Autism Spectrum Disorder Trial, Recruiting NCT04972136 Sponsor: Centre for Addiction and Mental Health Condition: Autism Spectrum Disorder
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Autism Spectrum Disorder Trial, Recruiting

NCT04972136
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are fluent in English
  • People who have a confirmed diagnosis of Autism Spectrum Disorder (ASD) from a clinician or clinical team, and an IQ of 70 or above
  • People who are able to take part in the consent process, agree to join voluntarily, and can describe the main details of the study in their own words
  • People who have been clinically stable for at least 30 days, meaning no changes to psychiatric medications or increases in dose, and no changes to other treatments during that time, as determined by a doctor
  • People who score 21 or higher on a standard depression questionnaire (called the BDI-II), and whose score remains at that level over a two-week check-in period
  • People who score 60 or below on a standard functioning assessment (called the GAF), and/or score below adequate functioning on another assessment (called the VABS-III), with both measured consistently over a two-week check-in period

Who may not be able to join:

  • People who have had a substance use disorder (other than tobacco use) in the past six months, or who test positive for drugs at the start of the trial
  • People with a serious or unstable medical or neurological condition, as determined by the study doctor
  • People with metal implants or a pacemaker, or people who experience severe claustrophobia that would prevent them from having an MRI scan
  • People who are actively suicidal, meaning they have a plan and intent to end their life, or who are assessed by a study psychiatrist as being at high risk of suicide
  • People who have a history of seizures
  • People who are taking benzodiazepine medications at a dose equivalent to 2mg or more of Lorazepam, or who are taking any anti-seizure medication
  • People who have previously received rTMS (repetitive transcranial magnetic stimulation) treatment
  • People who are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Stephanie H Ameis, MD, MSC, Centre for Addiction and Mental Health

Phone: 416-535-8501

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre for Addiction and Mental Health
Registry
ClinicalTrials.gov
Start date
14 January 2021
Est. completion
14 January 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Change in scores on the 17-item Hamilton Rating Scale for Depression (HRSD-17)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov