Phase 3 Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have a confirmed diagnosis of Crohn's disease (CD)
• Your Crohn's disease is considered moderately to severely active
• You weigh at least 40 kilograms (about 88 pounds)
• You have tried at least one standard or advanced Crohn's disease treatment but it did not work well enough, stopped working, or you could not tolerate it
• If you are male or female and able to have children, you must agree to follow the trial's specific birth control requirements

Who may not be able to join:

• You have been diagnosed with ulcerative colitis, indeterminate colitis, ischemic colitis, infectious colitis, radiation colitis, or microscopic colitis (a different type of bowel condition)
• You have had 3 or more bowel removal surgeries where more than 2 sections of your bowel were removed
• You have been diagnosed with short bowel syndrome (a condition where much of the small intestine is missing or not working)
• You currently have an ileostomy, colostomy, or an ileoanal pouch (surgically created openings or pouches related to your bowel)
• You have painful or dangerous bowel blockages, severe colitis, or a life-threatening condition called toxic megacolon
• You currently have an abscess (a pocket of infection) in your abdomen or around your back passage
• You have certain types of abnormal connections (fistulas) between your bowel and other organs, or fistulas around your back passage with more than 3 openings
• You have or are suspected to have a liver condition called primary sclerosing cholangitis
• You are currently pregnant, breastfeeding, or planning to become pregnant during the study
• You have a current or past diagnosis of cancer in your digestive tract, or certain pre-cancerous changes in your colon
• You have a history of cancer outside the digestive tract, except for certain treated skin cancers or treated early-stage cervical cancer
• You have shown signs of infection with C. difficile, cytomegalovirus (CMV), HIV, Hepatitis B, or Hepatitis C during the screening process
• You have active tuberculosis (TB), untreated latent TB, or TB that has not been properly treated
• You have previously received or are currently taking a type of medication called anti-TL1A therapy, or other medicines listed as prohibited in the trial (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.