Stomach Cancer Trial, Recruiting NCT04842916 Sponsor: Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS Condition: Stomach Cancer
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Stomach Cancer Trial, Recruiting

NCT04842916
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with stomach cancer or cancer where the stomach meets the food pipe (oesophagus), confirmed by a tissue biopsy, and your cancer may be removable by surgery
  • You are currently being treated with standard chemotherapy drugs (such as 5-Fluorouracil or Capecitabine, combined with Oxaliplatin, with or without Docetaxel)
  • You are male or female and are over 18 years old
  • You are willing and able to sign a consent form agreeing to take part in the study
  • For the lookback part of the study (retrospective cohort): tissue samples and medical records from your previous treatment are available for review

Who may not be able to join:

  • You are under 18 years old
  • Your stomach cancer is at a very early stage, or is at stage T2 with no spread to nearby lymph nodes
  • You have a type of stomach cancer called linitis plastica (where the stomach wall becomes stiff and thickened)
  • Cancer cells have been found in the fluid around your abdominal organs, or the cancer has spread to the lining of your abdomen
  • Your cancer has spread to distant parts of your body (distant metastases)
  • You do not wish to take part in the study
  • You do not agree to allow your tissue samples to be used for research
  • You stopped your treatment early due to other health conditions or not being able to follow medical advice
  • You have a health condition that makes taking biological samples (such as blood or tissue) either unsafe or not useful for research (confirm with trial site)
  • You have a mental health condition that affects your ability to accurately complete questionnaires or follow medical guidance

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Registry
ClinicalTrials.gov
Start date
22 September 2020
Est. completion
22 May 2027

Where this trial is recruiting

🇫🇷 France 🇬🇷 Greece 🇮🇹 Italy

Primary endpoints

Genomic alterations in tumoral tissue in responders and non-responders; Quantitative and qualitative analysis of the tumor microenvironment composition in responders and non-responders; Analysis of cell-free DNA (cfDNA) from blood samples in responders and non-responders; Analysis of circulating tumor cells (CTC) from blood samples in responders and non-responders.; Peripheral blood mononuclear cells (PBMCs) and host immunity parameters in responders and non-responders

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov