Phase 1 Stomach Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with colorectal cancer (confirmed by a tissue or cell sample) that has spread or cannot be removed by surgery, and it has continued to grow after receiving standard treatments (the exact number of prior treatments required depends on which part of the trial you would join)
- If joining the stomach/esophageal cancer arm (Arm E), you have been diagnosed with stomach cancer or cancer at the junction of the stomach and food pipe that has spread or cannot be removed, and it has continued to grow after at least one prior standard treatment
- Your cancer can be measured or assessed on scans (at least one measurable area of cancer is required for most parts of the trial)
- You are generally well enough to carry out everyday activities with little or no limitation (this is measured on a standard scale called ECOG, scores 0–1)
- Your kidneys are working at an acceptable level, based on a standard blood test measuring kidney function
Who may not be able to join:
- You have cancer that has spread to the brain and is new or getting worse, has spread to the membranes surrounding the brain or spinal cord, or you have untreated pressure on the spinal cord
- You still have significant side effects from previous cancer treatments that have not mostly resolved (with some exceptions, such as hair loss, certain nerve-related symptoms, or stable hormone-related conditions — confirm with trial site)
- You have or have had another cancer at the same time, unless it is very unlikely to affect the trial results or your safety (confirm with trial site)
- You have taken steroid medications (such as prednisone) at doses above 10 mg per day within the 7 days before starting the trial drug
- You have received or plan to receive a live vaccine within 4 weeks before starting the trial drug or within 4 weeks after your last dose
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC
Phone: 844-434-4210
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Part 1 and Part 2: Number of Participants with Adverse Events (AEs) by Severity; Part 1: Number of Participants with Dose-Limiting Toxicity (DLT)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.