NCT05231746

Who might be able to join this trial:

• You are 18 years old or older
• You are willing and able to give your signed agreement to take part in the study
• You have at least one tumour or lesion that can be measured on a scan, based on standard medical criteria
• You are able to carry out most daily activities with little or no restriction (confirm with trial site)
• You are expected to live for at least 12 weeks
• If you are able to have children (male or female), you agree to use contraception during the study and for at least 6 months after your last dose of the study treatment

Who may not be able to join:

• You have had any cancer treatment in the 4 weeks before starting the study
• You have had radiotherapy or major surgery in the 4 weeks before the screening visit
• You still have significant side effects from a previous cancer treatment that have not mostly cleared up before starting the study
• You have had a severe allergic reaction (grade 3 or higher) to a type of cancer immunotherapy drug called a checkpoint inhibitor
• You have notable abnormal results in blood or other lab tests (confirm with trial site)
• You have had another type of invasive cancer within the last 3 years
• Your cancer has spread to your brain or spinal cord and is currently active
• You need high doses of steroids or other medicines that suppress your immune system
• You have a history of an autoimmune disease that needed medical treatment in the past 2 years
• You currently have an active infection that requires treatment with antibiotics or antiviral/antifungal medicines
• You currently have an active hepatitis B or hepatitis C infection
• You have a known history of HIV infection
• You currently have active tuberculosis (TB)
• You have had a stroke, unstable chest pain, a heart attack, or severe heart problems in the 6 months before the screening visit
• You have a history of certain lung conditions, such as pulmonary fibrosis or drug-related lung inflammation, or signs of active lung inflammation on a recent CT scan
• You have previously had a stem cell transplant or an organ transplant from another person
• You test positive for COVID-19 during the screening period
• You have received a live vaccine within 30 days before the screening visit
• You have another underlying medical condition that may affect your eligibility (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.