Phase 3 Haemophilia Trial, Recruiting NCT06716814 Sponsor: Swedish Orphan Biovitrum Condition: Haemophilia
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Phase 3 Haemophilia Trial, Recruiting

NCT06716814
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be able to give your agreement to take part, or if you are under 18 or unable to give consent yourself, a parent or legal representative must be able to do this on your behalf.
  • You must have already completed one of four specific previous studies (Sobi.BIVV001-001, Sobi.BIVV001-003, LTS16294, or Sobi.BIVV001-004) and the study doctor must believe you are benefiting from the treatment called efanesoctocog alfa.
  • You (or your parent or legal representative) must be willing and able to learn how to use a study diary app or form and fill it in throughout the trial.

Who may not be able to join:

  • You may not be able to join if a blood test at your first study visit shows that your body has developed a resistance to the treatment (called an inhibitor), at a level of 0.6 Bethesda units per millilitre or higher.
  • You may not be able to join if you are currently taking part in, or planning to take part in, another clinical study at the time of your first visit.
  • You may not be able to join if the study doctor decides for any reason — including your medical or health conditions, or concerns about your ability to follow the study procedures — that this trial is not right for you.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Medical Development Lead, Sobi AB

Phone: +46 (0)8 697 20 00

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Swedish Orphan Biovitrum
Registry
ClinicalTrials.gov
Start date
6 March 2025
Est. completion
1 March 2027

Where this trial is recruiting

🇧🇬 Bulgaria 🇫🇷 France 🇬🇷 Greece 🇮🇹 Italy 🇳🇴 Norway 🇪🇸 Spain 🇸🇪 Sweden

Primary endpoints

Number of injections to treat a bleeding episode; Total dose to treat a bleeding episode; Adverse events (AEs), including serious adverse events (SAEs) and adverse events of special interest (AESIs); Annualized bleeding rate (ABR) for treated bleeding episodes; Annualized bleeding rate (ABR) for treated bleeding episodes by type of bleed; Annualized bleeding rate (ABR) for treated bleeding episodes by location of bleed; Annualized bleeding rate (ABR) for all bleeding episodes; Annualized bleeding rate (ABR) for all bleeding episodes by type of bleed; Annualized bleeding rate (ABR) for all blee...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov