Phase 3 Spinal Muscular Atrophy Trial, Recruiting NCT06764485 Sponsor: Celgene Condition: Spinal Muscular Atrophy
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Phase 3 Spinal Muscular Atrophy Trial, Recruiting

NCT06764485
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must have been diagnosed with a specific type of prostate cancer (adenocarcinoma) confirmed by a tissue or cell sample, without certain aggressive features (small cell or neuroendocrine).
  • You must have prostate cancer that has spread to other parts of the body, shown by bone lesions on a bone scan or tumors seen on a CT or MRI scan.
  • You must have no pain or only mild pain from prostate cancer, with a pain score below 4 on a standard pain questionnaire.
  • You must have previously been treated with one of the following hormone-blocking medications: abiraterone, enzalutamide, apalutamide, or darolutamide.

Who may not be able to join:

  • You may not be eligible if you have a heart condition or significant heart disease that affects how well your heart works.
  • You may not be eligible if the cancer has spread to your brain.
  • You may not be eligible if the cancer has spread to your liver.
  • You may not be eligible if a bone scan shows an extremely widespread pattern of cancer spread throughout the skeleton (sometimes called a "superscan") (confirm with trial site).
  • There may be additional eligibility requirements not listed here that the trial team will check (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Australian sites

GenesisCare - Campbelltown, Campbelltown, New South Wales
0246344355
St Vincent's Hospital, Darlinghurst, New South Wales
+61293555655
Macquarie University, Macquarie University, New South Wales
+61298122956
Port Macquarie - Mid North Coast Cancer Institute, Port Macquarie, New South Wales
+61265814053
Sydney Adventist Hospital, Wahroonga, New South Wales
+61290561100
Greenslopes Private Hospital - Gallipoli Medical Research Foundation, Greenslopes, Queensland
0731766505
Tasman Oncology Research, Southport, Queensland
+61756132480
Royal Adelaide Hospital, Adelaide, South Australia
+61870742336
Lyell McEwin Hospital, Elizabeth Vale, South Australia
08 7117 7265
ICON Cancer Centre - Kurralta Park, Kurralta Park, South Australia
+61884740220
Icon Cancer Centre Hobart, Hobart, Tasmania
+61 3 6240 2600
Austin Health, Heidelberg, Victoria
+613 9496 5000
Cabrini Hospital - Malvern, Malvern, Victoria
+61 3 9508 1222
Peter MacCallum Cancer Centre, Melbourne, Victoria
+61385595000
The Alfred Hospital, Melbourne, Victoria
+61390763129
St. John of God Murdoch Hospital, Murdoch, Western Australia
+61863230011

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Celgene
Registry
ClinicalTrials.gov
Start date
13 March 2025
Est. completion
12 September 2027

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇦🇹 Austria 🇧🇷 Brazil 🇨🇦 Canada 🇨🇱 Chile 🇨🇳 China 🇨🇿 Czechia 🇩🇰 Denmark 🇫🇷 France 🇩🇪 Germany 🇮🇳 India 🇮🇪 Ireland 🇮🇹 Italy 🇯🇵 Japan 🇵🇱 Poland Puerto Rico 🇷🇴 Romania 🇸🇰 Slovakia 🇰🇷 South Korea 🇪🇸 Spain 🇸🇪 Sweden 🇹🇼 Taiwan Turkey (Türkiye) 🇬🇧 United Kingdom 🇺🇸 United States

16 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Radiographic progression-free survival (rPFS) by blinded independent central review (BICR) using Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 (soft tissue) and Prostate Cancer Clinical Trials Working Group 3 (PCWG3) (bone) criteria

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov