Epilepsy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are receiving a vagus nerve stimulator (VNS) implant for the first time as a treatment for epilepsy.
- People who have seen a neurologist based in Louisville within the past year, or — for those at the University of Utah or Baylor University sites — people with documented ability to travel to a neurologist at those locations.
- People with documented ability to travel to Louisville for outpatient medical care, or — for those at the University of Utah or Baylor University sites — people with documented ability to travel to those facilities.
Who may not be able to join:
- People who have previously been treated with a vagus nerve stimulator (other than the one being implanted as part of this study).
- People who are currently pregnant.
- People who currently have an active infection.
- People who have a history of cancer or have previously received chemotherapy.
- People who have a history of an autoimmune disease.
- People who have taken certain strong anticholinergic medications (a type of medication that blocks specific nerve signals) within 30 days before enrolling — those on moderate or lower-strength versions will be reviewed on a case-by-case basis by the lead researcher.
- People who begin strong anticholinergic medications after enrolling — the lead researcher will decide whether to delay, skip, or end participation in that case.
- People who have taken strong corticosteroids (a type of anti-inflammatory medication) within 30 days before enrolling — those on moderate or lower-strength versions will be reviewed on a case-by-case basis by the lead researcher.
- People who begin strong corticosteroids after enrolling — the lead researcher will decide whether to delay, skip, or end participation in that case.
- People currently taking medications used to treat irregular heart rhythms or to control heart rate.
- People who have a pre-existing irregular heart rhythm, or who have a cardiac pacemaker or implanted defibrillator.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 5026295512
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Metagenomic microbiome profile; Bowel movement frequency; Bowel habits; Immune Profile 1 - Flow cytometric profiling of cell populations; Immune Profile 2 - Ex vivo stimulation of cells in whole blood; Inflammatory Profile 1 - Meso Scale Discovery (or MSD) analysis for pro-inflammatory cytokines/chemokines; Inflammatory Profile 2 - Meso Scale Discovery (or MSD) analysis for metabolic hormones; Inflammatory Profile 3 - Metabolomics for Short Chain Fatty acids (SCFAs); Inflammatory Profile 4 - Intestinal inflammation and permeability markers
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.