Hepatitis B Trial, Recruiting NCT06658782 Sponsor: University of Oxford Condition: Hepatitis B
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Hepatitis B Trial, Recruiting

NCT06658782
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing and able to give your consent to take part in the study
  • You are 18 years old or older, of any gender
  • Your doctor thinks you are suitable for routine liver cancer screening using ultrasound
  • Your liver is functioning at a level rated as Child-Pugh A or B (a measure of how well your liver is working — confirm with trial site if unsure)
  • You have been diagnosed with liver cirrhosis (scarring of the liver) caused by alcohol-related liver disease, a condition called MASLD (fatty liver disease), hepatitis C, hepatitis B, or a genetic condition called haemochromatosis
  • Your personal risk of developing liver cancer is calculated to be at least 3% per year, based on a specific scoring tool called the aMAP score
  • OR you have chronic liver disease and have previously been successfully treated for liver cancer, have had no return of the cancer, and are now attending routine 6-monthly liver ultrasound check-ups

Who may not be able to join:

  • You are unable to have an MRI scan for any medical reason
  • You have a known allergy or previous reaction to gadolinium contrast dye (a dye used in MRI scans)
  • You are currently in prison
  • You are pregnant or breastfeeding
  • You have previously had a liver transplant
  • You already have unclear or uncertain liver nodules (lumps) found on previous scans that are being monitored with MRI or CT scans
  • You have previously had liver cancer treated with the aim of curing it and are still having CT or MRI scans with contrast dye to check for it coming back
  • Your kidneys are not working well enough (based on a blood test result below a certain level — confirm with trial site)
  • You are currently receiving kidney dialysis (haemodialysis)
  • Your doctor feels you are unlikely to be able to follow the study procedures fully
  • Your doctor feels you have another serious health condition that may sadly be likely to lead to death within the next 12 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +44 1865234577

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 May 2025
Est. completion
30 April 2029

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Diagnostic performance for HCC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov