Phase 2 Stomach Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults between 18 and 70 years old, of any gender
• People who have been diagnosed with stomach cancer (a specific type called gastric adenocarcinoma) confirmed by a lab test
• People whose cancer has not spread to distant parts of the body, and whose surgical team considers the tumour removable or potentially removable
• People who are relatively active and able to carry out daily activities (a medical scoring system called ECOG rates this as 0 or 1, meaning fully active or restricted in strenuous activity only)
• People whose cancer is at a certain stage — specifically stage T3/4 or has spread to nearby lymph nodes, based on a standard staging system
• People whose cancer cells test positive for a protein called PD-L1, with a score of 1 or higher on a specific lab test
• People who are expected to live for more than 3 months
• People whose heart, liver, kidney, and blood function meet certain minimum levels as measured by blood tests (confirm with trial site for specific numbers)
• People whose blood pressure is normal, or is controlled within a normal range with medication
• People with diabetes whose fasting blood sugar is controlled to a certain level with medication
• People who have hepatitis B must have a low enough level of the hepatitis B virus in their blood, as measured by a specific test
• People who have no other serious illnesses that would conflict with this study
• People with no history of any other cancer
• Women who could become pregnant must have a negative blood pregnancy test within 7 days before joining, and all people who could father or carry a child must use reliable contraception during the trial and for 6 months after it ends
• People who have read, understood, and signed a consent form agreeing to take part

Who may not be able to join:

• Women who are pregnant or breastfeeding
• People who had a serious infection in the 4 weeks before joining the trial
• People who have bronchial asthma that requires regular use of inhalers or other medical treatment
• People who have been taking immune-suppressing medications (such as prednisone at a certain dose) for more than 2 weeks due to another condition (confirm with trial site for specific dose details)
• People who have had significant heart or stroke-related conditions, including recent heart attack, severe chest pain, heart bypass surgery, heart failure, serious irregular heartbeat, reduced heart pumping ability, or a stroke within the past 6 months
• People who are allergic to any of the study drugs or their ingredients, or who have a history of severe allergic reactions
• People with severe mental health conditions
• People who have problems with blood clotting, a tendency to bleed, or who are currently receiving blood-thinning or clot-dissolving treatment
• People who have or have had lung scarring, lung inflammation, dust-related lung disease, radiation-related lung damage, or severely reduced lung function
• People who are unable to swallow the study medication, or who have ongoing digestive conditions (such as irritable bowel syndrome, Crohn's disease, or ulcerative colitis) or bowel blockages that may affect how the medication is absorbed
• People who have a weakened immune system, are HIV positive, have any other immune deficiency condition, or have had an organ transplant
• People who the research team determines do not meet the entry requirements for other reasons

Important: Always verify eligibility with the trial site directly before applying.