Phase 4 Type 2 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For the Normal-Weight Diabetes group:

• People aged 30 to 70 years old who have been diagnosed with Type 2 Diabetes (or whose blood sugar results at screening confirm it).
• People whose HbA1c (a measure of average blood sugar over time) is between 5.7% and 8%, and whose diabetes treatment plan — whether medication or lifestyle changes — has stayed the same for at least 3 months.
• People with a body mass index (BMI) between 19 and 24.9 kg/m² (considered a "normal" weight range).
• People taking diabetes medications are generally welcome, except those currently using insulin or pioglitazone — other medications, including certain injectable diabetes drugs (GLP-1 receptor agonists), may be allowed if the dose has been unchanged for at least 3 months.
• People whose body weight has changed by no more than 2 kg over the past 3 months.

For the Normal-Weight Control group (no diabetes):

• People aged 30 to 70 years old with no diagnosis of diabetes and blood sugar results within the normal range.
• People with a BMI between 19 and 24.9 kg/m² who have never taken blood sugar-lowering medication.
• People whose body weight has changed by no more than 2 kg over the past 3 months.

Who may not be able to join:

• People who are pregnant, planning to become pregnant, or currently breastfeeding.
• People who have previously taken a diabetes medication called pioglitazone.
• People whose body weight has changed by more than 2 kg in the last 3 months.
• People with significant liver problems (based on a specific liver enzyme test result) or significant kidney problems (based on a specific kidney function test result).
• People with a history of heart failure or a condition involving excess fluid build-up in the body.
• People with high blood pressure that is not well controlled (above 160/90 mmHg).
• People who have been diagnosed with cancer in the past 3 years (skin cancer may be an exception — confirm with trial site).
• People with ongoing chronic inflammatory diseases.
• People currently taking weight-loss medications.
• People who have had weight-loss (bariatric) surgery or liposuction in the past.
• People currently using insulin.
• People with an active psychiatric condition or an eating disorder.
• People with a history of substance abuse.

Important: Always verify eligibility with the trial site directly before applying.