Phase 1 Stomach Cancer Trial, Recruiting NCT06266299 Sponsor: Kyowa Kirin Co., Ltd. Condition: Stomach Cancer
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Phase 1 Stomach Cancer Trial, Recruiting

NCT06266299
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years old or older at the time of giving consent to participate
  • People whose cancer can be measured using standard imaging methods (a system called RECIST v1.1)
  • People who are relatively well and able to carry out daily activities, based on a standard health performance scale (ECOG score of 0 or 1)
  • People who are expected to live for at least 3 months, in the opinion of the study doctor
  • People for whom enough time has passed since finishing previous cancer treatments before starting this trial (confirm with trial site for specific timeframes)
  • People who agree to use an effective method of contraception during the trial
  • For one part of the trial (Part 1): People whose cancer is a solid tumour that has spread locally or to other parts of the body, confirmed by tissue or cell testing, and is not located in the brain or central nervous system
  • For another part of the trial (Part 2): People whose cancer is stomach (gastric) adenocarcinoma, cancer at the junction of the stomach and oesophagus (GEJ), oesophageal adenocarcinoma, or a type of lung cancer called non-small cell lung cancer (NSCLC), confirmed by tissue or cell testing
  • For Part 2: People whose doctor considers them suitable to receive a chemotherapy medicine called docetaxel

Who may not be able to join:

  • People who have a serious or uncontrolled illness alongside their cancer
  • People who have active cancer spread to the brain or central nervous system
  • People who have had a severe (Grade 3 or higher) allergic reaction to any antibody-based medicine in the past
  • People who have a history of autoimmune disease (conditions where the immune system attacks the body)
  • People who have a history of HIV, hepatitis B (HBV), or hepatitis C (HCV), identified during screening
  • People who have a history of a primary immune deficiency condition (a condition where the immune system does not work properly from birth or early life)
  • For Part 2 only: People who have previously been treated with docetaxel

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +81-3-5205-7200

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Kyowa Kirin Co., Ltd.
Registry
ClinicalTrials.gov
Start date
18 January 2024
Est. completion
1 March 2029

Where this trial is recruiting

🇯🇵 Japan 🇺🇸 United States

Primary endpoints

Number of Subjects Experiencing Dose-limiting Toxicity; Number of Adverse Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov