Type 1 Diabetes

Who might be able to join this trial: - You have Type 1 diabetes and have been taking insulin for at least 12 months - You are planning to become pregnant and your recent blood sugar control test (HbA1c) shows a result of 9.0% or lower, OR - You are already pregnant with one baby, between 8 and 12 weeks along, and your...

Who might be able to join this trial: - You must be 7 years old or older at the time of screening - You must have been using an insulin pump for at least 3 months - You must be experienced with continuous glucose monitoring, meaning you can insert and change the sensor yourself, recharge the transmitter, and read your...

**Who might be able to join this trial:** - You are a woman aged 18 or older at the time of signing the consent form - You have been diagnosed with type 1 diabetes for at least 1 year before your screening appointment - You have been using daily insulin injections, an insulin pump, or inhaled insulin for at least 90 da...

Who might be able to join this trial: - People aged 2 to 45 years old who have a close family member (such as a child, parent, or sibling) with type 1 diabetes - People aged 2 to 20 years old who have an extended family member (such as a cousin, niece, nephew, aunt, uncle, grandparent, or half-sibling) with type 1 diab...

**Who might be able to join this trial:** - Adults aged 18 to 65 years old at the time of the first dose. - People who are generally healthy, with no known ongoing or long-term medical conditions, and no history of autoimmune diseases, as assessed by the study doctor. - People with a body mass index (BMI) between 18 a...

**Who might be able to join this trial:** - People who have been clinically diagnosed with type 1 diabetes - People whose diabetes has lasted 10 years or more - People who score 4 or higher on either the Gold Score or Clarke Score, which are tools used to assess whether someone has reduced awareness of low blood sugar...

**Who might be able to join this trial:** - You have a Body Mass Index (BMI) between 30 and 50, and you weigh no more than 159 kg (350 lbs) at the time of screening - You have tried to lose weight through lifestyle changes (such as diet or exercise) at least once before, without success - You have no significant health...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes for at least 1 year before the screening visit. - People who have been using a daily long-acting insulin injection plus a fast-acting insulin injection regimen for at least 6 months before the screening visit. - People whos...

Who might be able to join this trial: - People aged 1 to 25 years old at the time of signing the consent form - People who have been diagnosed with Stage 3 Type 1 Diabetes (T1D) according to 2025 American Diabetes Association criteria - People who are able to start the study treatment within 8 weeks (56 days) of their...

Who might be able to join this trial: - People aged 15 to 40 years old at the time of joining Part A of the trial, or aged 5 to 40 years old for Part B. - People who weigh at least 16 kg at the time of joining. - People who have been diagnosed with Type 1 diabetes within the last 100 days (including those initially mi...

Who might be able to join this trial: - People who have had at least two diabetes-related autoantibodies (proteins the immune system makes that can signal early type 1 diabetes) detected on at least two separate occasions, including one test at or before the screening visit - People who have been identified as having S...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes within the last 100 days before starting the study - People who have at least one autoantibody linked to diabetes, found during a screening blood test - People whose pancreas is still producing some insulin, shown by a speci...

**Who might be able to join this trial:** - People with Type 1 diabetes (T1D) who are aged 7 to 85 years, or people with insulin-requiring Type 2 diabetes (T2D) who are aged 18 to 85 years. - People who have had a confirmed diagnosis of T1D for at least 6 months, or insulin-requiring T2D for at least 1 year, as shown...

**Who might be able to join this trial:** - Anyone aged 18 or older, of any gender identity, regardless of sex assigned at birth - People with a Body Mass Index (BMI) of 35 or higher (a measure of body weight relative to height) - People **without** type 2 diabetes, meaning they have no history of it and a blood sugar...

**Who might be able to join this trial:** - You have chronic kidney disease that is believed to be caused by Type 1 or Type 2 diabetes - Your kidney function falls within a specific range, based on blood test results measuring creatinine levels or an estimated kidney function score (confirm with trial site for your exa...

**Who might be able to join this trial:** - You are 18 years of age or older - Your cancer can be measured on scans, as defined by a standard medical measurement system called RECIST v1.1 (confirm with trial site) - You are generally able to carry out daily activities with little or no limitation — rated 0 or 1 on a st...

Who might be able to join this trial: - People who have been clinically diagnosed with diabetes mellitus, based on American Diabetes Association (ADA) standards - People between the ages of 18 and 69 - People whose diabetes diagnosis was made less than 12 months ago - People in the control group: those who have been co...

Who might be able to join this trial: - People who are older than 18 years of age - People who have been diagnosed with diabetes mellitus based on standard diagnostic guidelines - People who are willing and able to provide informed consent to participate Who may not be able to join: - People who have diabetes that dev...

Who might be able to join this trial: - People aged 18 to 68 years, of any gender. - People who are able to give written consent and follow the study's procedures. - People with a clinical history consistent with Type 1 diabetes that was diagnosed before age 40, who have been on insulin for more than 5 years, and where...

Who might be able to join this trial: - You are between 18 and 70 years old (male or female). - You are able to give written consent and willing to follow the study procedures. - You have Type 1 diabetes that started before age 40, have been on insulin for at least 5 years, have very little to no natural insulin produc...

**Who might be able to join this trial:** - Adults between 18 and 70 years of age (male or female) - People who are able to give written consent to participate - People who are mentally stable and able to follow the study procedures - People who are currently taking anti-rejection (immunosuppressive) medications, or wh...

Who might be able to join this trial: - People who previously took part in one of these specific parent studies: 2000/0329; 2000/0196; 2004/0205; 2000/0024; 2006/0200; 2006/0508; or 2006/0210 - People who have a working pancreatic islet transplant (the transplanted tissue is still functioning and has not failed) and ar...

Who might be able to join this trial: - People who have had at least one islet-alone transplant in the past (this means a transplant of insulin-producing cells only, not done alongside any other organ transplant) Who may not be able to join: - People who are not able to provide written consent to take part in the stud...

"Who might be able to join this trial: - People who have been recently diagnosed with type 1 diabetes and are being treated with insulin. - People who are willing to give written consent to take part in the study. - People who have no other medical conditions and are not taking any medications other than insulin. Who...

Who might be able to join this trial: - People who have previously taken part in a type 1 diabetes study that was approved by the Immune Tolerance Network (ITN) executive committee. - People who are able to sign a consent form agreeing to take part (for children, a parent or guardian may sign on their behalf, with the...

**Who might be able to join this trial:** *Eye-related criteria (for the eye being treated):* - People who have at least one eye with very severe vision loss, ranging from only being able to see a hand waving in front of them down to no light perception at all. - People whose eye being treated still has its natural le...

Who might be able to join this trial: - You have Type 1 diabetes and are between 18 and 50 years old (the trial is looking for 32 men and 32 women). - Your recent blood sugar control test (HbA1c) result is below 11.0%. - You have not been diagnosed with diabetes-related complications such as eye disease, nerve damage,...

"Who might be able to join this trial: - The patient must be aged up to 6 weeks old. - A custodial parent or guardian must have provided written consent on the patient's behalf. Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site). Important: Always v...

**Who might be able to join this trial:** - People diagnosed with Stage III or Stage IV sarcoma, or sarcoma that has come back after previous treatment - People aged 18 to 65 years old at the time of joining the trial - People who have waited at least 4 weeks since their last chemotherapy or radiation treatment, and a...

Who might be able to join this trial: **Study 1 – Early-onset Type 1 Diabetes group (EET1D):** - People aged 0 to 70 years who have been clinically diagnosed with diabetes within the last 24 months, with evidence meeting standard diabetes diagnostic guidelines - People whose genetic test results rule out a non-immune-...

Who might be able to join this trial: - People who have had Type 1 diabetes for at least 12 months - People whose average blood sugar levels (measured by a test called HbA1c) have stayed at 7.5% or higher, even after receiving the best available diabetes education and care - People who experience repeated episodes of d...

**Who might be able to join this trial:** This trial has four separate groups. People may be considered for one of the following groups: **Control Group (no diabetes):** - Adults over 18 years old who have given oral consent - People who do not have diabetes - People with a fasting blood sugar level below 6.10 mmol/L...

Who might be able to join this trial: **For families:** - At least one close blood relative (parent, sibling, or child) in the family has been diagnosed with type 1 diabetes - The family member with type 1 diabetes was diagnosed before the age of 39 - Family members taking part must be at least 2 years old **For cont...

**Who might be able to join this trial:** - People who have had Type 1 diabetes for at least 1 year - People aged 18 to 40 years - People who have reached at least Tanner stage IV of physical development (a measure of physical maturity — confirm with trial site if unsure) - People with a body mass index (BMI) between...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes - People who are currently living in Canada Who may not be able to join: - People who have type 2 diabetes - People who have gestational diabetes (a form of diabetes that develops during pregnancy) Important: Always verify eli...

**Who might be able to join this trial:** - You are between 18 and 68 years old - You have been diagnosed with Type 1 diabetes for at least 5 years, confirmed by a specific blood test showing very low insulin production (confirm with trial site) - Your blood sugar levels are unstable, meaning you experience low blood...

**Who might be able to join this trial:** - Children who have been diagnosed with Type 1 diabetes and also have a known genetic problem affecting their immune system - The Type 1 diabetes diagnosis must be confirmed by blood sugar tests, tests of how the insulin-producing cells are working, and tests looking for certa...

**Who might be able to join this trial:** - People who are over 18 years old - People who have been diagnosed with Type 1 diabetes - People who are in good general health - People whose fasting C-peptide level (a marker of insulin production) is below 0.7 ng/ml - People whose blood sugar control (measured by HbA1c) is...

Who might be able to join this trial: - People who have been diagnosed with Type 1 Diabetes. - People who have had diabetes for more than 5 years. - People whose average blood sugar level (measured by a blood test called HbA1c) is 9% or below. - People who are able to understand and agree to the study rules by signing...

**Who might be able to join this trial:** - You are between 18 and 25 years old - You have had diabetes treated with insulin for more than 12 months, either using daily injections or an insulin pump - At least one of the following applies to you: your long-term blood sugar level (HbA1c) is above a certain high threshol...

Who might be able to join this trial: - A parent or legal guardian who has custody of the child must give their written agreement for the child to take part in the trial. Who may not be able to join: - No specific exclusion criteria were listed in the information provided (confirm with trial site). Important: Always...

Who might be able to join this trial: - You have been diagnosed with Type 1 Diabetes based on World Health Organization standards - You (or a family member on your behalf) are willing and able to sign a consent form agreeing to take part - You own a smartphone and are able to use WeChat or other apps Who may not be ab...

**Who might be able to join this trial:** - People who have had Type 1 diabetes for at least 1 year - People aged 18 to 40 years - People who have reached at least Tanner stage IV of physical maturity (a measure of physical development — confirm with trial site if unsure) - People with a body mass index (BMI) between...

**Who might be able to join this trial:** **People with diabetes-related kidney disease (DKD) may be eligible if:** - A doctor has diagnosed them with type 1 or type 2 diabetes, confirmed by a blood sugar or HbA1c test, use of diabetes medication, or a formal medical diagnosis code - They have signs of lasting kidney...

**Who might be able to join this trial:** - You have been diagnosed with diabetes mellitus - You are male or female of any age, though the trial is especially focused on children and young people - You (and any legal guardians or representatives, if applicable) are willing and able to give your consent to take part bef...

Who might be able to join this trial: - Men and women who have not yet gone through menopause - People of any racial background - People who have been diagnosed with insulin-dependent type 1 diabetes (for the patient group of the trial) Who may not be able to join: - People who have been diagnosed with liver, heart, o...

Who might be able to join this trial: - People who have been clinically diagnosed with type 1 diabetes. - People under 18 years old whose parent or guardian is willing to provide consent. - People who can read and understand English. - People who are currently living in the United States. Who may not be able to join:...

**Who might be able to join this trial:** - People aged 6 years or older - People who were diagnosed with diabetes between the ages of 1 and 35 years old - People who started insulin treatment within the first 12 months after being diagnosed with diabetes - People who are enrolled in the French social security scheme -...

Who might be able to join this trial: - Adults aged 18 or older - People who have received a kidney transplant within the past year, with the transplanted kidney still working at an acceptable level - People who have Type 2 Diabetes and are currently using insulin - People who have access to a home wi-fi connection Wh...

**Who might be able to join this trial:** - People who have a clinical history of Type 1 Diabetes (T1D) and have been dependent on insulin for more than 5 years - People who have had at least two serious low blood sugar episodes (severe hypoglycemia) that were recorded in the 12 months before joining the trial - People...

Who might be able to join this trial: - You speak Spanish or English - You have been diagnosed with Type 1 diabetes - Your recent blood sugar control test (called HbA1c), taken within the last 90 days, showed a result between 7.0% and 12.5% - You have screened positive for diabetes distress, meaning you are experiencin...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes within the past 12 months, based on specific Canadian diabetes guidelines. - People aged 7 years and older (at the main trial site), or between 7 and 17 years old (at other participating sites). **Who may not be able to jo...

**Who might be able to join this trial:** This trial has several different groups, and the criteria differ depending on which group a person may be considered for: **Recently diagnosed group:** - Children aged between 1 and 15 years old - Recently diagnosed with type 1 diabetes, based on recognised international crit...

Who might be able to join this trial: - You have Type 1 diabetes and have been using an automated insulin delivery system, or multiple daily insulin injections/insulin pump together with a continuous glucose monitor, for more than 6 months - You are between 12 and 25 years old - Your most recent HbA1c blood sugar avera...

Who might be able to join this trial: - People aged 18 years or older - Cancer patients who are being treated with a type of therapy that works by boosting the immune system (known as immune checkpoint inhibitor therapy) - People who have a primary autoimmune or autoinflammatory condition — meaning their immune system...

Who might be able to join this trial: - People who have Type 1 diabetes, meaning they have high blood sugar and have been on long-term insulin treatment started within 6 months of their symptoms beginning, and/or have at least one specific diabetes-related antibody detected in their blood - People who have another form...

**Who might be able to join this trial:** - People (men and women) who have been diagnosed with Type 1 Diabetes - People who use an insulin pump to manage their diabetes **Who may not be able to join:** - People who have been hospitalised for diabetes-related problems (such as dangerously high or low blood sugar episo...

**Who might be able to join this trial:** - You have had Type 1 diabetes for more than 12 months - You are between 6 and 18 years old at the time of joining the trial - You are a patient at the Pediatric Diabetes outpatient clinic at Steno Diabetes Center Copenhagen - You can speak and read Danish well enough to unders...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes for at least one year - People who have regular menstrual cycles - People who are currently taking a single-hormone type of birth control pill (called monophasic oral contraceptives) - People who live in Edmonton, Alberta and ar...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes for at least one year - People who are post-menopausal (at least one year since their last period), or who have had their uterus and both ovaries surgically removed - People who are able to do both aerobic exercise (such as...

**Who might be able to join this trial:** - Women who have been diagnosed with type 1 diabetes for at least one year - People whose last menstrual period was at least 12 months ago (i.e., have gone through menopause) - People who are physically able and willing to do resistance exercise (such as weight training) - Peop...

**Who might be able to join this trial:** - Women aged 18 to 50 who live in Canada - People who have been diagnosed with type 1 diabetes or a related condition called latent autoimmune diabetes in adults (LADA) for at least one year - People who have been using an insulin pump, multiple daily insulin injections, or an...

Who might be able to join this trial: - People with a body mass index (BMI) between 25 and 30 (considered slightly overweight) - People who have been diagnosed with type 1 diabetes, or people who do not have any diabetes and are otherwise healthy Who may not be able to join: - People who currently use nicotine in any...

Who might be able to join this trial: - People who have been diagnosed with Type 1 or Type 2 diabetes - People who are 18 years of age or older - People who can speak and understand English - People who have been released directly from one of five prisons in Connecticut to supervised community housing or parole Who ma...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes and have a history of severe low blood sugar episodes and/or are unable to feel or notice when their blood sugar drops dangerously low - People who have had a severe low blood sugar episode where their blood sugar dropped below...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes according to specific World Health Organization guidelines from 1999 - People who have needed insulin since their diabetes was first diagnosed - People who have had type 1 diabetes for 10 years or longer - People who are able to...

Who might be able to join this trial: - Young people aged 11 to 18 who have Type 1 diabetes and are overweight or obese - Young people aged 11 to 18 who have Type 1 diabetes and have a lean body type Who may not be able to join: - People who have a rare inherited form of diabetes (monogenic diabetes) or Type 2 diabete...

**Who might be able to join this trial:** - Children and young people living in Uganda, between 4 and 26 years old at the start of the study - People who have been diagnosed with Type 1 diabetes based on clinical assessment, for at least 12 months before the study begins - People who are currently using insulin to mana...

**Who might be able to join this trial:** - You have Type 1 diabetes that was diagnosed at least 3 years ago, and you are at least 11 years old or have started puberty - You have been diagnosed with Type 2 diabetes - You are between 8 and 21 years old, have Type 1 or Type 2 diabetes, and have already been diagnosed wit...

**Who might be able to join this trial:** - People who have had Type 1 diabetes for more than 12 months - People between 18 and 65 years old - People whose most recent HbA1c blood sugar reading (a 3-month average of blood sugar levels) falls between 6.5% and 9% **Who may not be able to join:** - People who have Type 2...

**Who might be able to join this trial:** - You are between 18 and 80 years old - You have had Type 1 diabetes for at least 5 years - Your urine test shows a certain level of protein (albumin) in your urine, within a specific range — your doctor can check this (confirm with trial site) - Your kidneys are working at a r...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes at any point in their life, where the diagnosis was made by a specialist doctor. - People who were diagnosed with diabetes before the age of 15, were not overweight or obese at the time of diagnosis, have had a serious epis...

**Who might be able to join this trial:** - You have agreed to take part and signed a consent form (or assent form if applicable) - You have Type 1 diabetes (adults or children are welcome) — OR — - You are an adult with Type 2 diabetes — OR — - You have tested positive for certain diabetes-related antibodies (insulin,...

Who might be able to join this trial: - People between 18 and 80 years old (men and women). - People who have been diagnosed with diabetes, of any type. - People who have not already been diagnosed with diabetic nerve damage in their feet or legs at the time of joining. Who may not be able to join: - People who have h...

Who might be able to join this trial: - People who are currently in hospital with a newly diagnosed diagnosis of type 1 diabetes. - People whose parent or legal guardian is able to provide written consent to participate. Who may not be able to join: - People who have already received a flu vaccine during the current f...

**Who might be able to join this trial:** **For people with fulminant type 1 diabetes:** - People who developed dangerous levels of ketones in their blood (a serious complication) very soon after their blood sugar first became high - People whose blood sugar was at or above 16.0 mmol/L and whose HbA1c (a 3-month avera...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes and have tested positive for certain antibodies related to the condition (antibodies against islets, insulin, IA2, GAD65, or ZnT8) - People who use an insulin pump (a small device that delivers insulin continuously under the...

**Who might be able to join this trial:** - You must be able to understand the study and sign a consent form agreeing to take part - You must be between 18 and 35 years old - You must have been diagnosed with Type 1 diabetes within the last year, and still have some remaining insulin-producing function shown by a spec...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes (an autoimmune condition where the body attacks the cells that make insulin) for at least one year, confirmed through blood sugar tests, medical records, or a doctor's assessment - Adults aged 18 to 89 years old - People wh...

**Who might be able to join this trial:** - People who have been clinically diagnosed with type 1 diabetes (based on World Health Organization criteria) for at least one year - People who have been using insulin for at least six months - People aged 18 to 40 years old - People whose HbA1c (a measure of average blood s...

Who might be able to join this trial: - People who are 18 years of age or older at the time they enter the study - People whose medical records, including prescriptions, diagnoses, and medical history, are available for at least 12 months before their entry into the study - People who have been diagnosed with type 2 di...

Who might be able to join this trial: - Women aged 18 years or older who have a pre-existing diabetes diagnosis, including type 1 diabetes, type 2 diabetes, or other forms such as MODY (a rare inherited form of diabetes) - Partners (aged 18 or older) of women who meet the above criteria - Children born to women who mee...

Who might be able to join this trial: **For patients:** - People who have diabetes and are receiving treatment within the Region Västra Götaland healthcare region in Sweden. - People who can understand spoken and written Swedish. **For healthcare professionals:** - Healthcare professionals whose work involves caring...

"Who might be able to join this trial: - People who have given their signed consent to participate in the trial - People who have been diagnosed with Type 1 Diabetes Who may not be able to join: - No specific exclusion criteria were listed in the available information (confirm with trial site) Important: Always verif...

**Who might be able to join this trial:** - You have been living with Type 1 diabetes for at least 6 months - You are between 18 and 64 years old - You speak English or Spanish - You have been diagnosed with an anxiety disorder or a depressive mood disorder, confirmed through a structured interview as part of the study...

"Who might be able to join this trial: - Children born to women who took part in the CONCEPTT clinical trial at one of the selected participating sites Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with the...

**Who might be able to join this trial:** - Adults aged 18 or older who are seen as outpatients (not currently admitted to hospital) - People who have been diagnosed with type 1 diabetes by a doctor - People who manage their diabetes using an insulin pump or by taking multiple insulin injections each day - People whos...

**Who might be able to join this trial:** - People who have had type 1 diabetes for at least 5 years - People who are at risk of low blood sugar levels during the night — either shown by a continuous glucose monitor (CGM) recording blood sugar dropping very low (below 54 mg/dL) for at least 1% of the time over the past...

**Who might be able to join this trial:** - People who have been clinically diagnosed with insulin-dependent type 1 diabetes - People who have tested positive for at least one specific diabetes-related antibody (these are markers in the blood that indicate the immune system is affecting insulin-producing cells) - Peopl...

Who might be able to join this trial: - People who are between 5 and 39 years old at the time of joining the trial - People who have not been diagnosed with diabetes according to the American Diabetes Association's diagnostic standards - People who have tested positive (on more than one occasion) for one or more specif...

Who might be able to join this trial: - Children and teenagers between 8 and 18 years old - Those who have been diagnosed with type 1 diabetes within the last 14 weeks - Those who are willing and able to have a non-invasive test to measure artery stiffness (lasting about 1 hour) and wear a blood pressure monitoring dev...

**Who might be able to join this trial:** - You are between 18 and 49 years old - You have been diagnosed with Type 1 diabetes, either confirmed by a blood antibody test or by a doctor's diagnosis along with needing insulin since you were diagnosed - You use an insulin pump or an automated insulin delivery system (some...

**Who might be able to join this trial:** - Non-smokers who are generally healthy, aged 18 to 55 (for Parts A–E) or 18 to 70 (for Parts F and G), of any gender - People with a body weight in a certain range relative to their height — specifically a BMI of 19 to 35 (Parts A–E), or a BMI of 30 to 50 (Parts F and G) - Pe...

**Who might be able to join this trial:** - People who are between 18 and 40 years old - People who have been diagnosed with Type 1 Diabetes for at least 1 year - People who have at least one area of their sleep health that is considered outside the normal range (confirm with trial site for details on how this is measu...

**Who might be able to join this trial:** - You are 18 years of age or older (or 19 or older, depending on where the trial is being run). - Your heart, liver, kidneys, and other organs are functioning well enough to meet the trial's requirements (confirm with trial site). - Your cancer can be measured on scans, accordi...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes for at least 1 year, based on symptoms or positive blood tests, and who are currently using insulin injections or a standard (non-automated) insulin pump - People whose HbA1c (a measure of average blood sugar over roughly 3...

**Who might be able to join this trial:** - The child must be between 5 and 12 years old. - The child must have been diagnosed with diabetes within the last 3 months. - If the child has had diabetes for 2 months or more at the time of joining, their blood sugar control level (called HbA1c, adjusted for insulin use) mus...

Who might be able to join this trial: - You are able to have a blood sample taken Who may not be able to join: - There are no listed exclusion criteria at this time (confirm with trial site) Important: Always verify eligibility with the trial site directly before applying.

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes - People who have had diabetes for at least 6 months - People who regularly attend their clinic appointments - People who have started using the MiniMed 780G automated insulin delivery system Who may not be able to join: - Chil...

Who might be able to join this trial: - Children between 8 and 13 years old - Children who were diagnosed with Type 1 Diabetes at least 6 months ago - Children who are able to read and write in Turkish - Children who are able to communicate verbally - Children who have access to the internet at home - Children who have...

Who might be able to join this trial: - You have been diagnosed with Type 1 Diabetes Who may not be able to join: - You are currently pregnant or breastfeeding - You have other ongoing (long-term) or current (short-term) illnesses or health conditions - You have taken antibiotics at any point in the last 3 months Imp...

**Who might be able to join this trial:** - You have agreed to take part and signed a dated consent form - You are 18 years old or older and have received a kidney transplant - It has been more than 3 months since your kidney transplant - Your kidneys are still working at a reasonable level, based on a blood test calle...

**Who might be able to join this trial:** - Men and women of any race or ethnicity - People who are not obese (body mass index of 30 or below) - People who have been diagnosed with type 1 diabetes - People whose body is no longer producing insulin on its own (confirmed by a "C-peptide negative" test result — confirm wi...

**Who might be able to join this trial:** This trial has three separate subgroups. People may be considered for one of the following: **Subgroup 1:** - Adults aged 18 or older - A blood sugar control measure (HbA1c) below 6.5%, meaning blood sugar levels are in or near the normal range - Willingness to provide writte...

**Who might be able to join this trial:** **For young people (ages 10–13) and their parent or guardian:** - The young person has been diagnosed with type 1 diabetes (according to standard medical guidelines) for at least 6 months - The young person is between 10 and 13 years old at the time of signing consent - The y...

**Who might be able to join this trial:** - People aged 18 or older. - People who have been clinically diagnosed with type 1 diabetes for at least one year, based on the treating doctor's judgment (no specific blood tests to confirm the diagnosis are required for this purpose). - People who have been using a commercial...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have Type 1 diabetes - People who have been using a closed-loop system or insulin pump for at least 6 months - People who are experiencing moderate or high levels of diabetes-related emotional distress, based on a specific questionnaire sc...

Who might be able to join this trial: - You must be willing and able to sign a consent form agreeing to take part in the study. - You must be male or female, aged 40 or older, and have had Type 1 diabetes for more than 10 years (diagnosed before age 30 with insulin used from the start, or if diagnosed after 30, insulin...

**Who might be able to join this trial:** - People who have been diagnosed with Type 2 Diabetes - People between 18 and 75 years of age - People who have never used insulin, and who have been taking a stable dose of 2 or more blood sugar-lowering medications (such as metformin, sulphonylurea, SGLT-2 inhibitors, GLP-1...

**Who might be able to join this trial:** - The baby (after birth) has a close family member (mother, biological father, or full brother/sister) who has type 1 diabetes - The mother is 18 years old or older - The mother is both the birth mother and the biological mother of the baby - The mother is no more than 24 weeks...

**Who might be able to join this trial:** - People who have type 1 diabetes (based on self-reporting) - People who have recently been prescribed the Omnipod 5 System and have been using it for no more than two weeks, or who plan to start using it within the next two weeks - People who are willing to use only one of th...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with Type 1 diabetes or a slow-developing form of adult autoimmune diabetes (called LADA) for at least one year - Your recent average blood sugar level (HbA1c) is above 8.0%, and your blood sugar levels vary a lot throughout...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes for at least 6 months - People who are close to their last appointment with a pediatric (children's) type 1 diabetes healthcare provider, with that final visit expected to happen within about one month of joining the study - Peo...

**Who might be able to join this trial:** - You are between 6 and 65 years old (any gender). - You have been diagnosed with type 1 diabetes for at least 1 year, confirmed by at least one positive result for a diabetes-related antibody test. - Your blood sugar is not well controlled despite using intensive insulin ther...

**Who might be able to join this trial:** - People who have had Type 1 diabetes for at least 8 years and were started on insulin within one year of being diagnosed. - People whose kidneys are working at a reduced but specific level — measured by a blood test called eGFR, with a result between 20 and 60 on a standard s...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes for at least 12 months and have been using multiple daily insulin injections for at least 6 months - People whose blood sugar control measure (called HbA1c) is 7.0% or above at the screening visit — there is no upper limit o...

Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the study - People who have been diagnosed with type 1 diabetes for at least 5 years, were diagnosed before the age of 18, and have had at least one blood sugar control reading (HbA1c) of 70 mmol/mol or higher recorde...

**Who might be able to join this trial:** - People who are male, or female and neither pregnant nor breastfeeding at the time of giving consent - People who have a confirmed diagnosis of type 1 diabetes, based on their previous medical records - People (or their legal representative) who are willing to give informed co...

Who might be able to join this trial: - People who are willing and able to give informed consent to participate. - People who have a solid tumour cancer that has been confirmed by lab testing (tissue or cell sample) and is either locally advanced or has spread to other parts of the body, and who are not eligible for st...

**Who might be able to join this trial:** - You have been officially diagnosed with type 1 or type 2 diabetes for at least 1 year - You are between 18 and 65 years old (inclusive) - You are currently managing your diabetes using insulin injections, insulin pumps, a hybrid closed-loop system (an automated insulin delive...

Who might be able to join this trial: - People who agree to take part and sign a consent form - People who have been diagnosed with type 1 diabetes (based on 2024 American Diabetes Association criteria) - People aged between 18 and 70 years old - People who depend on insulin injections and whose insulin treatment plan...

Who might be able to join this trial: - You are between 10 years and 0 months old and 14 years and 11 months old - You have been diagnosed with Type 1 diabetes - You have had Type 1 diabetes for at least 6 months - You identify as Black - Your primary caregiver (such as a parent or guardian) is willing to take part in...

Who might be able to join this trial: **For healthy volunteers (Part A):** - People who are in generally good health, based on their medical history and a physical check-up. **For people with Type 1 Diabetes (Parts B and C):** - People who have had Type 1 Diabetes for at least 2 years, with low levels of a protein ca...

**Who might be able to join this trial:** - People who are female - People who are between 18 and 40 years old at the time of joining - People who had their first period at least one year before joining the trial - People who have had at least one menstrual period in the last 40 days - People whose menstrual cycles are...

**Who might be able to join this trial:** - Children and teenagers aged between 2 and 17 years and 11 months old - People who have been diagnosed with type 1 diabetes for at least 3 months but no more than 6 months, based on World Health Organization standards - People who have tested positive for at least one of the...

**Who might be able to join this trial:** *For children with Type 1 Diabetes:* - Girls who are 10–11 years old, or boys who are 11–12 years old - Has been diagnosed with Type 1 diabetes for at least 6 months - The child and their parent or guardian are able and willing to give their agreement to take part *For typica...

Who might be able to join this trial: - You have been diagnosed with type 1 diabetes. - You are 18 years old or older. - You are willing and able to sign a consent form agreeing to take part in the trial. Who may not be able to join: - You are under 18 years old. - You are currently pregnant. - You have type 2 diabete...

**Who might be able to join this trial:** - People who want to increase the amount of physical activity they do each day - People who currently use a continuous glucose monitor (a small device that tracks blood sugar levels throughout the day) **Who may not be able to join:** - People who were diagnosed with type 1 di...

Who might be able to join this trial: - You are a woman between the ages of 18 and 45 who has been living with type 1 diabetes for at least 12 months - You have not yet gone through menopause, and you either have regular menstrual periods or are currently taking the contraceptive pill Who may not be able to join: - Yo...

**Who might be able to join this trial:** - Adults between 18 and 65 years old. - People who have had Type 1 diabetes for at least 5 years, with the condition first diagnosed before age 40. - People who are able to understand and agree to take part in the study. - People who are able to follow all study requirements,...

Who might be able to join this trial: - You have been diagnosed with Type 1 Diabetes (T1D) - Your HbA1c (a measure of average blood sugar over the past few months) is 8% or below - You currently use an insulin pump to manage your diabetes - You are an adult between 18 and 45 years old, of any gender - Your Body Mass In...

Who might be able to join this trial: - You have been diagnosed with Type 1 or Type 2 Diabetes - You are currently admitted as an inpatient at Stanford Healthcare - You live in California at the time of joining the trial - You have been identified as having concerns about getting enough food (food insecurity) - Your he...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with Type 1 diabetes for at least 3 years - People who have had at least one low blood sugar episode in the past 2 months — either a moderate low (blood sugar below 54 mg/dL or 3 mmol/L, confirmed by a monitor) or a se...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes according to American Diabetes Association criteria - People (both women and men) who are currently using the Medtronic MiniMed 780G advanced closed loop insulin system - Women who have had regular menstrual cycles lasting betwe...

**Who might be able to join this trial:** This trial has two separate parts with different eligibility requirements: **Part 1 (Aims 1–3): For people with early-stage type 1 diabetes (Stage 2)** - You are between 12 and 50 years old - Your body weight falls within a healthy range for your age (BMI 18–31 for adults, or...

**Who might be able to join this trial:** - People who are between 18 and 45 years old - People who are able to understand and agree to participate in the study (give informed consent) - People who are pregnant with one baby (not twins or more) - People who are planning to give birth at Turku University Hospital - Peop...

Who might be able to join this trial: - People who are willing to take part in the study voluntarily - People whose parents or guardians have given their approval for participation - Children who are between 7 and 12 years old - Children who have recently been diagnosed with Type 1 Diabetes for the first time - Childre...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes for at least 12 months - People who use a continuous glucose monitor (a small device that tracks blood sugar levels throughout the day) as part of managing their diabetes - People whose continuous glucose monitor is worn 70%...

**Who might be able to join this trial:** - People who are at least 18 years old - People who have been diagnosed with Type 1 diabetes for at least one year, as confirmed by their diabetes doctor and the trial's lead investigator - People who have been using a commercial advanced automated insulin delivery system (a ty...

**Who might be able to join this trial:** - Adults aged 30 years or older - People who have been diagnosed with Type 1 diabetes, or a condition called latent autoimmune diabetes in adults (LADA) that is being treated as Type 1 diabetes - People whose diabetes distress score is 2.0 or higher on a specific scale called t...

Who might be able to join this trial: - Children and teenagers between 8 and 18 years old, which is the age range approved for the continuous glucose monitoring (CGM) devices used in this trial - People who have had Type 1 diabetes for at least 6 months - People who can speak, read, and write in English or Spanish - Pe...

**Who might be able to join this trial:** - People aged 18 to 30 years old who have been diagnosed with Type 1 diabetes (T1D). - People whose diabetes was diagnosed at least 12 months ago. - People whose body mass index (BMI) is 30 or higher, or whose BMI is 27 or higher along with a health condition related to their...

**Who might be able to join this trial:** *For the newly diagnosed Type 1 diabetes group:* - Children aged 2 years or older but under 18 years old at the time of joining - Children weighing at least 12 kg - Children who have been recently diagnosed with Type 1 diabetes, confirmed using recognised international criteri...

**Who might be able to join this trial:** - You are between 18 and 84 years old. - You have Type 1 diabetes. - Your daily insulin dose is at least 0.5 units per kilogram of your body weight, or your BMI is 25 or higher. - You are already using a continuous glucose monitor (a device that tracks your blood sugar through...

Who might be able to join this trial: - People who have been diagnosed with Type 1 Diabetes - People who are 18 years of age or older - People who have given written consent to take part in the trial Who may not be able to join: - People who drink excessive amounts of alcohol - People who have other known causes of li...

Who might be able to join this trial: - Babies who are between 3 and 4 months old at the time of joining the trial - Babies who have a high genetic risk (greater than 10%) of developing signs of type 1 diabetes by age 6, based on specific gene markers, a genetic risk score, and whether a close family member (parent or...

Who might be able to join this trial: - People who have Type 1 Diabetes - People whose most recent A1c blood sugar level is above 8.5% - People who do not currently use an insulin pump - People whose primary language is English or Spanish - People who have medical insurance coverage Who may not be able to join: - Peop...

**Who might be able to join this trial:** - People aged 6 to 35 years old - People who have been diagnosed with Type 1 diabetes (T1D) for fewer than 100 days at the time of joining the trial - People who are willing to give their own consent, or, if under 18 years old, have a parent or legal guardian who is willing to...

**Who might be able to join this trial:** **Adults (age 18 and over):** - People who are 18 years of age or older - People who have had Type 1 diabetes for at least 3 years - People who have been using a continuous glucose monitor (a small sensor that tracks blood sugar levels) for at least 6 months - People whose doc...

Who might be able to join this trial: - You have a Body Mass Index (BMI) of less than 30, meaning you are not classified as obese (you can check your BMI using an online calculator with your height and weight) Who may not be able to join: - Women who are currently pregnant or breastfeeding - People who currently smoke...

Who might be able to join this trial: - People with a clinical diagnosis of Type 1 diabetes that started before age 35, who needed insulin treatment within 1 year of being diagnosed — or, if diagnosed after age 35, who have had a positive autoantibody blood test linked to Type 1 diabetes (past or present) - People whos...

**Who might be able to join this trial:** - You are between 18 and 65 years old - You have been diagnosed with Type 1 diabetes for more than 1 year before joining the study - Your HbA1c (a measure of average blood sugar over roughly 3 months) is between 7.0% and 9.0% - Your method of taking insulin has not changed in...

**Who might be able to join this trial:** - Young people aged 11 to 17 years old at the time of joining the trial - People who have been diagnosed with type 1 diabetes for at least 12 months - People who are not getting enough sleep (less than 8 hours per night for 13–17 year-olds, or less than 9 hours per night for 1...

**Who might be able to join this trial:** - You are a woman aged 18–50 years old, or a man aged 21–50 years old - You have been diagnosed with type 1 diabetes based on standard medical criteria, such as specific blood sugar or HbA1c test results - You have a documented history of at least one diabetes-related antibody...

**Who might be able to join this trial:** - People aged 16 years or older who can speak and read Arabic - People who have been diagnosed with Type 1 diabetes for at least 6 months - People whose blood sugar is not well controlled, meaning their HbA1c blood test result is 7% or higher, and/or their fasting blood sugar...

**Who might be able to join this trial:** - People who have never used a GLP-1 receptor agonist medication (a type of diabetes/weight loss drug), or whose last dose of one was at least 6 months before the screening visit. - For Parts A and B (single-dose and food/medication effect testing): People who are generally he...

Who might be able to join this trial: - People who were diagnosed with Type 1 diabetes (T1D) as an adult (aged 18 or older) between 2001 and 2020, and are listed on the National Diabetes Register - People who were diagnosed with Type 2 diabetes (T2D) at age 18 or older between 2001 and 2020, and are recorded in the Nat...

**Who might be able to join this trial:** - Adults aged 18 or older. - People who have been diagnosed with biliary tract cancer (a cancer affecting the bile ducts or gallbladder), confirmed through a laboratory test of cancer tissue, and who have previously been treated with a specific combination of chemotherapy and...

**Who might be able to join this trial:** - Both the child or teenager and their parents must be willing to sign a consent form agreeing to take part - The young person must be between 7 and 17 years old (inclusive) when signing the consent form - The young person must have been diagnosed with type 1 diabetes for at le...

**Who might be able to join this trial:** - People aged 35 to 65 years old at the time of signing the consent form - People who have been officially diagnosed with type 1 diabetes for at least 5 years, diagnosed according to American Diabetes Association standards - People whose type 1 diabetes is unstable and not wel...

Who might be able to join this trial: - People who have been clinically diagnosed with Type 1 Diabetes for at least 1 year. - People who are already using a commercial hybrid closed-loop insulin system (a device that automatically adjusts insulin delivery). - People who are willing not to start any new non-insulin bloo...

Who might be able to join this trial: - People between 2 and 26 years of age at the time of joining the trial. - People who have been diagnosed with type 1 diabetes, are on insulin therapy, and need close blood sugar monitoring during a hospital stay and around the time of a surgical procedure. - People who are already...

Who might be able to join this trial: **General requirements (all participants):** - Adults between 18 and 60 years old - Body mass index (a measure of weight relative to height) between 18 and 28 - Weight of at least 50 kg **For people with Type 1 Diabetes (T1DM):** - Has had Type 1 diabetes for between 1 and 30 yea...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes for at least 1 year - People who have scored highly on a measure of depression or anxiety Who may not be able to join: - People with cognitive or developmental delays that would make it difficult to take part in the study activ...

**Who might be able to join this trial:** - You are 18 years of age or older. - You have been diagnosed with type 1 or type 2 diabetes. - Your wound (ulcer) measures at least 1.0 cm² in size at the time of joining. - Your wound has been present for at least 4 weeks. - Your wound is on your foot, with most of it located...

**Who might be able to join this trial:** - Adults between 18 and 50 years old who have been clinically diagnosed with Type 1 Diabetes for at least one year - People whose sleep schedule varies by at least one hour on a regular basis each week - People who want to improve their sleep and own a smartphone (Android or iP...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes for at least 12 months. - People aged between 18 and 65 years old (inclusive). - People who have been using an automated insulin delivery (AID) system for at least 3 months. - People whose HbA1c (a measure of average blood...

Who might be able to join this trial: - People who have been clinically diagnosed with type 1 diabetes for more than 1 year before signing the consent form (the diagnosis is based on the doctor's judgment; special blood tests are not required). - People whose HbA1c (a measure of average blood sugar over time) is below...

Who might be able to join this trial: - You are currently pregnant - You were diagnosed with type 1 diabetes before becoming pregnant - You are already using an automated insulin delivery system (a device that automatically adjusts your insulin based on your blood sugar levels) Who may not be able to join: - You have...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with type 1 or type 2 diabetes - People whose study eye has diabetic swelling at the centre of the retina, confirmed by a specific scan measurement of 320 μm or more on a Spectralis device - People whose vision in the study eye fall...

Who might be able to join this trial: - You are between 2 and 45 years old - You have a close family member (parent, sibling, or child) who has been diagnosed with Type 1 Diabetes - You are willing and able to sign a consent form (or have a parent/guardian sign on your behalf if you are a child) Who may not be able to...

**Who might be able to join this trial:** - The baby must be between 13 and 17 weeks old at the time of joining the trial. - The baby must have a higher-than-average genetic chance (7–10%) of developing signs of type 1 diabetes by age 6, based on specific gene patterns identified through genetic testing. - Babies with...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes for at least 1 year. - Adults aged 18 or older (any gender). - People whose average blood sugar level (measured by HbA1c or a sensor-based estimate called GMI) is 7.0% or higher at the screening appointment. - People who are phy...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been diagnosed with Type 1 diabetes for at least one year - People currently managing their diabetes using multiple daily insulin injections, an insulin pump, or an automated insulin delivery system - People whose HbA1c (a measu...

**Who might be able to join this trial:** - You are between 18 and 24 years old - You have been diagnosed with Type 1 diabetes for at least two years - Your recent blood sugar control level (measured over the past 30 days using a continuous glucose monitor) is below 9.9% - You already use a Dexcom G7 continuous glucose...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes - Children and teenagers between 6 and 18 years old - People who are currently using insulin (either through multiple daily injections or an insulin pump) and are planning to start using an automated insulin delivery (AID) syste...

**Who might be able to join this trial:** - Children aged 6 to 16 years old. - Children whose body weight and height fall within a healthy middle range for their age (between the 25th and 75th percentile on a standard growth chart), and who weigh at least 20 kg. - Children whose fasting blood sugar and sugar tolerance...

**Who might be able to join this trial:** - You are an adult (age 18–65) who has been diagnosed with Type 1 diabetes - You use insulin injections or an insulin pump to manage your diabetes - You currently use a continuous glucose monitor (CGM) - **If you have kidney disease:** You have been told your kidneys are worki...

Who might be able to join this trial: - People who are able and willing to give their informed consent to participate - People with a Body Mass Index (BMI) of 28 or higher (a measure of body weight relative to height) - People of African American ancestry - People who have been diagnosed with diabetic ketoacidosis (DKA...

**Who might be able to join this trial:** - People with obesity, meaning a Body Mass Index (BMI) between 30 and 50 kg/m², as measured at the screening appointment. - People who have tried at least once to lose weight through lifestyle changes (such as diet and exercise) without success. - People who have had Type 2 di...

**Who might be able to join this trial:** - You are between 18 and 70 years old (inclusive) - It has been more than one year since your spinal cord injury - Your spinal cord injury is at a level between C2 and L2, with any level of impairment on the standard injury scale (A, B, C, or D) - You are willing and able to s...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes for at least 1 year. - People who use daily long-acting and short-acting insulin injections or doses to manage their diabetes. - People who are fluent in English. - Families where a parent or caregiver is able to give consent an...

Who might be able to join this trial: - You were 14 years old or younger when you were diagnosed with type 1 diabetes - Your type 1 diabetes was diagnosed between January 2014 and December 2018 at the Pediatrics Unit of the IRCCS Azienda Ospedaliero-Universitaria hospital in Bologna, Italy - You have been monitored and...

**Who might be able to join this trial:** - Adults aged 18 or over - People who have type 1 diabetes, type 2 diabetes, or diabetes caused by a pancreatic disease - People who have been using multiple daily insulin injections (a background insulin plus mealtime insulin) for at least 6 months - People whose rapid-acting...

**Who might be able to join this trial:** - People who have been clinically diagnosed with type 1 diabetes for 5 or more years. - People who use an insulin pump (either a standard manual pump or a hybrid closed-loop/automated system) and have not changed their treatment method in the past 2 or more months, and are wil...

**Who might be able to join this trial:** - Adults aged 18 or older. - People who have been diagnosed with Type 1 diabetes for at least one year, as confirmed by their treating doctor. - People whose HbA1c blood sugar level has been below 11% at some point in the last six months. - People who are currently using intens...

**Who might be able to join this trial:** - You have been diagnosed with type 1 diabetes for more than 1 year. - You are between 18 and 65 years old. - Your body mass index (a measure of body weight relative to height) is 27 or above. - Your long-term blood sugar level (measured by an HbA1c test) is between 7.5% and 10...

Who might be able to join this trial: This trial has several different groups (called "work packages" or WPs). The criteria differ depending on which group a person may be considered for. **Group 1 (WP1) – Newly diagnosed type 1 diabetes, ages 2–30:** - People newly diagnosed with type 1 diabetes according to establi...

Who might be able to join this trial: - People aged 18 years or older - People with any type of diabetes that has been diagnosed for at least 1 year, who manage it using multiple daily insulin injections or an insulin pump - People who are currently wearing a continuous glucose monitor (a device that tracks blood sugar...

**Who might be able to join this trial:** - People who are willing and able to sign an approved consent form agreeing to take part in the study - Men and women (who are not pregnant or breastfeeding) between the ages of 12 and 35 years old - People who have been diagnosed with Stage 3 Type 1 Diabetes within the last 1...

Who might be able to join this trial: - People who are a parent or caregiver of a child diagnosed with Type 1 Diabetes (T1D) within the last 2 years - People who are 18 years of age or older - People who live in Canada - People who are willing to complete a 20-minute survey - People who can read and understand French o...

Who might be able to join this trial: - People between 18 and 29 years old - People who currently live in Ontario - People who have been diagnosed with Type 1 Diabetes (T1D) for at least 1 year, based on their own reported diagnosis - People who live independently in the community, not in a care facility or institution...

Who might be able to join this trial: - People who have given signed consent before any study-related activities begin. - People for whom the treating doctor and the patient (or their legal representative) have already decided — independently from this study — to start treatment with the commercially available medicati...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People who have been diagnosed with Type 1 or Type 2 diabetes - People who have a diabetic foot ulcer that is Grade 2, not infected, located below the ankle (but not between the toes), and has been present for at least 30 days - Peopl...

**Who might be able to join this trial:** - Parents of children diagnosed with Type 1 diabetes who are members of specific online communities, including the Mersin Diabetics WhatsApp group, the Type 1 Diabetics association on Instagram, or community forums and groups run by diabetes education nurses and dietitians — du...

**Who might be able to join this trial:** - People who have a clinical history of Type 1 Diabetes (a condition where the body cannot produce insulin) and have needed insulin for at least 5 years - People who have been on a stable anti-rejection medication routine — specifically tacrolimus combined with either mycopheno...

**Who might be able to join this trial:** **Part A (first phase of the trial):** - People with a body mass index (BMI) between 27 and just under 40 **Part B (second phase of the trial):** - Adults who have been diagnosed with Type 2 diabetes - People whose HbA1c blood sugar level (a measure of average blood sugar ove...

**Who might be able to join this trial:** - Adults aged 18 or older who are not pregnant and are currently admitted to Vanderbilt University Medical Center (VUMC) - People who are able to give their own informed consent to participate - People who have high blood sugar that requires insulin treatment (either injections...

Who might be able to join this trial: - Adults aged 18 to 55 years (male or female) who have been diagnosed with type 1 diabetes meeting standard diagnosis guidelines, which include a fasting blood sugar level of 126 mg/dL or higher, or a blood sugar level of 200 mg/dL or higher during a glucose tolerance test, or a Hb...

**Who might be able to join this trial:** - Your child is between 2 and 6 years old (inclusive) - Your child has been diagnosed with type 1 diabetes and is currently on insulin therapy - Your child is covered by social security (French national health insurance) - Your child is just starting treatment with a semi-close...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes according to recognised international guidelines for children and adolescents - People who have had diabetes for more than 12 months - People who are under 20 years old - People who have fully completed puberty, as assessed...

**Who might be able to join this trial:** - You are able to give your own consent to take part in the study - You are between 18 and 65 years old - You have been diagnosed with Type 1 diabetes - You have been using a Tandem t:slim X2 or Tandem Mobi insulin pump with the Control-IQ feature for at least 90 days before th...

Who might be able to join this trial: - You are currently pregnant and at least 34 weeks along - You have been diagnosed with type 1 diabetes for at least 1 year - You have been using a commercially available automated insulin delivery (AID) system since at least 28 weeks of your pregnancy - You are carrying one baby (...

**Who might be able to join this trial:** - You are 18 years old or older (any gender) - You have been diagnosed with Type 1 diabetes for at least one year - You have been using an automated insulin delivery (AID) system — sometimes called a "closed-loop" or "artificial pancreas" system — for at least three months - Yo...

Who might be able to join this trial: - People between one month and 18 years of age. - Both males and females are eligible. - People who have been diagnosed with type 1 diabetes. Who may not be able to join: - People younger than one month or older than 18 years of age. - People with a history of bleeding disorders o...

**Who might be able to join this trial:** - People aged between 50 and 80 years, of any sex - People who have had a diagnosis of Type 1 diabetes for at least 10 years, whether they manage it using multiple daily insulin injections or an insulin pump - People who are willing and able to give informed consent before any...

**Who might be able to join this trial (Screening Program):** - You are an adult who has been diagnosed with type 2 diabetes - You have seen a primary care doctor or provider at least once in the past 24 months - You have not had certain kidney function tests (specifically eGFR and/or urine albumin-creatinine ratio) re...

Who might be able to join this trial: - People aged between 18 and 50 years old - People who have Type 1 Diabetes, use an insulin pump, and wear a continuous glucose monitoring (CGM) device - People whose average glucose level (measured by a score called GMI) falls between 5.5% and 8.5%, with a normal blood count at th...

**Who might be able to join this trial:** - People who have been clinically diagnosed with type 1 diabetes (based on international standards and the doctor's judgment — blood tests for C-peptide or antibodies are not required) - Children and teenagers between the ages of 7 and 17 - People who can read and write in Gree...

**Who might be able to join this trial:** - People aged 18 to 55 years who have been diagnosed with Type 1 diabetes within the last 180 days (about 6 months) before the screening visit. - People whose pancreas is still producing some insulin, shown by a specific blood test result (called a C-peptide level) at or above...

**Who might be able to join this trial:** - Adults between 18 and 75 years old at the time of screening. - People with a body mass index (a measure of weight relative to height) within specific ranges depending on which part of the trial they join — generally between 27.0 and 45.0 (confirm with trial site for the spec...

Who might be able to join this trial: - You are 2 years old or older - You have been diagnosed with Type 1 diabetes for at least 6 months, recorded in your medical records - You identify as non-Hispanic Black or Hispanic - You receive your diabetes care at one of the six participating clinics, or at a matched partner c...

Who might be able to join this trial: - People who have had Type 1 diabetes for at least 6 months - People aged between 18 and 35 years old - People who score 2 or above on a diabetes-related distress questionnaire called the T1-DDS (either the overall score or a sub-section score) (confirm with trial site) - People wh...

**Who might be able to join this trial:** **Healthy participants (Part A):** - People who are in good general health, confirmed through a medical check-up including health history, physical examination, blood tests, and a heart screening **People with Type 2 diabetes (Part A):** - People who were diagnosed with Type...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 diabetes **Who may not be able to join:** - People who have other autoimmune diseases (conditions where the immune system attacks the body) - People who have diabetes-related blood vessel or nerve complications, whether affecting sm...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been clinically diagnosed with presumed Type 1 diabetes for at least 6 months - People who are less than 15 weeks pregnant at the time of joining the study, based on their due date from their healthcare provider - People w...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 or Type 2 diabetes for at least 6 months - People aged between 6 and 75 years old - People whose HbA1c blood sugar level result is 11% or below (confirm with trial site if unsure what your result means) - For Segment 1: People curre...

Who might be able to join this trial: - People who have type 1 or type 2 diabetes and are currently being treated with insulin Who may not be able to join: - People who are younger than 25 or older than 70 years of age - People whose HbA1c blood sugar level is above 10.0% (this is a measure of average blood sugar over...

Who might be able to join this trial: - You are 18 years of age or older - If you cannot become pregnant, you must be at least 1 year past menopause or have had a surgical procedure that prevents pregnancy; if you can become pregnant, you must agree to use two forms of contraception for the entire study - If you are ab...

Who might be able to join this trial: - Adolescents of Arab background - Males and females between 11 and 14 years of age - People who have been diagnosed with type 1 diabetes for at least 6 months - People who are currently wearing a continuous glucose monitor (a small device that tracks blood sugar levels) - People w...

Who might be able to join this trial: - Children who are older than 1 year and younger than 18 years old - Children with a Body Mass Index (a measure of body weight relative to height) below 30.0 kg/m² - Children who have been diagnosed with stage 3 type 1 diabetes, confirmed through clinical assessment, blood tests, h...

**Who might be able to join this trial:** **Phase 1 (up to 50 people):** - People aged 18–45 with type 1 diabetes who have severe complications, including advanced eye disease (proliferative retinopathy), large amounts of protein in the urine (macroalbuminuria), moderate-to-severe kidney disease (CKD class 3B or worse...

**Study 1** Who might be able to join this trial: - People who are male and in good general health (no existing medical conditions) - People aged between 18 and 50 years - People with a Body Mass Index (BMI) between 18 and 29 (a measure of body weight relative to height) Who may not be able to join: - People who have...

**Who might be able to join this trial:** - People who have Type 1 diabetes and whose blood sugar levels vary significantly and unpredictably, measured by specific medical tests showing high variability (confirm with trial site for exact measurements) - People whose blood sugar variability has continued for more than...

**Who might be able to join this trial:** - People who are older than 18 and younger than 89 years of age at the time of signing consent - People who have been clinically diagnosed with type 1 diabetes for at least one year and have been using insulin for at least one year - People who have been clinically diagnosed w...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes by a referring doctor - People whose diagnosis was received at least three months ago - People aged 18 years or older - People who have access to a computer or smartphone that can be used for video calls - People who have not ex...

**Who might be able to join this trial:** - You have been diagnosed with at least one of the following: high blood pressure, type 2 diabetes, high cholesterol, chronic kidney disease, and/or metabolic syndrome. - You are 18 years of age or older at the time of signing the consent form. - You have reliable transportati...

**Who might be able to join this trial:** - Children and teenagers between 1.5 years and 18 years of age - People who have a close family member (parent, sibling, or child) who has been diagnosed with Type 1 Diabetes - Cases where a parent or legal guardian is able to sign the consent forms on the child's behalf **Who...

**Who might be able to join this trial:** - People who are 18 years old or older at the time of signing consent - People who have been clinically diagnosed with Type 1 Diabetes for at least one year, based on a doctor's assessment - People who have used an FDA-approved automated insulin delivery (AID) system at some p...

**Who might be able to join this trial:** - The participant is between 12 years old and 17 years and 5 months old at the time of joining the trial - Body weight falls within the required range — 34 to 80 kg for males, and 37 to 80 kg for females - A diagnosis of type 1 diabetes has been made according to the criteria o...

**Who might be able to join this trial:** - People with type 1 diabetes who have been using a Dexcom or Abbott Libre glucose sensor (any model) for at least 14 days before the pump is set up, with the sensor recording data at least 70% of the time during that period - People for whom a diabetes specialist has decided...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes by their own doctor or specialist. - People whose blood sugar levels have been in the healthy target range less than 80% of the time over the four weeks before the screening visit. Who may not be able to join: - People who have...

Who might be able to join this trial: - People who are 18 years old or older - People who were diagnosed with Type 1 or Type 2 diabetes by a clinician within the NHS more than one year ago - People who are managing their own diabetes condition - People whose NHS care team has identified them as needing support with the...

Who might be able to join this trial: - People who have Type 1 Diabetes - People who speak Spanish or English fluently and live in the greater New Haven area Who may not be able to join: - People who have a cognitive impairment or are otherwise unable to give written consent to participate in the study Important: Alw...

**Who might be able to join this trial:** - People who have been diagnosed with Stage 3 Type 1 diabetes recently, following standard diagnostic guidelines, and who can be enrolled within 6 months of their diagnosis and within 37 days of their screening visit. - People who have at least one positive diabetes-related au...

Who might be able to join this trial: - You have recently been diagnosed with type 1 diabetes within the last 100 days. - You are between 18 and 45 years old. - Your Body Mass Index (BMI) is between 18 and 30 (a measure of weight relative to height). - Your body is still producing some of its own insulin, shown by a de...

Who might be able to join this trial: - Adults (male or female) who have given written consent before any trial-related activities begin. - People who have had a confirmed diagnosis of Type 1 diabetes (as defined by the American Diabetes Association 2024 criteria) for at least 1 year before the screening visit, with a...

**Who might be able to join this trial:** - People of any age who have been diagnosed with type 1 diabetes, no matter how long they have had it - People whose type 1 diabetes diagnosis was confirmed by a specialist doctor - People who meet at least one of these features of their diabetes: were diagnosed before age 15,...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 Diabetes - People aged 6 years or older, of any gender - People whose Type 1 Diabetes diagnosis was more than 3 months ago - People who are planning to attend follow-up appointments at the study hospital over the next year - People...

Who might be able to join this trial: - Adolescents aged 13–17 or young adults aged 18–21 years old - People who have been diagnosed with Type 1 diabetes for at least one year - People who have access to a smartphone - People who have an active My Health at Vanderbilt (MHAV) patient portal account - People who can read...

Who might be able to join this trial: - People aged between 6 months and 70 years old (male or female) - People who have tested positive for at least one specific antibody linked to type 1 diabetes (insulin, GAD, IA2, or ZnT8), with that result confirmed by a reference laboratory - People aged 16 or older who are willi...

Who might be able to join this trial: - People who have been diagnosed with Type 1 Diabetes for more than 5 years - People whose pancreas produces very little insulin on its own, shown by a specific blood test result (2-hour C-peptide level below 0.3 ng/mL) taken after consuming a mixed meal - People who are on continu...

**Who might be able to join this trial:** - People who are willing and able to give their agreement to take part, or for those under 18, a parent or legal guardian must give consent on their behalf. - People aged 8 to 45 years old at the time of signing the consent forms (note: the trial initially accepts only adults...

Who might be able to join this trial: - People who are over 18 years old - People who are a parent or legal guardian of a child diagnosed with type 1 diabetes (as defined by the American Diabetes Association) - People whose child received a type 1 diabetes diagnosis less than 1 week ago - People who live with the child...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with type 1 diabetes according to World Health Organization diagnostic criteria - People who are able and willing to take part in a 12-hour structured diabetes education course - People who are able and...

Who might be able to join this trial: - People who are 17 years old (for the intervention group) or between 17.5 and 18 years old (for the control group) - People who have been diagnosed with type 1 diabetes, asthma, and/or obesity - People who have had at least one outpatient appointment at one of the two participati...

**Who might be able to join this trial:** - People who have been diagnosed with type 1 diabetes mellitus - Children aged 6 to 18 years old (along with their caregivers), or adults over 18 years old - People whose HbA1c blood sugar level (a measure of average blood sugar over recent months) was between 7.2% and 10.5% in...

Who might be able to join this trial: - People who identify as non-Hispanic Black - People who have been diagnosed with type 1 diabetes and are currently being treated with insulin - People who are currently using, or have used in the last 3 months, an automated insulin delivery system (a device that combines a continu...

**Who might be able to join this trial:** - People who weigh at least 43 kg (about 95 pounds) - People who have at least one islet autoantibody (a marker in the blood that can indicate the immune system is affecting the pancreas), and/or have been diagnosed with clinical Type 1 diabetes within the last 100 days - There...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have been diagnosed with type 1 or type 2 diabetes. - People who have more than one foot ulcer, where the ulcer being treated in this trial is the same one that was treated in the previous CAMPX study. - People who are wil...

**Who might be able to join this trial:** - You are 18 years old or older - You came to an emergency department unexpectedly with very high blood sugar (above 250 mg/dL) and high levels of a substance called ketones in your blood, which together suggest a condition called diabetic ketoacidosis (DKA) - Your diabetes app...

Who might be able to join this trial: - You are between 7 and 18 years old - You have had Type 1 diabetes for more than 6 months - You are currently using the MiniMed 780G insulin pump system with the automatic mode turned on Who may not be able to join: - You have serious complications related to your diabetes - You...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have had a diagnosis of type 1 diabetes or autoimmune diabetes for at least 12 months - People with a body mass index (BMI) of 30 or higher (a measure of body weight relative to height) - People whose average blood sugar level (HbA1c) is...

**Who might be able to join this trial:** - People who are willing and able to sign a consent form agreeing to take part in the study - People who are able to attend and follow all study requirements for the full duration of the trial - People who have had type 1 diabetes for at least one year - People aged 18 to 45 y...

**Who might be able to join this trial:** **Adults with type 1 diabetes:** - Adults aged 18 years or older - People who were diagnosed with type 1 diabetes more than one year ago - People who have been using a Continuous Glucose Monitoring (CGM) device — a sensor that tracks blood sugar levels throughout the day — for...

Who might be able to join this trial: - Adults who are 18 years of age or older. - People who have been diagnosed with either type 1 or type 2 diabetes. - People who are able to communicate in Thai. - People who are willing and able to sign a written consent form agreeing to take part. Who may not be able to join: - P...

**Who might be able to join this trial:** - The patient and their parent or caregiver must have given written consent to participate - The child must have been diagnosed with Type 1 diabetes (as defined by the American Diabetes Association) within the 3 months before the screening visit - The child must have been betw...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes by a doctor, and whose doctor has set them up with a specific insulin pump (the t:slim X2 with Control-IQ technology) along with a Dexcom G6 or G7 continuous glucose monitor. - People aged 6 years or older at the time of joining...

Who might be able to join this trial: - Both the young person and their parent or guardian must agree to take part and give their consent. - The young person must be between 12 and 16 years old. Who may not be able to join: - People who do not have access to the internet or modern technology devices. - People who do n...

Who might be able to join this trial: - You are 19 years of age or older and are the parent or legal guardian of a child who has Type 1 Diabetes - You live in a rural area that is more than 1 hour away from the nearest pediatric diabetes specialist care team - You have access to a reliable internet connection at home...

Who might be able to join this trial: - Be between 10 and 17 years old - Have been diagnosed with stage 3 Type 1 Diabetes (T1D), meaning blood sugar levels are high enough to meet standard diabetes diagnosis guidelines - Be able to start the study treatment within 21 days of their diabetes diagnosis (counting from the...

**Who might be able to join this trial:** *(For people who are planning a pregnancy):* - Women between the ages of 18 and 45 - People who have been living with type 1 diabetes for at least 12 months - People who are not currently pregnant, confirmed by a negative pregnancy test on the day they are enrolled in the tria...

Who might be able to join this trial: - People who have had type 1 diabetes for at least 12 months - People aged between 18 and 64 years old - People whose HbA1c (a measure of average blood sugar levels over roughly 3 months) is 9.0% or below - People whose Body Mass Index (BMI) falls between 18.5 and 29.0 - People who...

**Who might be able to join this trial:** - People who have had Type 1 diabetes for more than five years (diagnosed using World Health Organization standards) and have a very low level of c-peptide (a marker of insulin production) below 200 pmol/L - People aged between 18 and 80 years old - People who already use a co...

Who might be able to join this trial: - People of any ethnicity are welcome to participate - You must be a seafarer who needs insulin to manage your blood sugar (diabetes) - You must hold a valid ML5 or ENG1 certificate (a type of medical fitness certificate for seafarers) - You must be willing and able to wear a Conti...

**Who might be able to join this trial:** - People who are willing and able to give written consent to take part - People aged between 18 and 65 years old - People who have been diagnosed with Type 1 Diabetes according to recognised 2024 medical guidelines - People whose blood tests show 2 or more specific markers (ca...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 Diabetes. - People who have had diabetes for more than 12 months at the time of screening. - Adults aged 18 years or older. - People whose HbA1c (a blood sugar level measured over roughly 3 months) is above 57 mmol/mol at screening....

Who might be able to join this trial: - People who have a history of stage 2 type 1 diabetes, confirmed in their medical records, including the presence of one or more diabetes-related antibodies and abnormal blood sugar levels - People who, at the time of joining, have not yet been diagnosed with full type 1 diabetes...

Who might be able to join this trial: - People aged 40 or older who have had Type 1 diabetes for more than 10 years, diagnosed before age 30 (or after 30 with specific supporting evidence such as a diabetic emergency at onset or positive antibody tests). - People who have at least one of the following: kidney disease (...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with type 1 or type 2 diabetes - People who are currently using a continuous glucose monitoring (CGM) system, which is a device that tracks blood sugar levels throughout the day - People who are being treated with ins...

Who might be able to join this trial: - People who are between 16 and 19 years of age - People who have had type 1 diabetes for at least 12 months - People who have recently had an HbA1c (a blood sugar level measurement) result of 7.0% or higher - People who currently receive diabetes care at a Seattle Children's Hospi...

Who might be able to join this trial: - You are pregnant - You are 18 years old or older - You have Type 1 diabetes - You are planning to give birth vaginally and have been admitted to the labor and delivery unit - You are carrying a single baby with no major birth defects - You are at least 35 weeks pregnant - Your ce...

Who might be able to join this trial: - Adults between 18 and 65 years of age (inclusive) - People with type 1 diabetes who have been using intensive insulin therapy — either multiple daily injections or an insulin pump (with or without a continuous glucose monitor that automatically adjusts insulin doses) — for at lea...

Who might be able to join this trial: - People who are scheduled to have weight-loss (bariatric) surgery Who may not be able to join: - People who have already had weight-loss (bariatric) surgery in the past Important: Always verify eligibility with the trial site directly before applying.

Who might be able to join this trial: - People whose HbA1c (a blood sugar level measured over time) is below 9% - People currently managing their diabetes using multiple daily injections, with both a long-acting and short-acting insulin (called MDI Bolus-Basal therapy) - People who wear a continuous glucose monitor (CG...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with chronic kidney disease (CKD) at stages G1, G2, G3a, G3b, or G4, and who are not currently being considered for dialysis treatment - People who have uncontrolled type 2 diabetes, cardiovascular disea...

Who might be able to join this trial: - People who have been diagnosed with Type 1 diabetes and are at least 2 years old - People who have been prescribed a specific insulin pump system called the Omnipod 5, used together with a FreeStyle Libre 2 Plus sensor, within the last year - People who have never used the Omnipo...

Who might be able to join this trial: - People living with Type 1 diabetes (T1D), or a rare form of diabetes that requires insulin, such as Latent Autoimmune Diabetes of Adults (LADA), Maturity-Onset Diabetes of the Young (MODY), or type 3c diabetes (which develops after an injury to or removal of the pancreas). - Peop...

Who might be able to join this trial: - People who were diagnosed with Type 1 diabetes more than 1 year ago (to ensure the early "honeymoon period" after diagnosis has passed) - People who manage their diabetes using multiple daily insulin injections, an insulin pump, or a hybrid closed-loop system - People using a hyb...

Who might be able to join this trial: - Adults aged 18 to 60 years old at the time of signing the consent form - People who have been diagnosed with Type 1 diabetes for at least 12 months - People who have been using an insulin pump or taking multiple daily insulin injections (both a long-acting and short-acting insuli...

Who might be able to join this trial: - People who are 12 years of age or older - People who are currently living in Canada - People who have been living with type 1 diabetes for more than 1 year - People who use at least 2 insulin injections per day, or who use an insulin pump - People who have been using their curren...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with a solid tumour (a type of cancer), confirmed through laboratory testing of a tissue sample - People who are currently receiving a type of cancer treatment called immune checkpoint inhibitor therapy — either...

Who might be able to join this trial: - People who are willing and able to give informed consent, or who have a parent or legally authorised representative who can do so on their behalf - People who are 6 years of age or older - People who have been diagnosed with Type 1 diabetes (T1D) - People who are currently using...

**Who might be able to join this trial:** - You must have received at least one teplizumab infusion in the 6 weeks before joining the study. - You must have been officially diagnosed with Stage 2 type 1 diabetes by your doctor at the time of your first teplizumab infusion (note: if your condition has since progressed t...

**Who might be able to join this trial:** - You are between 50 and 80 years old - You have been diagnosed with type 1 or type 2 diabetes (there are additional requirements depending on which type — see below) - If you have type 1 diabetes, you have had it for 10 years or more - If you have type 2 diabetes, you have had...

Who might be able to join this trial: - People who have been diagnosed with type 1 diabetes - People who are between 8 and 12 years old - People who have had type 1 diabetes for at least 1 year and have completed standard diabetes education - People who are able to read and write Who may not be able to join: - People...

**Who might be able to join this trial:** - People aged 18 or older - People who have had their lung cancer confirmed through a tissue or cell sample, and whose cancer type is non-small-cell lung cancer (NSCLC) - People who have not previously received any cancer treatment such as chemotherapy, immunotherapy, or radio...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been taking the medication sulfasalazine for at least 2 months before joining the trial - People who have been diagnosed with an inflammatory arthritis condition, such as Rheumatoid Arthritis, Reactive Arthritis, Axia...

Who might be able to join this trial: - Children and adolescents under 12 years of age - People who have been diagnosed with Type 1 Diabetes (a condition where the body does not produce insulin) - People whose Type 1 Diabetes diagnosis was made more than 1 year ago - People who manage their diabetes using multiple dail...

Who might be able to join this trial: - People who have already been diagnosed with, or are newly diagnosed with, type 1 diabetes or a related condition called LADA (a slowly developing form of diabetes in adults) - People aged 18 to 75 years old - People of any sex - People who are seen as outpatients at the Center of...

Who might be able to join this trial: - Children under 18 years old who have been diagnosed with type 1 diabetes and are being seen at the University Hospital of Saint-Etienne - Children under 18 years old without diabetes or nerve-related conditions who are being included as a comparison group, matched by age (within...

**Who might be able to join this trial:** This trial has three separate groups. A person may be considered for one of the following groups: **Group 1 – People with Type 1 Diabetes:** - People who have been diagnosed with Type 1 diabetes according to World Health Organization diagnostic guidelines - People who are abl...

Who might be able to join this trial: - People who are 18 years of age or older - People who have diabetes that requires insulin, including type 1 diabetes, diabetes caused by chronic pancreatitis, a genetic form of diabetes called MODY, or diabetes related to cystic fibrosis - People who have completed a full pancreat...

Who might be able to join this trial: - People who have been diagnosed with type 1 or type 2 diabetes and also have at least one other health condition, such as obesity, HIV, heart failure, polycystic ovary syndrome, obstructive sleep apnea, or prediabetes (with or without high blood pressure) - People who are able to...

Who might be able to join this trial: - Children between 2 and 16 years of age - Children who have recently been diagnosed with type 1 diabetes for the first time - Children who are being admitted to hospital for their initial diabetes assessment and treatment - Children may be included whether or not they had a seriou...

**Who might be able to join this trial:** - You must be 18 years old or older at the time you agree to join the study. - You must have been diagnosed with Type 1 diabetes for more than 1 year, based on a doctor's assessment. - You must have used an FDA-approved automated insulin delivery (AID) system at some point in...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been clinically diagnosed with diabetes mellitus for at least one year - People who are willing to sign a consent form and follow the study's requirements **Who may not be able to join:** - People who have had a sever...

Who might be able to join this trial: - People aged between 31 and 75 years old - People who have had Type 1 Diabetes for at least one year - People where one or more aspects of their sleep health have been measured as outside the normal range Who may not be able to join: - People whose primary language is not English...

**Who might be able to join this trial:** - You are between 18 and 40 years old (inclusive). - You have been diagnosed with stage 2 or stage 3 type 1 diabetes, based on the American Diabetes Association's 2024 guidelines. - At least one specific diabetes-related antibody was found in your blood at screening (such as GA...

Who might be able to join this trial: - Adults aged 19 to 65 years old at the time of screening who are generally healthy. - People whose body weight is between 50.0 kg and 100.0 kg, and whose Body Mass Index (BMI) is between 20.0 and 29.9 kg/m² at screening. - People who have no birth defects, no ongoing conditions re...

Who might be able to join this trial: - People who are willing to take part and are able to sign a consent form agreeing to participate - People aged between 18 and 65 years - People who have been diagnosed with type 1 diabetes according to American Diabetes Association 2024 guidelines - People who test positive for at...

**Who might be able to join this trial:** **For the control group (people without diabetes or cholesterol problems):** - You have given written agreement to take part in the study - Your fasting blood sugar level is below a certain threshold (confirm with trial site for exact value) - Your triglyceride (blood fat) lev...

Who might be able to join this trial: - Adults aged 18 or older - People who have been diagnosed with type 1 diabetes - People who have been using a closed-loop insulin delivery system (an automated system that monitors blood sugar and adjusts insulin automatically) for at least 4 months - People who are currently bein...

**Who might be able to join this trial:** - People who were diagnosed with Type 1 diabetes at least 1 year before joining the study - Children and teenagers between 9 and 18 years old - People who are currently attending school in Istanbul - People who are willing to take part in the study and have given their voluntar...

**Who might be able to join this trial:** - Adults aged 18 to 65 years old, of any race or gender - People with a body mass index (a measure of body weight relative to height) between 18 and 38 - Women who are not pregnant or breastfeeding, and all participants who agree to use contraception as specified by the trial...

Who might be able to join this trial: **All participants must meet these criteria:** - A signed consent form must be completed before any study-related activities begin - Participants must be male or female (based on sex at birth) and not able to become pregnant - Participants must be between 18 and 64 years old at th...

Who might be able to join this trial: - You are between 21 and 50 years old (male or female) - If you have Type 1 diabetes (T1D): you have had it for at least 5 years and your recent average blood sugar level (HbA1c) is 8.5% or below, managed with daily insulin injections or an insulin pump - Your body mass index (BMI...

Who might be able to join this trial: **Single Dose Group (SAD cohorts):** - Women who cannot become pregnant, or men, aged 18 to 55 years old at the time of screening - People with a body mass index (BMI) between 18.5 and 29.9 at screening (this is generally considered a "normal" to "overweight" range) - People who a...

**Who might be able to join this trial:** - People aged 14 to 75 years (inclusive) at the time of signing consent - People who have had a Type 1 diabetes diagnosis for at least 6 months, or a Type 2 diabetes diagnosis for at least 1 year, based on the doctor's judgment - People who are currently using basal/bolus insu...

**Who might be able to join this trial:** - You are male or female and are over 18 years old - You have been diagnosed with type 1 diabetes for more than 5 years, and certain diabetes-related proteins (autoantibodies) were found in your blood either at diagnosis or during a routine visit at Diabeter Centrum - Your panc...

**Who might be able to join this trial:** *For Parts A and B:* - People between 18 and 65 years of age - People who are generally in good health with no significant medical conditions *For Part C:* - People between 40 and 75 years of age - People who have been diagnosed with Type 2 diabetes **Who may not be able to...

Who might be able to join this trial: - Adults aged 18 years or older. - People who have been diagnosed with either type 1 or type 2 diabetes. - People who are currently receiving ongoing diabetes care through an outpatient clinic or primary healthcare setting (such as a GP). - People who are able to communicate verbal...

Who might be able to join this trial: - People aged 2 to 70 years old at the time of signing the consent form - People who have had a Type 1 diabetes diagnosis for at least 6 months (or at least 3 months for children aged 2 to 7 years), based on the study doctor's assessment - People who currently use a basal/bolus ins...

**Who might be able to join this trial:** - People who have been diagnosed with Type 1 or Type 2 diabetes for at least 6 months at the time of joining the trial. - People with Type 1 diabetes who have been taking multiple daily insulin injections for at least 3 months before the screening visit, are willing to dose me...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been admitted to an intensive care unit (ICU) - People who need their blood sugar levels monitored as part of insulin treatment Who may not be able to join: - People who are taking high doses of vitamin C (ascorbic acid) or more th...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been clinically diagnosed with type 2 diabetes - People whose blood sugar control measure (called HbA1c) is above 7% but no higher than 12% at the start of the trial - People whose treating doctor has decided to start...

**Who might be able to join this trial:** - People of any gender may be considered. - People between the ages of 14 and 50 years old. - People who have been diagnosed with diabetes within the last year, where the diagnosis was confirmed by blood sugar or HbA1c test results meeting specific levels (confirm with trial si...

Who might be able to join this trial: - Adults aged 18 or older who are actively involved in caring for a young person aged 12 to 21 who has been diagnosed with Type 1 Diabetes or asthma - The young person in their care must fall into one of these groups: has Type 1 Diabetes and a healthy weight, has Type 1 Diabetes an...

**Who might be able to join this trial:** **Part A:** - Adults aged 18 or older (men and women) - People who have been clinically diagnosed with type 1 diabetes for at least 12 months (no special blood tests are required to confirm the diagnosis — the doctor's judgment is used) - People who have been using multiple da...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with type 1 diabetes - People who have previously received a beta-cell replacement treatment, either an islet transplant or a pancreas transplant - People whose islet re-transplant (a second or repeat islet...

**Who might be able to join this trial:** - People who have Type 1 diabetes and manage it with either multiple daily insulin injections or an insulin pump - People whose HbA1c (a measure of average blood sugar over roughly 3 months) is between 6.5% and 9% - People with a body mass index (BMI) between 25 and 45 - Peopl...

Who might be able to join this trial: - People who have diabetes that requires insulin treatment - People who are between 7 and 17 years of age - People (and their parent or guardian) who are willing and able to sign the consent forms required to take part Who may not be able to join: - People who have a known skin se...

**Who might be able to join this trial:** - People aged 18 to 70 years, of any gender, who are considered generally healthy by the trial doctor based on a medical check-up, blood tests, heart monitoring, and breathing assessment. - People with no significant recent illness or surgery in the past 12 weeks, and no signi...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been clinically diagnosed with Type 1 Diabetes - People who have been prescribed one of two types of diabetes-related medications — either a GLP-1 receptor agonist or an SGLT inhibitor (SGLT-1 or SGLT-2) — by their doctor for any re...

**Who might be able to join this trial:** - Children and teenagers between 6 and 17 years old at the time of joining the trial - Children who have been diagnosed with type 1 diabetes by a specialist children's hormone doctor, following standard medical guidelines - Children who were diagnosed with type 1 diabetes with...