Phase 4 Type 2 Diabetes Trial, Recruiting NCT06727409 Sponsor: Chinese University of Hong Kong Condition: Type 2 Diabetes
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Phase 4 Type 2 Diabetes Trial, Recruiting

NCT06727409
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • You have been diagnosed with type 2 diabetes for at least 6 months
  • You have kidney disease with specific levels of kidney function and/or protein in your urine, within certain ranges (confirm with trial site)
  • Your blood potassium level is below a certain level at the screening appointment (confirm with trial site)
  • You are already taking one of two specific diabetes medications (dapagliflozin or empagliflozin) at a stable dose for at least 4 weeks
  • You are already taking a blood pressure medication from a specific group (ACE inhibitors or ARBs) at the highest dose you can tolerate without unacceptable side effects
  • In the opinion of the study doctor, you do not have any physical, mental health, or addiction-related issues that would make you unsuitable for the study

Who may not be able to join:

  • You have type 1 diabetes
  • You are allergic to, or cannot tolerate, certain blood pressure medications (ACE inhibitors or ARBs)
  • You are allergic to, or cannot tolerate, a type of medication called mineralocorticoid receptor antagonists (confirm with trial site)
  • You are allergic to, or cannot take, the class of diabetes medications called SGLT2 inhibitors
  • You are currently pregnant or planning to become pregnant
  • Your long-term blood sugar control (HbA1c) is above a certain level at enrolment (confirm with trial site)
  • Your blood pressure is too high (above 160 mmHg systolic) or too low (below 90 mmHg systolic) at enrolment
  • You are currently taking certain water tablets or hormone-related medications (eplerenone or spironolactone) that cannot be stopped
  • You have had a stroke or worsening heart failure in the 6 months before screening
  • You have had a serious diabetes-related crisis, extremely high blood sugar, or a heart attack in the 6 months before screening
  • You are currently on kidney dialysis, or are expected to need dialysis or a kidney transplant during the study
  • You are taking certain strong medications that affect how other drugs are processed in the body and cannot be stopped (confirm with trial site)
  • You have a condition called adrenal insufficiency (a problem with your adrenal glands not making enough hormones)
  • You are currently taking part in another clinical study that might affect this study's results
  • You are considered a protected or vulnerable individual, such as someone in detention or a prisoner

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Phone: +852 35051641

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
12 December 2024
Est. completion
31 July 2026

Where this trial is recruiting

Hong Kong

Primary endpoints

Change in urine albumin creatinine ratio (uACR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov