Type 2 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Men and post-menopausal women with a body mass index (a measure of body weight relative to height) between 25 and 40
• People aged between 45 and 74 years
• Women who have confirmed menopause, based on a specific hormone blood test result (FSH ≥ 30 U/l)
• People who do not smoke
• People who do little structured exercise — less than 2 hours per week of activities like sports clubs or organised classes
• People who drink fewer than 2 alcoholic drinks per day

Who may not be able to join:

• People with LDL cholesterol (a type of "bad" cholesterol) levels above a certain threshold in their blood
• People assessed as having a high risk of heart disease (20% or more on a standard risk calculator) who would need immediate treatment with cholesterol-lowering medication
• People with a prior history of heart or blood vessel events, such as stroke, mini-stroke, heart attack, angina, or heart failure
• People with high blood pressure above certain levels (systolic above 140 or diastolic above 90)
• People with type 1 or type 2 diabetes, or elevated fasting blood sugar levels
• People who have had cancer within the last 3 years
• People with thyroid disease that is untreated or not yet stable
• People with anaemia (low red blood cell levels below a certain threshold)
• People with kidney problems or elevated kidney function markers in the blood
• People with liver problems based on certain blood test results
• People with blood clotting or bleeding problems
• People with autoimmune or chronic inflammatory conditions, such as celiac disease, inflammatory bowel disease, Graves' disease, multiple sclerosis, psoriasis, rheumatoid arthritis, or lupus
• People with a known history of difficulty having blood drawn from a vein
• People with claustrophobia
• People with sleep apnea
• People with a history of seizures
• People currently taking certain medications, including hormone replacement therapy (except stable-dose thyroid hormone), steroid tablets, anti-psychotic or psychoactive medications, blood thinners (such as aspirin, NSAIDs, warfarin, or coumadin), adrenergic agonists, blood pressure medications, weight-loss medications, or cholesterol-lowering medications
• People with a known history of substance abuse
• People already taking more than 250 mg per day of omega-3 supplements (EPA/DHA)
• People with an allergy to seafood or fish
• People with an allergy to Xylocaine (a local anaesthetic)
• People who are unable to eat the components of the study's high-fat test meal, which includes croissant, cheese, bacon, and brownies
• People who have not followed study requirements (such as arriving without fasting when required) or who have cancelled the same scheduled visit more than once
• People who do not have enough time to complete the full study, which runs for 33 weeks
• People who have already reached the maximum allowed radiation exposure for the year (from X-rays or scans), as determined by a doctor
• People with any other medical or psychological condition considered unsuitable by the trial doctor

Important: Always verify eligibility with the trial site directly before applying.