Stomach Cancer Trial, Recruiting NCT05059444 Sponsor: Guardant Health, Inc. Condition: Stomach Cancer
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Stomach Cancer Trial, Recruiting

NCT05059444
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are over 18 years old
  • People whose cancer treatment is being given with the goal of curing or removing the cancer completely
  • People who are planning to have regular check-ups to monitor for cancer coming back, as part of their normal care at the enrolling hospital or clinic
  • People who are willing to sign a consent form agreeing to take part in the study
  • People who agree to have their de-identified (anonymous) health information shared with the research team at regular intervals as described in the study
  • People who are willing to provide blood samples when they join the study and at later check-up appointments, for up to 5 years
  • People who have provided at least one key blood sample called a "Landmark" sample
  • People who have a cancer confirmed by tissue testing that falls into one of the following groups:
    • Muscle-invasive cancer of the bladder, ureter, or the tube connecting the kidney to the bladder (stage II–III)
    • Non-small cell lung cancer (stage IB–III), either operable or inoperable
    • Invasive breast cancer where hormone receptor status and HER2 status are known, and the cancer is classified as high-risk HER2-positive, high-risk triple negative, or high-risk hormone receptor-positive/HER2-negative breast cancer
    • Skin melanoma at stage IIB–III, or a limited, surgically removable stage IV melanoma treated with curative intent
    • Cancer of the oesophagus or the junction between the oesophagus and stomach (stage II–III)
    • Stomach (gastric) cancer (stage II–III)
    • Pancreatic cancer that has been surgically removed or is eligible for surgical removal
    • Invasive squamous cell cancer of the head and neck, including cancers of the mouth, throat, voice box, and nearby areas (stage I–IVB)
    • High-risk ovarian or fallopian tube cancer (specific staging and tissue type criteria apply — confirm with trial site)
    • High-risk uterine (endometrial) cancer (2023 staging criteria stage II–III)
    • High-risk kidney (renal cell) cancer, including certain surgically removable stage IV cases treated with curative intent
    • Confirmed rectal cancer located in the lower part of the bowel that is undergoing or has undergone pre-surgery chemotherapy or immunotherapy treatment (exploratory group)

Who may not be able to join:

  • People who have previously received an organ or tissue transplant from another person
  • People whose cancer is primarily of a type called neuroendocrine (a specific tissue type — confirm with trial site)
  • People who have been diagnosed with another separate primary cancer within the 3 years before enrolling, with some exceptions — certain low-risk or early-stage cancers such as in situ cancers, non-melanoma skin cancers, low- or intermediate-risk prostate cancer, early thyroid cancer, and some cases of cancer in both sides of the same organ may still be eligible (confirm with trial site)
  • People whose cancer has spread to distant parts of the body at the time of joining, except for those with limited, surgically removable stage IV melanoma or kidney cancer

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Study Director, Guardant Health, Inc.

Phone: 8556988887

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Guardant Health, Inc.
Registry
ClinicalTrials.gov
Start date
7 September 2021
Est. completion
1 August 2029

Where this trial is recruiting

🇫🇷 France 🇩🇪 Germany 🇮🇹 Italy 🇪🇸 Spain 🇺🇸 United States

Primary endpoints

Distant Recurrence Free Interval (D-RFi)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov