Phase 2 Irritable Bowel Syndrome Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Children who are between 12 and 17 years old and have been diagnosed with Irritable Bowel Syndrome (IBS) based on a specific set of medical guidelines called the Pediatric Rome IV criteria
Who may not be able to join:
- Children who have had surgery on their bowels, have a diagnosed gut/digestive condition (such as ulcerative colitis), or have a serious ongoing medical condition (such as diabetes)
- Children whose weight or height is significantly above or below the normal range for their age (confirm with trial site)
- Children who have a long-term health condition that also affects the digestive system, such as cystic fibrosis
- Children who have taken antibiotics or probiotic supplements within the last 3 months, as these can affect the natural bacteria in the gut
- Girls who are pregnant (a urine test will be done at the first visit to check)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bruno Chumpitazi, MD, MPH, Duke University
Phone: 919-660-1227
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in microbiome composition measured via taxonomic profiling using 16S ribosomal RNA gene amplicon sequencing; Change in fecal lactate; Change in fecal short-chain fatty acids; Change in hydrogen gas production; Change in fecal fructans
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.