Epilepsy Trial, Recruiting NCT02107989 Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Condition: Epilepsy
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Epilepsy Trial, Recruiting

NCT02107989
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Patients with epilepsy:

  • People aged 8 or older who have been evaluated or are being evaluated for epilepsy surgery under one of three specific NIH research protocols (18-N-0066, 11-N-0051, or 16-N-0041)
  • People with a confirmed diagnosis of focal epilepsy, supported by brain imaging (MRI), brainwave testing (EEG), and/or observation of seizure patterns
  • People who are able to give their own consent, or who have a parent, guardian, or legally authorised representative able to give consent on their behalf

Patients contributing data only (no active participation):

  • People who have already had epilepsy surgery with a pre-surgical evaluation done under protocol 18-N-0066
  • People who were aged 8 or older at the time of their epilepsy surgery evaluation
  • People who had a specific type of pre-operative brain MRI that matches what this study uses

Healthy volunteers:

  • People aged 8 or older who are able to give their own consent, or who have a parent or guardian able to give consent on their behalf
  • People who are able to cooperate with MRI scanning without needing anaesthesia

Who may not be able to join:

Patients with epilepsy:

  • People who have medical implants or devices that are not safe in an MRI or MEG scanner, such as pacemakers, cochlear implants, metal fragments in the body (shrapnel), or permanent eyeliner
  • People who experience claustrophobia or anxiety that is made worse by being inside an MRI scanner
  • People who are pregnant — a negative pregnancy test is required before scanning for anyone who could become pregnant

Patients contributing data only:

  • People who are not able or not willing to give consent, and who do not have a suitable representative who can give consent on their behalf

Healthy volunteers:

  • People who have medical implants or devices that are not safe in an MRI or MEG scanner, such as pacemakers, cochlear implants, metal fragments in the body, or permanent eyeliner
  • People who experience claustrophobia or anxiety that is made worse by being inside an MRI scanner
  • People who have significant medical conditions affecting the brain or nervous system, such as psychiatric conditions (including mood disorders, psychotic disorders, or substance use disorders), neurological conditions (such as brain injury, stroke, multiple sclerosis, epilepsy, or movement disorders), or ongoing systemic illnesses that may affect the brain (such as uncontrolled high blood pressure, autoimmune or inflammatory disorders, or cancer)
  • People who have taken medications that affect the brain or nervous system in the past 6 weeks — such as benzodiazepines, barbiturates, antidepressants, beta-blockers, or medications for epilepsy or migraine
  • People who are pregnant — a negative pregnancy test is required before scanning for anyone who could become pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Sara K Inati, M.D., National Institute of Neurological Disorders and Stroke (NINDS)

Phone: (301) 402-7686

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
11 March 2014
Est. completion
30 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

All outcomes in this study are Exploratory.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov