Phase 4 Type 2 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older.
• People who have been diagnosed with type 2 diabetes, based on World Health Organization criteria.
• People who are currently taking a medication called an SGLT2 inhibitor at the highest dose that is tolerable for them.
• People who are currently taking a blood pressure medication known as an ACE inhibitor or an ARB, at the highest dose that is tolerable for them.
• People whose blood potassium level was 4.8 mmol/L or lower at the time of their screening appointment.
• People who have chronic kidney disease, defined as having a certain level of kidney function (eGFR of 25 or above) and a certain level of protein in the urine (confirm with trial site for exact values).
• People who speak and understand Danish fluently.

Who may not be able to join:

• People who are unable to give informed consent to participate.
• People with severely reduced kidney function (eGFR below 25 ml/min/1.73m²).
• People with severe liver disease, as shown by certain blood test results.
• People with an active cancer diagnosis, other than a common type of skin cancer called basal cell carcinoma.
• People who are taking steroid medications affecting the whole body at the time they would be assigned to a treatment group.
• People who have had weight-loss (bariatric) surgery in the past 2 years, or other bowel or stomach surgeries that cause long-term problems with absorbing nutrients.
• People who have had issues with alcohol or drug use within the 3 months before giving consent, or who have any ongoing condition that may make it difficult to follow the trial procedures reliably.
• People with chronic or acute inflammation of the pancreas (pancreatitis).
• People who are pregnant or breastfeeding.
• People with a poorly controlled serious medical condition, such as severe heart failure, a stroke or heart attack within the past 3 months, or any other condition the trial investigator considers too risky for participation.
• People who are allergic to the trial drug (finerenone) or any of its ingredients.
• People currently taking certain medications that strongly interact with how the body processes the trial drug (confirm specific medication names with the trial site).
• People currently taking other medications in a class called mineralocorticoid receptor antagonists (MRAs), such as spironolactone or eplerenone.
• People with rare inherited conditions affecting how the body handles certain sugars, including galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption.
• People with a condition called Addison's disease, which affects the adrenal glands.
• People who are unable to have an MRI scan.
• People who have previously had a kidney or heart transplant.

Important: Always verify eligibility with the trial site directly before applying.