Phase 3 Type 2 Diabetes Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have stable coronary artery disease (a long-term heart condition affecting the arteries) and it has been more than 60 days since their last heart attack
- People who have diabetes
- People who are willing and able to give their formal written agreement to take part in the trial
Who may not be able to join:
- People whose heart is not pumping blood effectively enough (a heart pumping function below 50%)
- People who are currently experiencing a serious episode of heart failure that is not under control
- People who currently have an active infection, such as pneumonia or a skin infection, or who are currently taking antibiotics
- People who have an active inflammatory condition, such as rheumatoid arthritis, inflammatory bowel disease, or lupus, or who are currently taking anti-inflammatory medicines such as prednisone or methotrexate
- People who are currently pregnant (women of childbearing age will need a negative pregnancy test to be considered)
- People who are currently breastfeeding
- Women of childbearing age who are unwilling to use two forms of contraception for the duration of the trial, or men who are capable of fathering a child and who are unwilling to use contraception
- People whose kidneys are not filtering blood well enough (kidney filtration rate below 50 ml/min/1.72m²) (confirm with trial site)
- People who are currently taking certain medications that affect how the body processes drugs, including cyclosporine, verapamil, quinidine, ritonavir, clarithromycin, or ketoconazole (confirm with trial site if unsure about current medications)
- People with low levels of red blood cells, white blood cells, or platelets in their blood (confirm with trial site for specific threshold values)
- People with a history of liver scarring (cirrhosis), ongoing liver inflammation, severe liver disease, or significantly elevated liver enzyme levels
- People who are unable to give their formal written agreement to take part
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kevin Boczar, MD, Ottawa Heart Institute Research Corporation
Phone: 613 696 7000
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
TBR (Tissue-to-blood ratio) of the most-diseased segment (MDS) of the ascending aorta
Can't join this trial?
Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.