Phase 3 Irritable Bowel Syndrome Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are willing to give written consent to take part before any screening begins
• You have been diagnosed with Irritable Bowel Syndrome (IBS) that does not involve mainly constipation, based on standard medical criteria called Rome IV
• Tests have ruled out other conditions that could explain your symptoms, such as coeliac disease (blood test), lactose intolerance (breath test), inflammatory bowel disease, and a gut infection called giardiasis (stool test)
• If you have lactose intolerance, you may still be able to join if avoiding lactose for 6 weeks did not improve your symptoms
• You are between 18 and 65 years old

Who may not be able to join:

• You have a history of coeliac disease, food allergy, giardiasis, inflammatory bowel disease, stomach or gut infection, a gut movement disorder, serious liver, kidney, heart or lung disease, known heart rhythm problems, insulin-dependent diabetes, or a psychiatric illness
• You are currently pregnant or breastfeeding
• You are taking certain medications, including antidepressants, antipsychotics, antihistamines/allergy medicines, medicines that affect gut movement or sensitivity, most painkillers (only paracetamol is allowed), or certain other drugs that interact with how the body processes medicines — including some antibiotics, antifungals, heart medicines, and herbal products like St. John's Wort or grapefruit (confirm with trial site for the full list)
• Your IBS symptoms began after abdominal surgery
• Your IBS is mainly constipation-type (known as IBS-C)
• You have a known allergy or sensitivity to the active ingredient or any component of the trial medication (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.