Phase 3 Haemophilia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a man who has been diagnosed with hemophilia B and are 18 years of age or older
• Your Factor IX (a clotting protein in the blood) activity level is 2% or lower, meaning your hemophilia is severe
• You do not have inhibitors (antibodies that block) Factor IX treatment
• You have received Factor IX treatment products on at least 150 separate days in the past

Who may not be able to join:

• You have a blood or bone marrow disorder other than hemophilia B
• You have previously received any type of gene therapy, including a treatment called ANB-002
• You have HIV that is not being successfully controlled with antiviral medication
• You currently have an active hepatitis B (HBV) or hepatitis C (HCV) infection
• You have certain antibodies in your blood called anti-AAV5 antibodies (confirm with trial site)
• You currently have any active widespread infection in your body, or you frequently get infections that require strong medication
• You have any other condition that causes your immune system to be severely weakened
• You have significant liver disease or any condition that may be a sign of an existing liver problem
• You have had cancer, unless you have been in full remission for more than 5 years

Important: Always verify eligibility with the trial site directly before applying.