Phase 2 Stomach Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are able to understand and freely agree to sign a consent form to participate in the study
• You are between 18 and 75 years old (inclusive) at the time of signing the consent form
• Your cancer has been confirmed by a lab test (from a tissue or cell sample) to be a HER2-positive stomach cancer or cancer at the junction of the stomach and food pipe, and it has spread locally but not beyond a certain point
• You are generally able to carry out daily activities with little to no limitation (confirm with trial site for exact definition)
• Your heart is pumping blood effectively, with a pumping strength of at least 50% as measured by a heart scan
• Your liver is functioning within acceptable levels, based on blood tests taken within 7 days before starting the treatment (confirm with trial site for exact values)
• Your kidneys are functioning within acceptable levels, based on blood tests taken within 7 days before starting the treatment (confirm with trial site for exact values)
• Your blood counts and clotting levels are within acceptable ranges, based on tests taken within 7 days before starting the treatment (confirm with trial site for exact values)
• You are expected to live for more than 3 months
• You are willing and able to attend all required visits and follow all study procedures as set out in the study plan

Who may not be able to join:

• You have had, or currently have, another active cancer within the past 5 years
• You are planning to have, or have already had, an organ or bone marrow transplant
• You had a heart attack or poorly controlled irregular heartbeat within the 6 months before starting the trial
• You have a serious heart condition (grade III–IV) or your heart pumping strength is below 50%
• You are living with HIV (Human Immunodeficiency Virus)
• You currently have active tuberculosis (TB)
• You have a history of, or currently have, a lung condition such as interstitial lung disease, dust-related lung disease, radiation damage to the lungs, drug-related lung inflammation, or severely reduced lung function
• You have previously been treated with certain types of immunotherapy drugs, including PD-1, PD-L1, or CTLA-4 treatments
• You have any other serious health condition that the trial doctor believes would make it unsafe or unsuitable for you to take part

Important: Always verify eligibility with the trial site directly before applying.