Type 2 Diabetes Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People in the "lean, normal blood sugar" group: those with a body weight in the normal range (BMI between 18.5 and 25), normal fasting blood sugar (below 95 mg/dL), normal results on a 2-hour sugar drink test (at or below 140 mg/dL), and a long-term blood sugar marker (HbA1c) at or below 5.6%.
- People in the "obesity, normal blood sugar" group: those with a BMI between 30 and 50, normal fasting blood sugar (below 95 mg/dL), normal results on a 2-hour sugar drink test (at or below 140 mg/dL), and an HbA1c at or below 5.6%.
- People in the "obesity, impaired fasting glucose" group: those with a BMI between 30 and 50, fasting blood sugar in the pre-diabetes range (100–125 mg/dL), and a 2-hour sugar drink test result below 200 mg/dL.
- People in the "obesity, type 2 diabetes" group: those with a BMI between 30 and 50, an HbA1c between 6.5% and 9.5%, fasting blood sugar at or above 126 mg/dL, a 2-hour sugar drink test result at or above 200 mg/dL, and/or a confirmed history of type 2 diabetes currently managed with diabetes medication.
Who may not be able to join:
- People using insulin at doses above 0.5 units per kilogram of body weight per day.
- People who have had any change in their diabetes medication within the past 3 months.
- People whose weight has changed by more than 2% in the 2 months before joining the study.
- People with significant health conditions affecting major organs, other than obesity or type 2 diabetes.
- People who regularly use tobacco products.
- People who drink alcohol heavily — defined as 3 or more drinks per day for men, or 2 or more drinks per day for women.
- People taking medications known to affect the study's measurements (such as steroids or certain cholesterol-lowering drugs) or that increase the risk of study procedures (such as blood thinners), if those medications cannot be safely paused for the study (confirm with trial site).
- People with anaemia, meaning a low red blood cell level (haemoglobin below 10.0 g/dL).
- People who are pregnant or breastfeeding.
- People who are unable or unwilling to follow the study procedures, or whom the research team considers unsuitable for any reason, including missed screening or medical appointments.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 314-273-1879
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Insulin secretion
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.