Irritable Bowel Syndrome Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Healthy volunteers with no digestive or other major health conditions
- People with moderate to severe IBD (such as Crohn's disease or ulcerative colitis) whose disease is currently in remission but who still experience ongoing symptoms
- People with moderate to severe IBD whose disease is currently in remission and who have no symptoms
Who may not be able to join:
- Healthy volunteers who have a digestive disease or ongoing gut-related symptoms
- Healthy volunteers who have a psychiatric (mental health) condition
- Anyone who has had surgery on the back passage (anal area) or pelvis, including certain procedures during childbirth
- Anyone who has diabetes, heart disease, kidney disease, or liver disease
- Anyone currently taking or recently taking medications that affect gut function or mood (such as antidepressants), digestive supplements or herbal products (such as probiotics), or who has a history of heavy alcohol or drug use
- Anyone who has taken steroid tablets or injections within the last 2 weeks
- IBD patients whose disease is currently active (not in remission)
- IBD patients taking anti-diarrhoea medications or laxatives may still be considered, but would need to stop taking them for at least 48 hours before taking part (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Michiel van Nieuwenhoven, assoc prof, University Hospital Örebro
Phone: 0046196021794
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Rectal compliance testing with the HRAM and Barostat methods; Rectal sensitivity testing with whit the HRAM and Barostat methods; Anal squeeze pressure; Anal rest pressure; Anorectal coordination during simulated defecation; Dyssynergic defecation; GI symptoms based on the GSRS-IBS questionaire; GI symptoms based on the IBS symptom severity index; GI specific anxiety based on the Visceral sensitivity index; Symptom severity based on the Symptomatic severity module (PHQ 12); Assessment of personality using the NEO-FFI-3questionnaire (Big five inventory); Pathogenic variants; Genetical risk scor...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.