Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are female
• People with a Body Mass Index (BMI) of 30 or higher (this means a higher body weight relative to height)
• People whose knee shows no signs of arthritis on both X-ray and MRI scans
• People who have no knee pain, or knee pain on fewer than 15 days per month, in the knee being studied

Who may not be able to join:

• People who have symptomatic or severe heart artery disease
• People who are unable to walk without a walking aid or device
• People who are blind
• People who have type 1 diabetes
• People currently receiving treatment for cancer
• People who have had a knee fracture, or an ACL, MCL, or meniscus injury (with or without surgery) in the past 12 months
• People who have had an injection into the knee in the past 6 months
• People who have arthritis in both knees, as shown by X-ray or MRI scans
• People who have frequent pain in both knees on more than 15 days per month
• People with a BMI below 30
• People who are male
• People who experience claustrophobia (fear of enclosed spaces, such as an MRI machine)
• People for whom MRI scanning is not safe — for example, those weighing over 300 pounds, or whose knee does not fit the MRI equipment
• People who are unwilling or unable to make changes to their eating and physical activity habits due to their environment
• People who cannot speak and read English
• People who are planning to be away from the area for more than 2 months at any point during the 48-month study period

Important: Always verify eligibility with the trial site directly before applying.