Type 2 Diabetes Trial, Recruiting NCT03842475 Sponsor: Imperial College London Condition: Type 2 Diabetes
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Type 2 Diabetes Trial, Recruiting

NCT03842475
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people planning weight-loss surgery:

  • You are planning to have a type of weight-loss surgery called a gastric bypass (RYGB)
  • You are between 18 and 80 years old
  • You have been diagnosed with Type 2 diabetes or pre-diabetes
  • Your weight has been stable for at least 3 months
  • Your body mass index (BMI) is 30 or above (classified as obese)
  • You qualify for this surgery through the NHS under NICE 2014 guidelines

For healthy volunteers:

  • You are between 18 and 80 years old
  • You are male or female
  • Your BMI is between 19 and 25 (considered a healthy weight range)
  • Your weight has been stable for at least 3 months

Who may not be able to join:

For people planning weight-loss surgery:

  • You are currently pregnant
  • You are unable to give your consent to take part
  • You have Type 1 diabetes
  • You have low levels of a substance called C-peptide, which is linked to insulin production (confirm with trial site)
  • You have diabetes caused by another condition, or your insulin-producing cells are not working (confirm with trial site)
  • You are unable to have a DEXA body scan, or you have liver disease, fluid build-up in the abdomen, cancer, or another condition that may affect body fat measurements
  • You are a current smoker
  • You have taken part in another clinical trial in the last 3 months
  • You are unable to understand English

For healthy volunteers:

  • You have abnormal blood sugar levels or an abnormal fasting glucose test
  • You have a medical condition or take any medications (including over-the-counter products) that the research team believe could affect the study
  • You do not have access to a telephone at home, or there is another reason you may find it difficult to take part reliably
  • You are pregnant or breastfeeding
  • You are unable to use adequate contraception for the full duration of the study
  • You have donated blood in the past 3 months, or plan to do so before the study ends
  • You are a current smoker
  • You have taken part in another clinical trial in the last 3 months
  • You are unable to understand English

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Tricia Tan, MB ChB, Imperial College London

Phone: +44208383242

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 October 2018
Est. completion
1 January 2025

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Diabetes remission (partial or complete); Diabetes remission (complete)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov