Phase 2 Autism Spectrum Disorder Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 6 and 18 years old at the time of joining the study
- Your body weight (BMI) is at or above the 5th percentile for your age
- You have been diagnosed with Autism Spectrum Disorder (ASD) by a specialist
- A parent or guardian is available to give permission for you to take part
Who may not be able to join:
- You have certain genetic conditions such as Fragile X syndrome, tuberous sclerosis, Williams syndrome, Angelman syndrome, Noonan syndrome, or other similar conditions that affect the heart or bone density
- You have another health condition that may cause low bone density, such as a hormonal imbalance (confirm with trial site)
- You take certain medications that can affect bone health, such as some anti-seizure drugs (like Phenytoin or Phenobarbital), steroid tablets taken by mouth, or a hormonal contraceptive injection called Depo-Provera (not including calcium or vitamin D supplements)
- You have low sodium levels in your blood (confirm with trial site)
- Your liver function blood test results are more than three times higher than the normal range
- Your kidneys are not filtering blood well enough, based on a specific blood test result (confirm with trial site)
- You have had a problem with substance or drug misuse in the last 6 months
- You have a history of serious heart problems, such as coronary artery disease, heart failure, irregular heartbeat, or an abnormal heart rhythm reading on an ECG
- You have had active seizures in the 6 months before joining the study
- You are pregnant, breastfeeding, or are sexually active and are not willing to use contraception
- You have received oxytocin (OXT) treatment within the 2 months before joining the study
- You are not able to cooperate with taking medication, having blood drawn, or having scans done, even with extra support and training
- Your caregiver is unable to speak English, cannot regularly attend study visits, or is unable to follow the study requirements
- You have any other serious illness, condition, medication, or medical device that the study doctor believes could interfere with the study or affect your safety
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Elizabeth A Lawson, MD, Neuroendocrine Unit Massachusetts General Hospital
Phone: 434-924-9141
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Difference between IN OXT vs placebo in 12-month change in whole body less head BMD Z-scores.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.