Phase 3 Irritable Bowel Syndrome Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 75 years old
• You have been diagnosed with Irritable Bowel Syndrome (IBS) based on a specific set of standard medical guidelines called the Rome IV criteria
• Your IBS symptoms are at a moderate level of severity, based on a specific symptom scoring system (confirm with trial site)
• You regularly eat or drink foods that contain lactose, such as milk, cheese, or yogurt

Who may not be able to join:

• You are suspected of having a gut-related condition other than lactose intolerance or IBS, unless that condition has already been ruled out by tests
• You have already been diagnosed with lactose intolerance
• You have a known inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
• You have a known condition that seriously affects how your bowels move or function
• You drink more than 14 units of alcohol per week, or misuse other substances
• You currently have an active mental health (psychiatric) disorder
• You have a known condition affecting your whole body or immune system that also affects your digestive system
• You have had abdominal surgery in the past, except for an appendix removal
• You have ever been diagnosed with any type of cancer, except for a common, low-risk type of skin cancer (basocellular carcinoma)
• You are currently receiving chemotherapy
• You had a stomach or gut infection in the past 8 weeks
• You have taken antibiotics, prebiotics, or probiotics in the past 8 weeks
• You take dietary supplements, unless you have been on the same dose for more than 8 weeks
• You take nerve-related medications (neuromodulators), unless you have been on the same dose of just one such medication for more than 12 weeks
• You have taken certain gut-related medications — such as antispasmodics, opioids, or specific gut-lining treatments — in the past 8 weeks (confirm with trial site for specific medications)
• You have previously followed a low-fibre diet or a low FODMAP diet (a special diet that limits certain carbohydrates)

Important: Always verify eligibility with the trial site directly before applying.