**Who might be able to join this trial:** - People who have been diagnosed with a metabolic disease. - People who are able to understand what the research involves. - People who are willing to take part and able to sign a consent form. **Who may not be able to join:** - People who are under 18 years old or over 80 yea...

**Who might be able to join this trial:** - You have been diagnosed with high blood pressure that has no known underlying cause (also called essential hypertension) - You are between 18 and 70 years old - You are able to read, understand, and sign a consent form agreeing to take part **Who may not be able to join:** -...

Who might be able to join this trial: - People who are thinking about having Endoscopic Bariatric Therapy (EBT) for weight loss - People with a Body Mass Index (BMI) over 30, without any weight-related health conditions - People with a BMI over 27, who also have health conditions related to their weight - People who ar...

**Who might be able to join this trial:** - Children who are 5–6 years old (a limited number of children aged 4–5 or 6–7 may also be considered) - Children who are able to communicate in Chinese - Children who are able to take part in physical activity in a standard kindergarten environment **Who may not be able to jo...

**Who might be able to join this trial:** - People aged 14 to 21 years old - People who own an iPhone or are willing to use one provided by the study - People who can read and speak English - People who answer in a specific way on a short 5-question survey about motivation to manage their weight — for example, people w...

**Who might be able to join this trial:** - People between 18 and 60 years old (male or female) - People who have not intentionally tried to lose weight in the past 6 months **Who may not be able to join:** - People who use tobacco products at a level above "Very Low Dependence" on a standard nicotine dependence scale...

**Who might be able to join this trial:** - People who are overweight or obese (a body mass index of 25 or higher) - People who work in a desk-based job where at least 75% of their workday (8 hours or more) is spent sitting, whether at home or in an office - People who are considered "at risk" for diabetes, which mean...

**Who might be able to join this trial:** - Healthy volunteers with a BMI between 18 and 39.9 (the trial is looking for people across four weight ranges: normal weight, overweight, grade 1 obesity, and grade 2 obesity) - People whose kidneys are working at a sufficient level (a kidney function score above 50 ml/min, as...

**Who might be able to join this trial:** - Adults who identify as being of Latino heritage - People who are a caregiver (not necessarily a biological relative) for a child or grandchild between 2 and 5 years old who has been assessed as overweight or obese (with a body mass index above the 85th percentile for their a...

Who might be able to join this trial: - People who are pregnant and at 33 weeks of pregnancy or earlier - People who are carrying one baby (not twins, triplets, etc.) - People whose body weight before pregnancy falls into the overweight or obese range (a BMI of 25 or higher, based on self-reported height and weight bef...

Who might be able to join this trial: - People who have been living permanently in Jakarta, Surabaya, or Yogyakarta City for at least 6 months - People who are generally healthy with no known illnesses - Male or female adolescents between the ages of 12 and 17 years old - People who are overweight or obese, based on a...

Who might be able to join this trial: - You are a two-parent family where one or both parents are currently serving in the active duty military - You are expecting your first child and are no more than 7 months pregnant at the time of joining Who may not be able to join: - Either parent has an active diagnosis of canc...

**Who might be able to join this trial:** - People with a body mass index (BMI) of 40 or below (BMI is a measure based on height and weight) **Who may not be able to join:** - People whose body weight has changed by 5% or more in the past six months - People with a known serious heart, neurological, kidney, liver, or...

**Who might be able to join this trial:** - People of any sex, race, or ethnic background who fall into one of three groups: adults aged 18–30 with a healthy weight (BMI 18.5–24.9), adults aged 18–30 with obesity (BMI 30–39.9), or adults aged 65 and older with obesity (BMI 30–39.9) - People who live independently in t...

Who might be able to join this trial: - Adults between the ages of 18 and 60 who have been confirmed to have obesity or to be overweight Who may not be able to join: - People who are severely ill - People who have other long-term (chronic) health conditions Important: Always verify eligibility with the trial site dir...

Who might be able to join this trial: **Child Care Centers:** - The center must be open all year round - The center must be licensed and have no plans to close within the next 2 years - The center must have been running for at least 1 year - The center must have at least two classrooms for children aged 2 to 5 years o...

Who might be able to join this trial: - People who have signs and symptoms of heart failure - People whose heart is pumping at a rate greater than 50% of its normal capacity (known as an ejection fraction above 0.50) - People with measurable evidence that their heart muscle is not relaxing properly between beats (diast...

Who might be able to join this trial: - People between the ages of 18 and 64 - People with a Body Mass Index (BMI) of 25 or higher (BMI is a measure based on height and weight) - People who have a bathroom scale at home or can regularly access one - People who own a smartphone and are willing to download a mobile app f...

**Who might be able to join this trial:** - People aged 16 to 65 years - People who are stable and being seen as outpatients (not currently admitted to hospital) - People who have been diagnosed with an intellectual or developmental disability (IDD) - People who have been taking an antipsychotic medication at a stable...

**Who might be able to join this trial:** - People between 20 and 50 years of age - People in the study group with a body mass index (BMI) between 25 and 40 kg/m² (a measure of body weight relative to height that falls in the overweight to obese range) - People in the control group with a BMI between 18.5 and 24.9 kg/m...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been officially diagnosed with morbid obesity (a high level of excess body weight that affects health) - You have been assessed as being in a moderate health risk category for surgery, known as ASA level II or III (confirm with t...

Who might be able to join this trial: - Pregnant women with a body weight considered normal range (BMI under 30) - Pregnant women living with obesity (BMI of 30 or above) - Pregnant women who have a condition affecting how their body manages blood sugar (such as gestational diabetes or similar) - Pregnant women who hav...

Who might be able to join this trial: - People who are already taking part in the Predict study - Women who are planning to become pregnant or who are less than 13 weeks pregnant - People with a BMI (body mass index) either above 30 or between 18 and 25 - People who can speak and read Dutch - People who are willing to...

**Who might be able to join this trial:** This trial has several separate groups, each with different criteria. A person would need to meet the criteria for the specific group they are being considered for. **COMIDA group:** - People who identify as Mexican American or Mexican - People who are seeking services at the...

Who might be able to join this trial: - People with a BMI (body mass index) between 30 and 45 kg/m² Who may not be able to join: - People who are unable or unwilling to cooperate with the trial requirements - People who smoke heavily - People who are pregnant or who have given birth in the last 6 months - People who h...

**Who might be able to join this trial:** - People who meet the SICOB criteria (an Italian surgical society's standards) for sleeve gastrectomy, a type of weight-loss stomach surgery (confirm with trial site) - People who have previously had a sleeve gastrectomy or gastric bypass surgery and have regained weight, and w...

Who might be able to join this trial: - Children who are generally healthy - Children who are between 5 and 7 years old - Children whose BMI is at or above the 5th percentile for their age - The child's biological mother must also be their primary caregiver and take part in the trial - The child's mother must be able t...

**Who might be able to join this trial:** - Children with Prader-Willi syndrome (before their teenage years) who have been confirmed to have the condition through genetic testing - Children who meet the medical definition of obesity - Children who are not currently taking part in, and have not taken part in, any other...

Who might be able to join this trial: - Women who are currently breastfeeding and who had a normal, overweight, or obese body weight before becoming pregnant, based on World Health Organization definitions Who may not be able to join: - Women who have Type 1 diabetes, Type 2 diabetes, or diabetes that developed during...

Who might be able to join this trial: - People who are between 18 and 70 years old - People with a BMI between 25 and 45 kg/m² (confirm with trial site if unsure about BMI) - People who have regular weekly access to the internet, either through a smartphone, or a home or work broadband/Wi-Fi connection Who may not be...

**Who might be able to join this trial:** - People aged 18 to 40 years old - People with a Body Mass Index (BMI) between 30 and 40 (a measure of body weight relative to height) - People whose weight has been stable — changing by no more than 3kg — for at least approximately 2 months - People who do not have a regularly...

**Who might be able to join this trial:** - People who are currently pregnant - People who are between 8 and 18 weeks pregnant at the time of screening - People carrying a single baby (not twins, triplets, etc.) - People who smoke 20 or fewer cigarettes per day - People of any pregnancy history (first-time pregnancy o...

**Who might be able to join this trial:** - You are between 18 and 65 years old. - You are overweight or obese, meaning your body mass index (BMI) is 25 or higher. - You have had general low back pain (not caused by a specific known condition) for at least 3 months and are currently seeking care for it. - Any leg pain...

Who might be able to join this trial: - People who are pregnant with one baby (not twins or more) - People with a BMI (body mass index) of 25 or higher at the time of the trial Who may not be able to join: - People who have high blood pressure that existed before or outside of pregnancy - People who had diabetes (type...

**Who might be able to join this trial:** - People who are 50 years of age or older - People with a body mass index (BMI) of 25 or higher (this is a standard measure of body weight relative to height) - People whose weight has stayed roughly the same (within 2 kg) over the past 6 months - People who are willing to give...

Who might be able to join this trial: - You have at least one of the following health conditions: being overweight or obese, having prediabetes, having abnormal cholesterol or fat levels in your blood, or having high blood pressure. - A Traditional Chinese Medicine practitioner has assessed you as having a specific pat...

Who might be able to join this trial: - Adults who are obese and are between 20 and 45 years of age (both men and women) Who may not be able to join: - People who have diabetes or a fasting blood sugar level above 126 mg/dL - People with low red blood cell levels (anaemia) — specifically, women with a haemoglobin leve...

Who might be able to join this trial: - People who are over 18 years old - People with a BMI of 25 or higher and a body weight under 396 lbs - People who own a smartphone and are willing to install an app called SMARTer - People who are not currently enrolled in a formal weight loss program Who may not be able to join...

**Who might be able to join this trial:** - People with a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher if they also have at least one health condition related to their weight (such as high blood pressure or high cholesterol) - People who have tried at least once in the past to lose weight through di...

**Who might be able to join this trial:** - People who are between 18 and 64 years old - People with a Body Mass Index (BMI) of 25 or higher (BMI is a number calculated from height and weight — the trial site can help clarify this) - People who have access to a device such as a computer or smartphone that can open a we...

Who might be able to join this trial: - People diagnosed with heart failure where the heart is pumping at a reduced level (specifically, where the heart pumps out between 20% and 45% of blood with each beat) - People with a body mass index (a measure of body weight relative to height) above 27.5 kg/m² Who may not be a...

Who might be able to join this trial: - People between 18 and 40 years old - People with a Body Mass Index (BMI) above 25 (a measure of body weight relative to height) - People who do not have any heart or lung conditions - People whose medications have remained the same for at least 3 months - People whose weight has...

**Who might be able to join this trial:** - People between 5 and 21 years old at the time of joining the trial - People who are planning to start, or who are already receiving, a phase of cancer treatment called "maintenance" or "continuation" chemotherapy for a type of blood cancer called ALL (acute lymphoblastic leuk...

**Who might be able to join this trial:** - Women who have been assessed as suitable candidates for weight-loss (bariatric) surgery, with a BMI over 40, or a BMI over 35 with at least one related health condition that surgery could help improve - Women aged between 18 and 45 years old - Women using an effective form o...

Who might be able to join this trial: - People with a Body Mass Index (BMI) of 30 or higher (considered obese range) - People aged 18 or older - People who have been diagnosed with a specific type of uterine cancer called endometrioid endometrial cancer, confirmed through a tissue sample test - People whose cancer is a...

**Who might be able to join this trial:** - People aged 18 to 70 years (male or female) - People who had a sleeve gastrectomy or Roux-en-Y gastric bypass surgery at least 18 months ago - People who have regained at least 5% of their lowest weight reached after surgery - People with a body mass index (BMI) of 30 or abo...

**Who might be able to join this trial:** - Children of preschool age who are enrolled at one of the participating childcare or preschool centres **Who may not be able to join:** - Children who have severe food allergies that would prevent them from eating the foods used in the trial - Children who have a developmenta...

**Who might be able to join this trial:** - Children between the ages of 5 and under 18 years old - Children who agree to take part themselves, and whose parent or guardian also gives their permission **Who may not be able to join:** - Children whose ability to fully understand and agree to what the trial involves may...

**Who might be able to join this trial:** - People who are able to give informed consent to participate - People aged between 18 and 75 years old - People with a BMI of 40 or above, or a BMI of 35 or above along with a health condition related to obesity - People who are scheduled to have a primary weight-loss surgery...

**Who might be able to join this trial:** - Children who are between 8 and 12 years old - Children whose weight falls in the normal range for their height and age (BMI between the 5th and 85th percentile) - Children whose weight falls in the overweight or moderately obese range for their height and age (BMI at the 85t...

**Who might be able to join this trial:** - You must be able to communicate clearly with the research team and be able to give your written consent to take part. - You must be 18 years of age or older (either male or female). **Who may not be able to join:** - You have taken antibiotic tablets or capsules in the last...

**Who might be able to join this trial:** - You are having a type of weight loss surgery called laparoscopic Mini Gastric Bypass (MGB) for severe obesity or health problems related to your weight **Who may not be able to join:** - You do not wish to give your consent to take part in the study - You are having a repeat...

Who might be able to join this trial: - Infants who appear to have symptoms of MEHMO syndrome and are at least 1 week old, or family members without symptoms who are at least 1 month old - People who show signs or symptoms that suggest MEHMO syndrome, where genetic testing has either not been done or has given unclear...

**Who might be able to join this trial:** - People aged 18 to 50 years old - People with a body mass index (BMI) between 25 and 40 (a measure of body weight relative to height) - Both men and women are eligible - People who are not currently pregnant or breastfeeding **Who may not be able to join:** - People with Type...

**Who might be able to join this trial:** - People between 30 and 80 years old - People who are overweight or obese, meaning their body mass index (a measure of body weight relative to height) is 25 or above - People who are already scheduled to have a routine colonoscopy (a procedure to examine the bowel) for colon ca...

**Who might be able to join this trial:** **For the child:** - The child is between 6 months and under 18 months old at the time of joining the study - The child was born at 37 weeks of pregnancy or later, with no signs of malnutrition found at routine health visits - The child's household showed signs of food insecur...

**Who might be able to join this trial:** - People between 18 and 65 years old - People with severe obesity (a BMI of 40 or above), or people with a BMI between 35 and 40 who also have at least one related health condition that surgery is expected to improve (such as high blood pressure, type 2 diabetes, sleep apnea, h...

**Who might be able to join this trial:** - You are between 18 and 64 years old at the start of the study - Your Body Mass Index (BMI) — a measure of body weight relative to height — is 30 or above - You currently receive your healthcare through Missouri Highlands - You are able to understand and are willing to sign an...

Who might be able to join this trial: - People who are covered by social security - People who have given free, informed, and written consent before joining the trial - People who are aged 18 or over but under 45 years old at the time of joining - People who have had pre-eclampsia (a serious condition during pregnancy...

Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the trial - People aged 65 or older (for Groups 1, 2, and 3) - People aged 18 to 65 (for Groups 4, 5, and 6) - People who had weight loss (bariatric) surgery between 1 and 10 years ago (for Groups 1, 2, 4, and 5) - Pe...

**Who might be able to join this trial:** - People with a BMI between 25 and 55 kg/m² - People who live in a non-urban or rural area, as defined by recognised rural classification systems (confirm with trial site) - People who are able to walk at a moderate pace for at least 10 minutes without stopping, with no physica...

Who might be able to join this trial: - The child must be 4 or 5 years old at the start of the study - The parent or main caregiver must have legal custody of the child (at least 50% of the time) - The parent or main caregiver must be mainly responsible for feeding the child outside of childcare, meaning they are prese...

**Who might be able to join this trial:** - Adults aged 18 years or older - People with a BMI over 40 kg/m², which is classified as class III (severe) obesity - People diagnosed with moderate or severe ARDS (a serious lung condition that makes breathing very difficult), as defined by a specific medical standard called...

Who might be able to join this trial: - Generally healthy men and women between the ages of 18 and 70 - People with a Body Mass Index (BMI) between 30 and 40 (a measure of body weight relative to height) - People who do less than 1 hour of exercise per week - Women who are either pre-menopausal (still having periods) o...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) of 30 or higher (BMI is a number calculated from height and weight) - People with a BMI between 27 and 30 who also have at least one health condition related to their weight (confirm with trial site for which conditions qualify) - People wh...

Who might be able to join this trial: - People aged 14 to 19 years old - People who identify as a girl - People whose BMI falls at or above the 85th percentile for their age and sex (this means their weight is higher than at least 85% of others of the same age and sex — confirm with trial site if unsure how this applie...

**Who might be able to join this trial:** - People who are aged between 18 and 70 years old - People who are female - People who weigh at least 35 kg - People who have been diagnosed with a type of invasive breast cancer (called invasive breast adenocarcinoma) that responds to the hormone oestrogen, confirmed by a tis...

**Who might be able to join this trial:** - You are able to give written consent to take part in the study. - You are generally healthy. - You are a non-smoker. - You are male or female. - You are between 60 and 75 years old. - Your Body Mass Index (BMI — a measure of body weight relative to height) is between 25 and 4...

**Who might be able to join this trial:** - People who are able to give informed consent, are willing to follow all study procedures, and are available for the full duration of the trial. - People with a body mass index (BMI) of 30 or higher, OR a BMI of 27 or higher alongside at least one weight-related health condit...

**Who might be able to join this trial:** - People with a body mass index (BMI) between 18.5 and 35 kg/m² (a measure of body weight relative to height) - People who speak French - People who are able to travel to the Research Center of the Institut Universitaire de Cardiologie et Pneumologie de Québec for a study visit...

Who might be able to join this trial: - People who have been diagnosed with prediabetes (blood sugar levels higher than normal but not yet at diabetes levels) - People who have been diagnosed with type 2 diabetes - People who have been diagnosed with pre-hypertension (blood pressure slightly above normal) - People who...

**Who might be able to join this trial:** - People with a BMI of 40 or higher at the time they are admitted to hospital to have their labour started - People who speak English or Spanish - People who are between 34 weeks and 42 weeks and 6 days pregnant - People aged 18 years or older - People carrying a single baby w...

Who might be able to join this trial: - The child and their parent or guardian must agree to take part, with the child giving their assent and the parent giving formal consent - The child must be between 7 and 12 years old and have a body weight classified as overweight or obese (at or above the 85th percentile for BMI...

Who might be able to join this trial: - The parents or guardians taking part must speak German - Families from any ethnic background or race are welcome - The child must live in the same home as the parent or guardian who is participating - The child must have a BMI (a measure of body weight relative to height) above t...

Who might be able to join this trial: - People who identify as Chinese cancer survivors attending a one-time, in-person survivorship care clinic - People who speak Cantonese or Mandarin - People aged 18 or older - People who have been diagnosed with early-stage cancer (stage 0 to II) - People who have finished their ma...

**Who might be able to join this trial:** - People aged between 18 and 65 years old at the time of their weight-loss surgery - People who had one of two specific types of weight-loss surgery: a sleeve gastrectomy (stomach stapling) or a Roux-en-Y gastric bypass - People who, at the time of surgery, had a BMI of 35 or h...

**Who might be able to join this trial:** - The child's parent or caregiver must be willing to give their child only whole milk or only 1% milk (assigned randomly) for one year - The family must have access to a smartphone and also a tablet, laptop, or computer with internet and email at home - The parent or caregiver...

Who might be able to join this trial: **Parts A and B (Healthy volunteer portion):** - Men and women aged 18–55 who are generally in good health at the time of screening - A body mass index (BMI) of 30 or higher (a measure of body weight relative to height) - Normal or medically unimportant results on health checks at...

Who might be able to join this trial: - People aged 10 to 21 years old whose BMI is above the 95th percentile for their age (this means their weight is higher than 95% of people the same age, which doctors consider obesity) Who may not be able to join: - People who have previously been diagnosed with Prader-Willi Synd...

**Who might be able to join this trial:** - Women between the ages of 20 and 45 years old - Women who have regular menstrual cycles, meaning no more than one missed period in the past year - Women who are not currently pregnant and are not planning to become pregnant - Women who have not been breastfeeding in the last...

Who might be able to join this trial: - People who have been diagnosed with obesity and are scheduled to undergo weight-loss or metabolic surgery. Who may not be able to join: - People whose obesity is being treated through non-surgical methods (such as medication, diet, or lifestyle programmes). Important: Always ve...

Who might be able to join this trial: - Adults aged 18 or older - People who are able to read and understand the study information and consent form - People with a BMI over 35 who also have at least one other related health condition, or people with a BMI over 40 - People whose case for weight-loss digestive surgery ha...

**Who might be able to join this trial:** **As a shift worker participant:** - Works in the healthcare sector or an industrial setting - Is employed or self-employed - Is 21 years of age or older - Works at least 24 hours per week - Has been doing shift work for more than 3 years and is currently working night shifts...

Who might be able to join this trial: - People who can understand written and spoken Swedish - People who have previously had Gastric Bypass surgery - People who have been diagnosed with gestational diabetes (diabetes during pregnancy) according to the local criteria used by the trial site - People who are planning to...

**Who might be able to join this trial:** - Your Body Mass Index (BMI) is between 30 and 40, meaning you are classified as moderately obese - You are older than 18 and younger than 60 years old - You have tried multiple diets in the past without lasting success **Who may not be able to join:** - You have a condition a...

**Who might be able to join this trial:** - People who are severely obese, with a BMI between 40 and 60 - People who understand and are willing to attend follow-up appointments over a long period of time - People who agree to take part in the study **Who may not be able to join:** - People who are unable to understand...

**Who might be able to join this trial:** - People aged 6 to 28 years (male or female) - People who gained weight rapidly around the time of their brain tumor diagnosis or treatment, as assessed by an experienced hormone specialist (for example, a notable increase in weight-for-age measurements within the first 6 mont...

**Who might be able to join this trial:** - People who are aged between 18 and 60 years old at the time of screening - People who have severe and complex obesity, meaning a BMI over 35 (or over 32.5 for people with South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean heritage), along w...

**Who might be able to join this trial:** **Main participant (called the "Index Participant"):** - People who identify as Black or Hispanic - Men or women aged 18 or older - People with a body mass index (BMI) over 30, as measured by study staff - People who have access to a home computer or smartphone and are willing...

**Who might be able to join this trial:** - Men between the ages of 22 and 40 years old. - Men with a BMI of 30 or above (classified as obesity by World Health Organization standards). - Men who are willing and able to give informed consent and attend ongoing appointments at the Reproductive Center of the Third Affili...

**Who might be able to join this trial:** - People who have been diagnosed with morbid obesity (a severe form of obesity) **Who may not be able to join:** - People who have serious conditions affecting major body systems, a fever, or known long-term inflammatory conditions that cause a specific protein level (CRP) to...

Who might be able to join this trial: - Thai women between 18 and 45 years old who are classified as obese and have an upcoming bariatric (weight-loss) surgery appointment at Chulalongkorn Hospital - People who need a form of contraception (birth control) - People who are able to use non-hormonal birth control methods...

**Who might be able to join this trial:** - Thai women between 18 and 45 years old who are living with obesity and have a scheduled bariatric (weight-loss) surgery appointment at Chulalongkorn Hospital - Women who need a form of birth control - Women who are able to use non-hormonal birth control methods during the stu...

Who might be able to join this trial: - People with a Body Mass Index (BMI) over 27.5, which is a measure of body weight relative to height that falls in the obese range (obese group) - People with sarcopenia, which means having low muscle strength (weak grip strength — below 26kg for men or below 18kg for women), and/...

Who might be able to join this trial: - Adults who receive care at Johns Hopkins Medicine and live in Baltimore City, or adults who receive care at Johns Hopkins Community Physicians Hagerstown or Family Healthcare of Hagerstown and live in Washington County - People living in an area ranked above the 75th percentile o...

Who might be able to join this trial: - Women between 60 and 79 years old who live independently in the community (not in a nursing home or similar care facility) - People with either a normal body weight range (BMI 18.5–24.9 and body fat below 25.9%) or obesity (BMI 30–39.9 and body fat above 32%) - People who have th...

Who might be able to join this trial: - Adults aged 18 or older who have a body mass index (BMI) over 30, which is the medical measure used to classify obesity - People who have been diagnosed with a liver or bile duct condition, confirmed using a special scanning test called FibroScan Who may not be able to join: - P...

Who might be able to join this trial: - People who have been diagnosed with a specific, early-stage type of uterine cancer (well-differentiated endometrial cancer, Grade 1) confirmed by a procedure called a hysteroscopy, with no growth into the uterine wall. - People with a body mass index (BMI) of 30 or higher (classi...

Who might be able to join this trial: - People aged 12 years or older who have already started taking a medication called semaglutide (through any arrangement, such as early access programs, standard medical care, self-funded treatment, or special reimbursement), or whose doctor has decided to start them on semaglutide...

Who might be able to join this trial: - People between 18 and 75 years old who have obesity that is not caused by another medical condition, meeting at least one of the following measurements: a BMI of 25 or above, a waist measurement of 90 cm or more for men or 80 cm or more for women, or a waist-to-hip ratio of 0.9 o...

Who might be able to join this trial: - Adults between 18 and 65 years old who can understand instructions, follow study procedures, and are willing to sign a consent form. - People with a body mass index (BMI) between 29.0 and 37.0, meaning they are in the overweight to obese range. - People whose excess weight is sto...

Who might be able to join this trial: - Adults who are 18 years of age or older - People with a BMI of 35 kg/m² or higher - People who have at least a 10% chance of developing kidney failure requiring dialysis or transplant within 2 years, or who are already receiving dialysis Who may not be able to join: - People who...

**Who might be able to join this trial:** - Children and young people between the ages of 6 and 16 - Students attending a school that has given official approval to take part in the trial - Students for whom a signed consent form has been provided by the child or young person themselves - Students for whom a signed con...

Who might be able to join this trial: - People aged between 18 and 65 years who are having weight-loss (bariatric) surgery performed through small incisions (laparoscopic surgery) and who weigh more than 100 kg - People whose layer of fat just under the skin measures more than 5 cm thick, as measured by an ultrasound s...

**Who might be able to join this trial:** - Children and teenagers between the ages of 7 and 18 at the start of the trial. - People who have at least one blood sugar abnormality, such as prediabetes (blood sugar levels that are higher than normal but not yet in the diabetes range). - People who have at least one abnorm...

**Who might be able to join this trial:** - Adults between 18 and 65 years old who can understand instructions, follow the study procedures, and are willing to sign a consent form. - People who are overweight or obese with a body mass index (a measure of weight relative to height) between 29.0 and 40.0. - People who c...

Who might be able to join this trial: - People who are between 18 and 65 years old. - People with a body mass index (BMI) between 28 and 55 — BMI is a number calculated from height and weight, and the trial site can confirm where someone falls on this scale. - People who are willing to follow significant long-term chan...

**Who might be able to join this trial:** - Women who are pregnant and aged 18 or older - Women with a body mass index (BMI) of 18.5 or above (a standard measure of body weight relative to height) - Women who are currently pregnant without complications such as severe bleeding, diabetes during pregnancy, severe mornin...

Who might be able to join this trial: - People aged between 18 and 60 years old - People with a body mass index (a measure of body weight relative to height) above 25 kg/m² - People who score above 2.37 on a food craving questionnaire called the Food Craving Inventory (confirm with trial site) Who may not be able to j...

**Who might be able to join this trial:** - People aged 18 or older - People whose body mass index (BMI) is 30 or higher, OR whose BMI is 27 or higher and who also have at least one weight-related health condition (such as diabetes or pre-diabetes, high blood pressure, high cholesterol, sleep apnea, fatty liver disease...

**Who might be able to join this trial:** - The caregiver joining the trial must be 18 years of age or older, and speak English or Spanish - The caregiver must be the primary caregiver of a child who meets the following criteria: - The child is between 4 and 17 years old at the time of screening - The child has a BMI...

**Who might be able to join this trial:** - People who have been diagnosed with pre-diabetes within the last 6 months, confirmed by an accepted test - People aged 18 years or older - People with a Body Mass Index (BMI) between 25 and 40 (a measure of body weight relative to height) - People whose HbA1c (a blood sugar...

**Who might be able to join this trial:** - You are 18 years of age or older - Your heart is not pumping as strongly as normal (pumping 50% or less of its capacity), and you experience noticeable symptoms such as shortness of breath or tiredness during everyday activities but are still able to walk around - You are ei...

Who might be able to join this trial: - Children who are between 6 and 12 years old with a BMI above the 99th percentile based on the Cole criteria (2004), which is a standard chart used to measure weight relative to age and height in children Who may not be able to join: - Children who are younger than 6 or older tha...

**Who might be able to join this trial:** - Adults between 18 and 65 years of age - Men and women of any racial background - People with a body mass index (BMI) between 30 and 45 (a measure of weight relative to height that falls in the obese range) - People with elevated or high blood pressure — either pre-hypertensio...

Who might be able to join this trial: - People who are able to walk continuously for 15 minutes without using any walking aids (such as a cane or walker) and without help from another person. - People whose Body Mass Index (BMI) is greater than 25 and less than 45. - People who understand what the study involves, inclu...

Who might be able to join this trial: **For the adolescent:** - The adolescent lives with the biological parent or legal guardian who is also taking part in the trial - The adolescent identifies as Hispanic - The adolescent is between 12 and 15 years old - The adolescent has access to a smartphone - The adolescent doe...

Who might be able to join this trial: - People who are 18 years of age or older - People who have recently had a healthy pregnancy with one baby (not twins or more) - People who are between 6 and 16 weeks after giving birth at the time of joining the trial - People whose body mass index (a measure of body weight relati...

Who might be able to join this trial: - People who have gone through menopause - People who are overweight or obese - People who have a mostly inactive or sedentary lifestyle Who may not be able to join: - People currently using hormone therapy - People currently taking prescription medication for psychiatric or menta...

Who might be able to join this trial: - People with a body mass index (BMI) above 30 (a measure of body weight relative to height) - People who do not have any illness or condition that could affect their ability to move or perform physical tasks - People who are able to participate in and complete the tests involved i...

**Who might be able to join this trial:** - You are a man, or a woman who has been through menopause - You have a larger waist size (over 102 cm / about 40 inches for men, or over 88 cm / about 35 inches for women) - You have been found to have insulin resistance, meaning your body does not respond to insulin as well a...

Who might be able to join this trial: - People who self-identify as Black or of African descent - People who identify as female - People who are 18 years of age or older - People whose blood pressure reading is 130/85 or higher, or who have been diagnosed with high blood pressure, and/or whose body weight falls into th...

**Who might be able to join this trial:** The trial has five separate groups, each with different requirements: - **Group 1 – Lean, young adults:** People aged 18–35 with a BMI between 18.5 and 24.9 (maintained for at least 12 months) - **Group 2 – Overweight, young adults:** People aged 18–35 with a BMI of 28 or hig...

**Who might be able to join this trial:** - People between 18 and 70 years of age - People with a BMI above 19 kg/m² and a body weight under 250 kg - People who have had bariatric (weight loss) surgery and have since regained more than 10% of the weight they originally lost, with this regain happening between 1 and 5 y...

Who might be able to join this trial: - People who have signs and symptoms of heart failure, as defined by European heart health guidelines - People whose heart is pumping at 40% capacity or more (a measurement called ejection fraction) - People who have scored 5 or higher on a specific heart failure assessment tool ca...

**Who might be able to join this trial:** - People aged 18 or older, of any sex - People diagnosed within the past 15 years with breast cancer that has spread to the lymph nodes, is hormone receptor-positive (ER+ greater than 10%), and is HER2-negative, as defined by standard medical guidelines - People with cancer in...

Who might be able to join this trial: - Healthcare units such as NHS services and nursing homes that voluntarily choose to take part and provide direct patient care - Units that agree to follow evidence-based guidelines on hand hygiene, plus at least one of these topics: pain, urinary incontinence, obesity prevention,...

Who might be able to join this trial: - People who have been identified through a healthcare network or referred by a healthcare professional - People aged 18 or older - People living with obesity, meaning a BMI of 30 or above - People who understand and speak French Who may not be able to join: - People who do not wi...

**Who might be able to join this trial:** - People who are male and between 18 and 55 years old (inclusive) - People whose body mass index (BMI) falls between 24.0 and below 35.0 (a measure of body weight relative to height) - People whose blood sugar control levels are within a specific healthy range — specifically,...

Who might be able to join this trial: - People between 18 and 80 years of age with a BMI of 30 or higher (classified as obese) - Male patients with obesity who are scheduled for a planned (non-emergency) surgery that does not involve the chest Who may not be able to join: - Patients who need to be awake during the bre...

**Who might be able to join this trial:** - Adults between 18 and 65 years of age - People who have been diagnosed with a specific inherited kidney condition called ADPKD (Autosomal Dominant Polycystic Kidney Disease), confirmed using a standard set of diagnostic criteria - People with a body mass index (a measure of b...

Who might be able to join this trial: - People with a BMI of 30 or higher (which is generally classified as obesity) - People who are able to walk - People who are 18 years of age or older - People who are willing to participate as a volunteer Who may not be able to join: - People who are currently taking medication f...

**Who might be able to join this trial:** - People who have had non-specific lower back pain (back pain with no identified specific cause) lasting 3 months or more, and who have been referred back to a GP or primary care provider after seeing a hospital specialist - People with a body mass index (BMI) of 30 or above, O...

**Who might be able to join this trial:** - You are 45 years old or older at the time of signing the consent form - You have a Body Mass Index (BMI) of 30 or higher (which is generally considered obese) - Your doctor suspects you may have cardiovascular (heart and blood vessel) disease and has referred you for a cardia...

Who might be able to join this trial: - People who are already enrolled in the Miami-Dade Fit2Lead study. - People who are between 12 and 17 years old and live in Miami-Dade County. Who may not be able to join: - People who are not already enrolled in the Miami-Dade Fit2Lead study. - People who are younger than 12 or...

Who might be able to join this trial: - Parents or guardians who are 18 years of age or older - Children who are between 6 and 11 years old - Families who live within 5 miles of one of the targeted community centers Who may not be able to join: - Parents or children who have a medical or physical condition that makes...

**Who might be able to join this trial:** - A parent or guardian has given consent for their child to take part, and children aged 5 have verbally agreed to join - The child is between 3 and 5 years old and attends a Head Start program, and the caregiver taking part is that child's primary adult caregiver - The caregiv...

Who might be able to join this trial: - People with a Body Mass Index (BMI) between 25 and 39.9 (this covers the range generally described as overweight to moderately obese) - People aged between 18 and 60 years old - People who are proficient in the Spanish language - People who have access to the internet - People wh...

Who might be able to join this trial: - Men and pre-menopausal women between 18 and 45 years old - People with a body mass index (BMI) between 30.0 and 40.0 (a measure of body weight relative to height that the trial site can calculate) - Women who are not using hormonal birth control must agree to use an approved meth...

**Who might be able to join this trial:** - Men and women between 21 and 65 years old - People with a Body Mass Index (BMI) of 25 or higher (a standard measure of body weight relative to height) - People whose blood test results show a HOMA-IR score of 2.14 or higher — this is a measure of how well the body responds to...

Who might be able to join this trial: **For women who still have regular periods (premenopausal):** - Women between 18 and 45 years old - Women with regular menstrual cycles, meaning no missed periods in the past year and cycle lengths between 25 and 35 days **For women who have gone through menopause (postmenopausal...

**Who might be able to join this trial:** - People aged 18 to 70 years - People with a Body Mass Index (BMI) between 30 and 40 (a measure of weight relative to height that falls in the obese range) - People willing and able to understand and follow the study protocol - People who have been diagnosed with Crohn's diseas...

Who might be able to join this trial: - People who have been approved to receive weight-loss (bariatric) surgery at a hospital in Norway Who may not be able to join: - People who do not have sufficient skills in the language used in the trial to participate effectively - People who are not able to give informed consen...

Who might be able to join this trial: **For Veterans:** - Adults aged 18 or older - People who have been assigned to a VA primary care provider - People who have a body weight record showing a BMI of 30 or higher in the VA medical record within the past 16 weeks before joining - People who have a second valid weight m...

Who might be able to join this trial: - You have been rated by doctors as having a mild to moderate physical health status (known as ASA class II or III), meaning you have some health conditions but are not critically ill - Your Body Mass Index (BMI) is between 30 and 40, meaning you are classed as obese but not severe...

**Who might be able to join this trial:** - Your body mass index (BMI) is above 30 kg/m² and you have at least one health condition related to your weight (such as diabetes or high blood pressure), OR your BMI is above 35 kg/m² even without any weight-related health conditions **Who may not be able to join:** - You ha...

Who might be able to join this trial: - Adults aged 18 or older - People who have been clinically diagnosed with major depression - People with at least moderate depression severity, as measured by a standard depression questionnaire (BDI-II score of 20 or higher) - People with obesity, defined as a body mass index (BM...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) between 30 and 40 (or between 27.5 and 40 for people of Chinese or South Asian background), OR people with a BMI over 40 who are considered too high-risk for surgery or who do not wish to have surgery - People who have already tried standar...

**Who might be able to join this trial:** - People aged 65 years or older - People with a body mass index (BMI) between 30 and 45, or above 45 with a doctor's approval - People whose weight has stayed relatively stable (no more than 5% change) over the past 6 months - People who have been identified as having knee or...

Who might be able to join this trial: - People who are 18 years of age or older - People with a Body Mass Index (BMI) of 25 or higher, which is generally considered overweight Who may not be able to join: - People who have a physical or mental condition that prevents them from taking part in the study - People with a...

**Who might be able to join this trial:** - People who received a kidney transplant from a living or deceased donor between 3 and 5 months ago, and whose transplant doctor has given clearance to participate. - People of any gender, race, or ethnic background. - People aged 18 or older. - People with a Body Mass Index...

**Who might be able to join this trial:** - People of any gender, race, or ethnic background are welcome to participate. - For the Randomized Study: adults aged 18 up to (but not including) 60 years old. For the Observational Study: adults aged over 60 years old. - People who have recently been prescribed a weight-los...

Who might be able to join this trial: - People with a Body Mass Index (BMI) between 25 and 39.9 (a measure of body weight relative to height) - People aged between 18 and 60 years - People who are proficient in the Spanish language - People who are right-hand dominant (right-handed as their dominant side) Who may not...

**Who might be able to join this trial:** - People with a BMI of 30 or higher who have regained at least 25% of the weight they originally lost after sleeve gastrectomy surgery (where that surgery was initially considered successful) - People who had their sleeve gastrectomy surgery at least three years before joining...

Who might be able to join this trial: - People who have previously tried a structured weight loss program (including diet and exercise guidance for at least 3 months) without losing enough weight. - People aged 12 to under 18 whose BMI is at or above the 95th percentile for their age and sex, which is considered obesit...

**Who might be able to join this trial:** - You have tried at least one structured weight loss program (including diet and exercise counseling for at least 3 months) in the past, but did not lose enough weight. - Your BMI is at or above the 95th percentile for your age and sex (meaning you are in the category consider...

Who might be able to join this trial: - You are over 18 years old - You are living with obesity (any grade) or you are overweight and have at least one health condition related to your weight (such as diabetes or high blood pressure) (confirm with trial site) Who may not be able to join: - You have previously had weig...

**Who might be able to join this trial:** - Your waist measurement is 94 cm (37 inches) or more if you are male, or 80 cm (31.5 inches) or more if you are female, OR your BMI is above 25 kg/m² - Your body fat levels are above a certain amount, measured as a "fat mass index" — above 6 kg/m² for males and above 9 kg/m² f...

Who might be able to join this trial: - People between the ages of 20 and 60 years old, of any sex. - People with a general health status rated as ASA Class I to III, meaning those in good health or with mild to moderate health conditions (confirm with trial site). - People with a Body Mass Index (BMI) between 35 and 5...

**Who might be able to join this trial:** - One partner (the "target partner") must have a body mass index (BMI) of 25 or higher (or 23 or higher if they are Asian American) — this is a measure of body weight relative to height - The target partner must not have been diagnosed with type 1 or type 2 diabetes - The targ...

Who might be able to join this trial: - People who are biologically female - People with a BMI in the range of 19 to 24.99, or in the range of 30 to 40 - People who exercise at least 4 times per week for a total of at least 240 minutes per week, doing structured training such as running, cycling, triathlon, powerliftin...

**Who might be able to join this trial:** - You are between 20 and 75 years old and are covered by health insurance - You are a man with a waist circumference of 90 cm (about 35.5 inches) or more, or a woman with a waist circumference of 80 cm (about 31.5 inches) or more - Your fasting blood sugar is 100 mg/dL or highe...

**Who might be able to join this trial:** - You are over 18 years old - Your Body Mass Index (BMI, a measure of body weight relative to height) is above 30, which is generally considered obese - You have not yet had a heart attack, stroke, or other cardiovascular (heart and blood vessel) event — meaning you are being s...

Who might be able to join this trial: - Students from Kindergarten through 5th grade (and Pre-Kindergarten where applicable) who eat lunch in the school cafeteria on the days when observations are taking place are eligible for the lunchroom observation part of the study. - Students who are enrolled in the study while i...

Who might be able to join this trial: - Schools located in the Madrid Region or Catalonia, Spain - Public or charter (partially state-funded) schools - Schools that include grades 1 through 6 and have at least one 1st grade classroom - Schools that have an on-site canteen (school cafeteria) - Children who are currently...

**Who might be able to join this trial:** - The baby must be a single birth (not a twin or multiple) and be between 3 and 9 weeks old. - The baby must have been born at full term (at or after 37 weeks of pregnancy). - The mother must be at least 18 years old. - Any other caregiver involved must also be at least 18 year...

**Who might be able to join this trial:** - People of any ethnicity between the ages of 20 and 60 years old - People with a Body Mass Index (BMI) of 30 or higher (a measure of body weight relative to height) - People with no history of neurological or psychiatric conditions, as confirmed through medical history and scr...

Who might be able to join this trial: **For people with Prader-Willi syndrome (PWS):** - People who are 18 years of age or older - People who have a confirmed diagnosis of Prader-Willi syndrome with an identified genetic type - People whose cognitive testing (a standardised thinking and reasoning assessment called WAI...

**Who might be able to join this trial:** - Adults who are already enrolled in the multidisciplinary weight loss surgery program at UK HealthCare Weight Loss Surgery Clinic and are scheduled to have sleeve gastrectomy or gastric bypass surgery (laparoscopic or robotic) - People with a BMI of 40 or higher who also have...

Who might be able to join this trial: - People who are overweight or obese, meaning their Body Mass Index (BMI) is 25 or higher - People who live a mostly sedentary (inactive) lifestyle, based on a standard activity level measurement (confirm with trial site) - People who currently do less than 150 minutes per week of...

Who might be able to join this trial: - People who identify as Black or African American (this applies to the main participant) - Main participants with a BMI of 30 or higher; family/partner participants with a BMI of 27.5 or higher - People who have a family member or partner who is also willing to join the study, and...

**Who might be able to join this trial:** - Women who carry excess weight around their midsection (central obesity) - Women between 25 and 40 years of age - Women with a Body Mass Index (BMI) between 30 and 35 (a measure of body weight relative to height) - Women with a waist measurement greater than 88 cm, which indi...

Who might be able to join this trial: - People with a BMI between 30 and 45 kg/m² - Both men and women are eligible - People between 18 and 65 years old - People who exercise less than 2 hours per week of moderate, structured, intentional physical activity (ranging from not exercising at all to being only lightly activ...

Who might be able to join this trial: - You are between 20 and 60 years old - Your body weight falls into one of two specific ranges: either a healthy/normal weight (BMI 18.5–25) or obese (BMI above 30) - Women who could become pregnant must be using hormonal birth control (such as the pill or a hormonal coil) Who may...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) between 30 and 45 — this is a measure of body weight relative to height. - People who are between 30 and 60 years old at the time of joining the trial. - People whose arteries show signs of stiffening, measured during a screening test using...

**Who might be able to join this trial:** - The mother (or primary caregiver) must be 18 years of age or older - The mother must speak and read/write Bengali or Hindi/Urdu - The mother must have been born in a South Asian country - The mother must be the main caregiver for the child - The child must be between 12 and...

Who might be able to join this trial: - People who are proficient in English - Young people between the ages of 11 and 14 - Young people whose BMI is at or above the 85th percentile for their age and sex (a measure used to assess body weight relative to other children of the same age and sex) - People who have access t...

**Who might be able to join this trial:** - People aged between 18 and 60 years old - People with a Body Mass Index (BMI) between 25 and 34.9 (a measure of body weight relative to height — confirm the exact calculation with the trial site) - People of any biological sex - People who are able to follow the study schedul...

Who might be able to join this trial: - People who are willing and able to give their informed consent to take part in the study - People aged 18 years or older - People who have been diagnosed with a specific type of heart failure called HFpEF by an experienced heart specialist, or who have signs and symptoms of heart...

Who might be able to join this trial: - Men or women between 18 and 65 years old who have obesity, meaning a BMI (body mass index) above 30 kg/m² Who may not be able to join: - People whose weight has changed by more than 3% in the past 3 months - People who have previously had weight-loss surgery or a weight-loss pro...

**Who might be able to join this trial:** - People aged between 21 and 50 years old - People with a BMI between 25 and 30 - People who are able to have their height, weight, waist, hip circumference, and body composition measured during the study - People who are able to provide saliva samples - People who are able to...

Who might be able to join this trial: - People aged 18 to 55 years old at the time of signing the consent form, of any gender. - People with a Body Mass Index (BMI) between 27 and 45 kg/m² (a measure of body weight relative to height). - Male participants with a waist measurement of 90 cm or more, or female participant...

Who might be able to join this trial: - People with a BMI over 30 (classified as obese) who have been diagnosed with a gynaecological cancer - People whose blood test results have been optimised before surgery, including healthy levels of red blood cells, white blood cells, and platelets - People who received chemother...

**Who might be able to join this trial:** **Case group (people with breast cancer):** - People who are biologically female - People who have gone through natural menopause (periods stopped on their own, without surgical removal of the ovaries) for at least 1 year - People who have used hormone replacement therapy (HRT...

**Who might be able to join this trial:** - You are over 18 years old - Your body mass index (BMI) is over 30 (a measure of body weight relative to height — confirm with trial site if unsure of your BMI) - You have regular access to the internet, as sessions are held over Zoom video calls - If required during the scree...

Who might be able to join this trial: - Your body mass index (BMI) is between 40 and 50 (a measure of weight relative to height that indicates severe obesity) - You have been assessed as suitable for a type of weight-loss surgery that combines restriction and malabsorption (confirm with trial site) Who may not be able...

**Who might be able to join this trial:** - Your Body Mass Index (BMI) is between 30 and 40, or 27.5 and 40 if you are Chinese or South Asian (BMI is a measure based on your height and weight) - Your BMI is above 40 and you are either considered too high-risk for weight-loss surgery, or you do not wish to have surgery...

**Who might be able to join this trial:** - People who have signed a consent form agreeing to take part in the study - People aged between 18 and 60 years old - People with a Body Mass Index (a measure of body weight relative to height) between 30 and 50 - People who can read and speak German well enough to understand...

Who might be able to join this trial: - People who are between 18 and 65 years old - People who are Italian nationals - People with a Body Mass Index (BMI) of 35 or higher (this is a measure of body weight relative to height — confirm with the trial site if unsure how to calculate this) Who may not be able to join: -...

**Who might be able to join this trial:** - People who are in a normal heart rhythm (called sinus rhythm) at the time of joining the trial - People aged 18 to 80 years old - People with a Body Mass Index (BMI) between 27 and 60 - People who have been diagnosed with atrial fibrillation (an irregular heartbeat), confirm...

**Who might be able to join this trial:** - People who are able to give written consent before any study procedures begin. - People who have been referred to the LEAF clinic by their doctor, or who have referred themselves to the LEAF clinic for weight loss, and who the LEAF clinic team has determined are appropriate...

Who might be able to join this trial: - Men and postmenopausal women who are 50 years of age or older - People with a Body Mass Index (BMI) of 30 or above (a measure of body weight relative to height) - People whose blood sugar control (measured by a test called HbA1c) is below 6.5% and who are not currently taking any...

Who might be able to join this trial: - You are 60 years old or older - You are male or female and live independently in the community (not in a care facility) - You currently live in Luxembourg - Your body weight falls in the normal or overweight range (your BMI is between 18.5 and 30 kg/m²) (confirm with trial site i...

**Who might be able to join this trial:** - People with a Body Mass Index (BMI) between 27 and 45, meaning they are overweight or obese - People who have been diagnosed with a liver condition, specifically fatty liver disease (MASLD/NAFLD), liver inflammation related to metabolic issues (MASH), cirrhosis, or an early-t...

**Who might be able to join this trial:** - People aged between 65 and 85 years old - People who have been diagnosed with stable heart failure where the heart is either pumping normally (preserved function) or pumping with reduced strength (confirm with trial site for specific measurements) - People whose heart failur...

Who might be able to join this trial: - You are 18 years old or older and are scheduled to have a type of weight loss surgery called One Anastomosis Gastric Bypass (OAGB) (confirm with trial site) Who may not be able to join: - You are under 18 years old, are pregnant, or are unable to make your own decisions about ta...

Who might be able to join this trial: - People with a body mass index (BMI) of 30 or higher (this is a standard weight-to-height measurement) - People scheduled to have their first total hip replacement surgery on one hip using a specific surgical approach called the Direct Anterior Approach (DAA) - People undergoing a...

Who might be able to join this trial: - You are between 18 and 75 years old - You have obesity, meaning your BMI is between 30 and 50 if you are non-Asian, or between 27.5 and 50 if you identify as Asian - You weigh less than 400 pounds - You currently receive care at a participating community health clinic, or are wil...

Who might be able to join this trial: **Part A (Healthy volunteers):** - Adults aged 18 to 60 years, male or female - Body mass index (a measure of weight relative to height) between 28 and 35, which has been stable (within about 5%) for the past 3 to 6 months — or up to 40 for certain expanded groups - Generally heal...

Who might be able to join this trial: - Families who have moved to Canada within the last 10 years and have at least one child between the ages of 5 and 11 (up to but not including age 12) living in Hamilton, Ontario. - At least one parent or guardian in the family must have been born outside of Canada and must have be...

**Who might be able to join this trial:** - People who are between 18 and 39 years old at the time of signing up for the trial - People who were first diagnosed with an invasive cancer between the ages of 15 and 39 (based on self-report) - People who were diagnosed no more than 10 years ago and have no signs of the ca...

Who might be able to join this trial: - Children, teenagers, and young adults from birth up to age 24, along with their close family members (such as parents and siblings) - Adults aged 25 or older who are either pregnant or trying to become pregnant - People who live in Louisiana (based on self-report) - People who ar...

Who might be able to join this trial: - People who are right-handed and have been diagnosed with obesity - People who are currently receiving rehabilitation treatment at the Istituto Auxologico Who may not be able to join: - People who have been diagnosed with neurological conditions, neurodevelopmental conditions (su...

**Who might be able to join this trial:** - You are a woman aged between 18 and 64 years old - Your Body Mass Index (BMI) is between 40 and 50 (a measure of weight relative to height) - You are scheduled to have weight-loss (bariatric) surgery 10 to 12 weeks after the nutrition programme begins - You currently spread y...

**Who might be able to join this trial:** - People aged between 18 and 70 years old, of any gender - People who are having bariatric or metabolic (weight-loss) surgery for the first time, with a body weight that falls into one of these categories: a BMI of 40 or above; OR a BMI of 35 or above with at least one related...

**Who might be able to join this trial:** - People who are already part of the RESONANCE research cohort (an existing group of study participants) and who will be between 7 and 12 years old during the study period - People in that group who have no food allergies **Who may not be able to join:** - People who were expo...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form - People with a BMI of 28 or higher - People whose heart failure symptoms fall into a moderate category (NYHA Class II or III) (confirm with trial site) - People who have not been hospitalised due to heart failu...

**Who might be able to join this trial:** - People who have been on a breathing machine (mechanical ventilator) for at least 48 hours - People who are on a ventilator setting that allows them to take some breaths on their own, with the machine providing support, and where the breath size and pressure settings fall wit...

Who might be able to join this trial: - Women who are overweight or obese, with a BMI (body mass index) between 25 and 35 kg/m² Who may not be able to join: - Women who are currently using contraceptives (birth control) - Women who have gone through menopause - Women who have an irregular menstrual cycle - Women who h...

**Who might be able to join this trial:** - Adults (men and women) who are older than 20 years of age - People who are already scheduled for a surgical procedure to remove fat tissue from the body - People who have given signed written consent to take part in the study **Who may not be able to join:** - People who hav...

Who might be able to join this trial: - People who have severe or morbid obesity, meaning a BMI over 35 or 40 kg/m², and who meet current medical guidelines for bariatric (weight-loss) surgery. - People who show signs of reduced control over their eating habits, as measured by a specific questionnaire called the Eating...

Who might be able to join this trial: - People with a body mass index (BMI) in either the 20–25 range (considered a healthy weight) or the 30–37 range (considered obese) - People in the obese BMI range who also have a waist-to-hip ratio of 0.95 or higher (males) or 0.90 or higher (females), which is a measurement compa...

**Who might be able to join this trial:** *(This trial defines eligibility based on activity level — please confirm the specific requirements for each group with the trial site.)* - People who fit into either an "inactive" group or an "active" group based on how often they currently exercise (confirm with trial site...

**Who might be able to join this trial:** - Adults aged 18 or older. - People with a body mass index (BMI) of 28 or above, OR a BMI between 24 and 28 who also have at least one weight-related health condition, such as: high blood pressure or use of blood pressure medication; abnormal cholesterol or triglyceride levels...

**Who might be able to join this trial:** - Men and post-menopausal women between the ages of 30 and 75 - People with a body mass index (a measure of body weight relative to height) between 27 and 40 - People with a waist measurement greater than 102 cm (for men) or 88 cm (for women) - People whose weight has stayed ro...

**Who might be able to join this trial:** - People who are 18 years of age or older - People with a BMI of 25 or higher (or 23 or higher if the person is of Asian background) - People whose blood sugar test results fall within the prediabetes range, such as a fasting blood sugar level between 110–125 mg/dL or an A1C le...

**Who might be able to join this trial:** - People who are willing and able to give voluntary, signed, and dated consent to take part. - People who are in good general health based on their medical history. - People aged between 18 and 65 years (inclusive). - People with a Body Mass Index (BMI) between 25.0 and 40.0 (i...

Who might be able to join this trial: - People aged between 18 and 60 years old - People with a body mass index (BMI) between 28 and 40 (a measure of body weight relative to height — confirm with trial site if unsure of your BMI) - Women with a waist circumference of 88 cm (35 inches) or more, or men with a waist circu...