Stomach Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been confirmed (through tissue samples, cell samples, or scans) to have metastatic cancer of the gastrointestinal system, including cancers of the esophagus, stomach, gastroesophageal junction, small intestine, liver, pancreas, bile ducts, colon, rectum, or anus.
• People who are currently receiving immunotherapy (a type of cancer treatment that uses the immune system) and whose cancer has continued to grow or spread despite that treatment.
• People who have at least two areas of cancer spread (metastases) that are each continuing to grow, where at least one of those areas can safely be left without radiation, as determined by the treating radiation oncologist.
• People who have between 1 and 5 areas of disease that a radiation oncologist considers appropriate for palliative (symptom-relieving) radiation — for example, disease causing pain, bleeding, difficulty breathing or swallowing, nausea, or placing important organs or tissues at risk.
• People who have been evaluated by a radiation oncologist within 28 days before joining the study.
• People whose organ function is sufficient to safely receive both radiation therapy and immunotherapy, as determined by standard medical assessment.
• People aged 18 or older.
• People with a life expectancy of more than 6 months.
• People with a reasonable level of physical functioning, as measured by standard medical scoring tools (confirm with trial site).
• People who are able to use reliable contraception during radiation therapy and for a period after, as radiation therapy is known to be harmful to a developing baby. Women of childbearing potential must have a negative pregnancy test within 28 days before joining. Men enrolled must also agree to use contraception during treatment and for 3 months afterward.
• People who are able to understand and willing to sign a written consent form.

Who may not be able to join:

• People who are already enrolled in an immunotherapy clinical trial that does not permit radiation therapy.
• People who have received radiation therapy within the 4 weeks before joining this study.
• People who are taking corticosteroids (steroid medications) or other medications that suppress the immune system in a way that would reduce how well immunotherapy works, as determined by the treating doctor.
• People for whom radiation therapy is considered unsafe or not appropriate, as determined by a radiation oncologist.

Important: Always verify eligibility with the trial site directly before applying.