Phase 2 Stomach Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any gender
• People with an advanced, spreading, or returning cancer that has been confirmed by a tissue or cell sample — mainly colorectal (bowel), esophageal (food pipe), stomach, or pancreatic cancer
• People whose cancer has continued to grow or who could not tolerate at least two rounds of standard treatments (such as surgery, chemotherapy, or radiotherapy), or for whom no effective standard treatment is available
• People whose tumor sample (taken within the last 3 months) tested positive for a protein called CEA in at least 10% of tumor cells, and whose blood CEA level is above 10 µg/L (confirm with trial site)
• People who have at least one measurable tumor that can be tracked during the trial, based on standard imaging guidelines
• People whose physical functioning falls within a certain range on a standard scale used by doctors to measure daily activity ability (called ECOG score 0–2) (confirm with trial site)
• People without serious mental health disorders
• People whose blood counts, heart, kidneys, liver, and oxygen levels meet specific healthy ranges as assessed by the trial doctors
• People who are physically able to have blood or cells collected for the treatment process
• People who agree to use reliable contraception for one year following the cell treatment (methods other than calendar-based rhythm methods)
• People, or their legal guardians, who agree to take part and sign a consent form after understanding the trial's purpose and procedures

Who may not be able to join:

• People whose cancer has spread to the brain or the lining around the brain, if the trial doctor considers this a concern
• People who have taken part in another clinical trial within the past month
• People who received a live attenuated vaccine (a type of vaccine containing a weakened live virus) within the 4 weeks before screening
• People who have recently received chemotherapy, targeted therapy, or other experimental cancer treatments (within 14 days or within a timeframe based on the specific drug — whichever comes first)
• People with an active or uncontrolled infection that requires ongoing treatment
• People with a bowel blockage, active bleeding in the digestive tract, or a history of digestive tract bleeding within the past 3 months
• People who still have significant side effects from previous cancer treatments (other than hair loss or mild nerve-related issues) that have not returned to near-normal levels
• People with certain serious heart conditions, including severe heart failure, a heart attack or heart bypass surgery within the past 6 months, significant irregular heart rhythms, unexplained fainting episodes, or a history of severe heart muscle disease
• People with an active autoimmune disease, or who need long-term use of medications that suppress the immune system
• People who have had or currently have another cancer that is not cured within the past 3 years — except for certain very early-stage cancers such as cervical carcinoma in situ or basal cell skin cancer
• People who test positive for Hepatitis B, Hepatitis C, HIV, or syphilis under specific testing conditions (confirm with trial site for exact details)
• People who are pregnant or breastfeeding
• People whom the trial investigators consider unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.