Phase 3 Epilepsy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have had a specific type of genetic change in the SCN2A gene (called a "Gain of Function" variant), confirmed by genetic testing.
• People whose seizures started before they were 3 months old.
• People who have had 4 or more seizures involving physical movement (such as shaking or jerking) within every 28-day period during the initial observation phase of the trial.

Who may not be able to join:

• People who have another significant or known harmful genetic change — other than in the SCN2A gene — that could be causing or contributing to their epilepsy or developmental condition.
• People who have a bone, spine (such as abnormal curvature), bleeding, or other relevant medical condition (confirm with trial site for the full list of conditions that apply).
• People who have taken part in another clinical trial or used an experimental drug, device, or treatment within the past 30 days or within a certain time based on how long the drug stays in the body — whichever is longer — including anyone who has previously received gene therapy.
• People who are currently pregnant or breastfeeding, or who plan to become pregnant during the trial.

Important: Always verify eligibility with the trial site directly before applying.