NCT03804866

Who might be able to join this trial:

• You are 18 years of age or older
• You have been diagnosed (confirmed by a tissue sample/biopsy) with advanced or metastatic ovarian cancer, fallopian tube cancer, or primary peritoneal cancer
• You have received no more than two previous chemotherapy treatments that included a platinum-based drug plus paclitaxel, and your cancer either did not respond to treatment or came back within 6 months of your last chemotherapy
• You are reasonably active and able to care for yourself, with only limited restrictions on daily activity (confirm with trial site)
• Doctors expect you to live for at least 12 weeks or more
• Your heart is functioning normally and your blood pressure is under control
• Your blood counts, liver, and kidney function are within acceptable levels as measured by blood tests (confirm with trial site)
• You have at least one area of cancer that can be tracked or measured and has not previously been treated with radiation
• If you have had surgery, radiation, or other cancer treatments, enough time has passed since your last treatment (at least 14 days after surgery/radiation, or 21 days after other cancer treatments)
• You are willing and able to sign a consent form agreeing to take part in the study

Who may not be able to join:

• You are currently taking part in another clinical trial involving an experimental treatment
• You have had more than two previous chemotherapy treatments, or you have previously been treated with a type of chemotherapy called an anthracycline
• You have had a heart attack in the last six months, have unstable chest pain (angina), moderate-to-severe heart failure, or a serious irregular heartbeat that requires medication
• You have an abnormal heart rhythm measurement on an ECG (a reading called QTc interval greater than 450 ms), whether inherited or developed
• You have a history of, or signs of, a condition affecting your brain or nervous system that has not been adequately treated (confirm with trial site)
• You have an active or poorly controlled serious infection or other serious health condition that would make participating unsafe
• You have a known allergy or sensitivity to human albumin or any of the ingredients used in the study drug
• There are personal, family, social, or location-related reasons that might make it difficult for you to follow the study requirements
• You are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.