Phase 4 Epilepsy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 12 and 23 months old.
- You have a change (mutation) in the SCN1A gene that is known or suspected to cause problems, or you have been diagnosed with Dravet syndrome, and you have had at least one prolonged seizure.
- You have tried at least one seizure medication that does not belong to a group called sodium channel blockers (for example, not lamotrigine, oxcarbazepine, carbamazepine, or eslicarbazepine), and it did not work well enough.
- Your doctor must send in a detailed statement about your health history, including your diagnosis, gene result, other health conditions, seizure history, and past and current treatments.
- A heart scan (echocardiogram) must also be sent to the lead study site before you can be fully approved.
Who may not be able to join:
- Children who have a leaky mitral heart valve (mild or worse) or any leaking of the aortic heart valve may not be eligible.
- Children who are not gaining weight as expected — specifically, those whose weight is below the 2nd percentile, or whose weight gain has significantly fallen behind their height over time — may not be eligible, because the study drug can reduce appetite and cause weight loss.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kelly Knupp, MD, University of Colorado, Denver
Phone: 720-777-0717
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Percentage of participants that have at least one adverse event
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.