Irritable Bowel Syndrome Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 65 years old.
• You are able to understand and agree to take part in the study (give informed consent).
• Your gut symptoms (such as gas, bloating, stomach pain, loose stools, or hard stools) have been mild or very minor over the past 2 weeks, based on a standard symptom questionnaire.
• You are willing to eat the meals provided as part of the study.
• You are willing to avoid smoking during the breath testing parts of the study.

Who may not be able to join:

• You are pregnant, breastfeeding, or planning to become pregnant during the study.
• You have a history of a pre-existing gut or digestive condition that affects how your bowels work.
• You have previously had surgery to remove part of your food pipe, stomach, or intestines (not including the appendix).
• You have a stoma (an opening in the abdomen connected to the digestive system).
• You have a medical condition that could make taking part unsafe or difficult, such as diabetes, a breathing condition that would prevent you from using the breath testing device, or a known intolerance to any of the substances being tested.
• Your Body Mass Index (BMI) is below 18.5 or above 35 (confirm with trial site if unsure of your BMI).
• You are unwilling to follow the diet and lifestyle rules required during the study.
• You are currently taking certain medications that affect how the gut moves, such as mebeverine, opiates, or certain blood pressure or anxiety medications, and are unable to stop them for the duration of the study (confirm with trial site for the full list of affected medications).
• You are currently taking antibiotics or probiotic supplements, as these can affect the bacteria in your gut.
• You are not able to communicate in English well enough to take part.
• You worked a night shift (between midnight and 6:00 AM) in the week before your study day.
• In the opinion of the study team, you may have difficulty following the study requirements for any reason, such as cognitive difficulties or issues related to substance use.
• You have taken part in another research study in the last 3 months that involved invasive procedures or for which you received a participation payment.

Important: Always verify eligibility with the trial site directly before applying.