Type 2 Diabetes Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with Type 2 diabetes, based on the 1999 World Health Organization diagnostic guidelines
• People who are 18 years of age or older
• People whose urine and kidney function tests show a certain level of protein in the urine (UACR of 30 mg/g or more) and adequate kidney filtering ability (eGFR of 30 ml/min/1.73 m² or more), both present for more than 3 months
• People who have been taking a stable dose of a specific type of blood pressure medication (ARB or ACEI) for at least 4 weeks before joining the trial
• People who are willing to sign a consent form and follow the study's requirements

Who may not be able to join:

• People whose kidney disease was diagnosed before their Type 2 diabetes
• People with a high potassium level in their blood (above 4.8 mmol/L)
• People whose blood pressure is not well controlled at the screening visit (top number of 160 mmHg or more, and/or bottom number of 100 mmHg or more, based on an average of three measurements lying down)
• People whose blood sugar control is poor, with an HbA1c (a measure of average blood sugar over roughly 3 months) above 9%
• People with an active urinary tract infection or other conditions that could affect urine test results
• People with a condition where the adrenal glands do not work properly (primary or secondary adrenal insufficiency)
• People currently taking a type of medication called mineralocorticoid receptor antagonists
• People who have taken certain medications known to affect kidney protein levels or kidney filtering ability within the past 4 weeks (with some exceptions — confirm with trial site)
• People taking certain strong medications that affect how the body processes drugs (strong CYP3A4 inhibitors), including itraconazole, ketoconazole, ritonavir, nelfinavir, cobicistat, clarithromycin, telithromycin, nefazodone, or carbamazepine
• People with significantly elevated liver enzyme or bilirubin levels in their blood tests (above thresholds set by the trial — confirm with trial site)
• People who have used systemic steroid medications (such as oral, intravenous, or joint-injected corticosteroids) for more than 7 days in the 12 weeks before screening, or who have used them or needed immune-suppressing treatment in the past 14 days
• People who have had any type of cancer in the past 5 years, whether or not it has been treated
• People who are pregnant, breastfeeding, planning to become pregnant soon, or not using adequate contraception
• People who have taken part in another interventional clinical trial within the 3 months before screening

Important: Always verify eligibility with the trial site directly before applying.