Spravato (Esketamine)
esketamine 28 mg/2 actuations nasal spray, 2 x 2 actuations · NASAL · PBS code 14815R
AUTHORITY_REQUIREDWhat it costs
AU$294.16 PBS-determined price per 16 units
Most patients pay only the standard PBS co-payment, not the full price above — up to AU$25.00 per script (general) or AU$7.70 (concession/Safety Net) in 2026. The figure above is what the PBS pays the pharmacy; the Australian Government subsidises the rest. Always confirm the current amount with your pharmacist.
- • First listed on the PBS: 2025-05-01.
- • Repeats: 0.
- • PBS program: GE.
Eligibility criteria for subsidised access
The following is the government's own wording from the PBS Schedule, shown unchanged.
Listing of Pharmaceutical Benefits (NHL) - Schedule 4 part 1
Treatment resistant major depression
Induction treatment
The condition must have been inadequately responsive to at least two oral anti-depressant drug therapies; AND
Must be treated by a psychiatrist, where prescribing must also be completed by the treating psychiatrist; AND
Patient must be undergoing supervision at an accredited treatment centre for the administration of esketamine.
The following must apply if reinitiating treatment:
(i) at least four-week gap from last treatment course to reinitiation of treatment; and
(ii) evidence, documented in the patient's medical record using a structured rating scale, of significant clinical therapeutic benefit of the prior course of treatment with esketamine; and
(iii) evidence, documented in the patient's medical record using a structured rating scale, of a relapse in depression.
The listed quantity of 16 units of nasal spray is intended for a dosage of 56 mg per treatment administration in the induction treatment setting.
Sponsor: Janssen-Cilag Pty Ltd ABN 47 000 129 975
Not medical advice. Voxsanity republishes public PBS data in plain English. PBS listing status and criteria can change; always confirm current subsidised availability with your doctor or pharmacist.
Source: Pharmaceutical Benefits Scheme (PBS), © Commonwealth of Australia. Data used and redistributed under permission; not modified from its original wording where displayed verbatim.