HIV and AIDS

Who might be able to join this trial: - Your current HIV treatment is not working well enough, and a recent blood test shows your HIV virus levels are at 1,000 copies per milliliter or higher - Your HIV virus is a specific type called "R5" (also known as CCR5-tropic), confirmed by a specific laboratory test called the...

**Who might be able to join this trial:** - You are HIV-1 positive - You have been taking a stable, daily oral HIV treatment (either 2 or 3 medications, with or without a booster) for at least 3 months before signing up, and your HIV levels in the blood have been undetectable (very low) during that time - You have nev...

**Who might be able to join this trial:** - People who are at least 18 years old (or older if local rules require it) at the time of signing the consent form. - People whose CD4+ T-cell count (a measure of immune system health) is above 200 cells per microlitre at screening. - People who have a confirmed HIV-1 diagnos...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have suitable veins that allow blood to be drawn easily. - People whose blood pressure is at or below 180/100, and whose heart rate is between 50 and 100 beats per minute (a lower heart rate may still be acceptable if it...

Who might be able to join this trial: - People whose HIV status has been confirmed through approved medical testing (such as a Western blot test or a blood test showing the virus is present in the bloodstream). - People aged 18 years or older. - People who are able to understand and sign a written consent form. - Peopl...

Who might be able to join this trial: - Adults aged 18 or older who have HIV-1. - People who have suitable veins for research blood draws. - People who have a confirmed positive HIV test result meeting current CDC standards, or — for those with a suspected very early HIV infection — a viral load above 2,000 copies/ml w...

Who might be able to join this trial: - You are HIV-1 positive and your HIV viral load (the amount of virus in your blood) is below 2,000 copies/ml without taking any HIV medications. - You are HIV-1 positive, taking a stable HIV medication regimen, your virus is undetectable in your blood, but your immune cells (CD4 T...

Who might be able to join this trial: - People (both children and adults) living with HIV who have previously taken part in HIV-NAT research studies - People (both children and adults) living with HIV who are currently taking part in HIV-NAT research studies - People who are able to provide written consent (for childre...

**Who might be able to join this trial:** - You have been diagnosed with HIV, confirmed by blood tests, or have lab results or symptoms that suggest you may possibly have HIV (confirm with trial site) - You are 18 years old or older - You are able to understand what the study involves and are willing to sign a consent...

Who might be able to join this trial: - People who have tested positive for HIV - People who are able to give their informed consent to participate - People who are willing to have blood samples taken and/or undergo a procedure that collects white blood cells from the blood (leukapheresis) - People who fall into one of...

Who might be able to join this trial: - People who are able to give their informed consent to take part. - People who have no medical reasons that would prevent them from having a surgical procedure. - People who have a noticeably swollen lymph node in the groin area that can be felt at the time of joining the study. -...

**Who might be able to join this trial:** **Treatment Group:** - People who are receiving care for HIV at one of the twelve participating clinics in the DC Cohort - People who are 18 years old or older, or younger people who manage their own HIV care independently and are able to understand and sign a consent form - Y...

Who might be able to join this trial: - People who do not have HIV and share similar background characteristics to the HIV-positive group in the trial - People who are HIV-positive and have never taken antiretroviral (HIV) medications - People who are HIV-positive and have been either on or off antiretroviral (HIV) med...

Who might be able to join this trial: - You are between 18 and 50 years old - If you are HIV-negative, you must have had specific blood tests confirming you do not have HIV (confirm with trial site for exact test names) - If you are HIV-positive, you must have had specific blood tests confirming your HIV status (confir...

**Who might be able to join this trial:** - People aged 18 or older - People with any HIV status (either HIV positive or HIV negative) - People who have at least two symptoms, lab results, or scan findings from at least two different categories that may be linked to a condition called KICS (Kaposi sarcoma herpesvirus...

**Who might be able to join this trial:** - You are infected with HIV-1 only (not also infected with HIV-2) - You are 18 years old or older when joining the trial - You are able to give written consent to participate - You are covered by French Social Security - You are willing and able to follow the requirements of t...

**This trial has three groups. Please read the section that may apply.** --- ## Group 1: People with PML (a serious brain infection) **Who might be able to join this trial:** - People with a suspected or confirmed diagnosis of PML - People whose MRI brain scan shows results consistent with PML - People who are able...

Who might be able to join this trial: - People who are 18 years of age or older. - People who are able to read, understand, and sign a consent form on their own. - People who have completed at least a seventh-grade level of education and can speak, read, and understand English — either as a native English speaker or as...

**Who might be able to join this trial:** **Mothers:** - Mothers who have either a presumed or confirmed HIV-positive test result taken around the time of giving birth (presumed results must be confirmed within 10 business days of joining the trial) - Mothers who are willing and able to sign a consent form for both th...

**Who might be able to join this trial:** *For people with HIV who have not recently been on treatment (ART-Naive Arm):* - People who have a confirmed HIV-1 diagnosis (records from other medical facilities are accepted) - People who have not been on combination HIV treatment in the past two years (those with very lim...

Who might be able to join this trial: - People who are at least 18 years old - People whose haemoglobin level (a measure of red blood cells) is above 11g/dL, checked by a finger-prick blood test - People who weigh more than 40 kilograms - People who have a confirmed HIV diagnosis, shown by a previous positive blood tes...

Who might be able to join this trial: - People who have given their informed consent and signed the required forms - People who are attending a health service or requesting a cervical cancer screening test - People who are willing and able to receive their test results by automated text message or by visiting the clini...

**Who might be able to join this trial:** - Adults aged 18 to under 60 years old who are living with HIV - People living with HIV whose recent blood test (within the last 6 months) shows an immune cell count (CD4) above 200 — or, if no recent test is available, those with an undetectable HIV level in the blood and a p...

Who might be able to join this trial: - People who have a confirmed HIV diagnosis - People who have been on combination antiretroviral therapy (a standard HIV treatment regimen) for more than 12 months - People whose HIV is well controlled, with very low virus levels in the blood (under 50 copies/ml) and a healthy immu...

**Who might be able to join this trial:** - People who have been recently diagnosed with HIV-1 infection, shown by early signs of infection along with specific incomplete blood test results, OR a negative HIV screening test in the past 6 months with incomplete follow-up test results, OR a known exposure risk in the pa...

**Who might be able to join this trial:** - People who are over 18 years old - People who are able to read and understand a written consent form - People who have HIV, and who either: are currently taking a combination HIV treatment (ART) regimen, have never taken HIV treatment, or have taken HIV treatment in the past...

**Who might be able to join this trial:** - You may be able to join if you are a patient with an already scheduled appointment at the outpatient clinic, regardless of your immune cell count (CD4) or whether you are currently on HIV treatment. **Who may not be able to join:** - No specific exclusion criteria have been...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People who do not have HIV - People attending a clinic for one of the following reasons: HIV screening, hepatitis screening, sexually transmitted infection (STI) screening or treatment, exposure to blood, body fluids, or sexual contact, po...

Who might be able to join this trial: - People who receive treatment at a medical practice that has enrolled in and is participating in this study - People whose treatment details are recorded in their practice's electronic health record system Who may not be able to join: - People who have chosen to opt out of the OP...

**Who might be able to join this trial:** - People who have been diagnosed with HIV and are receiving care for it, meaning they have had at least one HIV clinic appointment in the past six months - People who are 18 years of age or older - People who smoke at least 5 cigarettes per day and have done so for longer than...

Who might be able to join this trial: - Adults aged over 18 years, both male and female, who are living with HIV-1 - People who have been on a standard three-drug HIV treatment regimen for at least 24 weeks - People whose doctor has decided, for clinical reasons, that a two-drug simplified treatment (DTG+3TC) may be ap...

Who might be able to join this trial: - People who are already taking part in the SwissPrEPared program - People aged 16 years or older - People who have tested negative for HIV Who may not be able to join: - People who may have difficulty following the program's procedures, for example due to language barriers or men...

Who might be able to join this trial: - People who have HIV-1 infection - People who are older than 14 years of age - People whose HIV has shown resistance to all four main groups of HIV medications (known as NRTIs, NNRTIs, PIs, and INIs), meaning the virus is at least partially resistant to at least one medication fro...

**Who might be able to join this trial:** - People who have been diagnosed with plasmablastic lymphoma, confirmed through a tissue biopsy and specific laboratory testing of the cells. - People with stage II, III, or IV disease, or stage I disease where the tumour is larger than 7.5 cm or a specific blood marker (LDH)...

"Who might be able to join this trial: - People who are 15 years of age or older - People who are receiving care or treatment for HIV during the period when data is being collected for this trial - People from any background or group in terms of how HIV was transmitted to them Who may not be able to join: - There are...

**Who might be able to join this trial:** - People who are 15 years old or older - People who are receiving care for HIV during the period when data is being collected for this trial - People from any HIV transmission risk group are included **Who may not be able to join:** - There are no listed exclusion criteria for...

**Who might be able to join this trial:** - People who are 18 years of age or older - People of any gender - People who are living with HIV-1 (but not also infected with HIV-2) - People who receive their HIV care at the Regional Hospital of Orléans, France - People who fit into one of the specific patient groups liste...

Who might be able to join this trial: - People who are over 18 years old - People who have tested positive for HIV-1 through a specific blood test called a 4th generation Ag/Ab ELISA assay - People who have been on HIV treatment (antiretroviral therapy) that has kept their virus levels below 40 copies/mL for at least 2...

**Who might be able to join this trial:** - People who have been diagnosed with Kaposi sarcoma (KS) confirmed by a biopsy analysed at a specific laboratory (the Laboratory of Pathology, CCR). - People whose KS has spread enough that doctors recommend systemic (whole-body) treatment, or whose KS is causing physical sym...

**Who might be able to join this trial:** - People aged 18 to 60 years old at the time of screening - People who are able to give written consent, including agreeing to long-term follow-up - People who are willing and able to attend scheduled visits and provide blood samples - People who started HIV treatment (ART) wi...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a confirmed diagnosis of HIV-1 infection - People who have been on a stable HIV treatment regimen for at least 3 months - People whose HIV-1 viral load has been below 100 copies/ml within the past 3 months - People who do not have an...

Who might be able to join this trial: - People who are willing and able to sign a written consent form agreeing to participate - People who are 18 years of age or older - People who have a confirmed HIV diagnosis - People who have been on HIV treatment (antiretroviral therapy) for at least 12 months - People whose HIV...

**Who might be able to join this trial:** - People who have been confirmed to have HIV-1 infection at the screening stage - People who are either new to HIV treatment (never been treated before) or who are already on a stable HIV medication combination and have had very low levels of virus in their blood (fewer than 5...

Who might be able to join this trial: **For pregnant women (Component 1):** - Women who are pregnant and attending antenatal care (pregnancy check-ups) at the study site - Women who understand English or Swahili **For infants (Component 1):** - All babies born to enrolled women, regardless of how far along in pregnan...

**Who might be able to join this trial:** - People who have been diagnosed with HIV for at least 5 years - People who have been on combination HIV medication (multiple antiretroviral drugs together) for at least 3 years - People who have no HIV-related symptoms and no opportunistic infections (illnesses that take advan...

**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed with HIV-1 - Your CD4 cell count (a measure of immune system strength) is at least 200/mm³ - You have been on a stable HIV treatment regimen of at least 2 medications for at least 6 months - Your HIV viral load (the amo...

**Who might be able to join this trial:** - People aged 18 to 65 years old, of any sex - People who have been diagnosed with HIV-1 - People who have been on continuous HIV treatment for at least 12 months, with no breaks longer than 14 days in a row, and who have been on a stable treatment plan for at least 4 weeks th...

Who might be able to join this trial: - Adults aged 18 years or older - People who are residents of Miami-Dade County at the time of joining the trial - People who self-identify as Black - People who have had a viral load greater than 200 mL within the last 6 months, confirmed through a medical record or lab report bef...

**Who might be able to join this trial:** - Babies and toddlers between 3 and 18 months old who have normal hearing (Group A) - Babies and toddlers between 3 and 18 months old who have a certain type of hearing loss and are already wearing one or two hearing aids that have been properly fitted and adjusted by a hearing...

**Who might be able to join this trial:** - People who have a suspected non-spreading eye surface growth on one eye, where a specialist doctor has assessed that it can be surgically removed with a small clear margin around it, without affecting certain surrounding eye structures — this assessment must happen within 4...

Who might be able to join this trial: - Men who have sex with men and are living with HIV - Men who have sex with men and are not living with HIV Who may not be able to join: - People who have used testosterone supplements or anabolic steroids in the past year - People with a history of pituitary, adrenal, or gonad (r...

**Who might be able to join this trial:** - People who have a confirmed HIV diagnosis and are currently a patient at the UAB 1917 HIV Clinic - People between the ages of 19 and 65 - People living with HIV who are currently on a stable HIV medication (antiretroviral therapy) regimen - People without HIV who have a conf...

**Who might be able to join this trial:** - People who are 18 years of age or older - People whose immune system is weakened — this includes conditions or treatments such as HIV, organ transplants, certain cancers (including blood cancers), bone marrow transplants, autoimmune or systemic diseases, chemotherapy, long-te...

**Who might be able to join this trial:** - People who have been diagnosed with Kaposi sarcoma (KS), confirmed by the NCI Laboratory of Pathology. - People who have at least five measurable KS skin lesions that have not been treated with local radiation, surgery, or injected chemotherapy (depending on which group with...

Who might be able to join this trial: - You are female - You are between 15 and 24 years old at the time of joining the study - You are living with HIV and your HIV viral load (the amount of virus in your blood) has been undetectable (fewer than 40 copies/mL) within the last 6 months — or, for one specific part of the...

Who might be able to join this trial: **Step 1 (Initial enrolment):** - People aged 14 to 55 years, of any gender - People who have tested negative for HIV at the start of the study, following the testing process used at the trial site - People who are able and willing to give their informed consent to participate - P...

**Who might be able to join this trial:** - People who have a confirmed HIV diagnosis - People who are 18 years of age or older - People who receive their HIV care at the Johns Hopkins HIV Clinic - People who have a history of alcohol use disorder at some point in their lifetime - People whose clinical records from the...

Who might be able to join this trial: - Cisgender women and transgender individuals who have a reason to be offered HIV prevention medication (PrEP), and who have either decided to take PrEP, decided not to take PrEP, or decided to stop taking PrEP Who may not be able to join: - People who are unable to give informed...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have a confirmed diagnosis of HIV-1 or HIV-2 **Who may not be able to join:** - People for whom a blood draw or insertion of a small intravenous line (a thin tube placed into a vein) is not possible - People with severe an...

Who might be able to join this trial: **For people with normal hearing:** - Adults between 18 and 35 years old - Hearing test results showing no hearing loss across a standard range of sound frequencies - Able to give informed consent and follow experimental instructions - Normal vision, or vision that is fully correc...

**Who might be able to join this trial:** - People who are HIV-positive - People whose immune system is in a stable range, shown by a CD4+ T cell count above 200 cells/ml in a blood test - People whose HIV is well-controlled, with a very low amount of virus detected in the blood (fewer than 1,000 copies per mL) - Peop...

"Who might be able to join this trial: - People who are living with HIV. Who may not be able to join: - People who are not fluent in English. Important: Always verify eligibility with the trial site directly before applying."

Who might be able to join this trial: - People who have a confirmed diagnosis of primary HIV-1 infection - People aged 18 to 70 years old at the time of screening - People who are willing to use an effective method of contraception from the start of the trial until the end of the follow-up period - People who have a ne...

"Who might be able to join this trial: - People who have used opioid drugs in the two weeks before joining the trial Who may not be able to join: - People whose mental or physical health condition makes it difficult to take part in the trial Important: Always verify eligibility with the trial site directly before app...

Who might be able to join this trial: - People who are HIV-negative men who have sex with men, or transgender individuals, who are considered at high risk of getting HIV — this includes those who do not always use condoms with casual partners, or with HIV-positive partners who are not on treatment, or who have recently...

Who might be able to join this trial: - You are 18 years of age or older - You have been diagnosed with squamous cell carcinoma of the anal canal, confirmed by a tissue sample (biopsy), including a type called basaloid subtype - You have had a blood test to check for HIV infection - You can be at any stage of the cance...

Who might be able to join this trial: - People who are willing to give their agreement to take part in the study (informed consent) - People who are 18 years of age or older - People who have been diagnosed with high-grade anal dysplasia (a type of abnormal cell growth in the anal area), confirmed by a tissue biopsy -...

**Who might be able to join this trial:** - Female adolescents between 14 and 19 years old, of any racial background - People who have had sexual intercourse with a male in the last 3 months - People who have not always used condoms, or whose condom use has not been consistent or effective, in the last 3 months - Peopl...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are able to give informed consent to take part in a study - People whose situation means they are eligible to receive free HIV care services in Mexico - People who are living with HIV - People who have injected drugs in th...

"Who might be able to join this trial: - You must be able to speak, read, and write in Spanish - You must be 18 years old or older - You must be willing to take part in whichever group of the study you are assigned to - You must have an HIV-1 viral load (the amount of HIV in your blood) above 50 copies/mL, meaning the...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who attend one of the clinics selected for this study - People who have a confirmed HIV diagnosis, shown by a prescription for HIV combination treatment or a medication pack with their name on it - People who have been taking...

Who might be able to join this trial: - People who are 18 years of age or older. - People who have been diagnosed with HIV-1 using FDA-approved tests following CDC testing guidelines. - People who receive their regular HIV medical care at a location outside of the NIH (National Institutes of Health). - People who are...

**Who might be able to join this trial:** - People who have a confirmed HIV-positive diagnosis, verified by a lab report, medical records, or an HIV test. - People between the ages of 18 and 39 years old. - People who speak English or Spanish fluently. - People who are able to give informed consent and complete study...

**Who might be able to join this trial (recipients/patients):** - People who have a blood cancer that has been confirmed by laboratory testing and that doctors consider appropriate for a stem cell transplant from a related donor, including certain types of leukemia, lymphoma, myeloma, or related blood conditions (conf...

Who might be able to join this trial: - People who are living with HIV - People who have a uterine cervix (the lower part of the womb that connects to the vagina) Who may not be able to join: - People who are not able to give full, informed consent to participate - People who are currently pregnant, or who are not wil...

Who might be able to join this trial: - Adults aged between 18 and 80 years old - People who are HIV positive - People whose HIV virus levels are undetectable (virally suppressed) and have been on HIV treatment for at least 6 months - People who are already enrolled in specific studies run by Dr. Morris at the HLRC, or...

**Who might be able to join this trial:** - People who identify as cisgender female (born female and still identify as female) - People who have been diagnosed with HIV by a doctor, healthcare provider, or community health worker - People aged 18 years or older - People who can speak and read English or Spanish - Peop...

Who might be able to join this trial: - People aged between 21 and 70 years old - People who are able to understand and agree to take part in a series of brain and medical assessments - People who have used cannabis at least once in the past 5 years without serious negative reactions (such as psychosis or fainting) - P...

**Who might be able to join this trial:** - People who are cisgender men, non-binary individuals assigned male at birth, or transgender women or men - People who report having had anal sex with a person who was assigned male at birth in the last six months - People aged between 18 and 30 years - People who are visitin...

**Who might be able to join this trial:** - People who are 16 years of age or older (note: in Quebec, the minimum age is 18 years or older) - People who currently live in Canada as a resident - People who are able to give their consent in either English or French through a machine screen **Who may not be able to join:...

**Who might be able to join this trial:** - Adults between 18 and 75 years old, of any gender - People living with HIV whose virus levels in the blood have stayed below 1,000 copies/ml for the past 12 months - People who have been diagnosed with nerve-related pain (such as painful nerve damage, radiating pain, complex...

Who might be able to join this trial: - People who are women - People who have access to a working mobile or landline phone - People who have been involved with the criminal justice system at some point in their life, such as being on probation, parole, supervised release, or having been released from a prison or jail...

Who might be able to join this trial: - Adults aged 18 years or older. - People who are willing and able to follow the trial's requirements and attend follow-up appointments for the full duration of the trial. - People who have been given information about the trial, understood it, and are able to give their consent to...

**Who might be able to join this trial:** - People aged between 18 and 85 years - People living with HIV-1 who are on antiretroviral therapy (HIV medication) and have a very low level of virus in their blood (less than 200 copies/mL) at the screening visit - People who score 20 or higher on a standard depression questi...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have a confirmed HIV diagnosis - People whose CD4 count (a measure of immune system strength) is at or below 100 cells/mm³, tested within the past 4 weeks; OR people whose CD4 count has previously dropped to 100 cells/mm³ o...

**Who might be able to join this trial:** *For people living with HIV (PLWH):* - People who are willing and able to give written, signed consent to participate - Females who have a negative pregnancy test at the screening visit and on each scan day - People who have HIV and are on combination antiretroviral therapy (H...

Who might be able to join this trial: **For Aim 1:** - People who are male - People aged 15 years or older - People who have been given an invitation card by the study team to present at the site - People who are able to give informed consent to participate **For Aim 2:** - People who identify as cisgender men (born...

**Who might be able to join this trial:** - You identify as a cisgender woman (someone who was assigned female at birth and identifies as a woman) - You identify as Black or African American - You are 18 years of age or older - You are living with HIV - In the past 12 months, you have attended 1 or fewer HIV care appoi...

**Who might be able to join this trial:** - Women aged 18 or older - People who are able to give their consent to participate before the trial begins - People who are willing and able to follow all the requirements of the study - People who are living with HIV - People who are pregnant and starting combination HIV tre...

Who might be able to join this trial: - People who are living with HIV - People who are at least 40 years old - People who speak English Who may not be able to join: - People who have already been diagnosed with a heart or artery disease condition known as atherosclerotic cardiovascular disease (ASCVD) - People who ar...

Who might be able to join this trial: - People who are willing and able to sign and date a consent form agreeing to take part - People who are willing to follow all study procedures and lifestyle requirements, and who are available for the full duration of the study - Males and females between 18 and 75 years of age -...

**Who might be able to join this trial:** - People between 18 and 55 years of age. - People who are able to give their informed consent to participate. - People who are willing to allow their samples and data to be stored and shared for future research. - People who agree to use a barrier method of contraception (such...

Who might be able to join this trial: - People living with HIV who are being cared for at Amiens University Hospital and are not planning to move away within the next year - People who are able to attend follow-up appointments by video or phone consultation, as is standard practice at the service - People who are cover...

Who might be able to join this trial: - People who have a confirmed HIV-1 diagnosis. - People aged between 18 and 65 years (inclusive). - People who have been on combination HIV treatment (ART) for at least 2 years, and on the same treatment regimen for at least 4 weeks before the screening visit. - People whose HIV le...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with opioid dependence (according to standard medical guidelines) and have recently been prescribed and are consistently taking medication to treat opioid use disorder (such as methadone or buprenorphine) th...

**Who might be able to join this trial:** - People who identify as cisgender men, transgender women, transgender men, or non-binary individuals - People who have had anal sex without a condom with 2 or more male partners of different or unknown HIV status in the last 6 months - People aged 16 to 34 years old - People...

**Who might be able to join this trial:** **To enter the first phase (Step 1):** - People who have recent medical records confirming a new HIV infection, based on specific combinations of HIV test results taken within the past few weeks (confirm exact testing combinations with trial site) - People whose recent blood t...

Who might be able to join this trial: - People aged 18 or older. - People who have been recently diagnosed with an acute HIV-1 infection, confirmed through specific blood test results that indicate early-stage infection (the trial site can explain which stage applies in each case). - People willing to sign a consent fo...

Who might be able to join this trial: - People who are at least 18 years old - Cisgender men who have had anal sex without a condom with another man in the past 3 months - People who drink heavily, meaning either more than 14 drinks per week or having had more than 4 drinks on at least one occasion in the past month -...

Who might be able to join this trial: - People who are 18 years of age or older - People who are living with HIV - People who currently smoke cigarettes and have smoked at least 100 cigarettes in their lifetime, and currently smoke at least one cigarette per day - People who are willing to set a date to try quitting sm...

Who might be able to join this trial: - People who identify as Black or African American - People who identify as female - People who are between 18 and 30 years old - People who have recently used substances - People who have tested negative for HIV and are not currently taking PrEP (a medication used to prevent HIV)...

Who might be able to join this trial: - People who are between 15 and 34 years old - People who speak English - People who have recently started taking PrEP (an HIV prevention medication) for the first time within the last 30 days, or who have restarted PrEP after a break of at least 1 month - People who have tested HI...

Who might be able to join this trial: - You receive care at a Ryan White Clinic (a clinic that provides HIV care and services) that has been selected to take part in this study - Your clinic's leaders have completed a short survey about the clinic's characteristics and suitability for the study - You are either a staff...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a confirmed HIV diagnosis - People who currently smoke or use tobacco in more than one form, confirmed by a breath test showing carbon monoxide levels of 7 ppm or higher, or a positive cotinine test (a test that detects a substance le...

Who might be able to join this trial: - People who are 14 years of age or older - People who are fluent in English and/or French - People who are able to understand what taking part in the study involves and can give their consent to participate throughout the study - People who have access to a smartphone, tablet, or...

**Who might be able to join this trial:** This trial has three different groups of participants. Each group has its own set of criteria. **Group A: Women with a serious mental illness (SMI) and HIV** - People who have been diagnosed with a current psychotic disorder, mood disorder, or another condition causing diffi...

Who might be able to join this trial: - Adults who have been admitted to one of the hospitals taking part in this study - People living with HIV, whether or not they are currently taking HIV medications - People who have been diagnosed with a widespread form of a fungal infection called histoplasmosis, confirmed throug...

Who might be able to join this trial: **For young men who have sex with men (YMSM):** - People who identify as a young man who is romantically or physically attracted to other men - People aged 15 to 30 years old - People who have experienced at least one traumatic event in their lifetime, such as sexual assault, phys...

**Who might be able to join this trial:** - People living with HIV who have been on continuous HIV treatment and have had very low levels of HIV in their blood (below 200 copies/ml) for at least 12 months, confirmed at two or more clinic visits and at screening - People whose immune cell count (CD4+) has been above 35...

**Who might be able to join this trial:** - People who are living with HIV - People who are 50 years of age or older - People who receive their care at the Atrium Health Wake Forest Baptist Infectious Diseases Specialty Clinic (IDSC) - People who are eligible for the Ryan White Program (a program that helps people livi...

**Who might be able to join this trial:** - Adults or teenagers aged 15 or older who are living with HIV - People whose most recent HIV test showed the virus is not well controlled (more than 200 copies/mL in the blood), or who have not been taking HIV medication for at least 1 month - People who are not currently well...

**Who might be able to join this trial:** - You are 18 years of age or older - You can speak English or Spanish - You are willing and able to sign a consent form, share your contact information, and allow access to your medical records - You tested negative for HIV on a rapid HIV test - You have used a syringe services...

Who might be able to join this trial: **For the Clinician Survey group:** - People who currently work at a primary health care (PHC) or secondary health care (SHC) facility that is taking part in this study, and who agree to participate. **For the Continuing Professional Development group:** - People who currently wo...

Who might be able to join this trial: - People who are living with HIV. - People who meet the criteria for a substance use disorder involving illicit substances (not including tobacco, cannabis, or alcohol alone). - People who experience internalized stigma related to their HIV status, substance use, sexual orientation...

Who might be able to join this trial: - People who are 18 years of age or older - People who either tested positive for HIV using a rapid oral swab test at the trial location, or who have already been diagnosed with HIV (confirmed by an HIV clinic), and who have a low score on a measure of engagement with HIV care (a s...

Who might be able to join this trial: - Adults between 18 and 65 years old, of any gender - People confirmed to have HIV-1 infection, diagnosed according to Chinese national health standards - People who have tested positive for a hepatitis B surface protein (HBsAg) for more than 6 months, indicating a long-term hepati...

Who might be able to join this trial: - People aged 15 to 21 years who are visiting a pediatric emergency department. Who may not be able to join: - People who are not able to understand English. - People who are critically ill at the time of their visit. - People who have a cognitive impairment. - People who are expe...

Who might be able to join this trial: - People who have a confirmed HIV diagnosis - People who describe themselves as not very physically active — specifically, those who do less than 3 days per week of activity that makes them sweat, and who have not done regular strength/resistance exercise in the past 3 months - Peo...

**Who might be able to join this trial:** - People who are currently incarcerated at one of the participating study sites, whether awaiting trial or already sentenced. - People who have been diagnosed with HIV and are taking antiretroviral (HIV) medication at the time of joining the study. - People whose expected relea...

Who might be able to join this trial: - You are an adult living with HIV - You have been on a stable HIV treatment regimen for at least 3 months - Your HIV virus levels in the blood have been undetectable (below 50 copies/mL) for at least 6 months - A past HIV resistance test on your blood showed a specific genetic cha...

**Who might be able to join this trial:** - People who are between 18 and 24 years old - People who were assigned male sex at birth - People who identify as a gay or bisexual man, or as a transgender woman or another gender identity along the feminine spectrum - People who are living with HIV, as confirmed by their med...

**Who might be able to join this trial:** - People who are present at community events held at one of the "five points" locations — which include barbershops, hair or beauty salons, corner stores, grocery stores, neighbourhood restaurants, laundromats, or car service providers such as gas stations, mechanics, or car wa...

Who might be able to join this trial: - People living with HIV who are 18 years of age or older and have been diagnosed with early-stage syphilis - People whose syphilis has been confirmed through two specific blood tests (called RPR and TPPA) that show signs of active infection Who may not be able to join: - People l...

**Who might be able to join this trial:** - People who have given written consent to participate. - People who started combination HIV treatment within 90 days of being diagnosed with acute HIV infection. - People who have been on HIV treatment for at least 12 months, with no break in treatment longer than 28 days in...

**Who might be able to join this trial:** - People who are willing to give their agreement to participate and sign a consent form through an online system called REDCap - People who are willing to follow all study steps and are available for the full length of the study - People who can read in English or Spanish - Peo...

**Who might be able to join this trial:** **For "Index" participants (people who take on a peer educator role):** - People aged 18 or older - People who report having injected drugs in the past month - People who have used services at the needle/syringe program (SSP) in the past 3 months - People who are willing to at...

**Who might be able to join this trial:** - Adults aged 18 or older who have some level of vision loss caused by any eye condition - People who have recently received their first magnification device from one of the participating clinics — this includes devices such as handheld optical magnifiers, portable electronic v...

Who might be able to join this trial: - People who are pregnant, living with HIV, and attending an antenatal (pregnancy) clinic in southwestern Kenya - People who screen positive for probable common mental health disorders (such as depression or anxiety) at the clinic - People who live in the area served by the study c...

Who might be able to join this trial: - People who are eligible for VA Healthcare as a veteran - People who are able to travel to the VA Portland Medical Center for multiple visits - People whose hearing test results show sound can be heard at relatively soft levels across a range of pitches (no more than 30 dB HL at m...

"Who might be able to join this trial: - Women who are living with HIV Who may not be able to join: - No exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with the trial site directly before applying."

Who might be able to join this trial: - People who are at least 18 years old - People who live in one of the 50 specific areas identified by the Ending the HIV Epidemic (EHE) initiative, or in one of the 17 areas with the highest rates of HIV diagnoses among Latinx communities - People who identify as Latinx, Hispanic,...

Who might be able to join this trial: - People who have recently completed, or are currently taking part in, one of two specific earlier studies (HPTN 083 open label extension or HPTN 084 open label extension, including its pregnancy sub-study) and were receiving the long-acting cabotegravir (CAB LA) injection in that...

**Who might be able to join this trial:** - People who have a confirmed HIV infection - People whose HIV has progressed to AIDS, meaning their CD4+ cell count (a measure of immune system strength) is below 200 cells/µL and/or they have had infections linked to AIDS - People aged between 18 and 65 years old - People who...

**Who might be able to join this trial:** - People who have a confirmed HIV infection - People whose HIV has progressed to AIDS, meaning their CD4+ immune cell count is below 200 cells/ul and/or they have developed an AIDS-related opportunistic infection - People between 18 and 65 years of age - People who have been di...

**Who might be able to join this trial:** *(For mothers)* - A confirmed pregnancy, shown by a urine test or ultrasound - Aged 15 years or older - Meeting the local Malawi guidelines for PrEP (a type of HIV prevention medication) (confirm with trial site) - Testing HIV-negative using the local HIV testing process - Tes...

**Who might be able to join this trial:** - Black/African American and Hispanic/Latina cisgender women - People diagnosed with a substance use disorder (a condition where use of alcohol or drugs causes significant problems in a person's life), based on standard medical guidelines (DSM-5) - People who have tested negati...

Who might be able to join this trial: - People who are at least 25 years old - People who have been told by a medical professional that they have HIV - People whose annual income is up to 400% of the federal poverty threshold (for reference, the 2023 single-adult poverty threshold is under $14,580 per year) - People wh...

Who might be able to join this trial: - People who are HIV positive - People who are registered as a patient at one of the community health centres that are partnering with this trial, which focus on key populations - People who were male at birth - People who identify as young men who have sex with men, or young trans...

Who might be able to join this trial: - People who are 18 years of age or older - People who were male at birth - People who identify as a woman or transgender woman - People who are not currently taking PrEP consistently (meaning fewer than four doses per week) - People who have no known allergy or bad reaction to PrE...

Who might be able to join this trial: - People aged 18 to 50 years old at the time of joining the trial - People who are willing and able to read, sign, and date a consent form - People who can demonstrate an understanding of the study by passing a short quiz with a score of 90% or higher (within three attempts) before...

**Who might be able to join this trial:** - People who are currently pregnant - People attending antenatal care at Chitungwiza Central Hospital - People aged 15 or older - People who are willing to give their consent (or assent, for younger participants) to take part - People who have tested HIV negative - People who...

Who might be able to join this trial: - People who are blind or have significant vision impairment, either from birth or due to a condition that developed later, and have been living with this for more than 10 years - People who regularly use tactile aids (tools that convey information through touch) - People who have...

Who might be able to join this trial: - People who previously took part in the TEMPO-1 study - People who are 18 years of age or older - People who are either living with HIV or are part of a non-HIV control group - People who are enrolled in or covered by a social security scheme - People who have signed the consent f...

Who might be able to join this trial: - The mother must give her own voluntary and informed agreement to take part in the study (if she is participating herself) - A parent or legal guardian must give voluntary and informed agreement for the child to take part - The mother or legal guardian must be 18 years of age or o...

Who might be able to join this trial: - People who are 50 years of age or older - People living in a rural area, specifically in a county with a rurality score of 0.4 or higher on a standard rurality measurement index (confirm with trial site) - People living in one of these states: Alabama, Arkansas, Delaware, Florida...

Who might be able to join this trial: - You identify as Latino, Latina, Latinx, or Hispanic - You are 18 years old or older - You have HIV, confirmed by lab results in your medical records - You have been receiving care from a doctor who can prescribe HIV medication for at least 3 months - You currently receive your ma...

Who might be able to join this trial: **Healthy participants group:** - People aged 2 to 45 years old who are in good health - People (or their parents or legal representatives) who have given their voluntary agreement to take part - People who are willing to follow all study procedures, attend all visits for the full...

Who might be able to join this trial: - People between the ages of 25 and 49 years old - People who have a confirmed HIV diagnosis - People who are physically and mentally able to take part in the study and can give their informed consent to participate Who may not be able to join: - People who are currently pregnant...

Who might be able to join this trial: - People who completed one of the following specific earlier studies — GS-US-292-0106, GS-US-380-1474, GS-US-311-1269, or GS-US-216-0128 — and agreed to take part in this follow-on study. Who may not be able to join: - People switching to the study medication (B/F/TAF) on the firs...

Who might be able to join this trial: - The person must be in a married or live-in relationship with a partner. - At least one person in the couple must have screened positive for harmful alcohol use in the past 3 months. - At least one person in the couple must have been on HIV treatment (antiretroviral therapy) for a...

Who might be able to join this trial: - People who are currently receiving care at an HIV clinic in Alabama - People who have reported misusing opioids and/or stimulants - People who are 18 years of age or older Who may not be able to join: - People who have received substance use disorder treatment or care from a pro...

Who might be able to join this trial: - People who own and have access to a personal smartphone - People who are 18 years of age or older - People who speak English or Spanish - People who are living with HIV - People who either are not currently keeping their HIV virus levels low (virally suppressed), are not currentl...

Who might be able to join this trial: **People living with HIV (PLWH):** - People who are 18 years of age or older at the time of signing the consent form - People who speak English - People who are able to understand and follow the study requirements, as assessed by the clinic or study team - People who have a confir...

Who might be able to join this trial: - You identify as Latino or Hispanic. - You identify your sex as male. - You are 18 years of age or older. - You have been diagnosed with HIV and have been prescribed HIV treatment (antiretroviral therapy) for at least 1 month before joining the study. - You have had difficulty tak...

Who might be able to join this trial: - People who are living with HIV - People aged between 16 and 29 years old - People who feel confident reading and understanding English - People who have scored between 9 and 17 on a standard depression questionnaire called the PHQ-9, and whose daily functioning is affected (in li...

Who might be able to join this trial: - People who are 18 years of age or older (some countries may allow people aged 16 or older, depending on local rules) - People who have injected drugs at least once in the past month - People who are currently using a Needle and Syringe Program (NSP) to get injecting equipment, wh...

Who might be able to join this trial: - People who are between 18 and 54 years old - People who are cisgender men (born male and identify as male) - People who identify as Latinx - People who report being HIV negative - People who are willing to be tested for HIV - People who are willing to follow all study procedures...

**Who might be able to join this trial:** **For patients visiting the Emergency Department:** - People aged 12 years or older who are attending the Emergency Department in South Africa - For the part of the trial involving PrEP (a medication that helps prevent HIV), people who meet the medical requirements for PrEP an...

Who might be able to join this trial: - People aged 18 years or older who have HIV-1 and have received at least one dose of the long-acting injectable cabotegravir/rilpivirine (a type of HIV treatment given as an injection) between September 1, 2021, and March 31, 2024. Who may not be able to join: - No specific exclu...

Who might be able to join this trial: - People who identify as African American or Black - People between 15 and 26 years of age - People who live in, or spend most of their time in, Orleans Parish - People who have had vaginal sex at least once Who may not be able to join: - People who are unable or unwilling to give...

Who might be able to join this trial: - Adults aged 18 years or older - People who are HIV-positive - People who are currently taking antiretroviral therapy (HIV medication) - People whose HIV viral load has been undetectable for more than 12 months - People whose lowest-ever CD4 immune cell count (a measure of immune...

**Who might be able to join this trial:** - You are between 16 and 24 years old (inclusive) at the time of signing up - You are male or female - You report having anal or vaginal sex without a condom while using stimulants (such as crystal meth, cocaine, or MDMA/ecstasy/molly) in the 5 hours before or during sex, at le...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of Kaposi Sarcoma (proven by biopsy) with lesions that can be measured with a ruler. - People who have either two lesions at least 4mm x 4mm in size, or one lesion at least 8mm x 8mm in size, that can be biopsied — plus at least 5 additi...

**Who might be able to join this trial:** - People living with HIV (PLWH) who have been receiving care at one of 12 participating clinics in Philadelphia, were diagnosed with HIV at least one year before certain clinic measures are taken, had a Philadelphia address at the time of their HIV diagnosis, and have at least...

Who might be able to join this trial: - People who identify as Black - People who are living with HIV - People who identify as cisgender female (born female and still identify as female) - People who are 18 years of age or older - People who speak English - People whose HIV virus levels in the blood have not been fully...

Who might be able to join this trial: - People who are between 30 and 50 years old - People who have completed at least 8 years of schooling - People who speak Xhosa fluently - People who are HIV-positive - People who are currently taking antiretroviral therapy (ART), which is medication used to treat HIV - People who...

Who might be able to join this trial: - People who can speak, read, and write in English - People who are 18 years of age or older - People who are willing to take part in whichever group of the study they are assigned to - People who have an HIV-1 viral load greater than 200 copies/mL (a measure of HIV activity in the...

Who might be able to join this trial: - People over 18 years old who live in the community and have chosen to receive an HIV test from a traditional healer. Who may not be able to join: - People who are not in a clear state of mind or body at the time of recruitment — for example, those who are intoxicated or experien...

Who might be able to join this trial: **For Groups 1 and 2 (Step 1):** - People who are Thai nationals aged 18 to 60 years old who can read and write Thai - People who are willing and able to give written consent to participate - People who have a confirmed HIV-1 infection and who started HIV treatment (ART) during th...

**Who might be able to join this trial:** - People of any gender - People aged 15 years or older at the time of signing the consent form - People who weigh at least 35 kg - People who have a confirmed HIV-1 diagnosis - People who have received at least one dose of long-acting cabotegravir (CAB-LA) as HIV prevention (P...

**Who might be able to join this trial:** - People aged 18 or older who are willing to sign a written consent form, both male and female. - People who have been diagnosed with HIV for at least 12 months at the time of joining the trial. - People who are on oral HIV treatment (even if taken irregularly or with breaks),...

Who might be able to join this trial: **General entry (Step 1 — for younger children):** - People who were previously enrolled in the EIT/Tatelo or Moso Cohort Study - People who have been taking prescribed HIV treatment (ART) for at least 24 weeks before joining, based on records and reports - Children aged 24 weeks...

Who might be able to join this trial: - People who are currently studying nursing in their third or fourth year of training - People who are enrolled at a nursing school that is part of Kerman Medical University (KMU) Who may not be able to join: - Nursing students who are in their first or second year of training - S...

Who might be able to join this trial: - People who have been diagnosed with inflammatory bowel disease (IBD) according to specific medical guidelines - People who have complete medical history records available - People who are willing to take part in the trial and have signed a consent form Who may not be able to joi...

**Who might be able to join this trial:** - You are living with HIV. - You have visited a local VA (Veterans Affairs) healthcare site at least once in the past year. - A recent alcohol screening questionnaire (called the AUDIT-C) showed that you currently drink alcohol. - You are currently taking 5 or more medications...

Who might be able to join this trial: **For people living with HIV:** - People who are 18 years of age or older - People who have been diagnosed with HIV - People who are currently on HIV treatment (antiretroviral therapy) and whose HIV viral load (the amount of virus in the blood) has been below 200 in the past year...

Who might be able to join this trial: **For people who inject drugs (general public):** - People who inject drugs (such as opioids, amphetamines, or other injectable substances) who are starting HIV treatment at one of the study's HIV clinics — some may also have a diagnosis related to opioid dependence - People who a...

Who might be able to join this trial: **For young people living with HIV:** - People aged 15 to 24 who are living with HIV - People who are either new to HIV care (in care for one month or less) or who are returning to care after a gap of six months or more - People who speak English or Runyankole fluently - For one p...

**Who might be able to join this trial:** *For the main participants (African American men who have sex with men):* - You are an African American man who has sex with men, are over 18 years old, and have HIV - You own a working cell phone - You have been taking HIV medication (antiretroviral therapy) for at least 6 mo...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who are living with HIV - People who are currently taking a specific HIV treatment regimen that includes a medicine called dolutegravir as their first-line treatment - People who have had a gap in their HIV care (more than 28 days late...

**Who might be able to join this trial:** - People between 50 and 80 years old, of any gender - People living with HIV who have been on HIV treatment for at least 1 year, with the virus well controlled (very low or undetectable levels in the blood) and a healthy immune cell count - People who are not very physically a...

**Who might be able to join this trial:** - People who have been diagnosed with HIV, according to China's official HIV/AIDS diagnosis guidelines - People aged 40 years or older - People who are at risk of heart or blood vessel disease, either by having any two of the following: abnormal cholesterol or blood fat levels,...

Who might be able to join this trial: - Young women between the ages of 16 and 24 years old - People who are starting PrEP (a medication that helps prevent HIV) at the trial's recruitment location, and who have passed all the necessary health checks required to begin PrEP — including confirmed HIV-negative status, heal...

Who might be able to join this trial: - People who are 18 years of age or older - People living with HIV who are being monitored at the Trait d'Union/Infectious Diseases department in Strasbourg - People who received intermittent triple therapy (a type of HIV treatment given at intervals) at some point between 1 Januar...

Who might be able to join this trial: - People who were assigned male at birth and currently identify as a gender other than cisgender male (for example, transgender girl, non-binary, gender fluid, or unsure about their gender identity) - People aged 14 to 18 years old who have not yet graduated high school - People wh...

Who might be able to join this trial: - People who are between 50 and 75 years old - People who have been diagnosed with HIV by a healthcare professional, with confirmation provided at the start of the study (via a photo of a recent lab report or medication bottle showing their name) - People who have mild to moderate...

Who might be able to join this trial: **Sub-study 1 (records-based analysis):** - Young women and girls aged 15–24 living with HIV who were pregnant or had recently given birth, and who started HIV prevention services for pregnancy between January 1, 2018, and December 31, 2020. - Babies born to these young women duri...

**Who might be able to join this trial:** - People who are at least 18 years old but have not yet turned 51 on the day they sign the consent form. - People who are willing to follow the study rules and attend all required follow-up visits for the full duration of the study. - People who have understood the information...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with HIV/AIDS and have never previously received antiretroviral treatment (ART), either diagnosed between July 2024 and June 2025 (for the forward-looking part of the study) or between January 2020 and June 2023 (for the backward-lo...

**Who might be able to join this trial:** - People who are aged 18 to 70 years old - People who are able to give their informed consent to participate - People who have not previously received the Gardasil 9 HPV vaccine, or who are unsure of their vaccination history and were born before 2003 (having received a differ...

Who might be able to join this trial: - You are between 30 and 80 years old - You have a long-term condition that affects how well your immune system works - You have a history of high-grade abnormal cell growths in the lower genital area (confirm with trial site) - You are generally able to carry out daily activities,...

**Who might be able to join this trial:** - People who are either living with HIV or are considered at risk of getting HIV - People who have been diagnosed with a stimulant use disorder, or who have tested positive for cocaine, amphetamines, or methamphetamine in the last 6 months AND report using stimulants on at lea...

Who might be able to join this trial: - Adults aged 18 years or older - People who were assigned male at birth - People who have used methamphetamine at some point in the past 3 months (by their own report) - People who are either HIV-negative or do not know their HIV status at the start of the trial - People who have...

Who might be able to join this trial: - People who identify as Black - People who identify as cisgender female (meaning someone who was assigned female at birth and still identifies as female) - People aged 18 or older Who may not be able to join: - People who are under 18 years of age - People who do not identify as...

Who might be able to join this trial: - Both partners in the couple are male - Both partners are 18 years of age or older - Both partners report being in a committed relationship that has lasted at least 3 months - One partner is living with HIV and the other partner does not have HIV (known as a serodiscordant couple)...

**Who might be able to join this trial:** *For transgender women:* - People who identify as a transgender woman (assigned male at birth, with a feminine gender identity) - People between the ages of 18 and 65 - People who currently live in the Denver area - People who speak English or Spanish - People who have tested...

Who might be able to join this trial: - The people joining must be a couple who are married or living together, and have been together for at least 6 months. - One person in the couple must be a woman who is in the second or third trimester of pregnancy (between 3 and 9 months along) and is living with HIV. - The woman...

**Who might be able to join this trial:** - People who have been diagnosed with meningitis caused by a fungus called Cryptococcus, confirmed by a specific test on fluid from around the spine (called a CSF CrAg test) - People who are living with HIV - People who are able to understand and agree to take part by signing a...

**Who might be able to join this trial:** - Women aged 18 years or older - People who have a uterus - People who do not have HIV (based on self-reporting) - People who are not currently taking PrEP (a medication used to prevent HIV) - People who are comfortable having conversations in English or Spanish - People who a...

**Who might be able to join this trial:** - People aged between 60 and 75 years old - People whose first language is French - People who have given their consent to take part in the study - People who report having an active social life or hobbies that keep their mind engaged - People who score above 26 on a standard...

Who might be able to join this trial: - People who have been diagnosed with a probable or proven lung infection caused by a fungus called *Pneumocystis jirovecii* (also known as PCP), based on specific classification guidelines used by doctors. - People who have had laboratory and infection-related diagnostic tests com...

**Who might be able to join this trial:** - People aged 12 years or older who weigh at least 35 kg (about 77 pounds) at the time of signing up - People with a confirmed HIV-1 diagnosis, documented through standard approved HIV testing - People whose blood tests at screening show an HIV viral load (the amount of HIV in...

Who might be able to join this trial: - People who are receiving antenatal (pregnancy) care at one of the 5 participating clinics - People who are 18 years of age or older - People who are 34 weeks pregnant or less at the time of joining - People who are HIV-positive, confirmed by medical records - People who are start...

**Who might be able to join this trial:** - You identify as a Black cisgender woman (a woman assigned female at birth who still identifies as a woman) - You believe you are HIV-negative (do not have HIV) - You are 18 years old or older - You have had vaginal or anal sex without a condom with a male partner in the past...

Who might be able to join this trial: - Children who are already enrolled in a related study called the Tabiri study (research reference R01HD104552) - Children who were either born to an HIV-positive mother (but are themselves HIV-negative) or born to a mother without HIV - Children between the ages of 24 and 72 month...

Who might be able to join this trial: - People aged 18 to 55 years old at the time of signing the consent form - People who are generally in good health - People of any gender may be considered for this trial - People assigned female at birth may be considered if they are not pregnant, not planning to become pregnant,...

**Who might be able to join this trial:** - The trial site must be a syringe services program (SSP) — a program that provides clean needles and related support — located in an area identified by the CDC or the Ending the HIV Epidemic initiative as a high-priority or vulnerable location for HIV - The SSP must serve at...

Who might be able to join this trial: - People living with HIV who are 18 years of age or older - People who are currently being followed up at the HIV Clinic - People who have one or more of the following health conditions alongside HIV: high blood pressure, diabetes, high cholesterol or fats in the blood, fatty liver...

Who might be able to join this trial: - People aged 16 to 25 years old - People who identify as male or non-binary - People who were assigned male sex at birth - People who can read and understand English - People who own a smartphone - People who have had anal sex without a condom with a male partner in the past year...

Who might be able to join this trial: - Sexually active females between the ages of 15 and 39 years old - People who live in communities that are part of the Rakai Community Cohort Study (RCCS) and who took part in the most recent RCCS survey, regardless of HIV status - Pregnant women are also included - People who agr...

Who might be able to join this trial: - People who are over 18 years old - People who have exchanged sex for money, goods, or other payment at least once in the past 12 months - People who are living with HIV - People who are not currently taking antiretroviral (HIV) treatment - People who are already attending one of...

**Who might be able to join this trial:** - Adults between 18 and 34 years old - People who have tested negative for HIV using a rapid HIV antibody test - People who identify as gay or bisexual - People who have used methamphetamine in the past 3 months - People who have been prescribed HIV PrEP medication and are curr...

Who might be able to join this trial: - People who are already enrolled in the Ndovu cohort study - People who are able and willing to understand and follow the trial's requirements and instructions - People who are able and willing to give their informed consent to take part in this nested trial (for those under 18, a...

Who might be able to join this trial: - People who are able to collect their own vaginal sample themselves - People who are able to give their informed consent to participate in the trial Who may not be able to join: - People who are male - People who are younger than 25 or older than 50 years of age - People whose HI...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have a confirmed HIV diagnosis - People who have been on a stable HIV treatment plan, with the virus undetectable in their blood, for at least 12 months - People whose LDL ("bad") cholesterol level is above 140 mg/dL - People who cur...

Who might be able to join this trial: - People who are able and willing to give their consent to take part (for those under 18, a parent or legal guardian must also give consent) - People aged 1 year or older - People who have a confirmed HIV-1 diagnosis, confirmed using national HIV testing standards at the study site...

Who might be able to join this trial: - People who are living with HIV. - People who are living in a fishing community on most days or nights. - People who screen positive for potentially harmful drinking habits based on a standard questionnaire (a score of 4 or higher on a tool called the AUDIT-C). - People who have b...

Who might be able to join this trial: - You are over 40 years old - You are HIV-positive - You have been on a stable HIV treatment (antiretroviral therapy) for more than 6 months, with two recent test results showing the virus is undetectable in your blood - Your immune cell count (CD4) has been at a healthy level (abo...

**Who might be able to join this trial:** - People who are in good general health, confirmed through a screening check-up - People who can read English, complete study assessments, and agree in writing and verbally to take part *People living with HIV (all HIV-positive groups):* - People who have tested positive for...

**Who might be able to join this trial:** - People who were assigned male sex at birth - People between 18 and 65 years old - People who self-identify as Black, African-American, Afro-Caribbean, Black African, Afro-Latino, or multiethnic Black - People who live in the New York City metro area - People who do not have H...

Who might be able to join this trial: - Adults aged 18 or older - Men who have sex with men, aged over 30, who are living with HIV, and who meet French guidelines for anal cancer screening - People who have received a solid organ transplant (such as a kidney or liver) more than 10 years ago and meet guidelines for anal...

**Who might be able to join this trial:** - People aged 18 to 75 years old. - People who are able to give informed consent and are willing to follow all study procedures for the full duration of the trial. - People who are in generally good health and already have a regular doctor managing their HIV care, and who are...

**Who might be able to join this trial:** - People aged 18 to 64 years old - People who weigh at least 110 pounds - People with a Body Mass Index (BMI) between 18.5 and 40 (people with a BMI above 40 who are otherwise in good health may be considered with special approval) - People willing to receive the Jynneos (MPOX...

Who might be able to join this trial: - You are between 16 and 24 years old - You are getting tested for gonorrhea and/or chlamydia, either through a quick on-the-spot test or a standard laboratory test Who may not be able to join: - You have already been diagnosed with HIV - You are currently taking PrEP (a medicatio...

**Who might be able to join this trial:** - People who have served in the military as a veteran - People who are living with HIV - People whose HIV treatment uses a specific type of medication called an integrase strand transfer inhibitor, taken for at least 3 months - People whose HIV viral load is undetectable (less...

Who might be able to join this trial: **For "Index Participants" (the first person recruited into the study):** - Must be 18 years old or older - Must have used drugs in the past month - Must know other people in their social circle who also use drugs - Must be willing to talk with at least 2 people they know who use...

Who might be able to join this trial: - People who identify as a cisgender woman - People aged 18 or older - People who are HIV-negative - People who have had past involvement with the criminal legal system or child protective services - People whose alcohol use meets the criteria for being considered hazardous - Peopl...

**Who might be able to join this trial:** - People who are living with HIV - People who were assigned female sex at birth - People who are between 40 and 60 years old - People who are in the late stage of perimenopause (the transition leading up to menopause) or in the early stage of postmenopause (shortly after period...

**Who might be able to join this trial:** - People who have been given an official recruitment coupon — either by a clinic taking part in the study, or by another person already participating in the trial - People who are 18 years old or older - People who are able to take part in an interview conducted in English or...

**Who might be able to join this trial:** - People who have already started taking oral PrEP (a medication taken to reduce the risk of HIV infection), whether on a daily schedule or an event-based schedule, have picked up the medication at least once, and have taken at least one pill. - People who do not have HIV at t...

Who might be able to join this trial: - People who are 18 years of age or older - People who were assigned male sex at birth - People who identify as Black or African American - People who have had at least one male sex partner in the past 12 months - People who meet the CDC's eligibility guidelines for PrEP (a medicat...

**Who might be able to join this trial:** *For the HIV Case Finding part of the trial (which includes a PrEP component):* - People aged 15 to 24 - People who were assigned male at birth, regardless of their current gender identity - People who can understand basic English, Yoruba, Hausa, Igbo, or Pidgin English - For...

Who might be able to join this trial: - Be 18 years of age or older - Speak English as your primary language - Currently live in the United States - Have a gender identity that is different from the sex you were assigned at birth - Identify as a person of transgender experience - Have experienced two or more problems r...

**Who might be able to join this trial:** - You have been smoking cigarettes every day for the past 30 days - You are willing to share your HIV status with the study team - You are 18 years old or older - You want to quit smoking - You are willing to use nicotine replacement therapy (such as patches or gum) and a docto...

Who might be able to join this trial: - Men who are over 18 years of age - People who have already received two doses of the MVA-BN vaccine as their initial vaccination schedule - People for whom a booster dose of MVA-BN is recommended, according to French health authority (HAS) guidelines - People who are either start...

Who might be able to join this trial: - People who have been prescribed HIV treatment medication (antiretroviral therapy) - People who are willing to sign a consent form, which includes allowing the trial team to communicate with their primary HIV doctor Who may not be able to join: - People whose medical records show...

**Who might be able to join this trial:** *For Aim 2 of the trial:* - Adults aged 18 years or older - People who have been diagnosed with Kaposi Sarcoma confirmed through a tissue sample test - People who have at least 3 skin lesions from Kaposi Sarcoma - People who are able to understand and agree to participate in t...

Who might be able to join this trial: - People who are living with HIV-1 (a specific type of HIV) - People who are 18 years of age or older - People who have been informed about the study and have not objected to taking part - People who agree to use an electronic pill bottle cap (a device that records when the bottle...

**Who might be able to join this trial:** This trial has four separate groups (cohorts). A person may be considered for one group depending on their situation. **Group 1 (Clinic patients – new to HIV treatment):** - Adults aged 18 or older - Attending a participating clinic for HIV diagnosis or care - Not currently t...

Who might be able to join this trial: - Men who are living with HIV and whose virus has been kept at undetectable levels for at least 6 months using a specific combination of HIV medications: darunavir/cobicistat (800mg/150mg) plus tenofovir/emtricitabine (300mg/200mg) - People aged 18 to 70 years old - People whose ki...

Who might be able to join this trial: - People who are pregnant and attending antenatal (pregnancy) care appointments - People who identify as a cisgender woman - People who do not have HIV - People who are not currently taking PrEP (a medication used to prevent HIV) - People who are planning to stay in the same city o...

Who might be able to join this trial: - People aged 16 or older - People attending the Women and Infants Hospital of Rhode Island Family Planning Clinic for care - People who speak English or Spanish - People who are able to make their own decisions about participating (have decision-making capacity) - Doctors or physi...

Who might be able to join this trial: - You are 18 years of age or older - You are living with HIV - You are currently admitted to an internal medicine ward in hospital - Your hospital admission is related at least in part to a heart or metabolic health condition (such as diabetes or high blood pressure), either as the...

Who might be able to join this trial: - Adults aged 18 years or older - People who are registered patients at Parirenyatwa Hospital Radiotherapy Centre and are currently receiving cancer treatment for a newly diagnosed cancer - People who are HIV-positive Who may not be able to join: - People whose diagnosis is not ca...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People who started HIV treatment (ART) at Mildmay clinic or another clinic within the past 2 months - People who can speak and understand either English or Luganda - People who own a mobile phone or have regular access to someone else's ph...

Who might be able to join this trial: - People who are 16 years of age or older - People who have a confirmed pregnancy - People who have reported drinking alcohol at some point during their pregnancy, within the last 2 months - People who live within 20 kilometres of the study facility - People who are able and willin...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form - People who self-identify as a transgender woman - People who have a confirmed HIV-1 diagnosis, shown by at least two different blood tests or a measurable level of HIV in the blood - People who...

Who might be able to join this trial: - You must be a woman who is currently pregnant or have recently given birth, and be living with HIV (babies born during the study may also be included) - You must be 18 years of age or older - You must be receiving care through the PMTCT (Prevention of Mother-to-Child Transmission...

**Who might be able to join this trial:** - People who are between 15 and 24 years old - People who are at high risk of HIV, meaning they report at least one of the following in the recent past: having vaginal or anal sex with more than one partner whose HIV status is unknown (in the last 6 months); having vaginal or a...

**Who might be able to join this trial:** - People who are able to understand and sign a consent form agreeing to take part in the study - People who can read and follow instructions written in English - People who are willing and able to follow all study procedures - People who are planning to have one or more wisdom...

Who might be able to join this trial: - People who are between 14 and 17 years old - People who were assigned male at birth - People who have had oral or anal sex with someone who was also assigned male at birth - People who live in the United States - People who speak English Who may not be able to join: - There are...

**Who might be able to join this trial:** - People living with HIV who have missed a scheduled clinic appointment by more than 30 days and have not yet returned to care at the time of the sample being taken - People living with HIV who have come back to care after a period of being away and not taking HIV treatment, a...

**Who might be able to join this trial:** - People aged 18 years or older - People who are currently experiencing flu-like symptoms or an acute respiratory infection, including at least 2 of the following for between 2 and 7 days: cough, sore throat, fever, sneezing, congestion, muscle aches, fatigue, wheezing, or shor...

Who might be able to join this trial: - People aged 40 or older, or people who have been living with HIV for 25 years or more, of any sex - People whose HIV viral load is undetectable — meaning their last test result, taken within the past 6 months, showed fewer than 50 copies/ml - People who have at least one heart or...

Who might be able to join this trial: - People who have been diagnosed with HIV - People who receive their care at the Atlanta VA Healthcare System - People who are 18 years of age or older - People who meet the criteria for mild, moderate, or severe alcohol use disorder, as measured by two standard assessment tools (t...

**Who might be able to join this trial:** - People who have tested negative for HIV (both HIV-1 and HIV-2) - People who have been sexually active, specifically having had vaginal intercourse with a cisgender male partner at least twice in the last 3 months - People who were assigned female sex at birth and identify as...

Who might be able to join this trial: - People who are over 35 years of age - People who identify as part of a sexual or gender minority group, specifically men who have sex with men or trans women - People who are living with HIV - People who are able and willing to receive a package sent through the US Postal Service...

**Who might be able to join this trial:** - People of any gender are eligible to participate. - People who are currently being tested for syphilis for any reason — such as being at risk without symptoms, having symptoms, having had syphilis before, or being considered high risk — or people who have already been diagnos...

**Who might be able to join this trial:** - You are 15 years old or older - You are receiving care or services at one of the public health facilities taking part in this trial - You were not already known to be living with HIV before the specific visit when your health information was first collected for this study **...

**Who might be able to join this trial:** - People who have given written agreement to take part in the study - People who are in generally good health - People who have a current medical clearance from a doctor to practise sports - People with at least 4 years of training experience - People who complete a minimum of...

**Who might be able to join this trial:** - You have a confirmed HIV diagnosis, shown by a doctor's note, a positive HIV test result, or records of HIV medication being prescribed - You are 18 years old or older, as shown by hospital records or a government-issued ID - You live within the Matlosana sub-district (based...

Who might be able to join this trial: - People who have been diagnosed with HIV - People who have scored 5 or higher on a standard anxiety screening questionnaire called the GAD-7 - People who have scored 5 or higher on a standard depression screening questionnaire called the PHQ-8 Who may not be able to join: - Peopl...

Who might be able to join this trial: **For young men who have sex with men (YMSM):** - Men who are Vietnamese, aged 18 to 24 years old - Men who report having had anal sex with another man in the last 6 months - Men who are HIV-negative or do not know their HIV status - Men who own a smartphone - Men who currently li...

**Who might be able to join this trial:** - People who have been prescribed HIV treatment (antiretroviral therapy) that includes a medication called tenofovir. - People who have either shown signs that their HIV is not fully under control, had a urine test that showed no tenofovir was detected, or reported that they do...

**Who might be able to join this trial:** - You are 18 years of age or older and have a confirmed HIV diagnosis - You have been diagnosed with a specific type of liver fat disease (called MASLD), confirmed by an ultrasound, CT scan, MRI, or liver biopsy within the past 12 months - A specific MRI scan shows that at leas...

Who might be able to join this trial: - People aged 18 to 90 years old. - People whose best vision (with glasses or contact lenses) falls between 20/50 and 20/400 in their better eye. - People who have been diagnosed with an eye condition that causes vision loss. - People who have a combined field of vision of at least...

Who might be able to join this trial: - Teachers who teach Health and Family Life Education (HFLE) in Grade 6 at one of the 65 government primary schools taking part in the study, along with their classes. - Teachers who teach Health and Family Life Education (HFLE) in Grades 7 to 9 at one of the 30 middle schools acro...

Who might be able to join this trial: - People who have tested negative for HIV - People whose doctor has assessed that their recent behaviours could put them at risk of HIV exposure - People who have been regularly attending an opioid replacement therapy (a program that helps manage dependence on opioids) program at l...

**Who might be able to join this trial:** - A parent and their child (ages 8 to 21) who both speak English or Spanish, where the child has a spinal curve condition linked to a nervous system or muscle condition (called neuromuscular scoliosis) - The child is visiting a pediatric bone and joint specialist clinic to tal...

Who might be able to join this trial: - People who are living with HIV infection - People who are currently receiving antiretroviral therapy (medication to treat HIV) - People who live in the same administrative region (department) as the study hospital Who may not be able to join: - People who are currently pregnant...

Who might be able to join this trial: - Hearing levels that fall within the normal range (below 25 dB) across a standard range of sound frequencies in both ears. - Ears that appear healthy on examination, with clear ear canals, normal-looking eardrums, and normal middle ear function in both ears. - English speaking. W...

**Who might be able to join this trial:** - People who have a confirmed HIV diagnosis, documented by at least one standard HIV test (such as a rapid test, antibody test, or antigen/antibody test) and confirmed by a second method (such as a Western blot, a different antibody test, or an HIV RNA test). - People aged 18...

**Who might be able to join this trial:** - People who have given their formal agreement to take part and are willing and able to follow the trial procedures, as approved by the relevant review board. - Adults aged 18 to 100 years old at the time of giving consent. - People who are generally in good health, able to car...

Who might be able to join this trial: - People who are 15 years of age or older - People who are living with HIV - People who started HIV treatment (antiretroviral therapy) for the first time more than 3 months ago (people who have only very recently started treatment are not included) - People who are not currently pr...

Who might be able to join this trial: - People who are 40 years of age or older, both men and women. - People who have concerns or complaints about their memory or thinking. - People who are proficient in English. Who may not be able to join: - People who have had a sinus infection, thrush, candidiasis, a cold or flu,...

**Who might be able to join this trial:** - People aged 15 years or older who belong to one of the priority groups listed below (following an individual risk assessment by the trial site): - Female sex workers - Men who have sex with men - Transgender individuals - Women and adolescent girls and young women who are at...

**Who might be able to join this trial:** - People who are able to give written consent in English or Spanish - People who are living in specific areas: Western Connecticut; Dallas or Tarrant Counties in Texas; or Madison County, Kentucky (possibly Fayette County as well — confirm with trial site) - People who have ha...

Who might be able to join this trial: - Young women who are currently using or have previously used PrEP (a medication taken to prevent HIV infection) - Adult women and men from the community who are identified from the audience during the first performance in a round of plays - Adult women and men who heard about the...

**Who might be able to join this trial:** - People who have a confirmed HIV-1 diagnosis, documented in their medical records through an approved HIV test, antigen test, or viral load measurement - People who are 18 years of age or older - People who have been taking the same HIV treatment (antiretroviral therapy) cont...

Who might be able to join this trial: - You have hearing loss in both ears equally, ranging from mild to severe (but not total deafness), caused by an inner ear or nerve problem rather than a blockage. - A check of your ears shows that your ear canals are open, your eardrums look normal, and your middle ears appear hea...

Who might be able to join this trial: - People who are currently working as a healthcare provider, such as a clinician, nurse, or medical assistant - People who work in a clinical administration or leadership role within a PrEP clinic - People who work as a data manager, meaning someone who collects, enters, or manages...

Who might be able to join this trial: - Children between 18 months and 5 years old - Children who have a parent or caregiver present who is able to give formal written permission for their child to take part - Children who have not had an HIV test in the past three months - Children who have not previously been diagnos...

Who might be able to join this trial: **For people being interviewed as clients (service users):** - Adults aged 18 or older - People who have received services or taken part in programs at a partner community organisation in the past 12 months - People who currently live in the Philadelphia metropolitan area - People...

Who might be able to join this trial: - People who are women living with HIV (the trial aims to enroll 90 women, roughly 30 in each stage of menopause) - People who are participants at the San Francisco MWCCS site - People who are not currently pregnant Who may not be able to join: - Women whose HIV is not well contro...

**Who might be able to join this trial:** - You must be 18 years of age or older - You must be a current client of an organization called Unlocking Doors - You must be able to understand and agree to participate in the study on your own (give informed consent) - You must be willing to take part in conversations about g...

**Who might be able to join this trial:** This trial has several different groups of participants. People who meet the criteria for one of the following groups may be considered: **Group 1 – Pregnant or postpartum women living with HIV (Core Activity 1):** - People who are old enough and legally able to give their ow...

Who might be able to join this trial: - People aged 18 years or older - People whose immune system is weakened or suppressed — this includes organ transplant recipients, people with blood cancers or other cancers, people taking medications that affect the immune system, bone marrow or stem cell transplant recipients, a...

Who might be able to join this trial: - Adults between 18 and 60 years old, of any gender - People with a body mass index (BMI) between 18.5 and 29.9, and a body weight of at least 50 kg for men or at least 45 kg for women - People who have already been diagnosed with HIV-1 infection and have never taken any anti-HIV m...

**Who might be able to join this trial:** - People who have been diagnosed with Kaposi Sarcoma (KS) — a type of cancer — confirmed by a specific laboratory, whether or not they have had previous KS treatment - People who are living with HIV - People aged 18 or older - People who have at least five measurable KS skin l...

Who might be able to join this trial: - People who are 15 years of age or older - People who are living with HIV - People who are attending an ART (HIV treatment) clinic to start HIV treatment for the very first time - People who are attending an ART clinic to restart HIV treatment after missing a refill appointment by...

Who might be able to join this trial: - People who have HIV-1 infection. - People who have been continuously taking HIV treatment (antiretroviral therapy) for at least 48 months. - People whose immune cell count (CD4+ cells) was above 450 cells/mm³ when tested within the past 12 months. - People whose HIV virus level i...

**Who might be able to join this trial:** - People aged 18 or older at the time of screening - People who are willing and able to give written consent to take part in the study - People who are in good general health, based on medical history, physical check-up, vital signs, and lab test results at screening - People...

Who might be able to join this trial: - People who are living with HIV - People who are aged 75 or older - People who are enrolled in the social security system - People who have not objected to taking part in the study Who may not be able to join: - People who have refused to participate in the study - People with a...

**Who might be able to join this trial:** - People who understand the study and are willing to go through the formal consent process - People who are at least 18 years old at the screening appointment and no older than 55 years old on the day they enrol - People who are able to attend all follow-up clinic visits for t...

Who might be able to join this trial: - People between 18 and 55 years of age. - People who are able to visit a participating clinic and are willing to stay in the study for its full duration. - People who understand the study and are willing to give their informed consent to participate. - People who agree not to join...

**Who might be able to join this trial:** **Group A (people without HIV):** - You have tested negative for both HIV-1 and HIV-2 at the start of the study - Your doctor considers you to have a low chance of getting HIV, and you are committed to avoiding higher-risk behaviors throughout the study - You agree to talk ope...

Who might be able to join this trial: - Parents or legal guardians of children aged 0 to 13 years old who have been identified by a doctor in the Emergency Department as needing an urgent lumbar puncture (a procedure involving a needle inserted into the lower back to collect fluid) - Parents or guardians who speak Arab...

Who might be able to join this trial: - You are 18 years of age or older - This would be your first ever camera examination of your upper digestive system (such as your stomach and food pipe) - You are willing and able to sign a form agreeing to take part in the trial Who may not be able to join: - You are not able to...

Who might be able to join this trial: - Adolescents and young people between the ages of 15 and 22 years old - People who have been told about their HIV status by their healthcare team or caregivers - People who are currently taking antiretroviral medications (HIV treatment) - People who have completed at least up to G...

Who might be able to join this trial: - You are between 30 and 65 years old - You are in a vulnerable situation, such as receiving support from a government or local social service, or being referred by a charity - You live in one of the two towns or areas specifically included in this study - You are currently being s...

**Who might be able to join this trial:** This trial has three separate groups, and people may be eligible for one of them based on their situation: **Group 1 — People on HIV treatment:** - People who are 18 years old or older at the time they start or restart treatment - People who are starting HIV treatment for the...

Who might be able to join this trial: **For patients visiting the emergency department (ED):** - People who are able to understand the study and sign a written consent form before the study begins - People who test negative for HIV on a rapid test - People who meet at least one of the following: they asked their ED do...

Who might be able to join this trial: - People aged 18 or older - People with a medically confirmed HIV diagnosis - People who are willing to complete online surveys as part of the study - People who are willing to share their lab results with the research team - People who are willing to be randomly assigned to either...

Who might be able to join this trial: - People aged 18 years or older - People who are missing all teeth in one or both jaws, or who have teeth that cannot be saved, and who have already had dental implants placed with a temporary restoration and are waiting to receive their final permanent prosthesis - People who are...

Who might be able to join this trial: - People who have a confirmed HIV-1 diagnosis - People aged between 18 and 70 years old at the time of the screening visit - People whose CD4+ T cell count (a measure of immune system health) is above 300 cells per microlitre at screening - People who have never taken HIV treatment...

Who might be able to join this trial: - People who have been diagnosed with Visceral Leishmaniasis (a parasitic infection), confirmed by finding the parasite in spleen or bone marrow tissue — either at their first episode, a relapse, or as an ongoing active case where a doctor has decided treatment is needed - People w...

Who might be able to join this trial: - People who are 16 years of age or older - People who were assigned male at birth and currently identify as a transgender woman - People who are currently living in Ho Chi Minh City or nearby areas and have no plans to leave those areas in the next 6 months - People who have the m...

Who might be able to join this trial: - Adults aged 18 or older - People who are able to communicate in Thai - People who are willing and able to give their formal agreement to take part in the study Who may not be able to join: - People who are unable to take part in an in-depth interview, whether held online or in p...

**Who might be able to join this trial:** - Be between 18 and 29 years old - Have been assigned male at birth - Self-identify as a transgender woman or somewhere on the female spectrum - Have tested negative for HIV (confirmed by a lab test) - Have had sex without a condom recently - Be able to understand Thai - Not cu...

Who might be able to join this trial: - People who identify as a transgender woman, transgender man, or non-binary person - People aged 18 years or older - People who have tested negative for HIV - People who have used drugs or substances in a sexual context (sometimes called "chemsex") at least once in the past 12 mon...

**Who might be able to join this trial:** - People aged 18 to 55 years old - People with a body mass index (a measure of body weight relative to height) between 18.5 and 37.0 - Male participants must agree to use contraception or abstain from sexual activity during the trial (confirm with trial site for specific requir...

Who might be able to join this trial: - Adults aged 18 years or older - People who have a confirmed diagnosis of HIV infection - People who are already receiving care at one of the hospitals taking part in this trial - People whose medical records include relevant health information needed for dental care decisions, su...

**Who might be able to join this trial:** **For Aim 1 (Focus Group Discussion):** - People aged 18 or older who work in roles related to PrEP outreach or delivery in certain study areas — this can include both clinic and non-clinic roles - People aged 18 or older who are members of one of three regional community advi...

**Who might be able to join this trial:** - Women aged 18 or older who are at risk of HIV - Women who started a PrEP program (either an injectable or pill form of HIV prevention medication) at one of the 20 supported clinic sites in Blantyre - Women who missed their PrEP appointments by 3 months or more within the las...

Who might be able to join this trial: - People aged 15 years or older - Gay, bisexual, and other men who have sex with men - Transgender women and travestis - People from other sexual and gender minority groups - Cisgender women living in situations of social or economic vulnerability - Sex workers - People who are see...

**Who might be able to join this trial:** - You are 18 years of age or older and fall into at least one of the following five groups: - **Group 1:** You have tested positive for hepatitis B (but not HIV), you have not yet started treatment (or stopped treatment more than 1 year ago and have taken it for no more than 7...

Who might be able to join this trial: - People who are willing and able to sign a consent form agreeing to take part in the study. - People who were born male or female; women must either be unable to become pregnant or have gone through menopause (confirmed by a blood test at the screening visit). - People aged 18 to...

Who might be able to join this trial: - Adults aged between 18 and 65 years (inclusive) whose immune system has not fully recovered despite HIV treatment (known as incomplete immune reconstitution). - People who have been on antiretroviral therapy (HIV medication) for more than 4 years, with the virus being undetectabl...

Who might be able to join this trial: - Adults aged 18 or older who are living with HIV and currently taking antiretroviral therapy (HIV medications) - People whose HIV viral load (the amount of virus in the blood) has been below 20 copies/mL at two separate tests over at least 6 months, and whose doctor is planning to...

Who might be able to join this trial: **For young people:** - People who identify as a cisgender sexual minority male (such as gay, bisexual, or queer) - People aged 14 to 18 years old - People who have told a parent or trusted caregiver about their sexual orientation - People who are able to understand spoken English...

Who might be able to join this trial: - People aged 19 years or older - People using hormone treatments who have been on a stable, doctor-managed hormone regimen for at least 6 months and are able to continue that same regimen throughout the study - Females who are using a non-hormonal form of contraception and are wil...

Who might be able to join this trial: - Adults who are 35 years of age or older - People who are receiving care at a clinic in Botswana - People who have a recorded HIV status (positive or negative, as confirmed by the trial site) - People who are able to understand and agree to take part in the study Who may not be a...

**Who might be able to join this trial:** - People who are willing and able to sign a consent form and follow the study rules throughout the trial - People who are 18 years of age or older at the time of signing the consent form, of any gender - People who have been diagnosed with HIV infection and have a viral load o...